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Volumn 9, Issue 3, 2013, Pages 317-327

Inhibiting autophagy potentiates the anticancer activity of IFN1/IFNα in chronic myeloid leukemia cells

Author keywords

Apoptosis; Autophagy; Chronic Myeloid Leukemia; IFN1; Immunotherapy

Indexed keywords

ALPHA INTERFERON; BECLIN 1; CARISOPRODOL; CATHEPSIN B; FLICE INHIBITORY PROTEIN; JANUS KINASE 1; STAT1 PROTEIN;

EID: 84877337914     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.22923     Document Type: Article
Times cited : (46)

References (51)
  • 1
    • 0020590588 scopus 로고
    • Leukocyte interferon-induced myeloid cytoreduction in chronic myelogenous leukemia
    • PMID:6192858
    • Talpaz M, McCredie KB, Mavligit GM, Gutterman JU. Leukocyte interferon-induced myeloid cytoreduction in chronic myelogenous leukemia. Blood 1983; 62:689-92; PMID:6192858
    • (1983) Blood , vol.62 , pp. 689-692
    • Talpaz, M.1    McCredie, K.B.2    Mavligit, G.M.3    Gutterman, J.U.4
  • 2
    • 34548140132 scopus 로고    scopus 로고
    • The role of interferonalpha in the treatment of chronic myeloid leukemia
    • PMID:17703986
    • Kujawski LA, Talpaz M. The role of interferonalpha in the treatment of chronic myeloid leukemia. Cytokine Growth Factor Rev 2007; 18:459-71; PMID:17703986; http://dx.doi.org/10.1016/j.cytogfr. 2007.06.015
    • (2007) Cytokine Growth Factor Rev , vol.18 , pp. 459-471
    • Kujawski, L.A.1    Talpaz, M.2
  • 3
    • 0038483374 scopus 로고    scopus 로고
    • Randomized comparison of interferon alpha and hydroxyurea with hydroxyurea monotherapy in chronic myeloid leukemia (CML-study II): Prolongation of survival by the combination of interferon alpha and hydroxyurea
    • German CMLStudy Group. PMID:12886239
    • Hehlmann R, Berger U, Pfirrmann M, Hochhaus A, Metzgeroth G, Maywald O, et al.; German CMLStudy Group. Randomized comparison of interferon alpha and hydroxyurea with hydroxyurea monotherapy in chronic myeloid leukemia (CML-study II): Prolongation of survival by the combination of interferon alpha and hydroxyurea. Leukemia 2003; 17:1529-37; PMID:12886239; http://dx.doi.org/10. 1038/sj.leu.2403006
    • (2003) Leukemia , vol.17 , pp. 1529-1537
    • Hehlmann, R.1    Berger, U.2    Pfirrmann, M.3    Hochhaus, A.4    Metzgeroth, G.5    Maywald, O.6
  • 4
    • 12944284583 scopus 로고    scopus 로고
    • Transcriptional profiling identifies gene expression changes associated with IFN-alpha tolerance in hepatitis C-related hepatocellular carcinoma cells
    • PMID:15709204
    • Wong N, Chan KY, Macgregor PF, Lai PB, Squire JA, Beheshti B, et al. Transcriptional profiling identifies gene expression changes associated with IFN-alpha tolerance in hepatitis C-related hepatocellular carcinoma cells. Clin Cancer Res 2005; 11:1319-26; PMID:15709204
    • (2005) Clin Cancer Res , vol.11 , pp. 1319-1326
    • Wong, N.1    Chan, K.Y.2    Macgregor, P.F.3    Lai, P.B.4    Squire, J.A.5    Beheshti, B.6
  • 5
    • 0037108433 scopus 로고    scopus 로고
    • Constitutive expression of SOCS3 confers resistance to IFN-alpha in chronic myelogenous leukemia cells
    • PMID:12351404
    • Sakai I, Takeuchi K, Yamauchi H, Narumi H, Fujita S. Constitutive expression of SOCS3 confers resistance to IFN-alpha in chronic myelogenous leukemia cells. Blood 2002; 100:2926-31; PMID:12351404; http://dx.doi.org/10. 1182/blood-2002-01-0073
    • (2002) Blood , vol.100 , pp. 2926-2931
    • Sakai, I.1    Takeuchi, K.2    Yamauchi, H.3    Narumi, H.4    Fujita, S.5
  • 6
    • 77956404377 scopus 로고    scopus 로고
