메뉴 건너뛰기




Volumn 208, Issue 10, 2011, Pages 2005-2016

Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ALPHA INTERFERON RECEPTOR; B7 ANTIGEN; BETA INTERFERON; BETA INTERFERON RECEPTOR; CD40 ANTIGEN; CD86 ANTIGEN; CD8ALPHA ANTIGEN; GLYCOPROTEIN P 15095; INTERFERON; STAT1 PROTEIN;

EID: 80355136945     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20101159     Document Type: Article
Times cited : (936)

References (56)
  • 1
    • 33846506812 scopus 로고    scopus 로고
    • Tolerization of tumor-specific T cells despite efficient initial priming in a primary murine model of prostate cancer
    • Anderson, M.J., K. Shafer-Weaver, N.M. Greenberg, and A.A. Hurwitz. 2007. Tolerization of tumor-specific T cells despite efficient initial priming in a primary murine model of prostate cancer. J. Immunol. 178:1268-1276.
    • (2007) J. Immunol. , vol.178 , pp. 1268-1276
    • Anderson, M.J.1    Shafer-Weaver, K.2    Greenberg, N.M.3    Hurwitz, A.A.4
  • 2
    • 0032844479 scopus 로고    scopus 로고
    • An expanded peripheral T cell population to a cytotoxic T lymphocyte (CTL)-defined, melanocyte-specific antigen in metastatic melanoma patients impacts on generation of peptide-specific CTLs but does not overcome tumor escape from immune surveillance in metastatic lesions
    • Anichini, A., A. Molla, R. Mortarini, G. Tragni, I. Bersani, M. Di Nicola, A.M. Gianni, S. Pilotti, R. Dunbar, V. Cerundolo, and G. Parmiani. 1999. An expanded peripheral T cell population to a cytotoxic T lymphocyte (CTL)-defined, melanocyte-specific antigen in metastatic melanoma patients impacts on generation of peptide-specific CTLs but does not overcome tumor escape from immune surveillance in metastatic lesions. J. Exp. Med. 190:651-667. http://dx.doi.org/10.1084/jem.190.5.651
    • (1999) J. Exp. Med. , vol.190 , pp. 651-667
    • Anichini, A.1    Molla, A.2    Mortarini, R.3    Tragni, G.4    Bersani, I.5    Di Nicola, M.6    Gianni, A.M.7    Pilotti, S.8    Dunbar, R.9    Cerundolo, V.10    Parmiani, G.11
  • 4
    • 0033747044 scopus 로고    scopus 로고
    • Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway
    • Basu, S., R.J. Binder, R. Suto, K.M. Anderson, and P.K. Srivastava. 2000. Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway. Int. Immunol. 12:1539-1546. http://dx.doi.org/10.1093/intimm/12.11.1539
    • (2000) Int. Immunol. , vol.12 , pp. 1539-1546
    • Basu, S.1    Binder, R.J.2    Suto, R.3    Anderson, K.M.4    Srivastava, P.K.5
  • 5
    • 0842300368 scopus 로고    scopus 로고
    • Cutting edge: conventional CD8 alpha+ dendritic cells are generally involved in priming CTL immunity to viruses
    • Belz, G.T., C.M. Smith, D. Eichner, K. Shortman, G. Karupiah, F.R. Carbone, and W.R. Heath. 2004. Cutting edge: conventional CD8 alpha+ dendritic cells are generally involved in priming CTL immunity to viruses. J. Immunol. 172:1996-2000.
