Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system

International Journal of Molecular Sciences

Volumn 14, Issue 10, 2013, Pages 19774-19781

  Horii, Takuro ^a   Tamura, Daiki ^a   Morita, Sumiyo ^a   Kimura, Mika ^a   Hatada, Izuho ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Cas9; CRISPR; DNMT3B; Genome engineering; ICF syndrome; iPS

Indexed keywords

DNA METHYLTRANSFERASE 3B; SATELLITE DNA;

ALLELE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CELL CULTURE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS SYSTEM; DNA METHYLATION; DNMT3B GENE; GENE MUTATION; GENE TARGETING; GENETIC ENGINEERING; GENETIC TRANSFECTION; GENOME; GENOTYPE; HUMAN; HUMAN CELL; IMMUNODEFICIENCY CENTROMERIC REGION INSTABILITY AND FACIAL ANOMALIES SYNDROME; MOLECULAR CLONING; PLURIPOTENT STEM CELL;

ALLELES; BASE SEQUENCE; CELL LINE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; GENE TARGETING; GENETIC ENGINEERING; GENOME; HUMANS; HYPERTELORISM; INDUCED PLURIPOTENT STEM CELLS; INTELLECTUAL DISABILITY; KYPHOSIS; MACROCEPHALY; MOLECULAR SEQUENCE DATA; RNA EDITING; TONGUE;

EID: 84885112722     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms141019774     Document Type: Article

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