-
1
-
-
18944373328
-
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
-
DOI 10.1038/nature03556
-
Urnov FD, Miller JC, Lee YL, Beausejour CM, Rock JM, et al. (2005) Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 435: 646-651. (Pubitemid 40825505)
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 646-651
-
-
Urnov, F.D.1
Miller, J.C.2
Lee, Y.-L.3
Beausejour, C.M.4
Rock, J.M.5
Augustus, S.6
Jamieson, A.C.7
Porteus, M.H.8
Gregory, P.D.9
Holmes, M.C.10
-
2
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong L, Ran FA, Cox D, Lin S, Barretto R, et al. (2013) Multiplex genome engineering using CRISPR/Cas systems. Science 339: 819-823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
-
3
-
-
84877707375
-
Onestep generation of mice carrying mutations in multiple genes by CRISPR/Casmediated genome engineering
-
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, et al. (2013) Onestep generation of mice carrying mutations in multiple genes by CRISPR/Casmediated genome engineering. Cell 153: 910-918.
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
-
4
-
-
84873733109
-
A TALEN genome-editing system for generating human stem cell-based disease models
-
Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, et al. (2013) A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell 12: 238-251.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 238-251
-
-
Ding, Q.1
Lee, Y.K.2
Schaefer, E.A.3
Peters, D.T.4
Veres, A.5
-
5
-
-
79960064013
-
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
-
Cermak T, Doyle EL, Christian M, Wang L, Zhang Y, et al. (2011) Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Res 39: e82.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Cermak, T.1
Doyle, E.L.2
Christian, M.3
Wang, L.4
Zhang, Y.5
-
6
-
-
84860747716
-
FLASH assembly of TALENs for high-throughput genome editing
-
Reyon D, Tsai SQ, Khayter C, Foden JA, Sander JD, et al. (2012) FLASH assembly of TALENs for high-throughput genome editing. Nat Biotechnol 30: 460-465.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 460-465
-
-
Reyon, D.1
Tsai, S.Q.2
Khayter, C.3
Foden, J.A.4
Sander, J.D.5
-
7
-
-
80053039555
-
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
-
Mussolino C, Morbitzer R, Lutge F, Dannemann N, Lahaye T, et al. (2011) A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. Nucleic Acids Res 39: 9283-9293.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 9283-9293
-
-
Mussolino, C.1
Morbitzer, R.2
Lutge, F.3
Dannemann, N.4
Lahaye, T.5
-
8
-
-
79960836456
-
Genetic engineering of human pluripotent cells using TALE nucleases
-
Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, et al. (2011) Genetic engineering of human pluripotent cells using TALE nucleases. Nat Biotechnol 29: 731-734.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 731-734
-
-
Hockemeyer, D.1
Wang, H.2
Kiani, S.3
Lai, C.S.4
Gao, Q.5
-
9
-
-
84884165315
-
DNA targeting specificity of RNA-guided Cas9 nucleases
-
Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, et al. (2013) DNA targeting specificity of RNA-guided Cas9 nucleases. Nat Biotechnol 31: 827-832.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 827-832
-
-
Hsu, P.D.1
Scott, D.A.2
Weinstein, J.A.3
Ran, F.A.4
Konermann, S.5
-
10
-
-
84880570576
-
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
-
Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, et al. (2013) High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat Biotechnol 31: 822-826.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 822-826
-
-
Fu, Y.1
Foden, J.A.2
Khayter, C.3
Maeder, M.L.4
Reyon, D.5
-
11
-
-
84891710947
-
Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
-
Cho SW, Kim S, Kim Y, Kweon J, Kim HS, et al. (2013) Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. Genome Res.
-
(2013)
Genome Res
-
-
Cho, S.W.1
Kim, S.2
Kim, Y.3
Kweon, J.4
Kim, H.S.5
-
12
-
-
84861170955
-
A transcription activator-like effector toolbox for genome engineering
-
Sanjana NE, Cong L, Zhou Y, Cunniff MM, Feng G, et al. (2012) A transcription activator-like effector toolbox for genome engineering. Nat Protoc 7: 171-192.
-
(2012)
Nat Protoc
, vol.7
, pp. 171-192
-
-
Sanjana, N.E.1
Cong, L.2
Zhou, Y.3
Cunniff, M.M.4
Feng, G.5
-
13
-
-
84878580410
-
TALEN-based gene correction for epidermolysis bullosa
-
Osborn MJ, Starker CG, McElroy AN, Webber BR, Riddle MJ, et al. (2013) TALEN-based gene correction for epidermolysis bullosa. Mol Ther 21: 1151-1159.
