Interferon-gamma induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon-regulatory factor-1 (IRF-1)

Cancer Letters

Volumn 314, Issue 2, 2012, Pages 213-222

  Li, Peiyuan ^a,b   Du, Qiang ^a   Cao, Zongxian ^a   Guo, Zhong ^a   Evankovich, John ^a   Yan, Wei ^a   Chang, Ying ^a   Shao, Lifang ^a   Stolz, Donna Beer ^a,c   Tsung, Allan ^a   Geller, David A ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Autophagy; Cell death; Cell growth; HCC; IFN

Indexed keywords

AUTOPHAGY PROTEIN 5; BECLIN 1; GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 1; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; IRF1 PROTEIN, HUMAN; LIGHT CHAIN 3, HUMAN; MICROTUBULE ASSOCIATED PROTEIN;

APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER INHIBITION; CARCINOMA CELL; CELL ACTIVATION; CELL DEATH; CELL MATURATION; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; CELL PROLIFERATION; LIVER TUMOR; METABOLISM; PATHOLOGY; PHAGOSOME; PHYSIOLOGY; TUMOR CELL LINE;

APOPTOSIS; AUTOPHAGY; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; INTERFERON REGULATORY FACTOR-1; INTERFERON-GAMMA; LIVER NEOPLASMS; MICROTUBULE-ASSOCIATED PROTEINS; PHAGOSOMES; SIGNAL TRANSDUCTION;

EID: 84865508002     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.09.031     Document Type: Article

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