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Volumn 43, Issue 4, 2013, Pages 1111-1116

Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation

Author keywords

Cancer upregulated gene 2; Cell migration; Drug resistance; STAT1

Indexed keywords

DOXORUBICIN; JANUS KINASE 1; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; STAT1 PROTEIN;

EID: 84882377114     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2049     Document Type: Article
Times cited : (31)

References (32)
  • 1
    • 34447291385 scopus 로고    scopus 로고
    • Molecular cloning and functional analysis of a novel oncogene, cancer-upregulated gene 2 (CUG2)
    • Lee S, Gang J, Jeon SB, et al: Molecular cloning and functional analysis of a novel oncogene, cancer-upregulated gene 2 (CUG2). Biochem Biophys Res Commun 360: 633-639, 2007.
    • (2007) Biochem Biophys Res Commun , vol.360 , pp. 633-639
    • Lee, S.1    Gang, J.2    Jeon, S.B.3
  • 2
    • 67650299735 scopus 로고    scopus 로고
    • Cancer-upregulated gene 2 (CUG2), a new component of centromere complex, is required for kinetochore function
    • Kim H, Lee M, Lee S, et al: Cancer-upregulated gene 2 (CUG2), a new component of centromere complex, is required for kinetochore function. Mol Cells 27: 697-701, 2009.
    • (2009) Mol Cells , vol.27 , pp. 697-701
    • Kim, H.1    Lee, M.2    Lee, S.3
  • 3
    • 77951101674 scopus 로고    scopus 로고
    • CUG2, a novel oncogene confers reoviral replication through Ras and p38 signaling pathway
    • Park EH, Park EH, Cho IR, et al: CUG2, a novel oncogene confers reoviral replication through Ras and p38 signaling pathway. Cancer Gene Ther 17: 307-314, 2010.
    • (2010) Cancer Gene Ther , vol.17 , pp. 307-314
    • Park, E.H.1    Park, E.H.2    Cho, I.R.3
  • 4
    • 84874112788 scopus 로고    scopus 로고
    • Cancer upregulated gene 2, a novel oncogene, confers resistance to oncolytic vesicular stomatitis virus through STAT1-OASL2 signaling
    • Malilas W, Koh SS, Srisuttee R, et al: Cancer upregulated gene 2, a novel oncogene, confers resistance to oncolytic vesicular stomatitis virus through STAT1-OASL2 signaling. Cancer Gene Ther 20: 125-132, 2013.
    • (2013) Cancer Gene Ther , vol.20 , pp. 125-132
    • Malilas, W.1    Koh, S.S.2    Srisuttee, R.3
  • 5
    • 0030788405 scopus 로고    scopus 로고
    • Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis
    • Chin YE, Kitagawa M, Kuida K, Flavell RA and Fu XY: Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol Cell Biol 17: 5328-5337, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 5328-5337
    • Chin, Y.E.1    Kitagawa, M.2    Kuida, K.3    Flavell, R.A.4    Fu, X.Y.5
  • 6
    • 0030659512 scopus 로고    scopus 로고
    • Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
    • Kumar A, Commane M, Flickinger TW, Horvath CM and Stark GR: Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 278: 1630-1632, 1997.
    • (1997) Science , vol.278 , pp. 1630-1632
    • Kumar, A.1    Commane, M.2    Flickinger, T.W.3    Horvath, C.M.4    Stark, G.R.5
  • 7
    • 0029923780 scopus 로고    scopus 로고
    • Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1
    • Chin YE, Kitagawa M, Su WC, You ZH, Iwamoto Y and Fu XY: Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 272: 719-722, 1996.
    • (1996) Science , vol.272 , pp. 719-722
    • Chin, Y.E.1    Kitagawa, M.2    Su, W.C.3    You, Z.H.4    Iwamoto, Y.5    Fu, X.Y.6
  • 9
    • 0034085912 scopus 로고    scopus 로고
    • Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters
    • Stephanou A, Brar BK, Knight RA and Latchman DS: Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters. Cell Death Differ 7: 329-330, 2000.
    • (2000) Cell Death Differ , vol.7 , pp. 329-330
    • Stephanou, A.1    Brar, B.K.2    Knight, R.A.3    Latchman, D.S.4
  • 10
    • 1242319531 scopus 로고    scopus 로고
    • STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells
    • Khodarev NN, Beckett M, Labay E, Darga T, Roizman B and Weichselbaum RR: STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc Natl Acad Sci USA 101: 1714-1719, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1714-1719
