STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 6, 2004, Pages 1714-1719

  Khodarev, Nikolai N ^a   Beckett, Michael ^a   Labay, Edwardine ^a   Darga, Thomas ^a   Roizman, Bernard ^a   Weichselbaum, Ralph R ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Acquired tumor radioresistance; HSV 1 replication in tumors; IFN signaling; Microarrays

Indexed keywords

COMPLEMENTARY DNA; DNA; INTERFERON; PROTEIN SUBUNIT; STAT1 ALPHA PROTEIN; STAT1 BETA PROTEIN; STAT1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RADIOTHERAPY; CELL CLONE; CELL LINE; CONTROLLED STUDY; DNA MICROARRAY; DNA REPLICATION; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE INDUCTION; GENETIC TRANSFECTION; HEAD AND NECK CANCER; HUMAN; HUMAN TISSUE; IN VIVO STUDY; IRRADIATION; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION PROTECTION; RADIOSENSITIVITY; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; TUMOR; TUMOR CELL; TUMOR XENOGRAFT;

ANIMALS; DNA-BINDING PROTEINS; HUMANS; MICE; MICE, NUDE; RADIATION TOLERANCE; SELECTION (GENETICS); STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED;

ANIMALIA; HUMAN HERPESVIRUS 1; MUS MUSCULUS;

EID: 1242319531     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0308102100     Document Type: Article

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