-
(2013)
Mol Ther
, vol.21
, pp. 1151-1159
-
-
Osborn, M.J.1
Starker, C.G.2
McElroy, A.N.3
Webber, B.R.4
Riddle, M.J.5
-
14
-
-
79960034141
-
Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes
-
Li T, Huang S, Zhao X, Wright DA, Carpenter S, et al. (2011) Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes. Nucleic Acids Res 39: 6315-6325.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 6315-6325
-
-
Li, T.1
Huang, S.2
Zhao, X.3
Wright, D.A.4
Carpenter, S.5
-
15
-
-
78951479577
-
Targeting DNA double-strand breaks with TAL effector nucleases
-
Christian M, Cermak T, Doyle EL, Schmidt C, Zhang F, et al. (2010) Targeting DNA double-strand breaks with TAL effector nucleases. Genetics 186: 757-761.
-
(2010)
Genetics
, vol.186
, pp. 757-761
-
-
Christian, M.1
Cermak, T.2
Doyle, E.L.3
Schmidt, C.4
Zhang, F.5
-
16
-
-
84857029597
-
The crystal structure of TAL effector PthXo1 bound to its DNA target
-
Mak AN, Bradley P, Cernadas RA, Bogdanove AJ, Stoddard BL (2012) The crystal structure of TAL effector PthXo1 bound to its DNA target. Science 335: 716-719.
-
(2012)
Science
, vol.335
, pp. 716-719
-
-
Mak, A.N.1
Bradley, P.2
Cernadas, R.A.3
Bogdanove, A.J.4
Stoddard, B.L.5
-
17
-
-
84857032466
-
Structural basis for sequence-specific recognition of DNA by TAL effectors
-
Deng D, Yan C, Pan X, Mahfouz M, Wang J, et al. (2012) Structural basis for sequence-specific recognition of DNA by TAL effectors. Science 335: 720-723.
-
(2012)
Science
, vol.335
, pp. 720-723
-
-
Deng, D.1
Yan, C.2
Pan, X.3
Mahfouz, M.4
Wang, J.5
-
19
-
-
78651270582
-
TAL nucleases (TALNs): Hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
-
Li T, Huang S, Jiang WZ, Wright D, Spalding MH, et al. (2010) TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain. Nucleic Acids Res 39: 359-372.
-
(2010)
Nucleic Acids Res
, vol.39
, pp. 359-372
-
-
Li, T.1
Huang, S.2
Jiang, W.Z.3
Wright, D.4
Spalding, M.H.5
-
20
-
-
79952302385
-
De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
-
Mahfouz MM, Li L, Shamimuzzaman M, Wibowo A, Fang X, et al. (2011) De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks. Proc Natl Acad Sci U S A 108: 2623-2628.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 2623-2628
-
-
Mahfouz, M.M.1
Li, L.2
Shamimuzzaman, M.3
Wibowo, A.4
Fang, X.5
-
21
-
-
80052292973
-
Highfrequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases
-
Chen F, Pruett-Miller SM, Huang Y, Gjoka M, Duda K, et al. (2011) Highfrequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases. Nat Methods 8: 753-755.
-
(2011)
Nat Methods
, vol.8
, pp. 753-755
-
-
Chen, F.1
Pruett-Miller, S.M.2
Huang, Y.3
Gjoka, M.4
Duda, K.5
-
22
-
-
84868342049
-
In vivo genome editing using a high-efficiency TALEN system
-
Bedell VM, Wang Y, Campbell JM, Poshusta TL, Starker CG, et al. (2012) In vivo genome editing using a high-efficiency TALEN system. Nature 491: 114-118.