    • Khodarev, N.N.1    Beckett, M.2    Labay, E.3    Darga, T.4    Roizman, B.5    Weichselbaum, R.R.6
  • 11
    • 33845384469 scopus 로고    scopus 로고
    • STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines
    • Fryknas M, Dhar S, Oberg F, et al: STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines. Int J Cancer 120: 189-195, 2007.
    • (2007) Int J Cancer , vol.120 , pp. 189-195
    • Fryknas, M.1    Dhar, S.2    Oberg, F.3
  • 12
    • 17444362227 scopus 로고    scopus 로고
    • Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells
    • Roberts D, Schick J, Conway S, et al: Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells. Br J Cancer 92: 1149-1158, 2005.
    • (2005) Br J Cancer , vol.92 , pp. 1149-1158
    • Roberts, D.1    Schick, J.2    Conway, S.3
  • 13
    • 57449088412 scopus 로고    scopus 로고
    • An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
    • Weichselbaum RR, Ishwaran H, Yoon T, et al: An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc Natl Acad Sci USA 105: 18490-18495, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 18490-18495
    • Weichselbaum, R.R.1    Ishwaran, H.2    Yoon, T.3
  • 14
    • 78651407343 scopus 로고    scopus 로고
    • Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation
    • Park HD, Lee Y, Oh YK, et al: Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation. Oncogene 30: 201-211, 2011.
    • (2011) Oncogene , vol.30 , pp. 201-211
    • Park, H.D.1    Lee, Y.2    Oh, Y.K.3
  • 15
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
    • Liang CC, Park AY and Guan JL: In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2: 329-333, 2007.
    • (2007) Nat Protoc , vol.2 , pp. 329-333
    • Liang, C.C.1    Park, A.Y.2    Guan, J.L.3
  • 16
    • 79952344515 scopus 로고    scopus 로고
    • Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation
    • Raven JF, Williams V, Wang S, et al: Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation. Cell Cycle 10: 794-804, 2011.
    • (2011) Cell Cycle , vol.10 , pp. 794-804
    • Raven, J.F.1    Williams, V.2    Wang, S.3
  • 17
    • 0032560475 scopus 로고    scopus 로고
    • Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
    • Kaplan DH, Shankaran V, Dighe AS, et al: Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci USA 95: 7556-7561, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7556-7561
    • Kaplan, D.H.1    Shankaran, V.2    Dighe, A.S.3
  • 18
    • 67650538799 scopus 로고    scopus 로고
    • Stat1 is an inhibitor of Ras-MAPK signaling and Rho small GTPase expression with implications in the transcriptional signature of Ras transformed cells
    • Wang S and Koromilas AE: Stat1 is an inhibitor of Ras-MAPK signaling and Rho small GTPase expression with implications in the transcriptional signature of Ras transformed cells. Cell Cycle 8: 2070-2079, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 2070-2079
    • Wang, S.1    Koromilas, A.E.2
  • 19
    • 58149374051 scopus 로고    scopus 로고
    • Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1
    • Wang S, Raven JF, Durbin JE and Koromilas AE: Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1. PLoS One 3: e3476, 2008.
    • (2008) PLoS One , vol.3
    • Wang, S.1    Raven, J.F.2    Durbin, J.E.3    Koromilas, A.E.4
  • 20
    • 67149111590 scopus 로고    scopus 로고
    • STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
    • Khodarev NN, Roach P, Pitroda SP, et al: STAT1 pathway mediates amplification of metastatic potential and resistance to therapy. PLoS One 4: e5821, 2009.
    • (2009) PLoS One , vol.4
    • Khodarev, N.N.1    Roach, P.2    Pitroda, S.P.3
  • 21
    • 24944521677 scopus 로고    scopus 로고
    • Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles
    • Rickardson L, Fryknas M, Dhar S, et al: Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles. Br J Cancer 93: 483-492, 2005.
    • (2005) Br J Cancer , vol.93 , pp. 483-492
    • Rickardson, L.1    Fryknas, M.2    Dhar, S.3
  • 22
    • 71049144941 scopus 로고    scopus 로고
    • STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect
    • Pitroda SP, Wakim BT, Sood RF, et al: STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect. BMC Med 7: 68, 2009.
