메뉴 건너뛰기




Volumn 33, Issue 4, 2013, Pages 171-180

Interferon-γ-induced necrosis: An antitumor biotherapeutic perspective

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; GAMMA INTERFERON; HYPOXIA INDUCIBLE FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; MANGANESE SUPEROXIDE DISMUTASE; SUNITINIB; TEMSIROLIMUS; VON HIPPEL LINDAU PROTEIN;

EID: 84876114298     PISSN: 10799907     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.2012.0087     Document Type: Review
Times cited : (27)

References (99)
  • 1
    • 0025092625 scopus 로고
    • A phase II trial of recombinant human interferon-gamma and recombinant tumor necrosis factor in patients with advanced gastrointestinal malignancies: Results of a trial terminated by excessive toxicity
    • Abbruzzese JL, Levin B, Ajani JA, Faintuch JS, Pazdur R, Saks S, Edwards C, Gutterman JU. 1990. A phase II trial of recombinant human interferon-gamma and recombinant tumor necrosis factor in patients with advanced gastrointestinal malignancies: results of a trial terminated by excessive toxicity. J Biol Response Mod 9(5):522-527.
    • (1990) J Biol Response Mod , vol.9 , Issue.5 , pp. 522-527
    • Abbruzzese, J.L.1    Levin, B.2    Ajani, J.A.3    Faintuch, J.S.4    Pazdur, R.5    Saks, S.6    Edwards, C.7    Gutterman, J.U.8
  • 2
    • 14944366562 scopus 로고    scopus 로고
    • VHL expression in renal cell carcinoma sensitizes to bortezomib (PS-341) through an NFkappaB- dependent mechanism
    • An J, Fisher M, Rettig MB. 2005. VHL expression in renal cell carcinoma sensitizes to bortezomib (PS-341) through an NFkappaB- dependent mechanism. Oncogene 24(9):1563-1570.
    • (2005) Oncogene , vol.24 , Issue.9 , pp. 1563-1570
    • An, J.1    Fisher, M.2    Rettig, M.B.3
  • 3
    • 23844527189 scopus 로고    scopus 로고
    • Mechanism of von Hippel-Lindau protein- mediated suppression of nuclear factor kappa B activity
    • An J, Rettig MB. 2005. Mechanism of von Hippel-Lindau protein- mediated suppression of nuclear factor kappa B activity. Mol Cell Biol 25(17):7546-7556.
    • (2005) Mol Cell Biol , vol.25 , Issue.17 , pp. 7546-7556
    • An, J.1    Rettig, M.B.2
  • 4
    • 33846805694 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition sensitizes renal cell carcinoma cells to the cytotoxic effects of bortezomib
    • An J, Rettig MB. 2007. Epidermal growth factor receptor inhibition sensitizes renal cell carcinoma cells to the cytotoxic effects of bortezomib. Mol Cancer Ther 6(1):61-69.
    • (2007) Mol Cancer Ther , vol.6 , Issue.1 , pp. 61-69
    • An, J.1    Rettig, M.B.2
  • 5
    • 4444301713 scopus 로고    scopus 로고
    • Maximal apoptosis of renal cell carcinoma by the proteasome inhibitor bortezomib is nuclear factor-kappaB dependent
    • An J, Sun Y, FisherM, RettigMB. 2004.Maximal apoptosis of renal cell carcinoma by the proteasome inhibitor bortezomib is nuclear factor-kappaB dependent. Mol Cancer Ther 3(6):727-736.
    • (2004) Mol Cancer Ther , vol.3 , Issue.6 , pp. 727-736
    • An, J.1    Sun, Y.2    Fisher, M.3    Rettig, M.B.4
  • 6
    • 0034788744 scopus 로고    scopus 로고
    • Design of the linkers which effectively separate domains of a bifunctional fusion protein
    • Arai R, Ueda H, Kitayama A, Kamiya N, Nagamune T. 2001. Design of the linkers which effectively separate domains of a bifunctional fusion protein. Protein Eng 14(8):529-532.