    • Eaten alive: A history of macroautophagy
    • PMID:20811353
    • Yang Z, Klionsky DJ. Eaten alive: A history of macroautophagy. Nat Cell Biol 2010; 12:814-22; PMID:20811353; http://dx.doi.org/10.1038/ncb0910-814
    • (2010) Nat Cell Biol , vol.12 , pp. 814-822
    • Yang, Z.1    Klionsky, D.J.2
  • 7
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • PMID:20965422
    • Kroemer G, Mariño G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40:280-93; PMID:20965422; http://dx.doi.org/10.1016/j. molcel. 2010.09.023
    • (2010) Mol Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Mariño, G.2    Levine, B.3
  • 8
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • PMID:18191218
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132:27-42; PMID:18191218; http://dx.doi.org/10.1016/j.cell.2007.12.018
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 9
    • 79951847989 scopus 로고    scopus 로고
    • Principles and current strategies for targeting autophagy for cancer treatment
    • PMID:21325294
    • Amaravadi RK, Lippincott-Schwartz J, Yin XM, Weiss WA, Takebe N, Timmer W, et al. Principles and current strategies for targeting autophagy for cancer treatment. Clin Cancer Res 2011; 17:654-66; PMID:21325294; http://dx.doi.org/10. 1158/1078-0432.CCR-10-2634
    • (2011) Clin Cancer Res , vol.17 , pp. 654-666
    • Amaravadi, R.K.1    Lippincott-Schwartz, J.2    Yin, X.M.3    Weiss, W.A.4    Takebe, N.5    Timmer, W.6
  • 10
    • 79955469013 scopus 로고    scopus 로고
    • Autophagy is essential to suppress cell stress and to allow BCR-Ablmediated leukemogenesis
    • PMID:21151168
    • Altman BJ, Jacobs SR, Mason EF, Michalek RD, MacIntyre AN, Coloff JL, et al. Autophagy is essential to suppress cell stress and to allow BCR-Ablmediated leukemogenesis. Oncogene 2011; 30:1855-67; PMID:21151168; http://dx.doi.org/10. 1038/onc.2010.561
    • (2011) Oncogene , vol.30 , pp. 1855-1867
    • Altman, B.J.1    Jacobs, S.R.2    Mason, E.F.3    Michalek, R.D.4    MacIntyre, A.N.5    Coloff, J.L.6
  • 11
    • 34247646062 scopus 로고    scopus 로고
    • The anticancer drug imatinib induces cellular autophagy
    • PMID:17330103
    • Ertmer A, Huber V, Gilch S, Yoshimori T, Erfle V, Duyster J, et al. The anticancer drug imatinib induces cellular autophagy. Leukemia 2007; 21:936-42; PMID:17330103
    • (2007) Leukemia , vol.21 , pp. 936-942
    • Ertmer, A.1    Huber, V.2    Gilch, S.3    Yoshimori, T.4    Erfle, V.5    Duyster, J.6
  • 12
    • 66449122303 scopus 로고    scopus 로고
    • Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
    • PMID:19363292
    • Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, Ronchetti M, et al. Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest 2009; 119:1109-23; PMID:19363292; http://dx.doi.org/10. 1172/JCI35660
    • (2009) J Clin Invest , vol.119 , pp. 1109-1123
    • Bellodi, C.1    Lidonnici, M.R.2    Hamilton, A.3    Helgason, G.V.4    Soliera, A.R.5    Ronchetti, M.6
  • 13
    • 84864884448 scopus 로고    scopus 로고
    • Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells
    • PMID:22395361
    • Yu Y, Yang L, Zhao M, Zhu S, Kang R, Vernon P, et al. Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells. Leukemia 2012; 26:1752-60; PMID:22395361; http://dx.doi.org/10.1038/leu.2012.65
    • (2012) Leukemia , vol.26 , pp. 1752-1760
    • Yu, Y.1    Yang, L.2    Zhao, M.3    Zhu, S.4    Kang, R.5    Vernon, P.6
  • 14
    • 80052164677 scopus 로고    scopus 로고
    • Kill one bird with two stones: Potential efficacy of BCR-ABL and autophagy inhibition in CML