    • (2004) J. Immunol. , vol.172 , pp. 1996-2000
    • Belz, G.T.1    Smith, C.M.2    Eichner, D.3    Shortman, K.4    Karupiah, G.5    Carbone, F.R.6    Heath, W.R.7
  • 6
    • 33646418683 scopus 로고    scopus 로고
    • Combinational FLt3 ligand and granulocyte macrophage colonystimulating factor treatment promotes enhanced tumor infiltration by dendritic cells and antitumor CD8(+) T-cell cross-priming but is ineffective as a therapy
    • Berhanu, A., J. Huang, S.M. Alber, S.C. Watkins, and W.J. Storkus. 2006. Combinational FLt3 ligand and granulocyte macrophage colonystimulating factor treatment promotes enhanced tumor infiltration by dendritic cells and antitumor CD8(+) T-cell cross-priming but is ineffective as a therapy. Cancer Res. 66:4895-4903. http://dx.doi.org/10.1158/0008-5472.CAN-05-2384
    • (2006) Cancer Res , vol.66 , pp. 4895-4903
    • Berhanu, A.1    Huang, J.2    Alber, S.M.3    Watkins, S.C.4    Storkus, W.J.5
  • 7
    • 0030656556 scopus 로고    scopus 로고
    • Cancer Tumor antigens
    • Boon, T., and L.J. Old. 1997. Cancer Tumor antigens. Curr. Opin. Immunol. 9:681-683. http://dx.doi.org/10.1016/S0952-7915(97)80049-0
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 681-683
    • Boon, T.1    Old, L.J.2
  • 8
    • 70449518424 scopus 로고    scopus 로고
    • Selective expression of the chemokine receptor XCR1 on cross-presenting dendritic cells determines cooperation with CD8+ T cells
    • Dorner, B.G., M.B. Dorner, X. Zhou, C. Opitz, A. Mora, S. Güttler, A. Hutloff, H.W. Mages, K. Ranke, M. Schaefer, et al. 2009. Selective expression of the chemokine receptor XCR1 on cross-presenting dendritic cells determines cooperation with CD8+ T cells. Immunity. 31:823-833. http://dx.doi.org/10.1016/j.immuni.2009.08.027
    • (2009) Immunity , vol.31 , pp. 823-833
    • Dorner, B.G.1    Dorner, M.B.2    Zhou, X.3    Opitz, C.4    Mora, A.5    Güttler, S.6    Hutloff, A.7    Mages, H.W.8    Ranke, K.9    Schaefer, M.10
  • 10
    • 33750321707 scopus 로고    scopus 로고
    • Interferons, immunity and cancer immunoediting
    • Dunn, G.P., C.M. Koebel, and R.D. Schreiber. 2006. Interferons, immunity and cancer immunoediting. Nat. Rev. Immunol. 6:836-848. http://dx.doi.org/10.1038/nri1961
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 836-848
    • Dunn, G.P.1    Koebel, C.M.2    Schreiber, R.D.3
  • 11
    • 0030051657 scopus 로고    scopus 로고
    • Endogenous IL-12 is necessary for rejection of P815 tumor variants in vivo
    • Fallarino, F., C. Uyttenhove, T. Boon, and T.F. Gajewski. 1996. Endogenous IL-12 is necessary for rejection of P815 tumor variants in vivo. J. Immunol. 156:1095-1100.
    • (1996) J. Immunol. , vol.156 , pp. 1095-1100
    • Fallarino, F.1    Uyttenhove, C.2    Boon, T.3    Gajewski, T.F.4
  • 13
    • 0029009835 scopus 로고
    • Costimulation with B7-1, IL-6, and IL-12 is sufficient for primary generation of murine antitumor cytolytic T lymphocytes in vitro
    • Gajewski, T.F., J.C. Renauld, A. Van Pel, and T. Boon. 1995. Costimulation with B7-1, IL-6, and IL-12 is sufficient for primary generation of murine antitumor cytolytic T lymphocytes in vitro. J. Immunol. 154: 5637-5648.
