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Volumn 14, Issue 1, 2012, Pages

STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA6 INTEGRIN; AREG PROTEIN; CD24 ANTIGEN; CD31 ANTIGEN; CD45 ANTIGEN; CYTOKERATIN 14; CYTOKERATIN 18; CYTOKERATIN 19; CYTOKERATIN 5; CYTOKERATIN 8; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR ALPHA; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; PROGESTERONE RECEPTOR; PROTEIN; PROTEIN MYB; PROTEIN P63; STAT1 PROTEIN; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; DNA BINDING PROTEIN; ERBB2 PROTEIN, HUMAN; PROGESTERONE RECEPTOR B; RAG2 PROTEIN, MOUSE; STAT1 PROTEIN, HUMAN; STAT1 PROTEIN, MOUSE; TRANSCRIPTOME; TUMOR MARKER;

EID: 84856010212     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr3100     Document Type: Article
Times cited : (149)

References (63)
  • 1
    • 0036838070 scopus 로고    scopus 로고
    • Estrogen receptor breast cancer phenotypes in the surveillance, epidemiology, and end results database
    • 10.1023/A:1020299707510, 12408373
    • Anderson WF, Chatterjee N, Ershler WB, Brawley OW. Estrogen receptor breast cancer phenotypes in the surveillance, epidemiology, and end results database. Breast Cancer Res Treat 2002, 76:27-36. 10.1023/A:1020299707510, 12408373.
    • (2002) Breast Cancer Res Treat , vol.76 , pp. 27-36
    • Anderson, W.F.1    Chatterjee, N.2    Ershler, W.B.3    Brawley, O.W.4
  • 2
    • 0035024276 scopus 로고    scopus 로고
    • Prognostic and predictive factors in breast cancer
    • 10.1053/ctrv.2000.0207, 11417963
    • Bundred NJ. Prognostic and predictive factors in breast cancer. Cancer Treat Rev 2001, 27:137-142. 10.1053/ctrv.2000.0207, 11417963.
    • (2001) Cancer Treat Rev , vol.27 , pp. 137-142
    • Bundred, N.J.1
  • 4
    • 77956474928 scopus 로고    scopus 로고
    • Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool
    • 10.1038/sj.bjc.6605845, 2966629, 20700118
    • Chia YH, Ellis MJ, Ma CX. Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool. Br J Cancer 2010, 103:759-764. 10.1038/sj.bjc.6605845, 2966629, 20700118.
    • (2010) Br J Cancer , vol.103 , pp. 759-764
    • Chia, Y.H.1    Ellis, M.J.2    Ma, C.X.3
  • 5
    • 58049214012 scopus 로고    scopus 로고
    • A spontaneous estrogen dependent, tamoxifen sensitive mouse mammary tumor: a new model system to study hormone-responsiveness in immune competent mice
    • 10.1007/s10549-007-9888-x, 18183485
    • Simian M, Manzur T, Rodriguez V, de Kier Joffe EB, Klein S. A spontaneous estrogen dependent, tamoxifen sensitive mouse mammary tumor: a new model system to study hormone-responsiveness in immune competent mice. Breast Cancer Res Treat 2009, 113:1-8. 10.1007/s10549-007-9888-x, 18183485.
    • (2009) Breast Cancer Res Treat , vol.113 , pp. 1-8
    • Simian, M.1    Manzur, T.2    Rodriguez, V.3    de Kier Joffe, E.B.4    Klein, S.5
  • 7
    • 1242353199 scopus 로고    scopus 로고
    • Establishment of two hormone-responsive mouse mammary carcinoma cell lines derived from a metastatic mammary tumor
    • 10.1023/B:BREA.0000014044.02728.ac, 14758093
    • Efeyan A, Fabris V, Merani S, Lanari C, Molinolo AA. Establishment of two hormone-responsive mouse mammary carcinoma cell lines derived from a metastatic mammary tumor. Breast Cancer Res Treat 2004, 83:233-244. 10.1023/B:BREA.0000014044.02728.ac, 14758093.