    • PMID:21693757
    • Helgason GV, Karvela M, Holyoake TL. Kill one bird with two stones: Potential efficacy of BCR-ABL and autophagy inhibition in CML. Blood 2011; 118:2035-43; PMID:21693757; http://dx.doi.org/10.1182/blood-2011-01-330621
    • (2011) Blood , vol.118 , pp. 2035-2043
    • Helgason, G.V.1    Karvela, M.2    Holyoake, T.L.3
  • 15
    • 79951505692 scopus 로고    scopus 로고
    • Inhibition of autophagy: A new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors
    • PMID:21250825
    • Calabretta B, Salomoni P. Inhibition of autophagy: A new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors. Leuk Lymphoma 2011; 52(Suppl 1):54-9; PMID:21250825; http://dx.doi.org/10.3109/10428194.2010.546913
    • (2011) Leuk Lymphoma , vol.52 , Issue.SUPPL. 1 , pp. 54-59
    • Calabretta, B.1    Salomoni, P.2
  • 16
    • 59249105259 scopus 로고    scopus 로고
    • Monitoring autophagy by electron microscopy in Mammalian cells
    • PMID:19200881
    • Ylä-Anttila P, Vihinen H, Jokitalo E, Eskelinen E-L. Monitoring autophagy by electron microscopy in Mammalian cells. Methods Enzymol 2009; 452:143-64; PMID:19200881; http://dx.doi.org/10.1016/S0076-6879(08)03610-0
    • (2009) Methods Enzymol , vol.452 , pp. 143-164
    • Ylä-Anttila, P.1    Vihinen, H.2    Jokitalo, E.3    Eskelinen, E.-L.4
  • 17
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • PMID:20144757
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 2010; 140:313-26; PMID:20144757; http://dx.doi.org/10.1016/j. cell.2010.01.028
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 18
    • 78349311964 scopus 로고    scopus 로고
    • Arsenic trioxide induces a beclin-1-independent autophagic pathway via modulation of SnoN/SkiL expression in ovarian carcinoma cells
    • PMID:20508647
    • Smith DM, Patel S, Raffoul F, Haller E, Mills GB, Nanjundan M. Arsenic trioxide induces a beclin-1-independent autophagic pathway via modulation of SnoN/SkiL expression in ovarian carcinoma cells. Cell Death Differ 2010; 17:1867-81; PMID:20508647; http://dx.doi.org/10.1038/cdd.2010.53
    • (2010) Cell Death Differ , vol.17 , pp. 1867-1881
    • Smith, D.M.1    Patel, S.2    Raffoul, F.3    Haller, E.4    Mills, G.B.5    Nanjundan, M.6
  • 19
    • 70349687405 scopus 로고    scopus 로고
    • Discovery of Atg5/Atg7-independent alternative macroautophagy
    • PMID:19794493
    • Nishida Y, Arakawa S, Fujitani K, Yamaguchi H, Mizuta T, Kanaseki T, et al. Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature 2009; 461:654-8; PMID:19794493; http://dx.doi.org/10.1038/nature08455
    • (2009) Nature , vol.461 , pp. 654-658
    • Nishida, Y.1    Arakawa, S.2    Fujitani, K.3    Yamaguchi, H.4    Mizuta, T.5    Kanaseki, T.6
  • 20
    • 79960585318 scopus 로고    scopus 로고
    • Ammonia-induced autophagy is independent of ULK1/ULK2 kinases
    • PMID:21690395
    • Cheong H, Lindsten T, Wu J, Lu C, Thompson CB. Ammonia-induced autophagy is independent of ULK1/ULK2 kinases. Proc Natl Acad Sci U S A 2011; 108:11121-6; PMID:21690395; http://dx.doi.org/10.1073/pnas.1107969108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 11121-11126
    • Cheong, H.1    Lindsten, T.2    Wu, J.3    Lu, C.4    Thompson, C.B.5
  • 21
    • 66349100518 scopus 로고    scopus 로고
    • P65/RelA modulates BECN1 transcription and autophagy
    • PMID:19289499
    • Copetti T, Bertoli C, Dalla E, Demarchi F, Schneider C. p65/RelA modulates BECN1 transcription and autophagy. Mol Cell Biol 2009; 29:2594-608; PMID:19289499; http://dx.doi.org/10.1128/MCB.01396-08
