Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation

Cancer Research

Volumn 67, Issue 8, 2007, Pages 3845-3852

  Tsai, Mong Hsun ^a,b   Cook, John A ^a   Chandramouli, Gadisetti V R ^a   DeGraff, William ^a   Yan, Hailing ^a   Zhao, Shuping ^a   Coleman, C Norman ^a   Mitchell, James B ^a   Chuang, Eric Y ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; STAT1 PROTEIN; VASCULOTROPIN;

ARTICLE; BREAST ADENOCARCINOMA; CANCER SURVIVAL; CELL CYCLE; CELL DIFFERENTIATION; GENE CONTROL; GENE EXPRESSION; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROSTATE CARCINOMA; RADIATION DOSE; RADIATION EXPOSURE; RNA ISOLATION; SOLID TUMOR; TUMOR GROWTH; UPREGULATION;

ANIMALS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CLUSTER ANALYSIS; DOSE FRACTIONATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENES, P53; GLIOMA; HUMANS; INTERFERONS; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROSTATIC NEOPLASMS; TRANSFORMING GROWTH FACTOR BETA; TRANSPLANTATION, HETEROLOGOUS; UP-REGULATION;

EID: 34248545443     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-4250     Document Type: Article

References (29)

1. Kuo T, Recht L. Optimizing therapy for patients with brain metastases. Semin Oncol 2006;33:299-306.
2. Withers HR. The four R's of radiotherapy. Adv Radiat Biol 1975;5:241-71.
3. Chu K, Leonhardt EA, Trinh M, et al. Computerized video time-lapse (CVTL) analysis of cell death kinetics in human bladder carcinoma cells (EJ30) X-irradiated in different phases of the cell cycle. Radiat Res 2002;158:667-77.
4. Kuerbitz SJ, Plunkett BS, Walsh WV, Kastan MB. Wildtype p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci U S A 1992;89:7491-5.
5. Scott SL, Earle JD, Gumerlock PH. Functional p53 increases prostate cancer cell survival after exposure to fractionated doses of ionizing radiation. Cancer Res 2003;63:7190-6.
6. Haas-Kogan DA, Kogan SS, Yount G, et al. p53 function influences the effect of fractionated radiotherapy on glioblastoma tumors. Int J Radiat Oncol Biol Phys 1999;43:399-403.
7. Dahlberg WK, Azzam EI, Yu Y, Little JB. Response of human tumor cells of varying radiosensitivity and radiocurability to fractionated irradiation. Cancer Res 1999;59:5365-9.
8. Chuang YY, Chen Y, Gadisetti Chandramouli VR, et al. Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells. Cancer Res 2002;62:6246-54.
9. Tsai MH, Chen X, Chandramouli GV, et al. Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells. Oncogene 2006;25:622-32.
10. Torres-Roca JF, Eschrich S, Zhao H, et al. Prediction of radiation sensitivity using a gene expression classifier. Cancer Res 2005;65:7169-76.
11. O'Connor PM, Jackman J, Bae I, et al. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res 1997;57:4285-300.
12. Chen SJ, Ning H, Ishida W, et al. The early-immediate gene EGR-1 is induced by transforming growth factor-β and mediates stimulation of collagen gene expression. J Biol Chem 2006;281:21183-97.
13. Amundson SA, Do KT, Vinikoor L, et al. Stress-specific signatures: expression profiling of p53 wild-type and -null human cells. Oncogene 2005;24:4572-9.
14. Khodarev NN, Beckett M, Labay E, Darga T, Roizman B, Weichselbaum RR. STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc Natl Acad Sci U S A 2004;101:1714-9.
15. Kita K, Sugaya S, Zhai L, et al. Involvement of LEU13 in interferon-induced refractoriness of human RSa cells to cell killing by X rays. Radiat Res 2003;160:302-8.
16. Levy DE, Darnell JEJ. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002;3:651-62.
17. Sreekumar A, Nyati MK, Varambally S, et al. Profiling of cancer cells using protein microarrays: discovery of novel radiation-regulated proteins. Cancer Res 2001;61:7585-93.
18. Clave E, Carosella ED, Gluckman E, Socie G. Radiation-enhanced expression of interferon-inducible genes in the KG1a primitive hematopoietic cell line. Leukemia 1997;11:114-9.
19. Townsend PA, Cragg MS, Davidson SM, et al. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage. J Cell Sci 2005;118:1629-39.
20. Kusmartsev S, Gabrilovich DI. STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion. J Immunol 2005;174:4880-91.
21. Akira S. Functional roles of STAT family proteins: lessons from knockout mice. Stem Cells 1999;17:138-46.
22. Klampfer L. Signal transducers and activators of transcription (STATs): novel targets of chemopreventive and chemotherapeutic drugs. Curr Cancer Drug Targets 2006;6:107-21.
23. Kolla V, Lindner DJ, Xiao W, Borden EC, Kalvakolanu DV. Modulation of interferon (IFN)-inducible gene expression by retinoic acid. Up-regulation of STAT1 protein in IFN-unresponsive cells. J Biol Chem 1996;271:10508-14.
24. Gregoire V, Ang KK, Rosier JF, et al. A phase I study of fludarabine combined with radiotherapy in patients with intermediate to locally advanced head and neck squamous cell carcinoma. Radiother Oncol 2002;63:187-93.
25. Rutka JT, Giblin JR, Hoifodt HK, et al. Establishment and characterization of a cell line from a human gliosarcoma. Cancer Res 1986;46:5893-902.
26. Fakhrai H, Dorigo O, Shawler DL, et al. Eradication of established intracranial rat gliomas by transforming growth factor β antisense gene therapy. Proc Natl Acad Sci U S A 1996;93:2909-14.
27. Sasaki A, Naganuma H, Satoh E, et al. Secretion of transforming growth factor-β1 and -β2 by malignant glioma cells. Neurol Med Chir Tokyo 1995;35:423-30.
28. Chorna I, Fedorenko O, Datsyuk L, Stoika R. Expression of mRNA coding for TGF-β and its receptors in irradiated human breast carcinoma MCF-7 cells differing in their sensitivity to doxorubicin. Exp Oncol 2005;27:156-8.
29. Blanchere M, Saunier E, Mestayer C, Broshuis M, Mowszowicz I. Alterations of expression and regulation of transforming growth factor β in human cancer prostate cell lines. J Steroid Biochem Mol Biol 2002;82:297-304.