    • (2004) Breast Cancer Res Treat , vol.83 , pp. 233-244
    • Efeyan, A.1    Fabris, V.2    Merani, S.3    Lanari, C.4    Molinolo, A.A.5
  • 8
    • 0017149786 scopus 로고
    • Hormone-dependent mammary tumors in strain GR/A mice. III. Effectiveness of supplementary hormone treatments in inducing tumorous phase growth
    • Aidells BD, Daniel CW. Hormone-dependent mammary tumors in strain GR/A mice. III. Effectiveness of supplementary hormone treatments in inducing tumorous phase growth. J Natl Cancer Inst 1976, 57:527-537.
    • (1976) J Natl Cancer Inst , vol.57 , pp. 527-537
    • Aidells, B.D.1    Daniel, C.W.2
  • 9
    • 0030889207 scopus 로고    scopus 로고
    • The IFNγ receptor: a paradigm for cytokine receptor signaling
    • 10.1146/annurev.immunol.15.1.563, 9143700
    • Bach EA, Aguet M, Schreiber RD. The IFNγ receptor: a paradigm for cytokine receptor signaling. Annu Rev Immunol 1997, 15:563-591. 10.1146/annurev.immunol.15.1.563, 9143700.
    • (1997) Annu Rev Immunol , vol.15 , pp. 563-591
    • Bach, E.A.1    Aguet, M.2    Schreiber, R.D.3
  • 11
    • 0030024563 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
    • 10.1016/S0092-8674(00)81289-1, 8608598
    • Durbin JE, Hackenmiller R, Celeste Simon M, Levy DE. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 1996, 84:443-450. 10.1016/S0092-8674(00)81289-1, 8608598.
    • (1996) Cell , vol.84 , pp. 443-450
    • Durbin, J.E.1    Hackenmiller, R.2    Celeste Simon, M.3    Levy, D.E.4
  • 12
    • 0032560475 scopus 로고    scopus 로고
    • Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice
    • 10.1073/pnas.95.13.7556, 22681, 9636188
    • Kaplan DH, Shankaran V, Dighe AS, Stockert E, Aguet M, Old LJ, Schreiber RD. Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci USA 1998, 95:7556-7561. 10.1073/pnas.95.13.7556, 22681, 9636188.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7556-7561
    • Kaplan, D.H.1    Shankaran, V.2    Dighe, A.S.3    Stockert, E.4    Aguet, M.5    Old, L.J.6    Schreiber, R.D.7
  • 13
    • 0035953308 scopus 로고    scopus 로고
    • IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • 10.1038/35074122, 11323675
    • Shankaran V, Ikeda H, Bruce AT, White JM, Swanson PE, Old LJ, Schreiber RD. IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 2001, 410:1107-1111. 10.1038/35074122, 11323675.
    • (2001) Nature , vol.410 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.T.3    White, J.M.4    Swanson, P.E.5    Old, L.J.6    Schreiber, R.D.7
  • 14
    • 33750321707 scopus 로고    scopus 로고
    • Interferons, immunity and cancer immunoediting
    • 10.1038/nri1961, 17063185
    • Dunn GP, Koebel CM, Schreiber RD. Interferons, immunity and cancer immunoediting. Nat Rev Immunol 2006, 6:836-848. 10.1038/nri1961, 17063185.
    • (2006) Nat Rev Immunol , vol.6 , pp. 836-848
    • Dunn, G.P.1    Koebel, C.M.2    Schreiber, R.D.3
  • 15
    • 0030659512 scopus 로고    scopus 로고
    • Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
    • 10.1126/science.278.5343.1630, 9374464
    • Kumar A, Commane M, Flickinger TW, Horvath CM, Stark GR. Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 1997, 278:1630-1632. 10.1126/science.278.5343.1630, 9374464.
    • (1997) Science , vol.278 , pp. 1630-1632
    • Kumar, A.1    Commane, M.2    Flickinger, T.W.3    Horvath, C.M.4    Stark, G.R.5
  • 16
    • 58149374051 scopus 로고    scopus 로고
    • Stat1 phosphorylation determines Ras oncogenicity by regulating p27kip1
    • Wang S, Raven JF, Durbin JE, Koromilas AE. Stat1 phosphorylation determines Ras oncogenicity by regulating p27kip1. PLoS One 2008, 3:e4376.
    • (2008) PLoS One , vol.3
    • Wang, S.1    Raven, J.F.2    Durbin, J.E.3    Koromilas, A.E.4
  • 17
    • 0034142230 scopus 로고    scopus 로고
    • STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-γ
    • Lee C-K, Smith E, Gimeno R, Gertner R, Levy DE. STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-γ. J Immunol 2000, 164:1286-1292.