    • (2009) Mol Cell Biol , vol.29 , pp. 2594-2608
    • Copetti, T.1    Bertoli, C.2    Dalla, E.3    Demarchi, F.4    Schneider, C.5
  • 22
    • 32644449048 scopus 로고    scopus 로고
    • Acetylation of Stat1 modulates NF-kappaB activity
    • PMID:16481475
    • Krämer OH, Baus D, Knauer SK, Stein S, Jäger E, Stauber RH, et al. Acetylation of Stat1 modulates NF-kappaB activity. Genes Dev 2006; 20:473-85; PMID:16481475; http://dx.doi.org/10.1101/gad.364306
    • (2006) Genes Dev , vol.20 , pp. 473-485
    • Krämer, O.H.1    Baus, D.2    Knauer, S.K.3    Stein, S.4    Jäger, E.5    Stauber, R.H.6
  • 23
    • 79952628267 scopus 로고    scopus 로고
    • The beclin -1 network regulates autophagy and apoptosis
    • PMID:21311563
    • Kang R, Zeh HJ, Lotze MT, Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 2011; 18:571-80; PMID:21311563; http://dx.doi.org/10.1038/cdd.2010.191
    • (2011) Cell Death Differ , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 24
    • 26244431741 scopus 로고    scopus 로고
    • IFN-alpha enhances TNF-alpha-induced apoptosis through down-regulation of c-Myc protein expression in HL-60 cells
    • PMID:16270532
    • Nakashima A, Kumakura S, Mishima S, Ishikura H, Kobayashi S. IFN-alpha enhances TNF-alpha-induced apoptosis through down-regulation of c-Myc protein expression in HL-60 cells. J Exp Clin Cancer Res 2005; 24:447-56; PMID:16270532
    • (2005) J Exp Clin Cancer Res , vol.24 , pp. 447-456
    • Nakashima, A.1    Kumakura, S.2    Mishima, S.3    Ishikura, H.4    Kobayashi, S.5
  • 25
    • 75149140545 scopus 로고    scopus 로고
    • Resistance to IFN-alphainduced apoptosis is linked to a loss of STAT2
    • PMID:20068068
    • Romero-Weaver AL, Wang HW, Steen HC, Scarzello AJ, Hall VL, Sheikh F, et al. Resistance to IFN-alphainduced apoptosis is linked to a loss of STAT2. Mol Cancer Res 2010; 8:80-92; PMID:20068068; http://dx.doi.org/10.1158/1541-7786. MCR-08-0344
    • (2010) Mol Cancer Res , vol.8 , pp. 80-92
    • Romero-Weaver, A.L.1    Wang, H.W.2    Steen, H.C.3    Scarzello, A.J.4    Hall, V.L.5    Sheikh, F.6
  • 26
    • 84862295360 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy
    • PMID:22966490
    • Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012; 8:445-544; PMID:22966490; http://dx.doi.org/10.4161/auto.19496
    • (2012) Autophagy , vol.8 , pp. 445-544
    • Klionsky, D.J.1    Abdalla, F.C.2    Abeliovich, H.3    Abraham, R.T.4    Acevedo-Arozena, A.5    Adeli, K.6
  • 27
    • 10844219883 scopus 로고    scopus 로고
    • Role of tumor necrosis factor-related apoptosis-inducing ligand in interferon-induced apoptosis in human bladder cancer cells
    • PMID:15604261
    • Papageorgiou A, Lashinger L, Millikan R, Grossman HB, Benedict W, Dinney CP, et al. Role of tumor necrosis factor-related apoptosis-inducing ligand in interferon-induced apoptosis in human bladder cancer cells. Cancer Res 2004; 64:8973-9; PMID:15604261; http://dx.doi.org/10.1158/0008-5472.CAN-04-1909
    • (2004) Cancer Res , vol.64 , pp. 8973-8979
    • Papageorgiou, A.1    Lashinger, L.2    Millikan, R.3    Grossman, H.B.4    Benedict, W.5    Dinney, C.P.6
  • 28
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • PMID:9727492
    • Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998; 94:491-501; PMID:9727492; http://dx.doi.org/10.1016/S0092-8674(00)81590-1
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.J.3    Yuan, J.4
  • 29
    • 36749069393 scopus 로고    scopus 로고
    • Interferons at age 50: Past, current and future impact on biomedicine
    • PMID:18049472