-
(2012)
Nature
, vol.491
, pp. 114-118
-
-
Bedell, V.M.1
Wang, Y.2
Campbell, J.M.3
Poshusta, T.L.4
Starker, C.G.5
-
23
-
-
84867911474
-
Efficient TALEN-mediated gene knockout in livestock
-
Carlson DF, Tan W, Lillico SG, Stverakova D, Proudfoot C, et al. (2012) Efficient TALEN-mediated gene knockout in livestock. Proc Natl Acad Sci U S A 109: 17382-17387.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 17382-17387
-
-
Carlson, D.F.1
Tan, W.2
Lillico, S.G.3
Stverakova, D.4
Proudfoot, C.5
-
24
-
-
79961185942
-
Heritable gene targeting in zebrafish using customized TALENs
-
Huang P, Xiao A, Zhou M, Zhu Z, Lin S, et al. (2011) Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol 29: 699-700.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 699-700
-
-
Huang, P.1
Xiao, A.2
Zhou, M.3
Zhu, Z.4
Lin, S.5
-
25
-
-
79961192836
-
Targeted gene disruption in somatic zebrafish cells using engineered TALENs
-
Sander JD, Cade L, Khayter C, Reyon D, Peterson RT, et al. (2011) Targeted gene disruption in somatic zebrafish cells using engineered TALENs. Nat Biotechnol 29: 697-698.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 697-698
-
-
Sander, J.D.1
Cade, L.2
Khayter, C.3
Reyon, D.4
Peterson, R.T.5
-
26
-
-
84863100905
-
Rapid and costeffective gene targeting in rat embryonic stem cells by TALENs
-
Tong C, Huang G, Ashton C, Wu H, Yan H, et al. (2012) Rapid and costeffective gene targeting in rat embryonic stem cells by TALENs. J Genet Genomics 39: 275-280.
-
(2012)
J Genet Genomics
, vol.39
, pp. 275-280
-
-
Tong, C.1
Huang, G.2
Ashton, C.3
Wu, H.4
Yan, H.5
-
27
-
-
84874628805
-
Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides
-
Wefers B, Meyer M, Ortiz O, Hrabe de Angelis M, Hansen J, et al. (2013) Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides. Proc Natl Acad Sci U S A 110: 3782-3787.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 3782-3787
-
-
Wefers, B.1
Meyer, M.2
Ortiz, O.3
Hrabe De Angelis, M.4
Hansen, J.5
-
28
-
-
84867904873
-
Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)
-
Lei Y, Guo X, Liu Y, Cao Y, Deng Y, et al. (2012) Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs). Proc Natl Acad Sci U S A 109: 17484-17489.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 17484-17489
-
-
Lei, Y.1
Guo, X.2
Liu, Y.3
Cao, Y.4
Deng, Y.5
-
29
-
-
84877105430
-
Targeting human microRNA genes using engineered Tal-effector nucleases (TALENs)
-
Hu R, Wallace J, Dahlem TJ, Grunwald DJ, O'Connell RM (2013) Targeting human microRNA genes using engineered Tal-effector nucleases (TALENs). PLoS One 8: e63074.
-
(2013)
PLoS One
, vol.8
-
-
Hu, R.1
Wallace, J.2
Dahlem, T.J.3
Grunwald, D.J.4
O'connell, R.M.5
-
30
-
-
84885703560
-
Targeted Gene Deletion of miRNAs in Mice by TALEN System
-
Takada S, Sato T, Ito Y, Yamashita S, Kato T, et al. (2013) Targeted Gene Deletion of miRNAs in Mice by TALEN System. PLoS One 8: e76004.
-
(2013)
PLoS One
, vol.8
-
-
Takada, S.1
Sato, T.2
Ito, Y.3
Yamashita, S.4
Kato, T.5
-
31
-
-
84890212376
-
TALEN-based knockout library for human microRNAs
-
Kim YK, Wee G, Park J, Kim J, Baek D, et al. (2013) TALEN-based knockout library for human microRNAs. Nat Struct Mol Biol.
-
(2013)
Nat Struct Mol Biol
-
-
Kim, Y.K.1
Wee, G.2
Park, J.3
Kim, J.4
Baek, D.5
-
32
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan ME, Jasin M (2010) Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol 11: 196-207.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
33
-
-
84864475122
-
TAL effector-nucleotide targeter (TALE-NT) 2.0: Tools for TAL effector design and target prediction
-
Doyle EL, Booher NJ, Standage DS, Voytas DF, Brendel VP, et al. (2012) TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction. Nucleic Acids Res 40: W117-122.