    • (2000) J Immunol , vol.164 , pp. 1286-1292
    • Lee, C.-K.1    Smith, E.2    Gimeno, R.3    Gertner, R.4    Levy, D.E.5
  • 18
    • 0034624967 scopus 로고    scopus 로고
    • Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFNγ target genes
    • 10.1073/pnas.080469697, 25807, 10792030
    • Ouchi F, Lee SW, Ouchi M, Aaronson SA, Horvath CM. Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFNγ target genes. Proc Natl Acad Sci USA 2000, 97:5208-5213. 10.1073/pnas.080469697, 25807, 10792030.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5208-5213
    • Ouchi, F.1    Lee, S.W.2    Ouchi, M.3    Aaronson, S.A.4    Horvath, C.M.5
  • 20
    • 24644522875 scopus 로고    scopus 로고
    • The 2,5 oligoadenylate synthetase/RNaseL pathway is a novel effector of BRCA1- and interferon-gamma-mediated apoptosis
    • 10.1038/sj.onc.1208698, 15940267
    • Mullan PB, Hosey AM, Buckley NE, Quinn JE, Kennedy RD, Johnston PG, Harkin DP. The 2,5 oligoadenylate synthetase/RNaseL pathway is a novel effector of BRCA1- and interferon-gamma-mediated apoptosis. Oncogene 2005, 24:5492-5501. 10.1038/sj.onc.1208698, 15940267.
    • (2005) Oncogene , vol.24 , pp. 5492-5501
    • Mullan, P.B.1    Hosey, A.M.2    Buckley, N.E.3    Quinn, J.E.4    Kennedy, R.D.5    Johnston, P.G.6    Harkin, D.P.7
  • 21
    • 79952344515 scopus 로고    scopus 로고
    • Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation
    • 10.4161/cc.10.5.14956, 21311224
    • Raven JF, Williams V, Wang S, Tremblay ML, Muller WJ, Durbin JE, Koromilas AE. Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation. Cell Cycle 2011, 10:794-804. 10.4161/cc.10.5.14956, 21311224.
    • (2011) Cell Cycle , vol.10 , pp. 794-804
    • Raven, J.F.1    Williams, V.2    Wang, S.3    Tremblay, M.L.4    Muller, W.J.5    Durbin, J.E.6    Koromilas, A.E.7
  • 22
    • 78449258706 scopus 로고    scopus 로고
    • Loss of STAT1 from mouse mammary epithelium results in an increased Neu-induced tumor burden
    • 2978912, 21076615
    • Klover PJ, Muller WJ, Robinson GW, Pfeiffer RM, Yamaji D, Hennighausen L. Loss of STAT1 from mouse mammary epithelium results in an increased Neu-induced tumor burden. Neoplasia 2010, 12:899-905. 2978912, 21076615.
    • (2010) Neoplasia , vol.12 , pp. 899-905
    • Klover, P.J.1    Muller, W.J.2    Robinson, G.W.3    Pfeiffer, R.M.4    Yamaji, D.5    Hennighausen, L.6
  • 23
    • 1242319531 scopus 로고    scopus 로고
    • STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells
    • 10.1073/pnas.0308102100, 341831, 14755057
    • Khodarev NN, Beckett M, Labay E, Darga T, Roizman B, Weichselbaum RR. STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc Natl Acad Sci USA 2004, 101:1714-1719. 10.1073/pnas.0308102100, 341831, 14755057.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1714-1719
    • Khodarev, N.N.1    Beckett, M.2    Labay, E.3    Darga, T.4    Roizman, B.5    Weichselbaum, R.R.6
  • 24
    • 35148879113 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells
    • 10.1158/0008-5472.CAN-07-1019, 17909027
    • Khodarev NN, Minn AJ, Efimova EV, Darga TE, Labay E, Beckett M, Mauceri HJ, Roizman B, Weichselbaum RR. Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells. Cancer Res 2007, 67:9214-9220. 10.1158/0008-5472.CAN-07-1019, 17909027.
