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Volumn 84, Issue 6, 2008, Pages 1604-1612

Novel function of STAT1β in B cells: Induction of cell death by a mechanism different from that of STAT1α

Author keywords

B lymphocytes; Fludarabine; p53

Indexed keywords

PROTEIN P53; PROTEIN STAT1 ALPHA; PROTEIN STAT1 BETA; STAT1 PROTEIN; UNCLASSIFIED DRUG; ISOPROTEIN; MESSENGER RNA; NERVE GROWTH FACTOR RECEPTOR; NERVE PROTEIN; NGFR PROTEIN, HUMAN; STAT1 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN;

EID: 57149091187     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0508287     Document Type: Article
Times cited : (16)

References (45)
  • 1
    • 0030024563 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
    • Durbin, J. E., Hackenmiller, R., Simon, M. C., Levy, D. E. (1996) Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84, 443-450.
    • (1996) Cell , vol.84 , pp. 443-450
    • Durbin, J.E.1    Hackenmiller, R.2    Simon, M.C.3    Levy, D.E.4
  • 4
    • 0034142230 scopus 로고    scopus 로고
    • STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-γ
    • Lee, C. K., Smith, E., Gimeno, R., Gertner, R., Levy, D. E. (2000) STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-γ. J. Immunol. 164, 1286-1292.
    • (2000) J. Immunol , vol.164 , pp. 1286-1292
    • Lee, C.K.1    Smith, E.2    Gimeno, R.3    Gertner, R.4    Levy, D.E.5
  • 5
    • 0032473555 scopus 로고    scopus 로고
    • Human cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway
    • Miller, D. M., Rahill, B. M., Boss, J. M., Lairmore, M. D., Durbin, J. E., Waldman, J. W., Sedmak, D. D. (1998) Human cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway. J. Exp. Med. 187, 675-683.
    • (1998) J. Exp. Med , vol.187 , pp. 675-683
    • Miller, D.M.1    Rahill, B.M.2    Boss, J.M.3    Lairmore, M.D.4    Durbin, J.E.5    Waldman, J.W.6    Sedmak, D.D.7
  • 6
    • 0034657336 scopus 로고    scopus 로고
    • The role of STATs in transcriptional control and their impact on cellular function
    • Bromberg, J., Darnell Jr., J. E. (2000) The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19, 2468-2473.
    • (2000) Oncogene , vol.19 , pp. 2468-2473
    • Bromberg, J.1    Darnell Jr., J.E.2
  • 7
    • 0034624967 scopus 로고    scopus 로고
    • Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-γ target genes
    • Ouchi, T., Lee, S. W., Ouchi, M., Aaronson, S. A., Horvath, C. M. (2000) Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-γ target genes. Proc. Natl. Acad. Sci. USA 97, 5208-5213.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5208-5213
    • Ouchi, T.1    Lee, S.W.2    Ouchi, M.3    Aaronson, S.A.4    Horvath, C.M.5
  • 8
    • 1042301419 scopus 로고    scopus 로고
    • STAT1-induced apoptosis is mediated by caspases 2, 3, and 7
    • Sironi, J. J., Ouchi, T. (2004) STAT1-induced apoptosis is mediated by caspases 2, 3, and 7. J. Biol. Chem. 279, 4066-4074.
    • (2004) J. Biol. Chem , vol.279 , pp. 4066-4074
    • Sironi, J.J.1    Ouchi, T.2
  • 9
    • 33745845126 scopus 로고    scopus 로고
    • Autophagy contributes to caspase-independent macrophage cell death
    • Xu, Y., Kim, S. O., Li, Y., Han, J. (2006) Autophagy contributes to caspase-independent macrophage cell death. J. Biol. Chem. 281, 19179-19187.
    • (2006) J. Biol. Chem , vol.281 , pp. 19179-19187
    • Xu, Y.1    Kim, S.O.2    Li, Y.3    Han, J.4
  • 10
    • 22544482621 scopus 로고    scopus 로고
    • Essential role of STAT1 in caspasein-dependent cell death of activated macrophages through the p38 mitogen-activated protein kinase/STAT1/reactive oxygen species pathway