    • (2001) Protein Eng , vol.14 , Issue.8 , pp. 529-532
    • Arai, R.1    Ueda, H.2    Kitayama, A.3    Kamiya, N.4    Nagamune, T.5
  • 7
    • 0024809918 scopus 로고
    • Successful treatment of metastatic renal cell carcinoma with a biologically active dose of recombinant interferon-gamma
    • Aulitzky W, Gastl G, Aulitzky WE, Herold M, Kemmler J, Mull B, Frick J, Huber C. 1989. Successful treatment of metastatic renal cell carcinoma with a biologically active dose of recombinant interferon-gamma. J Clin Oncol 7(12):1875-1884.
    • (1989) J Clin Oncol , vol.7 , Issue.12 , pp. 1875-1884
    • Aulitzky, W.1    Gastl, G.2    Aulitzky, W.E.3    Herold, M.4    Kemmler, J.5    Mull, B.6    Frick, J.7    Huber, C.8
  • 8
    • 0033970831 scopus 로고    scopus 로고
    • Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway
    • Balachandran S, Roberts PC, Kipperman T, Bhalla KN, Compans RW, Archer DR, Barber GN. 2000. Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway. J Virol 74(3):1513-1523.
    • (2000) J Virol , vol.74 , Issue.3 , pp. 1513-1523
    • Balachandran, S.1    Roberts, P.C.2    Kipperman, T.3    Bhalla, K.N.4    Compans, R.W.5    Archer, D.R.6    Barber, G.N.7
  • 9
    • 9244236078 scopus 로고    scopus 로고
    • A FADD-dependent innate immune mechanism in mammalian cells
    • Balachandran S, Thomas E, Barber GN. 2004. A FADD-dependent innate immune mechanism in mammalian cells. Nature 432(7015):401-405.
    • (2004) Nature , vol.432 , Issue.7015 , pp. 401-405
    • Balachandran, S.1    Thomas, E.2    Barber, G.N.3
  • 10
    • 79952384759 scopus 로고    scopus 로고
    • Distinct roles for the NF-kappa B RelA subunit during antiviral innate immune responses
    • Basagoudanavar SH, Thapa RJ, Nogusa S, Wang J, Beg AA, Balachandran S. 2011. Distinct roles for the NF-kappa B RelA subunit during antiviral innate immune responses. J Virol 85(6):2599-2610.
    • (2011) J Virol , vol.85 , Issue.6 , pp. 2599-2610
    • Basagoudanavar, S.H.1    Thapa, R.J.2    Nogusa, S.3    Wang, J.4    Beg, A.A.5    Balachandran, S.6
  • 11
    • 58149202128 scopus 로고    scopus 로고
    • Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
    • Baud V, Karin M. 2009. Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls. Nat Rev Drug Discov 8(1):33-40.
    • (2009) Nat Rev Drug Discov , vol.8 , Issue.1 , pp. 33-40
    • Baud, V.1    Karin, M.2
  • 12
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
    • Beg AA, Baltimore D. 1996. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274(5288):782-784.
    • (1996) Science , vol.274 , Issue.5288 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 13
    • 80052014052 scopus 로고    scopus 로고
    • Inflammation meets cancer, with NF-kappaB as the matchmaker
    • Ben-Neriah Y, Karin M. 2011. Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat Immunol 12(8):715-723.
    • (2011) Nat Immunol , vol.12 , Issue.8 , pp. 715-723
    • Ben-Neriah, Y.1    Karin, M.2
  • 14
    • 0022540085 scopus 로고
    • Hyponatremia and other toxic effects during a phase i trial of recombinant human gamma interferon and vinblastine
    • Bennett CL, Vogelzang NJ, Ratain MJ, Reich SD. 1986. Hyponatremia and other toxic effects during a phase I trial of recombinant human gamma interferon and vinblastine. Cancer Treat Rep 70(9):1081-1084.
    • (1986) Cancer Treat Rep , vol.70 , Issue.9 , pp. 1081-1084
    • Bennett, C.L.1    Vogelzang, N.J.2    Ratain, M.J.3    Reich, S.D.4
  • 16
    • 33749261659 scopus 로고    scopus 로고
    • Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
    • Bours MJ, Swennen EL, Di Virgilio F, Cronstein BN, Dagnelie PC. 2006. Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther 112(2):358-404.