    • (1995) J. Immunol. , vol.154 , pp. 5637-5648
    • Gajewski, T.F.1    Renauld, J.C.2    Van Pel, A.3    Boon, T.4
  • 15
    • 0021070204 scopus 로고
    • Injection of mice with antibody to interferon enhances the growth of transplantable murine tumors
    • Gresser, I., F. Belardelli, C. Maury, M.T. Maunoury, and M.G. Tovey. 1983. Injection of mice with antibody to interferon enhances the growth of transplantable murine tumors. J. Exp. Med. 158:2095-2107. http://dx.doi.org/10.1084/jem.158.6.2095
    • (1983) J. Exp. Med. , vol.158 , pp. 2095-2107
    • Gresser, I.1    Belardelli, F.2    Maury, C.3    Maunoury, M.T.4    Tovey, M.G.5
  • 17
    • 33745632047 scopus 로고    scopus 로고
    • Tumor progression despite massive influx of activated CD8(+) T cells in a patient with malignant melanoma ascites
    • Harlin, H., T.V. Kuna, A.C. Peterson, Y. Meng, and T.F. Gajewski. 2006. Tumor progression despite massive influx of activated CD8(+) T cells in a patient with malignant melanoma ascites. Cancer Immunol. Immunother. 55:1185-1197. http://dx.doi.org/10.1007/s00262-005-0118-2
    • (2006) Cancer Immunol. Immunother. , vol.55 , pp. 1185-1197
    • Harlin, H.1    Kuna, T.V.2    Peterson, A.C.3    Meng, Y.4    Gajewski, T.F.5
  • 18
    • 66149156276 scopus 로고    scopus 로고
    • Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment
    • Harlin, H., Y. Meng, A.C. Peterson, Y. Zha, M. Tretiakova, C. Slingluff, M. McKee, and T.F. Gajewski. 2009. Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment. Cancer Res. 69:3077-3085. http://dx.doi.org/10.1158/0008-5472.CAN-08-2281
    • (2009) Cancer Res , vol.69 , pp. 3077-3085
    • Harlin, H.1    Meng, Y.2    Peterson, A.C.3    Zha, Y.4    Tretiakova, M.5    Slingluff, C.6    McKee, M.7    Gajewski, T.F.8
  • 20
    • 0037234768 scopus 로고    scopus 로고
    • TCRs with high affinity for foreign pMHC show self-reactivity
    • Holler, P.D., L.K. Chlewicki, and D.M. Kranz. 2003. TCRs with high affinity for foreign pMHC show self-reactivity. Nat. Immunol. 4:55-62. http://dx.doi.org/10.1038/ni863
    • (2003) Nat. Immunol. , vol.4 , pp. 55-62
    • Holler, P.D.1    Chlewicki, L.K.2    Kranz, D.M.3
  • 21
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
    • Huang, A.Y., P. Golumbek, M. Ahmadzadeh, E. Jaffee, D. Pardoll, and H. Levitsky. 1994. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science. 264:961-965. http://dx.doi.org/10.1126/science.7513904
    • (1994) Science , vol.264 , pp. 961-965
    • Huang, A.Y.1    Golumbek, P.2    Ahmadzadeh, M.3    Jaffee, E.4    Pardoll, D.5    Levitsky, H.6
  • 22
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
    • Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R.M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176:1693-1702. http://dx.doi.org/10.1084/jem.176.6.1693
    • (1992) J. Exp. Med. , vol.176 , pp. 1693-1702
    • Inaba, K.1    Inaba, M.2    Romani, N.3    Aya, H.4    Deguchi, M.5    Ikehara, S.6    Muramatsu, S.7    Steinman, R.M.8
  • 24
    • 70349943834 scopus 로고    scopus 로고
    • STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
    • Ishikawa, H., Z. Ma, and G.N. Barber. 2009. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature. 461:788-792. http://dx.doi.org/10.1038/nature08476
    • (2009) Nature , vol.461 , pp. 788-792
    • Ishikawa, H.1    Ma, Z.2    Barber, G.N.3
  • 25
    • 18644375874 scopus 로고    scopus 로고
    • In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens
    • Jung, S., D. Unutmaz, P. Wong, G. Sano, K. De los Santos, T. Sparwasser, S. Wu, S. Vuthoori, K. Ko, F. Zavala, et al. 2002. In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity. 17:211-220. http://dx.doi.org/10.1016/S1074-7613(02)00365-5
    • (2002) Immunity , vol.17 , pp. 211-220
    • Jung, S.1    Unutmaz, D.2    Wong, P.3    Sano, G.4    De los Santos, K.5    Sparwasser, T.6    Wu, S.7    Vuthoori, S.8    Ko, K.9    Zavala, F.10
  • 26
    • 0034545618 scopus 로고    scopus 로고
    • Cutting edge: spontaneous rejection of poorly immunogenic P1 HTR tumors by Stat6-deficient mice
    • Kacha, A.K., F. Fallarino, M.A. Markiewicz, and T.F. Gajewski. 2000. Cutting edge: spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice. J. Immunol. 165:6024-6028.