    • (2009) BMC Med , vol.7 , pp. 68
    • Pitroda, S.P.1    Wakim, B.T.2    Sood, R.F.3
  • 23
    • 82755183631 scopus 로고    scopus 로고
    • New centromeric component CENP-W is an RNA-associated nuclear matrix protein that interacts with nucleophosmin/B23 protein
    • Chun Y, Park B, Koh W, et al: New centromeric component CENP-W is an RNA-associated nuclear matrix protein that interacts with nucleophosmin/B23 protein. J Biol Chem 286: 42758-42769, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 42758-42769
    • Chun, Y.1    Park, B.2    Koh, W.3
  • 24
    • 41349111453 scopus 로고    scopus 로고
    • The structure and functions of NPM1/Nucleophsmin/B23, a multifunctional nucleolar acidic protein
    • Okuwaki M: The structure and functions of NPM1/Nucleophsmin/B23, a multifunctional nucleolar acidic protein. J Biochem 143: 441-448, 2008.
    • (2008) J Biochem , vol.143 , pp. 441-448
    • Okuwaki, M.1
  • 26
    • 84861790681 scopus 로고    scopus 로고
    • Molecular pathways: Interferon/stat1 pathway: Role in the tumor resistance to genotoxic stress and aggressive growth
    • Khodarev NN, Roizman B and Weichselbaum RR: Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth. Clin Cancer Res 18: 3015-3021, 2012.
    • (2012) Clin Cancer Res , vol.18 , pp. 3015-3021
    • Khodarev, N.N.1    Roizman, B.2    Weichselbaum, R.R.3
  • 27
    • 84864863792 scopus 로고    scopus 로고
    • CCR5 antagonist blocks metastasis of basal breast cancer cells
    • Velasco-Velazquez M, Jiao X, De La Fuente M, et al: CCR5 antagonist blocks metastasis of basal breast cancer cells. Cancer Res 72: 3839-3850, 2012.
    • (2012) Cancer Res , vol.72 , pp. 3839-3850
    • Velasco-Velazquez, M.1    Jiao, X.2    De La Fuente, M.3
  • 28
    • 77955640339 scopus 로고    scopus 로고
    • Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model
    • Kitamura T, Fujishita T, Loetscher P, et al: Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model. Proc Natl Acad Sci USA 107: 13063-13068, 2010.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 13063-13068
    • Kitamura, T.1    Fujishita, T.2    Loetscher, P.3
  • 29
    • 84863569576 scopus 로고    scopus 로고
    • CXCL10 promotes osteolytic bone metastasis by enhancing cancer outgrowth and osteoclastogenesis
    • Lee JH, Kim HN, Kim KO, et al: CXCL10 promotes osteolytic bone metastasis by enhancing cancer outgrowth and osteoclastogenesis. Cancer Res 72: 3175-3186, 2012.
    • (2012) Cancer Res , vol.72 , pp. 3175-3186
    • Lee, J.H.1    Kim, H.N.2    Kim, K.O.3
  • 30
    • 84865619532 scopus 로고    scopus 로고
    • Type i interferon induces CX3CL1 (fractalkine) and CCL5 (RANTES) production in human pulmonary vascular endothelial cells
    • Nakano M, Fujii T, Hashimoto M, et al: Type I interferon induces CX3CL1 (fractalkine) and CCL5 (RANTES) production in human pulmonary vascular endothelial cells. Clin Exp Immunol 170: 94-100, 2012.
    • (2012) Clin Exp Immunol , vol.170 , pp. 94-100
    • Nakano, M.1    Fujii, T.2    Hashimoto, M.3
  • 31
    • 65549126031 scopus 로고    scopus 로고
    • ICSBP-mediated immune protection against BCR-ABL-induced leukemia requires the CCL6 and CCL9 chemokines
    • Nardi V, Naveiras O, Azam M and Daley GQ: ICSBP-mediated immune protection against BCR-ABL-induced leukemia requires the CCL6 and CCL9 chemokines. Blood 113: 3813-3820, 2009.
    • (2009) Blood , vol.113 , pp. 3813-3820
    • Nardi, V.1    Naveiras, O.2    Azam, M.3    Daley, G.Q.4
  • 32
    • 0027523467 scopus 로고
    • Cooperative interaction between interferon (IFN) stimulus response element and kappaB sequence motifs controls IFN gamma-and lipopolysaccharide- stimulated transcription from the murine IP-10 promoter
    • Ohmori Y and Hamilton TA: Cooperative interaction between interferon (IFN) stimulus response element and kappaB sequence motifs controls IFN gamma-and lipopolysaccharide-stimulated transcription from the murine IP-10 promoter. J Biol Chem 268: 6677-6688, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 6677-6688
    • Ohmori, Y.1    Hamilton, T.A.2


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