    • (2006) Pharmacol Ther , vol.112 , Issue.2 , pp. 358-404
    • Bours, M.J.1    Swennen, E.L.2    Di Virgilio, F.3    Cronstein, B.N.4    Dagnelie, P.C.5
  • 18
    • 77952944929 scopus 로고    scopus 로고
    • Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex
    • Brooks AD, Jacobsen KM, Li W, Shanker A, Sayers TJ. 2010. Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex. Mol Cancer Res 8(5):729- 738.
    • (2010) Mol Cancer Res , vol.8 , Issue.5 , pp. 729-738
    • Brooks, A.D.1    Jacobsen, K.M.2    Li, W.3    Shanker, A.4    Sayers, T.J.5
  • 20
    • 79951702955 scopus 로고    scopus 로고
    • Bortezomib as the first proteasome inhibitor anticancer drug: Current status and future perspectives
    • Chen D, Frezza M, Schmitt S, Kanwar J, Dou QP. 2011. Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives. Curr Cancer Drug Targets 11(3):239-253.
    • (2011) Curr Cancer Drug Targets , vol.11 , Issue.3 , pp. 239-253
    • Chen, D.1    Frezza, M.2    Schmitt, S.3    Kanwar, J.4    Dou, Q.P.5
  • 21
    • 78649347932 scopus 로고    scopus 로고
    • Evaluation and management of the renal mass
    • Chen DY, Uzzo RG. 2011. Evaluation and management of the renal mass. Med Clin North Am 95(1):179-189.
    • (2011) Med Clin North Am , vol.95 , Issue.1 , pp. 179-189
    • Chen, D.Y.1    Uzzo, R.G.2
  • 22
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: A beautiful pathway
    • Chen G, Goeddel DV. 2002. TNF-R1 signaling: a beautiful pathway. Science 296(5573):1634-1635.
    • (2002) Science , vol.296 , Issue.5573 , pp. 1634-1635
    • Chen, G.1    Goeddel, D.V.2
  • 24
    • 84856283240 scopus 로고    scopus 로고
    • The ubiquitin-proteasome system (UPS) and the mechanism of action of bortezomib
    • Cvek B, Dvorak Z. 2011. The ubiquitin-proteasome system (UPS) and the mechanism of action of bortezomib. Curr Pharm Des 17(15):1483-1499.
    • (2011) Curr Pharm des , vol.17 , Issue.15 , pp. 1483-1499
    • Cvek, B.1    Dvorak, Z.2
  • 25
    • 0023885028 scopus 로고
    • A phase i trial of intraperitoneal recombinant gamma-interferon in advanced ovarian carcinoma
    • D'Acquisto R, Markman M, Hakes T, Rubin S, Hoskins W, Lewis JL, Jr. 1988. A phase I trial of intraperitoneal recombinant gamma-interferon in advanced ovarian carcinoma. J Clin Oncol 6(4):689-695.
    • (1988) J Clin Oncol , vol.6 , Issue.4 , pp. 689-695
    • D'Acquisto, R.1    Markman, M.2    Hakes, T.3    Rubin, S.4    Hoskins, W.5    Lewis Jr., J.L.6
  • 26
    • 0035873486 scopus 로고    scopus 로고
    • RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway
    • Deb A, Haque SJ, Mogensen T, Silverman RH, Williams BR. 2001. RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway. J Immunol 166(10):6170-6180.
    • (2001) J Immunol , vol.166 , Issue.10 , pp. 6170-6180
    • Deb, A.1    Haque, S.J.2    Mogensen, T.3    Silverman, R.H.4    Williams, B.R.5
  • 27
    • 0028831202 scopus 로고
    • Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferoninduced cell death
    • Deiss LP, Feinstein E, Berissi H, Cohen O, Kimchi A. 1995. Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferoninduced cell death. Genes Dev 9(1):15-30.