    • Borden EC, Sen GC, Uze G, Silverman RH, Ransohoff RM, Foster GR, et al. Interferons at age 50: Past, current and future impact on biomedicine. Nat Rev Drug Discov 2007; 6:975-90; PMID:18049472; http://dx.doi.org/10.1038/nrd2422
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 975-990
    • Borden, E.C.1    Sen, G.C.2    Uze, G.3    Silverman, R.H.4    Ransohoff, R.M.5    Foster, G.R.6
  • 30
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • PMID:15607973
    • Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, Deretic V. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004; 119:753-66; PMID:15607973; http://dx.doi.org/10.1016/j.cell.2004.11.038
    • (2004) Cell , vol.119 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5    Deretic, V.6
  • 31
    • 77956508417 scopus 로고    scopus 로고
    • Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation
    • PMID:20592027
    • Chang YP, Tsai CC, Huang WC, Wang CY, Chen CL, Lin YS, et al. Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation. J Biol Chem 2010; 285:28715-22; PMID:20592027; http://dx.doi.org/10.1074/jbc. M110.133355
    • (2010) J Biol Chem , vol.285 , pp. 28715-28722
    • Chang, Y.P.1    Tsai, C.C.2    Huang, W.C.3    Wang, C.Y.4    Chen, C.L.5    Lin, Y.S.6
  • 32
    • 77954814350 scopus 로고    scopus 로고
    • Autophagy is induced by adenoviral-mediated interferon alpha treatment in interferon resistant bladder cancer and normal urothelial cells as a cell death protective mechanism but not by the bystander factors produced
    • PMID:20489789
    • Zhang XQ, Dunner K Jr., Benedict WF. Autophagy is induced by adenoviral-mediated interferon alpha treatment in interferon resistant bladder cancer and normal urothelial cells as a cell death protective mechanism but not by the bystander factors produced. Cancer Gene Ther 2010; 17:579-84; PMID:20489789; http://dx.doi.org/10.1038/cgt.2010.14
    • (2010) Cancer Gene Ther , vol.17 , pp. 579-584
    • Zhang, X.Q.1    Dunner Jr., K.2    Benedict, W.F.3
  • 33
    • 84861865743 scopus 로고    scopus 로고
    • Cell-mediated autophagy promotes cancer cell survival
    • PMID:22505650
    • Buchser WJ, Laskow TC, Pavlik PJ, Lin HM, Lotze MT. Cell-mediated autophagy promotes cancer cell survival. Cancer Res 2012; 72:2970-9; PMID:22505650; http://dx.doi.org/10.1158/0008-5472.CAN-11-3396.
    • (2012) Cancer Res , vol.72 , pp. 2970-2979
    • Buchser, W.J.1    Laskow, T.C.2    Pavlik, P.J.3    Lin, H.M.4    Lotze, M.T.5
  • 34
    • 33947134377 scopus 로고    scopus 로고
    • Autophagy-dependent viral recognition by plasmacytoid dendritic cells
    • PMID:17272685
    • Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 2007; 315:1398-401; PMID:17272685; http://dx.doi.org/10.1126/science.1136880
    • (2007) Science , vol.315 , pp. 1398-1401
    • Lee, H.K.1    Lund, J.M.2    Ramanathan, B.3    Mizushima, N.4    Iwasaki, A.5
  • 35
    • 77957957189 scopus 로고    scopus 로고
    • T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation
    • PMID:20951945
    • Feng H, Stachura DL, White RM, Gutierrez A, Zhang L, Sanda T, et al. T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer Cell 2010; 18:353-66; PMID:20951945; http://dx.doi.org/10.1016/j.ccr.2010.09.009
    • (2010) Cancer Cell , vol.18 , pp. 353-366
    • Feng, H.1    Stachura, D.L.2    White, R.M.3    Gutierrez, A.4    Zhang, L.5    Sanda, T.6
  • 36
    • 33846794896 scopus 로고    scopus 로고
    • Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
    • PMID:17235397