    • (2000) J. Immunol. , vol.165 , pp. 6024-6028
    • Kacha, A.K.1    Fallarino, F.2    Markiewicz, M.A.3    Gajewski, T.F.4
  • 27
    • 49649121241 scopus 로고    scopus 로고
    • Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma
    • Kline, J., I.E. Brown, Y.Y. Zha, C. Blank, J. Strickler, H. Wouters, L. Zhang, and T.F. Gajewski. 2008. Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma. Clin. Cancer Res. 14:3156-3167. http://dx.doi.org/10.1158/1078-0432.CCR-07-4696
    • (2008) Clin. Cancer Res. , vol.14 , pp. 3156-3167
    • Kline, J.1    Brown, I.E.2    Zha, Y.Y.3    Blank, C.4    Strickler, J.5    Wouters, H.6    Zhang, L.7    Gajewski, T.F.8
  • 28
    • 41149118513 scopus 로고    scopus 로고
    • How dying cells alert the immune system to danger
    • Kono, H., and K.L. Rock. 2008. How dying cells alert the immune system to danger. Nat. Rev. Immunol. 8:279-289. http://dx.doi.org/10.1038/nri2215
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 279-289
    • Kono, H.1    Rock, K.L.2
  • 29
    • 0021713437 scopus 로고
    • Attachment of an antireceptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes
    • Kranz, D.M., S. Tonegawa, and H.N. Eisen. 1984. Attachment of an antireceptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. USA. 81:7922- 7926. http://dx.doi.org/10.1073/pnas.81.24.7922
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 7922-7926
    • Kranz, D.M.1    Tonegawa, S.2    Eisen, H.N.3
  • 30
    • 3142683548 scopus 로고    scopus 로고
    • TLR9- dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function
    • Krug, A., A.R. French, W. Barchet, J.A. Fischer, A. Dzionek, J.T. Pingel, M.M. Orihuela, S. Akira, W.M. Yokoyama, and M. Colonna. 2004. TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function. Immunity. 21:107-119. http://dx.doi.org/10.1016/j.immuni.2004.06.007
    • (2004) Immunity , vol.21 , pp. 107-119
    • Krug, A.1    French, A.R.2    Barchet, W.3    Fischer, J.A.4    Dzionek, A.5    Pingel, J.T.6    Orihuela, M.M.7    Akira, S.8    Yokoyama, W.M.9    Colonna, M.10
  • 33
    • 0038181111 scopus 로고    scopus 로고
    • Lack of terminally differentiated tumor-specific CD8+ T cells at tumor site in spite of antitumor immunity to self-antigens in human metastatic melanoma
    • Mortarini, R., A. Piris, A. Maurichi, A. Molla, I. Bersani, A. Bono, C. Bartoli, M. Santinami, C. Lombardo, F. Ravagnani, et al. 2003. Lack of terminally differentiated tumor-specific CD8+ T cells at tumor site in spite of antitumor immunity to self-antigens in human metastatic melanoma. Cancer Res. 63:2535-2545.