    • (1995) Genes Dev , vol.9 , Issue.1 , pp. 15-30
    • Deiss, L.P.1    Feinstein, E.2    Berissi, H.3    Cohen, O.4    Kimchi, A.5
  • 28
    • 23644449236 scopus 로고    scopus 로고
    • Identification of CD70 as a diagnostic biomarker for clear cell renal cell carcinoma by gene expression profiling, real-time RT-PCR and immunohistochemistry
    • Diegmann J, Junker K, Gerstmayer B, Bosio A, Hindermann W, Rosenhahn J, von Eggeling F. 2005. Identification of CD70 as a diagnostic biomarker for clear cell renal cell carcinoma by gene expression profiling, real-time RT-PCR and immunohistochemistry. Eur J Cancer 41(12):1794-1801.
    • (2005) Eur J Cancer , vol.41 , Issue.12 , pp. 1794-1801
    • Diegmann, J.1    Junker, K.2    Gerstmayer, B.3    Bosio, A.4    Hindermann, W.5    Rosenhahn, J.6    Von Eggeling, F.7
  • 33
    • 0036201914 scopus 로고    scopus 로고
    • Transcytosis and catabolism of antibody
    • Ghetie V, Ward ES. 2002. Transcytosis and catabolism of antibody. Immunol Res 25(2):97-113.
    • (2002) Immunol Res , vol.25 , Issue.2 , pp. 97-113
    • Ghetie, V.1    Ward, E.S.2
  • 34
    • 33750466230 scopus 로고    scopus 로고
    • Introduction to NF-kappaB: Players, pathways, perspectives
    • Gilmore TD. 2006. Introduction to NF-kappaB: players, pathways, perspectives. Oncogene 25(51):6680-6684.
    • (2006) Oncogene , vol.25 , Issue.51 , pp. 6680-6684
    • Gilmore, T.D.1
  • 37
    • 84861845402 scopus 로고    scopus 로고
    • The updated biology of hypoxia-inducible factor
    • Greer SN, Metcalf JL, Wang Y, Ohh M. 2012. The updated biology of hypoxia-inducible factor. EMBO J 31(11):2448-2460.
    • (2012) EMBO J , vol.31 , Issue.11 , pp. 2448-2460
    • Greer, S.N.1    Metcalf, J.L.2    Wang, Y.3    Ohh, M.4
  • 38
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • Hayden MS, Ghosh S. 2004. Signaling to NF-kappaB. Genes Dev 18(18):2195-2224.
    • (2004) Genes Dev , vol.18 , Issue.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 39
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden MS, Ghosh S. 2008. Shared principles in NF-kappaB signaling. Cell 132(3):344-362.
    • (2008) Cell , vol.132 , Issue.3 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 40
    • 57649181391 scopus 로고    scopus 로고
    • Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
    • Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ, Yuan J. 2008. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 135(7):1311-1323.
    • (2008) Cell , vol.135 , Issue.7 , pp. 1311-1323
    • Hitomi, J.1    Christofferson, D.E.2    Ng, A.3    Yao, J.4    Degterev, A.5    Xavier, R.J.6    Yuan, J.7
  • 41
    • 65949091346 scopus 로고    scopus 로고
    • Targeting mTOR in renal cell carcinoma
    • Hudes GR. 2009. Targeting mTOR in renal cell carcinoma. Cancer 115(10 Suppl):2313-2320.
    • (2009) Cancer , vol.115 , Issue.10 SUPPL. , pp. 2313-2320
    • Hudes, G.R.1
  • 44
    • 0030692715 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB
    • Jones PL, Ping D, Boss JM. 1997. Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB. Mol Cell Biol 17(12): 6970-6981.
    • (1997) Mol Cell Biol , vol.17 , Issue.12 , pp. 6970-6981
    • Jones, P.L.1    Ping, D.2    Boss, J.M.3
  • 46
    • 54549113030 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer
    • Kaelin WG, Jr. 2008. The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer. Nat Rev Cancer 8(11):865-873.
    • (2008) Nat Rev Cancer , vol.8 , Issue.11 , pp. 865-873
    • Kaelin Jr., W.G.1
  • 47
    • 2342597973 scopus 로고    scopus 로고
    • Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth
    • Kondo K, Kim WY, Lechpammer M, Kaelin WG, Jr. 2003. Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth. PLoS Biol 1(3):E83.