    • (2007) Cancer Res , vol.67 , pp. 9214-9220
    • Khodarev, N.N.1    Minn, A.J.2    Efimova, E.V.3    Darga, T.E.4    Labay, E.5    Beckett, M.6    Mauceri, H.J.7    Roizman, B.8    Weichselbaum, R.R.9
  • 27
    • 0032896905 scopus 로고    scopus 로고
    • Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer
    • Harvey JM, Clark GM, Osborne CK, Allred DC. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 1999, 17:1474-1481.
    • (1999) J Clin Oncol , vol.17 , pp. 1474-1481
    • Harvey, J.M.1    Clark, G.M.2    Osborne, C.K.3    Allred, D.C.4
  • 29
    • 0028801363 scopus 로고
    • Formation and resolution of double-strand break intermediates in V(D)J rearrangement
    • 10.1101/gad.9.19.2409, 7557392
    • Ramsden DA, Gellert M. Formation and resolution of double-strand break intermediates in V(D)J rearrangement. Genes Dev 1995, 9:2409-2420. 10.1101/gad.9.19.2409, 7557392.
    • (1995) Genes Dev , vol.9 , pp. 2409-2420
    • Ramsden, D.A.1    Gellert, M.2
  • 30
    • 0022485724 scopus 로고
    • Functional analysis of the glucocorticoid regulatory elements present in the mouse mammary tumor virus long terminal repeat
    • 10.1016/0022-2836(86)90008-2, 3023640
    • Kuhnel B, Buetti E, Diggelmann H. Functional analysis of the glucocorticoid regulatory elements present in the mouse mammary tumor virus long terminal repeat. J Mol Biol 1986, 190:367-378. 10.1016/0022-2836(86)90008-2, 3023640.
    • (1986) J Mol Biol , vol.190 , pp. 367-378
    • Kuhnel, B.1    Buetti, E.2    Diggelmann, H.3
  • 31
    • 33750470097 scopus 로고    scopus 로고
    • CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells
    • 10.1186/bcr1371, 1413978, 16417656
    • Sleeman KE, Kendrick H, Ashworth A, Isacke CM, Smalley MJ. CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. Breast Cancer Res 2006, 8:R7. 10.1186/bcr1371, 1413978, 16417656.
    • (2006) Breast Cancer Res , vol.8
    • Sleeman, K.E.1    Kendrick, H.2    Ashworth, A.3    Isacke, C.M.4    Smalley, M.J.5
  • 34
    • 0035793042 scopus 로고    scopus 로고
    • Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection
    • 10.1073/pnas.011404098, 14539, 11134512
    • Li C, Wong WH. Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection. Proc Natl Acad Sci USA 2001, 98:31-36. 10.1073/pnas.011404098, 14539, 11134512.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 31-36
    • Li, C.1    Wong, W.H.2
  • 35
    • 84858077248 scopus 로고    scopus 로고
    • Mouse Genome Informatics-Mammalian Orthology
    • Mouse Genome Informatics-Mammalian Orthology. , http://www.informatics.jax.org/orthology.shtml
  • 37
    • 84858075418 scopus 로고    scopus 로고
    • Distance-weighted discrimination
    • Cancer Biomedical Informatics Grid, National Cancer Institute
    • Cancer Biomedical Informatics Grid, National Cancer Institute Distance-weighted discrimination. Cancer Biomedical Informatics Grid, National Cancer Institute., https://cabig.nci.nih.gov/tools/DWD
  • 39
    • 84986532529 scopus 로고
    • Cluster analysis of molecular conformations
    • Shenkin PS, McDonald DQ. Cluster analysis of molecular conformations. J Comput Chem 1994, 15:899-916.
    • (1994) J Comput Chem , vol.15 , pp. 899-916
    • Shenkin, P.S.1    McDonald, D.Q.2
  • 40
    • 9444225935 scopus 로고    scopus 로고
    • Java Treeview-extensible visualization of microarray data
    • 10.1093/bioinformatics/bth349, 15180930
    • Saldanha AJ. Java Treeview-extensible visualization of microarray data. Bioinformatics 2004, 20:3246-3248. 10.1093/bioinformatics/bth349, 15180930.
    • (2004) Bioinformatics , vol.20 , pp. 3246-3248
    • Saldanha, A.J.1
  • 41
    • 84870532154 scopus 로고    scopus 로고
    • Gene Expression Omnibus
    • Gene Expression Omnibus. , http://www.ncbi.nlm.nih.gov/geo
  • 42
    • 54949118365 scopus 로고    scopus 로고
    • Statistical significance of clustering for high dimension low sample size data
    • Liu Y, Hayes DN, Nobel A, Marron JS. Statistical significance of clustering for high dimension low sample size data. J Am Stat Assoc 2008, 103:1281-1293.