    • Amaravadi RK, Yu D, Lum JJ, Bui T, Christophorou MA, Evan GI, et al. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J Clin Invest 2007; 117:326-36; PMID:17235397; http://dx.doi.org/ 10.1172/JCI28833
    • (2007) J Clin Invest , vol.117 , pp. 326-336
    • Amaravadi, R.K.1    Yu, D.2    Lum, J.J.3    Bui, T.4    Christophorou, M.A.5    Evan, G.I.6
  • 37
    • 80052164677 scopus 로고    scopus 로고
    • Kill one bird with two stones: Potential efficacy of BCR-ABL and autophagy inhibition in CML
    • PMID:21693757
    • Helgason GV, Karvela M, Holyoake TL. Kill one bird with two stones: Potential efficacy of BCR-ABL and autophagy inhibition in CML. Blood 2011; 118:2035-43; PMID:21693757; http://dx.doi.org/10.1182/blood-2011-01-330621
    • (2011) Blood , vol.118 , pp. 2035-2043
    • Helgason, G.V.1    Karvela, M.2    Holyoake, T.L.3
  • 38
    • 34347394714 scopus 로고    scopus 로고
    • Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance
    • PMID:17363733
    • Carew JS, Nawrocki ST, Kahue CN, Zhang H, Yang C, Chung L, et al. Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance. Blood 2007; 110:313-22; PMID:17363733; http://dx.doi.org/10.1182/blood-2006-10-050260
    • (2007) Blood , vol.110 , pp. 313-322
    • Carew, J.S.1    Nawrocki, S.T.2    Kahue, C.N.3    Zhang, H.4    Yang, C.5    Chung, L.6
  • 39
    • 54049135563 scopus 로고    scopus 로고
    • The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias
    • PMID:18617896
    • Kamitsuji Y, Kuroda J, Kimura S, Toyokuni S, Watanabe K, Ashihara E, et al. The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias. Cell Death Differ 2008; 15:1712-22; PMID:18617896; http://dx.doi.org/10.1038/cdd.2008.107
    • (2008) Cell Death Differ , vol.15 , pp. 1712-1722
    • Kamitsuji, Y.1    Kuroda, J.2    Kimura, S.3    Toyokuni, S.4    Watanabe, K.5    Ashihara, E.6
  • 40
    • 58149097087 scopus 로고    scopus 로고
    • Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal components
    • PMID:18945674
    • Yogalingam G, Pendergast AM. Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal components. J Biol Chem 2008; 283:35941-53; PMID:18945674; http://dx.doi.org/10.1074/jbc. M804543200
    • (2008) J Biol Chem , vol.283 , pp. 35941-35953
    • Yogalingam, G.1    Pendergast, A.M.2
  • 41
    • 77956386515 scopus 로고    scopus 로고
    • Endogenous HMGB1 regulates autophagy
    • PMID:20819940
    • Tang D, Kang R, Livesey KM, Cheh CW, Farkas A, Loughran P, et al. Endogenous HMGB1 regulates autophagy. J Cell Biol 2010; 190:881-92; PMID:20819940; http://dx.doi.org/10.1083/jcb.200911078
    • (2010) J Cell Biol , vol.190 , pp. 881-892
    • Tang, D.1    Kang, R.2    Livesey, K.M.3    Cheh, C.W.4    Farkas, A.5    Loughran, P.6
  • 42
    • 78651286142 scopus 로고    scopus 로고
    • HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells
    • PMID:20927132
    • Liu L, Yang M, Kang R, Wang Z, Zhao Y, Yu Y, et al. HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells. Leukemia 2011; 25:23-31; PMID:20927132; http://dx.doi.org/10.1038/leu.2010.225
    • (2011) Leukemia , vol.25 , pp. 23-31
    • Liu, L.1    Yang, M.2    Kang, R.3    Wang, Z.4    Zhao, Y.5    Yu, Y.6
  • 43
    • 77951171023 scopus 로고    scopus 로고
    • Induction of autophagydependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance
    • PMID:20200450
    • Bonapace L, Bornhauser BC, Schmitz M, Cario G, Ziegler U, Niggli FK, et al. Induction of autophagydependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance. J Clin Invest 2010; 120:1310-23; PMID:20200450; http://dx.doi.org/10.1172/JCI39987