    • Kim, H. S., Lee, M. S. (2005) Essential role of STAT1 in caspasein-dependent cell death of activated macrophages through the p38 mitogen-activated protein kinase/STAT1/reactive oxygen species pathway. Mol. Cell. Biol. 25, 6821-6833.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 6821-6833
    • Kim, H.S.1    Lee, M.S.2
  • 11
    • 0032401780 scopus 로고    scopus 로고
    • Ser727-dependent recruitment of MCM5 by Stat1α in IFN-γ-induced transcriptional activation
    • Zhang, J. J., Zhao, Y., Chait, B. T., Lathem, W. W., Ritzi, M., Knippers, R., Darnell Jr., J. E. (1998) Ser727-dependent recruitment of MCM5 by Stat1α in IFN-γ-induced transcriptional activation. EMBO J. 17, 6963-6971.
    • (1998) EMBO J , vol.17 , pp. 6963-6971
    • Zhang, J.J.1    Zhao, Y.2    Chait, B.T.3    Lathem, W.W.4    Ritzi, M.5    Knippers, R.6    Darnell Jr., J.E.7
  • 12
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen, Z., Zhong, Z., Darnell Jr., J. E. (1995) Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82, 241-250.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 13
    • 0029903770 scopus 로고    scopus 로고
    • DNA binding of in vitro activated Stat1 α, Stat1 β and truncated Stat1: Interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites
    • Vinkemeier, U., Cohen, S. L., Moarefi, I., Chait, B. T., Kuriyan, J., Darnell Jr., J. E. (1996) DNA binding of in vitro activated Stat1 α, Stat1 β and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites. EMBO J. 15, 5616-5626.
    • (1996) EMBO J , vol.15 , pp. 5616-5626
    • Vinkemeier, U.1    Cohen, S.L.2    Moarefi, I.3    Chait, B.T.4    Kuriyan, J.5    Darnell Jr., J.E.6
  • 14
    • 0142085085 scopus 로고    scopus 로고
    • Distinct transcriptional activation functions of STAT1α and STAT1β on DNA and chromatin templates
    • Zakharova, N., Lymar, E. S., Yang, E., Malik, S., Zhang, J. J., Roeder, R. G., Darnell Jr., J. E. (2003) Distinct transcriptional activation functions of STAT1α and STAT1β on DNA and chromatin templates. J. Biol. Chem. 278, 43067-43073.
    • (2003) J. Biol. Chem , vol.278 , pp. 43067-43073
    • Zakharova, N.1    Lymar, E.S.2    Yang, E.3    Malik, S.4    Zhang, J.J.5    Roeder, R.G.6    Darnell Jr., J.E.7
  • 16
    • 0347627715 scopus 로고    scopus 로고
    • Mycobacterium avium inhibition of IFN-γ signaling in mouse macrophages: Toll-like receptor 2 stimulation increases expression of dominant-negative STAT1 β by mRNA stabilization
    • Alvarez, G. R., Zwilling, B. S., Lafuse, W. P. (2003) Mycobacterium avium inhibition of IFN-γ signaling in mouse macrophages: Toll-like receptor 2 stimulation increases expression of dominant-negative STAT1 β by mRNA stabilization. J. Immunol. 171, 6766-6773.
    • (2003) J. Immunol , vol.171 , pp. 6766-6773
    • Alvarez, G.R.1    Zwilling, B.S.2    Lafuse, W.P.3
  • 17
    • 21644436805 scopus 로고    scopus 로고
    • Leishmania inhibits STAT1-mediated IFN-γ signaling in macrophages: Increased tyrosine phosphorylation of dominant negative STAT1β by Leishmania mexicana
    • Bhardwaj, N., Rosas, L. E., Lafuse, W. P., Satoskar, A. R. (2005) Leishmania inhibits STAT1-mediated IFN-γ signaling in macrophages: increased tyrosine phosphorylation of dominant negative STAT1β by Leishmania mexicana. Int. J. Parasitol. 35, 75-82.
    • (2005) Int. J. Parasitol , vol.35 , pp. 75-82
    • Bhardwaj, N.1    Rosas, L.E.2    Lafuse, W.P.3    Satoskar, A.R.4
  • 19
    • 0344120757 scopus 로고    scopus 로고