    • (2008) J Am Stat Assoc , vol.103 , pp. 1281-1293
    • Liu, Y.1    Hayes, D.N.2    Nobel, A.3    Marron, J.S.4
  • 43
    • 0038724494 scopus 로고    scopus 로고
    • Consensus clustering: a resampling-based method for class discovery and visualization of gene expression microarray data
    • Monti S, Tamayo P, Mesirov J, Golub TR. Consensus clustering: a resampling-based method for class discovery and visualization of gene expression microarray data. Machine Learning 2003, 52:91-118.
    • (2003) Machine Learning , vol.52 , pp. 91-118
    • Monti, S.1    Tamayo, P.2    Mesirov, J.3    Golub, T.R.4
  • 44
    • 0019573144 scopus 로고
    • A distribution-free test for tumor-growth curve analyses with application to an animal tumor immunotherapy experiment
    • 10.2307/2530427, 7272422
    • Koziol JA, Maxwell DA, Fukushima M, Colmerauer ME, Pilch YH. A distribution-free test for tumor-growth curve analyses with application to an animal tumor immunotherapy experiment. Biometrics 1981, 37:383-390. 10.2307/2530427, 7272422.
    • (1981) Biometrics , vol.37 , pp. 383-390
    • Koziol, J.A.1    Maxwell, D.A.2    Fukushima, M.3    Colmerauer, M.E.4    Pilch, Y.H.5
  • 45
    • 84870486790 scopus 로고    scopus 로고
    • The Comprehensive R Archive Network: R 2.11.1
    • The Comprehensive R Archive Network: R 2.11.1. , http://cran.r-project.org
  • 47
    • 63449121643 scopus 로고    scopus 로고
    • A signature predictive of disease outcome in breast carcinomas, identified by quantitative immunocytochemical assays
    • 10.1002/ijc.24177, 19142869
    • Charpin C, Secq V, Giusiano S, Carpentier S, Andrac L, Lavaut MN, Allasia C, Bonnier P, Garcia S. A signature predictive of disease outcome in breast carcinomas, identified by quantitative immunocytochemical assays. Int J Cancer 2009, 124:2124-2134. 10.1002/ijc.24177, 19142869.
    • (2009) Int J Cancer , vol.124 , pp. 2124-2134
    • Charpin, C.1    Secq, V.2    Giusiano, S.3    Carpentier, S.4    Andrac, L.5    Lavaut, M.N.6    Allasia, C.7    Bonnier, P.8    Garcia, S.9
  • 51
    • 33745459327 scopus 로고    scopus 로고
    • Hormones, receptors, and growth in hyperplastic enlarged lobular units: early potential precursors of breast cancer
    • 1413990, 16417654
    • Lee S, Mohsin SK, Mao S, Hilsenbeck SG, Medina D, Allred DC. Hormones, receptors, and growth in hyperplastic enlarged lobular units: early potential precursors of breast cancer. Breast Cancer Res 2005, 8:R6. 1413990, 16417654.
    • (2005) Breast Cancer Res , vol.8
    • Lee, S.1    Mohsin, S.K.2    Mao, S.3    Hilsenbeck, S.G.4    Medina, D.5    Allred, D.C.6
  • 52
    • 0035748186 scopus 로고    scopus 로고
    • Ovarian ablation as adjuvant therapy for breast cancer
    • Davidson NE. Ovarian ablation as adjuvant therapy for breast cancer. J Natl Cancer Inst Monogr 2001, 30:67-71.
    • (2001) J Natl Cancer Inst Monogr , vol.30 , pp. 67-71
    • Davidson, N.E.1
  • 53
    • 0036731485 scopus 로고    scopus 로고
    • STATs: Transcriptional control and biological impact
    • Levy DE, Darnell JE. STATs: Transcriptional control and biological impact. Rev Cell Biol 2002, 3:651-662.
    • (2002) Rev Cell Biol , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell, J.E.2
  • 54
    • 0141953896 scopus 로고    scopus 로고
    • The quest for a tumor suppressor gene phenotype
    • 10.2174/1566524033479500, 14601636
    • Presneau N, Manderson EN, Tonin PN. The quest for a tumor suppressor gene phenotype. Curr Mol Med 2003, 3:605-629. 10.2174/1566524033479500, 14601636.