    • (2010) J Clin Invest , vol.120 , pp. 1310-1323
    • Bonapace, L.1    Bornhauser, B.C.2    Schmitz, M.3    Cario, G.4    Ziegler, U.5    Niggli, F.K.6
  • 44
    • 76249124608 scopus 로고    scopus 로고
    • Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation
    • PMID:20103647
    • Puissant A, Robert G, Fenouille N, Luciano F, Cassuto JP, Raynaud S, et al. Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. Cancer Res 2010; 70:1042-52; PMID:20103647; http://dx.doi.org/10.1158/0008-5472.CAN-09-3537
    • (2010) Cancer Res , vol.70 , pp. 1042-1052
    • Puissant, A.1    Robert, G.2    Fenouille, N.3    Luciano, F.4    Cassuto, J.P.5    Raynaud, S.6
  • 45
    • 34547108380 scopus 로고    scopus 로고
    • JAK-STAT signaling: From interferons to cytokines
    • PMID:17502367
    • Schindler C, Levy DE, Decker T. JAK-STAT signaling: From interferons to cytokines. J Biol Chem 2007; 282:20059-63; PMID:17502367; http://dx.doi.org/10. 1074/jbc.R700016200
    • (2007) J Biol Chem , vol.282 , pp. 20059-20063
    • Schindler, C.1    Levy, D.E.2    Decker, T.3
  • 47
    • 77957654940 scopus 로고    scopus 로고
    • Autophagic degradation of active caspase-8: A crosstalk mechanism between autophagy and apoptosis
    • PMID:20724831
    • Hou W, Han J, Lu C, Goldstein LA, Rabinowich H. Autophagic degradation of active caspase-8: A crosstalk mechanism between autophagy and apoptosis. Autophagy 2010; 6:891-900; PMID:20724831; http://dx.doi.org/10.4161/auto.6.7. 13038
    • (2010) Autophagy , vol.6 , pp. 891-900
    • Hou, W.1    Han, J.2    Lu, C.3    Goldstein, L.A.4    Rabinowich, H.5
  • 48
    • 83655190818 scopus 로고    scopus 로고
    • HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cells
    • PMID:21944254
    • Zhao M, Yang M, Yang L, Yu Y, Xie M, Zhu S, et al. HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cells. BMB Rep 2011; 44:601-6; PMID:21944254; http://dx.doi.org/10.5483/BMBRep.2011.44.9.601
    • (2011) BMB Rep , vol.44 , pp. 601-606
    • Zhao, M.1    Yang, M.2    Yang, L.3    Yu, Y.4    Xie, M.5    Zhu, S.6
  • 49
    • 77957106729 scopus 로고    scopus 로고
    • HMGB1 release and redox regulates autophagy and apoptosis in cancer cells
    • PMID:20622903
    • Tang D, Kang R, Cheh CW, Livesey KM, Liang X, Schapiro NE, et al. HMGB1 release and redox regulates autophagy and apoptosis in cancer cells. Oncogene 2010; 29:5299-310; PMID:20622903; http://dx.doi.org/10.1038/onc.2010.261
    • (2010) Oncogene , vol.29 , pp. 5299-5310
    • Tang, D.1    Kang, R.2    Cheh, C.W.3    Livesey, K.M.4    Liang, X.5    Schapiro, N.E.6
  • 50
    • 79953666792 scopus 로고    scopus 로고
    • Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein
    • PMID:21187718
    • Wang Z, Cao L, Kang R, Yang M, Liu L, Zhao Y, et al. Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein. Autophagy 2011; 7:401-11; PMID:21187718; http://dx.doi.org/10.4161/auto.7.4.14397
    • (2011) Autophagy , vol.7 , pp. 401-411
    • Wang, Z.1    Cao, L.2    Kang, R.3    Yang, M.4    Liu, L.5    Zhao, Y.6
  • 51
    • 74249095142 scopus 로고    scopus 로고
    • WAVE1 regulates Bcl-2 localization and phosphorylation in leukemia cells
    • PMID:19890377
    • Kang R, Tang D, Yu Y, Wang Z, Hu T, Wang H, et al. WAVE1 regulates Bcl-2 localization and phosphorylation in leukemia cells. Leukemia 2010; 24:177-86; PMID:19890377; http://dx.doi.org/10.1038/leu.2009.224
    • (2010) Leukemia , vol.24 , pp. 177-186
    • Kang, R.1    Tang, D.2    Yu, Y.3    Wang, Z.4    Hu, T.5    Wang, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.