    • (2003) PLoS Biol , vol.1 , Issue.3
    • Kondo, K.1    Kim, W.Y.2    Lechpammer, M.3    Kaelin Jr., W.G.4
  • 50
    • 0021969122 scopus 로고
    • Pharmacokinetics, singledose tolerance, and biological activity of recombinant gammainterferon in cancer patients
    • Kurzrock R, Rosenblum MG, Sherwin SA, Rios A, Talpaz M, Quesada JR, Gutterman JU. 1985. Pharmacokinetics, singledose tolerance, and biological activity of recombinant gammainterferon in cancer patients. Cancer Res 45(6):2866-2872.
    • (1985) Cancer Res , vol.45 , Issue.6 , pp. 2866-2872
    • Kurzrock, R.1    Rosenblum, M.G.2    Sherwin, S.A.3    Rios, A.4    Talpaz, M.5    Quesada, J.R.6    Gutterman, J.U.7
  • 53
    • 77952263737 scopus 로고    scopus 로고
    • The genetic basis of kidney cancer: A metabolic disease
    • Linehan WM, Srinivasan R, Schmidt LS. 2010. The genetic basis of kidney cancer: a metabolic disease. Nat Rev Urol 7(5):277- 285.
    • (2010) Nat Rev Urol , vol.7 , Issue.5 , pp. 277-285
    • Linehan, W.M.1    Srinivasan, R.2    Schmidt, L.S.3
  • 57
    • 77953812468 scopus 로고    scopus 로고
    • The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies
    • Mathupala SP, Ko YH, Pedersen PL. 2010. The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies. Biochim Biophys Acta 1797(6-7):1225-1230.
    • (2010) Biochim Biophys Acta , vol.1797 , Issue.6-7 , pp. 1225-1230
    • Mathupala, S.P.1    Ko, Y.H.2    Pedersen, P.L.3
  • 59
    • 0041335450 scopus 로고    scopus 로고
    • Chimeric TNT-3 antibody/murine interferon-gamma fusion protein for the immunotherapy of solid malignancies
    • Mizokami MM, Hu P, Khawli LA, Li J, Epstein AL. 2003. Chimeric TNT-3 antibody/murine interferon-gamma fusion protein for the immunotherapy of solid malignancies. Hybrid Hybridomics 22(4):197-207.
    • (2003) Hybrid Hybridomics , vol.22 , Issue.4 , pp. 197-207
    • Mizokami, M.M.1    Hu, P.2    Khawli, L.A.3    Li, J.4    Epstein, A.L.5
  • 61
    • 0036138580 scopus 로고    scopus 로고
    • Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
    • Motzer RJ, Bacik J, Murphy BA, Russo P, Mazumdar M. 2002. Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol 20(1):289-296.
    • (2002) J Clin Oncol , vol.20 , Issue.1 , pp. 289-296
    • Motzer, R.J.1    Bacik, J.2    Murphy, B.A.3    Russo, P.4    Mazumdar, M.5
  • 62
    • 0033514050 scopus 로고    scopus 로고
    • Interferon-alpha and survival in metastatic renal carcinoma: Early results of a randomised controlled trial
    • MRCCC Medical Research Council Renal Cancer Collaborators
    • MRCCC. 1999. Interferon-alpha and survival in metastatic renal carcinoma: early results of a randomised controlled trial. Medical Research Council Renal Cancer Collaborators. Lancet 353(9146):14-17.
    • (1999) Lancet , vol.353 , Issue.9146 , pp. 14-17
  • 64
    • 45249124315 scopus 로고    scopus 로고
    • Role of the VHL (von Hippel-Lindau) gene in renal cancer: A multifunctional tumour suppressor
    • Nyhan MJ, O'Sullivan GC, McKenna SL. 2008. Role of the VHL (von Hippel-Lindau) gene in renal cancer: a multifunctional tumour suppressor. Biochem Soc Trans 36(Pt 3):472-478.