    • (2003) Cancer Res , vol.63 , pp. 2535-2545
    • Mortarini, R.1    Piris, A.2    Maurichi, A.3    Molla, A.4    Bersani, I.5    Bono, A.6    Bartoli, C.7    Santinami, M.8    Lombardo, C.9    Ravagnani, F.10
  • 34
    • 0036138580 scopus 로고    scopus 로고
    • Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
    • Motzer, R.J., J. Bacik, B.A. Murphy, P. Russo, and M. Mazumdar. 2002. Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J. Clin. Oncol. 20:289-296. http://dx.doi.org/10.1200/JCO.20.1.289
    • (2002) J. Clin. Oncol. , vol.20 , pp. 289-296
    • Motzer, R.J.1    Bacik, J.2    Murphy, B.A.3    Russo, P.4    Mazumdar, M.5
  • 35
    • 0035346170 scopus 로고    scopus 로고
    • Novel IFN-alpha receptor promoter polymorphisms
    • Muldoon, J., A. Uriel, S. Khoo, W.E. Ollier, and A.H. Hajeer. 2001. Novel IFN-alpha receptor promoter polymorphisms. Genes Immun. 2:159- 160. http://dx.doi.org/10.1038/sj.gene.6363757
    • (2001) Genes Immun , vol.2 , pp. 159-160
    • Muldoon, J.1    Uriel, A.2    Khoo, S.3    Ollier, W.E.4    Hajeer, A.H.5
  • 37
    • 0037811736 scopus 로고    scopus 로고
    • Immunization with Melan-A peptide-pulsed peripheral blood mononuclear cells plus recombinant human interleukin-12 induces clinical activity and T-cell responses in advanced melanoma
    • Peterson, A.C., H. Harlin, and T.F. Gajewski. 2003. Immunization with Melan-A peptide-pulsed peripheral blood mononuclear cells plus recombinant human interleukin-12 induces clinical activity and T-cell responses in advanced melanoma. J. Clin. Oncol. 21:2342-2348. http://dx.doi.org/10.1200/JCO.2003.12.144
    • (2003) J. Clin. Oncol. , vol.21 , pp. 2342-2348
    • Peterson, A.C.1    Harlin, H.2    Gajewski, T.F.3
  • 39
    • 29644438266 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cells are potent antigenpresenting cells able to activate T cells and mediate tumor rejection
    • Preynat-Seauve, O., P. Schuler, E. Contassot, F. Beermann, B. Huard, and L.E. French. 2006. Tumor-infiltrating dendritic cells are potent antigenpresenting cells able to activate T cells and mediate tumor rejection. J. Immunol. 176:61-67.
    • (2006) J. Immunol. , vol.176 , pp. 61-67
    • Preynat-Seauve, O.1    Schuler, P.2    Contassot, E.3    Beermann, F.4    Huard, B.5    French, L.E.6
  • 40
    • 33947259319 scopus 로고    scopus 로고
    • Immunosuppressive strategies that are mediated by tumor cells
    • Rabinovich, G.A., D. Gabrilovich, and E.M. Sotomayor. 2007. Immunosuppressive strategies that are mediated by tumor cells. Annu. Rev. Immunol. 25:267-296. http://dx.doi.org/10.1146/annurev.immunol.25.022106.141609
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 267-296
    • Rabinovich, G.A.1    Gabrilovich, D.2    Sotomayor, E.M.3
  • 41
    • 42649091089 scopus 로고    scopus 로고
    • Migration of dendritic cell subsets and their precursors
    • Randolph, G.J., J. Ochando, and S. Partida-Sánchez. 2008. Migration of dendritic cell subsets and their precursors. Annu. Rev. Immunol. 26:293-316. http://dx.doi.org/10.1146/annurev.immunol.26.021607.090254
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 293-316
    • Randolph, G.J.1    Ochando, J.2    Partida-Sánchez, S.3
  • 42
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • Scaffidi, P., T. Misteli, and M.E. Bianchi. 2002. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature. 418:191- 195. http://dx.doi.org/10.1038/nature00858
    • (2002) Nature , vol.418 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 43
    • 0023785318 scopus 로고
    • Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice
    • Sha, W.C., C.A. Nelson, R.D. Newberry, D.M. Kranz, J.H. Russell, and D.Y. Loh. 1988. Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice. Nature. 335:271-274. http://dx.doi.org/10.1038/335271a0
    • (1988) Nature , vol.335 , pp. 271-274
    • Sha, W.C.1    Nelson, C.A.2    Newberry, R.D.3    Kranz, D.M.4    Russell, J.H.5    Loh, D.Y.6