    • (2003) Curr Mol Med , vol.3 , pp. 605-629
    • Presneau, N.1    Manderson, E.N.2    Tonin, P.N.3
  • 55
    • 0346792731 scopus 로고    scopus 로고
    • Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFNγ-dependent innate immunity
    • 10.1016/S1074-7613(03)00322-4, 14670297
    • Varinou L, Ramsauer K, Karaghiosoff M, Kolbe T, Pfeffer K, Muller M, Decker T. Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFNγ-dependent innate immunity. Immunity 2003, 19:793-802. 10.1016/S1074-7613(03)00322-4, 14670297.
    • (2003) Immunity , vol.19 , pp. 793-802
    • Varinou, L.1    Ramsauer, K.2    Karaghiosoff, M.3    Kolbe, T.4    Pfeffer, K.5    Muller, M.6    Decker, T.7
  • 57
    • 73949121977 scopus 로고    scopus 로고
    • Global methylation pattern of genes in androgen-sensitive and androgen-independent prostate cancer cells
    • Mishra DK, Chen Z, Wu Y, Sarkissyan M, Koeffler HP, Vadgama JV. Global methylation pattern of genes in androgen-sensitive and androgen-independent prostate cancer cells. Mol Cancer Ther 9:33-45.
    • Mol Cancer Ther , vol.9 , pp. 33-45
    • Mishra, D.K.1    Chen, Z.2    Wu, Y.3    Sarkissyan, M.4    Koeffler, H.P.5    Vadgama, J.V.6
  • 59
    • 0032127465 scopus 로고    scopus 로고
    • Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation
    • 10.1093/emboj/17.13.3660, 1170702, 9649436
    • Kovarik P, Stoiber D, Novy M, Decker T. Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation. Embo J 1998, 17:3660-3668. 10.1093/emboj/17.13.3660, 1170702, 9649436.
    • (1998) Embo J , vol.17 , pp. 3660-3668
    • Kovarik, P.1    Stoiber, D.2    Novy, M.3    Decker, T.4
  • 60
    • 0035862950 scopus 로고    scopus 로고
    • Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression
    • 10.1093/emboj/20.1.91, 140204, 11226159
    • Kovarik P, Mangold M, Ramsauer K, Heidari H, Steinborn R, Zotter A, Levy DE, Muller M, Decker T. Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression. Embo J 2001, 20:91-100. 10.1093/emboj/20.1.91, 140204, 11226159.
    • (2001) Embo J , vol.20 , pp. 91-100
    • Kovarik, P.1    Mangold, M.2    Ramsauer, K.3    Heidari, H.4    Steinborn, R.5    Zotter, A.6    Levy, D.E.7    Muller, M.8    Decker, T.9
  • 61
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
    • EBCTCG
    • EBCTCG Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005, 365:1687-1717. EBCTCG.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 62
    • 64349115050 scopus 로고    scopus 로고
    • Endocrine therapy for the treatment of postmenopausal women with breast cancer
    • 10.1586/14737140.9.2.187, 19192957
    • Harichand-Herdt S, Zelnak A, O'Regan R. Endocrine therapy for the treatment of postmenopausal women with breast cancer. Expert Rev Anticancer Ther 2009, 9:187-198. 10.1586/14737140.9.2.187, 19192957.
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 187-198
    • Harichand-Herdt, S.1    Zelnak, A.2    O'Regan, R.3
  • 63
    • 85181122894 scopus 로고    scopus 로고
    • Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials
    • 3163848, 21802721
    • Davies C, Godwin J, Gray R, Clarke M, Cutter D, Darby S, McGale P, Pan HC, Taylor C, Wang YC, Dowsett M, Ingle J, Peto R. Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials. Lancet 2011, 378:771-784. 3163848, 21802721.
    • (2011) Lancet , vol.378 , pp. 771-784
    • Davies, C.1    Godwin, J.2    Gray, R.3    Clarke, M.4    Cutter, D.5    Darby, S.6    McGale, P.7    Pan, H.C.8    Taylor, C.9    Wang, Y.C.10    Dowsett, M.11    Ingle, J.12    Peto, R.13


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.