    • (2008) Biochem Soc Trans , vol.36 , Issue.PART 3 , pp. 472-478
    • Nyhan, M.J.1    O'Sullivan, G.C.2    McKenna, S.L.3
  • 65
    • 0023760276 scopus 로고
    • Recombinant interferon gamma in the treatment of metastatic renal cell carcinoma. Results of a phase II trial
    • Otto U, Conrad S, Schneider AW, Klosterhalfen H. 1988. Recombinant interferon gamma in the treatment of metastatic renal cell carcinoma. Results of a phase II trial. Arzneimittelforschung 38(11):1658-1660.
    • (1988) Arzneimittelforschung , vol.38 , Issue.11 , pp. 1658-1660
    • Otto, U.1    Conrad, S.2    Schneider, A.W.3    Klosterhalfen, H.4
  • 66
    • 77957997621 scopus 로고    scopus 로고
    • Targeted therapies for renal cell carcinoma: Understanding their impact on survival
    • Pal SK, Figlin RA. 2010. Targeted therapies for renal cell carcinoma: understanding their impact on survival. Target Oncol 5(2):131-138.
    • (2010) Target Oncol , vol.5 , Issue.2 , pp. 131-138
    • Pal, S.K.1    Figlin, R.A.2
  • 67
    • 84861610591 scopus 로고    scopus 로고
    • Immunocytokines: A novel class of potent armed antibodies
    • Pasche N, Neri D. 2012. Immunocytokines: a novel class of potent armed antibodies. Drug Discov Today 17(11-12): 583-590.
    • (2012) Drug Discov Today , vol.17 , Issue.11-12 , pp. 583-590
    • Pasche, N.1    Neri, D.2
  • 68
    • 79960115481 scopus 로고    scopus 로고
    • The role of nuclear factor kappaB in the interferon response
    • Pfeffer LM. 2011. The role of nuclear factor kappaB in the interferon response. J Interferon Cytokine Res 31(7):553-559.
    • (2011) J Interferon Cytokine Res , vol.31 , Issue.7 , pp. 553-559
    • Pfeffer, L.M.1
  • 70
    • 79955689582 scopus 로고    scopus 로고
    • Targeted-therapy in advanced renal cell carcinoma
    • Pirrotta MT, Bernardeschi P, Fiorentini G. 2011. Targeted-therapy in advanced renal cell carcinoma. Curr Med Chem 18(11): 1651-1657.
    • (2011) Curr Med Chem , vol.18 , Issue.11 , pp. 1651-1657
    • Pirrotta, M.T.1    Bernardeschi, P.2    Fiorentini, G.3
  • 71
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I- and type-II-interferon- mediated signalling
    • Platanias LC. 2005. Mechanisms of type-I- and type-II-interferon- mediated signalling. Nat Rev Immunol 5(5):375-386.
    • (2005) Nat Rev Immunol , vol.5 , Issue.5 , pp. 375-386
    • Platanias, L.C.1
  • 72
    • 0023156669 scopus 로고
    • Phase II studies of recombinant human interferon gamma in metastatic renal cell carcinoma
    • Quesada JR, Kurzrock R, Sherwin SA, Gutterman JU. 1987. Phase II studies of recombinant human interferon gamma in metastatic renal cell carcinoma. J Biol Response Mod 6(1): 20-27.
    • (1987) J Biol Response Mod , vol.6 , Issue.1 , pp. 20-27
    • Quesada, J.R.1    Kurzrock, R.2    Sherwin, S.A.3    Gutterman, J.U.4
  • 73
    • 84856227857 scopus 로고    scopus 로고
    • Mitochondrial metabolism inhibitors for cancer therapy
    • Ramsay EE, Hogg PJ, Dilda PJ. 2011. Mitochondrial metabolism inhibitors for cancer therapy. Pharm Res 28(11):2731-2744.
    • (2011) Pharm Res , vol.28 , Issue.11 , pp. 2731-2744
    • Ramsay, E.E.1    Hogg, P.J.2    Dilda, P.J.3
  • 74
    • 0022972731 scopus 로고
    • Phase I/II trial of human recombinant interferon gamma in renal cell carcinoma
    • Rinehart JJ, Malspeis L, Young D, Neidhart JA. 1986. Phase I/II trial of human recombinant interferon gamma in renal cell carcinoma. J Biol Response Mod 5(4):300-308.
