From Genomics to Gene Therapy: Induced Pluripotent Stem Cells Meet Genome Editing

Annual Review of Genetics

Volumn 49, Issue , 2015, Pages 47-70

  Hotta, Akitsu ^a,b   Yamanaka, Shinya ^a,b,c  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

Author keywords

CRISPR Cas9; Genetic correction; Pluripotent stem cells; Programmable nuclease; TALEN

Indexed keywords

CRISPR ASSOCIATED PROTEIN; MEGANUCLEASE; NUCLEASE; OLIGONUCLEOTIDE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; VIRUS VECTOR; ZINC FINGER NUCLEASE;

ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CELL DIFFERENTIATION; CELL MATURATION; CHROMOSOME DELETION; CHROMOSOME INVERSION; DONOR SELECTION; EMBRYONIC STEM CELL; GENE IDENTIFICATION; GENE TARGETING; GENE THERAPY; GENETIC ENGINEERING; GENETIC MANIPULATION; GENOME; GENOMICS; HUMAN; LARGE SCALE PRODUCTION; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; ANIMAL; CRISPR CAS SYSTEM; GENE VECTOR; INDUCED PLURIPOTENT STEM CELL; MOUSE; PHYSIOLOGY; PROCEDURES;

ANIMALS; CHROMOSOME DELETION; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CRISPR-CAS SYSTEMS; GENE TARGETING; GENETIC ENGINEERING; GENETIC THERAPY; GENETIC VECTORS; GENOMICS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE;

EID: 84948760948     PISSN: 00664197     EISSN: 15452948     Source Type: Book Series    
DOI: 10.1146/annurev-genet-112414-054926     Document Type: Article

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