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Doyle, E.L.1
Booher, N.J.2
Standage, D.S.3
Voytas, D.F.4
Brendel, V.P.5
-
34
-
-
77749279749
-
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
-
Hu BY, Weick JP, Yu J, Ma LX, Zhang XQ, et al. (2010) Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc Natl Acad Sci U S A 107: 4335-4340.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4335-4340
-
-
Hu, B.Y.1
Weick, J.P.2
Yu, J.3
Ma, L.X.4
Zhang, X.Q.5
-
35
-
-
18244397746
-
Quantification of MYCN, DDX1, and NAG gene copy number in neuroblastoma using a real-time quantitative PCR assay
-
DOI 10.1038/modpathol.3880508
-
De Preter K, Speleman F, Combaret V, Lunec J, Laureys G, et al. (2002) Quantification of MYCN, DDX1, and NAG gene copy number in neuroblastoma using a real-time quantitative PCR assay. Mod Pathol 15: 159-166. (Pubitemid 34171326)
-
(2002)
Modern Pathology
, vol.15
, Issue.2
, pp. 159-166
-
-
De Preter, K.1
Speleman, F.2
Combaret, V.3
Lunec, J.4
Laureys, G.5
Eussen, B.H.J.6
Francotte, N.7
Board, J.8
Pearson, A.D.J.9
De Paepe, A.10
Van Roy, N.11
Vandesompele, J.12
-
36
-
-
72149110399
-
Breaking the code of DNA binding specificity of TAL-type III effectors
-
Boch J, Scholze H, Schornack S, Landgraf A, Hahn S, et al. (2009) Breaking the code of DNA binding specificity of TAL-type III effectors. Science 326: 1509-1512.
-
(2009)
Science
, vol.326
, pp. 1509-1512
-
-
Boch, J.1
Scholze, H.2
Schornack, S.3
Landgraf, A.4
Hahn, S.5
-
37
-
-
72149090954
-
A simple cipher governs DNA recognition by TAL effectors
-
Moscou MJ, Bogdanove AJ (2009) A simple cipher governs DNA recognition by TAL effectors. Science 326: 1501.
-
(2009)
Science
, vol.326
, pp. 1501
-
-
Moscou, M.J.1
Bogdanove, A.J.2
-
38
-
-
55249102500
-
MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium
-
Shibata M, Kurokawa D, Nakao H, Ohmura T, Aizawa S (2008) MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium. J Neurosci 28: 10415-10421.
-
(2008)
J Neurosci
, vol.28
, pp. 10415-10421
-
-
Shibata, M.1
Kurokawa, D.2
Nakao, H.3
Ohmura, T.4
Aizawa, S.5
-
39
-
-
44349088251
-
MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary
-
DOI 10.1038/nn.2115, PII NN2115
-
Leucht C, Stigloher C, Wizenmann A, Klafke R, Folchert A, et al. (2008) MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary. Nat Neurosci 11: 641-648. (Pubitemid 351748112)
-
(2008)
Nature Neuroscience
, vol.11
, Issue.6
, pp. 641-648
-
-
Leucht, C.1
Stigloher, C.2
Wizenmann, A.3
Klafke, R.4
Folchert, A.5
Bally-Cuif, L.6
-
40
-
-
77949895548
-
MicroRNA-9 controls a migratory mechanism in human neural progenitor cells
-
Uchida N (2010) MicroRNA-9 controls a migratory mechanism in human neural progenitor cells. Cell Stem Cell 6: 294-296.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 294-296
-
-
Uchida, N.1
-
41
-
-
84860284308
-
MicroRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons
-
Dajas-Bailador F, Bonev B, Garcez P, Stanley P, Guillemot F, et al. (2012) microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons. Nat Neurosci 15: 697-699.
-
(2012)
Nat Neurosci
, vol.15
, pp. 697-699
-
-
Dajas-Bailador, F.1
Bonev, B.2
Garcez, P.3
Stanley, P.4
Guillemot, F.5
-
42
-
-
77949903674
-
MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors
-
Delaloy C, Liu L, Lee JA, Su H, Shen F, et al. (2010) MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. Cell Stem Cell 6: 323-335.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 323-335
-
-
Delaloy, C.1
Liu, L.2
Lee, J.A.3
Su, H.4
Shen, F.5
-
43
-
-
79960075244
-
MicroRNA-9: Functional evolution of a conserved small regulatory RNA
-
Yuva-Aydemir Y, Simkin A, Gascon E, Gao FB (2011) MicroRNA-9: functional evolution of a conserved small regulatory RNA. RNA Biol 8: 557-564.
-
(2011)
RNA Biol
, vol.8
, pp. 557-564
-
-
Yuva-Aydemir, Y.1
Simkin, A.2
Gascon, E.3
Gao, F.B.4
-
44
-
-
79952267171
-
MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors
-
Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S (2011) MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci 31: 3407-3422.