    • Molecular characterization and IFN signal pathway analysis of Carassius auratus CaSTAT1 identified from the cultured cells in response to virus infection
    • Zhang, Y., Gui, J. (2004) Molecular characterization and IFN signal pathway analysis of Carassius auratus CaSTAT1 identified from the cultured cells in response to virus infection. Dev. Comp. Immunol. 28, 211-227.
    • (2004) Dev. Comp. Immunol , vol.28 , pp. 211-227
    • Zhang, Y.1    Gui, J.2
  • 20
    • 0025777811 scopus 로고
    • Action of 9-β-D-arabinofuranosyl-2- fluoroadenine on RNA metabolism
    • Huang, P., Plunkett, W. (1991) Action of 9-β-D-arabinofuranosyl-2- fluoroadenine on RNA metabolism. Mol. Pharmacol. 39, 449-455.
    • (1991) Mol. Pharmacol , vol.39 , pp. 449-455
    • Huang, P.1    Plunkett, W.2
  • 21
    • 0042024916 scopus 로고    scopus 로고
    • Activation of a p53-mediated apoptotic pathway in quiescent lymphocytes after the inhibition of DNA repair by fludarabine
    • Rao, V. A., Plunkett, W. (2003) Activation of a p53-mediated apoptotic pathway in quiescent lymphocytes after the inhibition of DNA repair by fludarabine. Clin. Cancer Res. 9, 3204-3212.
    • (2003) Clin. Cancer Res , vol.9 , pp. 3204-3212
    • Rao, V.A.1    Plunkett, W.2
  • 22
    • 0023187987 scopus 로고
    • Phase II trial of 9-β-D-arabinofuranosyl-2- fluoroadenine 5′-monophosphate in non-Hodgkin's lymphoma: Prospective comparison of response with deoxycytidine kinase activity
    • Leiby, J. M., Snider, K. M., Kraut, E. H., Metz, E. N., Malspeis, L., Grever, M. R. (1987) Phase II trial of 9-β-D-arabinofuranosyl-2- fluoroadenine 5′-monophosphate in non-Hodgkin's lymphoma: prospective comparison of response with deoxycytidine kinase activity. Cancer Res. 47, 2719-2722.
    • (1987) Cancer Res , vol.47 , pp. 2719-2722
    • Leiby, J.M.1    Snider, K.M.2    Kraut, E.H.3    Metz, E.N.4    Malspeis, L.5    Grever, M.R.6
  • 23
    • 0023918456 scopus 로고
    • Phase I clinical investigation of fludarabine phosphate by a loading-dose and continuous-infusion schedule
    • Leiby, J. M., Grever, M. R., Staubus, A. E., Neidhart, J. A., Malspeis, L. (1988) Phase I clinical investigation of fludarabine phosphate by a loading-dose and continuous-infusion schedule. J. Natl. Cancer Inst. 80, 447-449.
    • (1988) J. Natl. Cancer Inst , vol.80 , pp. 447-449
    • Leiby, J.M.1    Grever, M.R.2    Staubus, A.E.3    Neidhart, J.A.4    Malspeis, L.5
  • 26
    • 0028172868 scopus 로고
    • p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
    • Wattel, E., Preudhomme, C., Hecquet, B., Vanrumbeke, M., Quesnel, B., Dervite, I., Morel, P., Fenaux, P. (1994) p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood 84, 3148-3157.
    • (1994) Blood , vol.84 , pp. 3148-3157
    • Wattel, E.1    Preudhomme, C.2    Hecquet, B.3    Vanrumbeke, M.4    Quesnel, B.5    Dervite, I.6    Morel, P.7    Fenaux, P.8
  • 27
    • 0034200867 scopus 로고    scopus 로고
    • Role of p53 in cellular response to anticancer nucleoside analog-induced DNA damage
    • Feng, L., Achanta, G., Pelicano, H., Zhang, W., Plunkett, W., Huang, P. (2000) Role of p53 in cellular response to anticancer nucleoside analog-induced DNA damage. Int. J. Mol. Med. 5, 597-604.
    • (2000) Int. J. Mol. Med , vol.5 , pp. 597-604
    • Feng, L.1    Achanta, G.2    Pelicano, H.3    Zhang, W.4    Plunkett, W.5    Huang, P.6
  • 34
    • 0025830873 scopus 로고
    • J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential
    • Reers, M., Smith, T. W., Chen, L. B. (1991) J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential. Biochemistry 30, 4480-4486.