    • (1986) J Biol Response Mod , vol.5 , Issue.4 , pp. 300-308
    • Rinehart, J.J.1    Malspeis, L.2    Young, D.3    Neidhart, J.A.4
  • 79
    • 0038706226 scopus 로고    scopus 로고
    • Generation of human interferon gamma and tumor Necrosis factor alpha chimeric TNT-3 fusion proteins
    • Sharifi J, Khawli LA, Hu P, Li J, Epstein AL. 2002. Generation of human interferon gamma and tumor Necrosis factor alpha chimeric TNT-3 fusion proteins. Hybrid Hybridomics 21(6): 421-432.
    • (2002) Hybrid Hybridomics , vol.21 , Issue.6 , pp. 421-432
    • Sharifi, J.1    Khawli, L.A.2    Hu, P.3    Li, J.4    Epstein, A.L.5
  • 81
    • 0030853434 scopus 로고    scopus 로고
    • Classification of renal cell carcinoma: Workgroup No. 1
    • Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC)
    • Storkel S, Eble JN, Adlakha K, Amin M, Blute ML, Bostwick DG, Darson M, Delahunt B, Iczkowski K. 1997. Classification of renal cell carcinoma: Workgroup No. 1. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC). Cancer 80(5):987-989.
    • (1997) Cancer , vol.80 , Issue.5 , pp. 987-989
    • Storkel, S.1    Eble, J.N.2    Adlakha, K.3    Amin, M.4    Blute, M.L.5    Bostwick, D.G.6    Darson, M.7    Delahunt, B.8    Iczkowski, K.9
  • 82
    • 2942689618 scopus 로고    scopus 로고
    • The role of von Hippel- Lindau tumor suppressor protein and hypoxia in renal clear cell carcinoma
    • Sufan RI, Jewett MA, Ohh M. 2004. The role of von Hippel- Lindau tumor suppressor protein and hypoxia in renal clear cell carcinoma. Am J Physiol Renal Physiol 287(1):F1-F6.
    • (2004) Am J Physiol Renal Physiol , vol.287 , Issue.1
    • Sufan, R.I.1    Jewett, M.A.2    Ohh, M.3
  • 83
    • 84862907788 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
    • Sun L, Wang H, Wang Z, He S, Chen S, Liao D, Wang L, Yan J, Liu W, Lei X, Wang X. 2012. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 148(1-2):213-227.
    • (2012) Cell , vol.148 , Issue.1-2 , pp. 213-227
    • Sun, L.1    Wang, H.2    Wang, Z.3    He, S.4    Chen, S.5    Liao, D.6    Wang, L.7    Yan, J.8    Liu, W.9    Lei, X.10    Wang, X.11
  • 84
    • 0036467492 scopus 로고    scopus 로고
    • The interferon-alpha/beta system in antiviral responses: A multimodal machinery of gene regulation by the IRF family of transcription factors
    • Taniguchi T, Takaoka A. 2002. The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors. Curr Opin Immunol 14(1):111-116.
    • (2002) Curr Opin Immunol , vol.14 , Issue.1 , pp. 111-116
    • Taniguchi, T.1    Takaoka, A.2
  • 86
    • 0023067301 scopus 로고
    • Ferritin: Structure, gene regulation, and cellular function in animals, plants, and microorganisms
    • Theil EC. 1987. Ferritin: structure, gene regulation, and cellular function in animals, plants, and microorganisms. Annu Rev Biochem 56:289-315.
    • (1987) Annu Rev Biochem , vol.56 , pp. 289-315
    • Theil, E.C.1
  • 87
    • 62349114041 scopus 로고    scopus 로고
    • Extracellular ATP in the immune system: More than just a danger signal
    • Trautmann A. 2009. Extracellular ATP in the immune system: more than just a danger signal. Sci Signal 2(56):pe6.
    • (2009) Sci Signal , vol.2 , Issue.56
    • Trautmann, A.1
  • 90
    • 84862909353 scopus 로고    scopus 로고
    • The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
    • Wang Z, Jiang H, Chen S, Du F, Wang X. 2012. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 148(1-2):228-243.