-
(2011)
J Neurosci
, vol.31
, pp. 3407-3422
-
-
Shibata, M.1
Nakao, H.2
Kiyonari, H.3
Abe, T.4
Aizawa, S.5
-
45
-
-
78649832226
-
A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation
-
Laneve P, Gioia U, Andriotto A, Moretti F, Bozzoni I, et al. (2010) A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation. Nucleic Acids Res 38: 6895-6905.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 6895-6905
-
-
Laneve, P.1
Gioia, U.2
Andriotto, A.3
Moretti, F.4
Bozzoni, I.5
-
46
-
-
84862224590
-
Homologous chromosomes make contact at the sites of double-strand breaks in genes in somatic G0/G1-phase human cells
-
Gandhi M, Evdokimova VN, K TC, Nikiforova MN, Kelly LM, et al. (2012) Homologous chromosomes make contact at the sites of double-strand breaks in genes in somatic G0/G1-phase human cells. Proc Natl Acad Sci U S A 109: 9454-9459.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 9454-9459
-
-
Gandhi, M.1
Evdokimova, V.N.2
Nikiforova, M.N.3
Kelly, L.M.4
-
47
-
-
0032535036
-
Double-strand break repair by interchromosomal recombination: Suppression of chromosomal translocations
-
Richardson C, Moynahan ME, Jasin M (1998) Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations. Genes Dev 12: 3831-3842. (Pubitemid 29024846)
-
(1998)
Genes and Development
, vol.12
, Issue.24
, pp. 3831-3842
-
-
Richardson, C.1
Moynahan, M.E.2
Jasin, M.3
-
48
-
-
0024769286
-
Homologous recombination involving small single-stranded oligonucleotides in human cells
-
Campbell CR, Keown W, Lowe L, Kirschling D, Kucherlapati R (1989) Homologous recombination involving small single-stranded oligonucleotides in human cells. New Biol 1: 223-227.
-
(1989)
New Biol
, vol.1
, pp. 223-227
-
-
Campbell, C.R.1
Keown, W.2
Lowe, L.3
Kirschling, D.4
Kucherlapati, R.5
-
49
-
-
32844470294
-
Physical incorporation of a single-stranded oligodeoxynucleotide during targeted repair of a human chromosomal locus
-
DOI 10.1002/jgm.828
-
Radecke S, Radecke F, Peter I, Schwarz K (2006) Physical incorporation of a single-stranded oligodeoxynucleotide during targeted repair of a human chromosomal locus. J Gene Med 8: 217-228. (Pubitemid 43250702)
-
(2006)
Journal of Gene Medicine
, vol.8
, Issue.2
, pp. 217-228
-
-
Radecke, S.1
Radecke, F.2
Peter, I.3
Schwarz, K.4
-
50
-
-
65349090679
-
Use of internally nuclease-protected single-strand DNA oligonucleotides and silencing of the mismatch repair protein, MSH2, enhances the replication of corrected cells following gene editing
-
Papaioannou I, Disterer P, Owen JS (2009) Use of internally nuclease-protected single-strand DNA oligonucleotides and silencing of the mismatch repair protein, MSH2, enhances the replication of corrected cells following gene editing. J Gene Med 11: 267-274.
-
(2009)
J Gene Med
, vol.11
, pp. 267-274
-
-
Papaioannou, I.1
Disterer, P.2
Owen, J.S.3
-
51
-
-
78651275193
-
Subtle gene modification in mouse ES cells: Evidence for incorporation of unmodified oligonucleotides without induction of DNA damage
-
Aarts M, te Riele H (2010) Subtle gene modification in mouse ES cells: evidence for incorporation of unmodified oligonucleotides without induction of DNA damage. Nucleic Acids Res 38: 6956-6967.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 6956-6967
-
-
Aarts, M.1
Te Riele, H.2
-
52
-
-
47649120455
-
Oligonucleotide-mediated gene targeting in human hepatocytes: Implications of mismatch repair
-
DOI 10.1089/oli.2008.0120
-
Igoucheva O, Alexeev V, Anni H, Rubin E (2008) Oligonucleotide-mediated gene targeting in human hepatocytes: implications of mismatch repair. Oligonucleotides 18: 111-122. (Pubitemid 352019750)
-
(2008)
Oligonucleotides
, vol.18
, Issue.2
, pp. 111-122
-
-
Igoucheva, O.1
Alexeev, V.2
Anni, H.3
Rubin, E.4
-
53
-
-
33645800191
-
Involvement of ERCC1/ XPF and XPG in oligodeoxynucleotide-directed gene modification
-
Igoucheva O, Alexeev V, Scharer O, Yoon K (2006) Involvement of ERCC1/ XPF and XPG in oligodeoxynucleotide-directed gene modification. Oligonucleotides 16: 94-104.