  • 44
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • Shi, Y., J.E. Evans, and K.L. Rock. 2003. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature. 425:516- 521. http://dx.doi.org/10.1038/nature01991
    • (2003) Nature , vol.425 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3
  • 45
    • 0036206464 scopus 로고    scopus 로고
    • In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells
    • Speiser, D.E., D. Liénard, M.J. Pittet, P. Batard, D. Rimoldi, P. Guillaume, J.C. Cerottini, and P. Romero. 2002. In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells. Eur. J. Immunol. 32:731-741.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 731-741
    • Speiser, D.E.1    Liénard, D.2    Pittet, M.J.3    Batard, P.4    Rimoldi, D.5    Guillaume, P.6    Cerottini, J.C.7    Romero, P.8
  • 47
    • 30444450839 scopus 로고    scopus 로고
    • Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
    • Stetson, D.B., and R. Medzhitov. 2006a. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity. 24: 93-103. http://dx.doi.org/10.1016/j.immuni.2005.12.003
    • (2006) Immunity , vol.24 , pp. 93-103
    • Stetson, D.B.1    Medzhitov, R.2
  • 48
    • 33748455338 scopus 로고    scopus 로고
    • Type I interferons in host defense
    • Stetson, D.B., and R. Medzhitov. 2006b. Type I interferons in host defense. Immunity. 25:373-381. http://dx.doi.org/10.1016/j.immuni.2006.08.007
    • (2006) Immunity , vol.25 , pp. 373-381
    • Stetson, D.B.1    Medzhitov, R.2
  • 49
    • 34547143110 scopus 로고    scopus 로고
    • DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
    • Takaoka, A., Z. Wang, M.K. Choi, H. Yanai, H. Negishi, T. Ban, Y. Lu, M. Miyagishi, T. Kodama, K. Honda, et al. 2007. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature. 448:501-505. http://dx.doi.org/10.1038/nature06013
    • (2007) Nature , vol.448 , pp. 501-505
    • Takaoka, A.1    Wang, Z.2    Choi, M.K.3    Yanai, H.4    Negishi, H.5    Ban, T.6    Lu, Y.7    Miyagishi, M.8    Kodama, T.9    Honda, K.10
  • 50
    • 41149178259 scopus 로고    scopus 로고
    • Autoantibodies to tumor-associated antigens: reporters from the immune system
    • Tan, E.M., and J. Zhang. 2008. Autoantibodies to tumor-associated antigens: reporters from the immune system. Immunol. Rev. 222:328-340. http://dx.doi.org/10.1111/j.1600-065X.2008.00611.x
    • (2008) Immunol. Rev. , vol.222 , pp. 328-340
    • Tan, E.M.1    Zhang, J.2
  • 51
    • 0029902364 scopus 로고    scopus 로고
    • Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte clone
    • Udaka, K., K.H. Wiesmüller, S. Kienle, G. Jung, and P. Walden. 1996. Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte clone. J. Immunol. 157:670-678.
    • (1996) J. Immunol. , vol.157 , pp. 670-678
    • Udaka, K.1    Wiesmüller, K.H.2    Kienle, S.3    Jung, G.4    Walden, P.5
  • 53
    • 79953059789 scopus 로고    scopus 로고
    • Natural innate and adaptive immunity to cancer
    • Vesely, M.D., M.H. Kershaw, R.D. Schreiber, and M.J. Smyth. 2011. Natural innate and adaptive immunity to cancer. Annu. Rev. Immunol. 29:235- 271. http://dx.doi.org/10.1146/annurev-immunol-031210-101324
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 235-271
    • Vesely, M.D.1    Kershaw, M.H.2    Schreiber, R.D.3    Smyth, M.J.4
  • 56
    • 40449105940 scopus 로고    scopus 로고
    • Equilibrium between host and cancer caused by effector T cells killing tumor stroma
    • Zhang, B., Y. Zhang, N.A. Bowerman, A. Schietinger, Y.X. Fu, D.M. Kranz, D.A. Rowley, and H. Schreiber. 2008. Equilibrium between host and cancer caused by effector T cells killing tumor stroma. Cancer Res. 68:1563-1571. http://dx.doi.org/10.1158/0008-5472.CAN-07-5324
    • (2008) Cancer Res , vol.68 , pp. 1563-1571
    • Zhang, B.1    Zhang, Y.2    Bowerman, N.A.3    Schietinger, A.4    Fu, Y.X.5    Kranz, D.M.6    Rowley, D.A.7    Schreiber, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.