    • (1991) Biochemistry , vol.30 , pp. 4480-4486
    • Reers, M.1    Smith, T.W.2    Chen, L.B.3
  • 36
    • 0036678012 scopus 로고    scopus 로고
    • Constitutive activation of Jak/STAT proteins in Epstein-Barr virus-infected B-cell lines from patients with posttransplant lymphoproliferative disorder
    • Nepomuceno, R. R., Snow, A. L., Robert Beatty, P., Krams, S. M., Martinez, O. M. (2002) Constitutive activation of Jak/STAT proteins in Epstein-Barr virus-infected B-cell lines from patients with posttransplant lymphoproliferative disorder. Transplantation 74, 396-402.
    • (2002) Transplantation , vol.74 , pp. 396-402
    • Nepomuceno, R.R.1    Snow, A.L.2    Robert Beatty, P.3    Krams, S.M.4    Martinez, O.M.5
  • 38
    • 0037643491 scopus 로고    scopus 로고
    • The TP53 dependence of radiation-induced chromosome instability in human lymphoblastoid cells
    • Schwartz, J. L., Jordan, R., Evans, H. H., Lenarczyk, M., Liber, H. (2003) The TP53 dependence of radiation-induced chromosome instability in human lymphoblastoid cells. Radiat. Res. 159, 730-736.
    • (2003) Radiat. Res , vol.159 , pp. 730-736
    • Schwartz, J.L.1    Jordan, R.2    Evans, H.H.3    Lenarczyk, M.4    Liber, H.5
  • 39
    • 21144435503 scopus 로고    scopus 로고
    • A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival
    • Alvi, A. J., Austen, B., Weston, V. J., Fegan, C., MacCallum, D., Gianella-Borradori, A., Lane, D. P., Hubank, M., Powell, J. E., Wei, W., Taylor, A. M., Moss, P. A., Stankovic, T. (2005) A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival. Blood 105, 4484-4491.
    • (2005) Blood , vol.105 , pp. 4484-4491
    • Alvi, A.J.1    Austen, B.2    Weston, V.J.3    Fegan, C.4    MacCallum, D.5    Gianella-Borradori, A.6    Lane, D.P.7    Hubank, M.8    Powell, J.E.9    Wei, W.10    Taylor, A.M.11    Moss, P.A.12    Stankovic, T.13
  • 42
    • 33645787761 scopus 로고    scopus 로고
    • Human complete Stat-1 deficiency is associated with defective type I and II IFN responses in vitro but immunity to some low virulence viruses in vivo
    • Chapgier, A., Wynn, R. F., Jouanguy, E., Filipe-Santos, O., Zhang, S., Feinberg, J., Hawkins, K., Casanova, J. L., Arkwright, P. D. (2006) Human complete Stat-1 deficiency is associated with defective type I and II IFN responses in vitro but immunity to some low virulence viruses in vivo. J. Immunol. 176, 5078-5083.
    • (2006) J. Immunol , vol.176 , pp. 5078-5083
    • Chapgier, A.1    Wynn, R.F.2    Jouanguy, E.3    Filipe-Santos, O.4    Zhang, S.5    Feinberg, J.6    Hawkins, K.7    Casanova, J.L.8    Arkwright, P.D.9
  • 43
    • 0031308702 scopus 로고    scopus 로고
    • IL-4-induced STAT6 suppresses IFN-γ-stimulated STAT1-dependent transcription in mouse macrophages
    • Ohmori, Y., Hamilton, T. A. (1997) IL-4-induced STAT6 suppresses IFN-γ-stimulated STAT1-dependent transcription in mouse macrophages. J. Immunol. 159, 5474-5482.
    • (1997) J. Immunol , vol.159 , pp. 5474-5482
    • Ohmori, Y.1    Hamilton, T.A.2
  • 45
    • 0036152672 scopus 로고    scopus 로고
    • Roles of Stat1, Stat2, and interferon regulatory factor-9 (IRF-9) in interferon τ regulation of IRF-1
    • Stewart, M. D., Choi, Y., Johnson, G. A., Yu-Lee, L. Y., Bazer, F. W., Spencer, T. E. (2002) Roles of Stat1, Stat2, and interferon regulatory factor-9 (IRF-9) in interferon τ regulation of IRF-1. Biol. Reprod. 66, 393-400.
    • (2002) Biol. Reprod , vol.66 , pp. 393-400
    • Stewart, M.D.1    Choi, Y.2    Johnson, G.A.3    Yu-Lee, L.Y.4    Bazer, F.W.5    Spencer, T.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.