-
(2006)
Oligonucleotides
, vol.16
, pp. 94-104
-
-
Igoucheva, O.1
Alexeev, V.2
Scharer, O.3
Yoon, K.4
-
54
-
-
22444445110
-
Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAs
-
DOI 10.1093/nar/gki686
-
Andrieu-Soler C, Casas M, Faussat AM, Gandolphe C, Doat M, et al. (2005) Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAs. Nucleic Acids Res 33: 3733-3742. (Pubitemid 41418542)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.12
, pp. 3733-3742
-
-
Andrieu-Soler, C.1
Casas, M.2
Faussat, A.-M.3
Gandolphe, C.4
Doat, M.5
Tempe, D.6
Giovannangeli, C.7
Behar-Cohen, F.8
Concordet, J.-P.9
-
55
-
-
84863201964
-
Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers
-
Bultmann S, Morbitzer R, Schmidt CS, Thanisch K, Spada F, et al. (2012) Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers. Nucleic Acids Res 40: 5368-5377.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 5368-5377
-
-
Bultmann, S.1
Morbitzer, R.2
Schmidt, C.S.3
Thanisch, K.4
Spada, F.5
-
56
-
-
84875298381
-
A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly
-
Chen S, Oikonomou G, Chiu CN, Niles BJ, Liu J, et al. (2013) A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly. Nucleic Acids Res 41: 2769-2778.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 2769-2778
-
-
Chen, S.1
Oikonomou, G.2
Chiu, C.N.3
Niles, B.J.4
Liu, J.5
-
57
-
-
0037561538
-
Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation
-
DOI 10.1124/mol.64.1.160
-
Dvorak Z, Modriansky M, Pichard-Garcia L, Balaguer P, Vilarem MJ, et al. (2003) Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation. Mol Pharmacol 64: 160-169. (Pubitemid 36759828)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.1
, pp. 160-169
-
-
Dvorak, Z.1
Modriansky, M.2
Pichard-Garcia, L.3
Balaguer, P.4
Vilarem, M.-J.5
Ulrichova, J.6
Maurel, P.7
Pascussi, J.-M.8
-
58
-
-
84873733109
-
A TALEN genome-editing system for generating human stem cell-based disease models
-
Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, et al. (2013) A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell 12: 238-251.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 238-251
-
-
Ding, Q.1
Lee, Y.K.2
Schaefer, E.A.3
Peters, D.T.4
Veres, A.5
-
59
-
-
74949133880
-
Targeted chromosomal deletions in human cells using zinc finger nucleases
-
Lee HJ, Kim E, Kim JS (2010) Targeted chromosomal deletions in human cells using zinc finger nucleases. Genome Res 20: 81-89.
-
(2010)
Genome Res
, vol.20
, pp. 81-89
-
-
Lee, H.J.1
Kim, E.2
Kim, J.S.3
-
60
-
-
84884950106
-
CRISPR/Cas9 systems targeting beta-globin and CCR5 genes have substantial off-target activity
-
Cradick TJ, Fine EJ, Antico CJ, Bao G (2013) CRISPR/Cas9 systems targeting beta-globin and CCR5 genes have substantial off-target activity. Nucleic Acids Res 41: 9584-9592.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 9584-9592
-
-
Cradick, T.J.1
Fine, E.J.2
Antico, C.J.3
Bao, G.4
-
61
-
-
84891710947
-
Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
-
Cho SW, Kim S, Kim Y, Kweon J, Kim HS, et al. (2014) Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. Genome Res 24: 132-141.
-
(2014)
Genome Res
, vol.24
, pp. 132-141
-
-
Cho, S.W.1
Kim, S.2
Kim, Y.3
Kweon, J.4
Kim, H.S.5
-
63
-
-
80052766645
-
An unbiased genome-wide analysis of zinc-finger nuclease specificity
-
Gabriel R, Lombardo A, Arens A, Miller JC, Genovese P, et al. (2011) An unbiased genome-wide analysis of zinc-finger nuclease specificity. Nat Biotechnol 29: 816-823.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 816-823
-
-
Gabriel, R.1
Lombardo, A.2
Arens, A.3
Miller, J.C.4
Genovese, P.5
|