    • (2012) Cell , vol.148 , Issue.1-2 , pp. 228-243
    • Wang, Z.1    Jiang, H.2    Chen, S.3    Du, F.4    Wang, X.5
  • 91
    • 77951614830 scopus 로고    scopus 로고
    • Monoclonal antibodies: Versatile platforms for cancer immunotherapy
    • Weiner LM, Surana R, Wang S. 2010. Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nat Rev Immunol 10(5):317-327.
    • (2010) Nat Rev Immunol , vol.10 , Issue.5 , pp. 317-327
    • Weiner, L.M.1    Surana, R.2    Wang, S.3
  • 92
    • 0027192081 scopus 로고
    • Immunotherapy for metastatic renal cell carcinoma
    • Wirth MP. 1993. Immunotherapy for metastatic renal cell carcinoma. Urol Clin North Am 20(2):283-295.
    • (1993) Urol Clin North Am , vol.20 , Issue.2 , pp. 283-295
    • Wirth, M.P.1
  • 93
    • 0029908874 scopus 로고    scopus 로고
    • Targeting gamma interferon to tumor cells by a genetically engineered fusion protein secreted from myeloma cells
    • Xiang J, Qi Y, Cook D, Moyana T. 1996. Targeting gamma interferon to tumor cells by a genetically engineered fusion protein secreted from myeloma cells. Hum Antibodies Hybridomas 7(1):2-10.
    • (1996) Hum Antibodies Hybridomas , vol.7 , Issue.1 , pp. 2-10
    • Xiang, J.1    Qi, Y.2    Cook, D.3    Moyana, T.4
  • 94
    • 0027333497 scopus 로고
    • Recombinant bifunctional molecule FV/IFN-gamma possesses the anti-tumor FV as well as the gamma interferon activities
    • Xiang J, Qi Y, Luo X, Liu E. 1993. Recombinant bifunctional molecule FV/IFN-gamma possesses the anti-tumor FV as well as the gamma interferon activities. Cancer Biother 8(4):327- 337.
    • (1993) Cancer Biother , vol.8 , Issue.4 , pp. 327-337
    • Xiang, J.1    Qi, Y.2    Luo, X.3    Liu, E.4
  • 96
    • 45149139749 scopus 로고
    • Phase II trial of high dose recombinant gamma-interferon in advanced hepatocellular carcinoma
    • Yoshida T, Okazaki N, Yoshino M, Okhura H, Shimada Y. 1990. Phase II trial of high dose recombinant gamma-interferon in advanced hepatocellular carcinoma. Eur J Cancer 26(4): 545-546.
    • (1990) Eur J Cancer , vol.26 , Issue.4 , pp. 545-546
    • Yoshida, T.1    Okazaki, N.2    Yoshino, M.3    Okhura, H.4    Shimada, Y.5
  • 97
    • 0036143372 scopus 로고    scopus 로고
    • Interferon-gamma therapy: Evaluation of routes of administration and delivery systems
    • Younes HM, Amsden BG. 2002. Interferon-gamma therapy: evaluation of routes of administration and delivery systems. J Pharm Sci 91(1):2-17.
    • (2002) J Pharm Sci , vol.91 , Issue.1 , pp. 2-17
    • Younes, H.M.1    Amsden, B.G.2
  • 98
    • 67650812332 scopus 로고    scopus 로고
    • RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
    • Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, Dong MQ, Han J. 2009. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325(5938):332-336.
    • (2009) Science , vol.325 , Issue.5938 , pp. 332-336
    • Zhang, D.W.1    Shao, J.2    Lin, J.3    Zhang, N.4    Lu, B.J.5    Lin, S.C.6    Dong, M.Q.7    Han, J.8
  • 99
    • 84859467770 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
    • Zhao J, Jitkaew S, Cai Z, Choksi S, Li Q, Luo J, Liu ZG. 2012. Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc Natl Acad Sci U S A 109(14):5322-5327.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.14 , pp. 5322-5327
    • Zhao, J.1    Jitkaew, S.2    Cai, Z.3    Choksi, S.4    Li, Q.5    Luo, J.6    Liu, Z.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.