A CRISPR/Cas9-based system for reprogramming cell lineage specification

Stem Cell Reports

Volumn 3, Issue 6, 2014, Pages 940-947

  Chakraborty, Syandan ^a,e   Ji, Hayeun ^a,e   Kabadi, Ami M ^a   Gersbach, Charles A ^a,b,c   Christoforou, Nicolas ^a,d   Leong, Kam W ^a,e  

^a Duke University   (United States)

^b DUKE UNIVERSITY   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d KHALIFA UNIVERSITY   (United Arab Emirates)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; MYOD1 PROTEIN; HYBRID PROTEIN; MYOD PROTEIN; MYOD1 MYOGENIC DIFFERENTIATION PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINEAGE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; EMBRYO; FIBROBLAST; GENE; GENE ACTIVATION; GENE DELIVERY SYSTEM; GENE LOCUS; GENE OVEREXPRESSION; MOUSE; MUSCLE CELL; MYOD1 GENE; NONHUMAN; NUCLEAR REPROGRAMMING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSACTIVATION; ANIMAL; ANTIBODY SPECIFICITY; CELL LINE; CRISPR CAS SYSTEM; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALS; CELL LINE; CELL LINEAGE; CELLULAR REPROGRAMMING; CRISPR-CAS SYSTEMS; GENE EXPRESSION; GENE EXPRESSION REGULATION; MICE; MYOD PROTEIN; ORGAN SPECIFICITY; RECOMBINANT FUSION PROTEINS;

EID: 84923798099     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2014.09.013     Document Type: Article

References (21)

1. D. Bikard, W. Jiang, P. Samai, A. Hochschild, F. Zhang, and L.A. Marraffini Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system Nucleic Acids Res. 41 2013 7429 7437
2. A.W. Cheng, H. Wang, H. Yang, L. Shi, Y. Katz, T.W. Theunissen, S. Rangarajan, C.S. Shivalila, D.B. Dadon, and R. Jaenisch Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system Cell Res. 23 2013 1163 1171
3. S.W. Cho, S. Kim, J.M. Kim, and J.S. Kim Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease Nat. Biotechnol. 31 2013 230 232
4. L. Cong, F.A. Ran, D. Cox, S. Lin, R. Barretto, N. Habib, P.D. Hsu, X. Wu, W. Jiang, L.A. Marraffini, and F. Zhang Multiplex genome engineering using CRISPR/Cas systems Science 339 2013 819 823
5. R.L. Davis, H. Weintraub, and A.B. Lassar Expression of a single transfected cDNA converts fibroblasts to myoblasts Cell 51 1987 987 1000
6. F. Farzadfard, S.D. Perli, and T.K. Lu Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas ACS Synth. Biol. 2 2013 604 613
7. X. Gao, J. Yang, J.C. Tsang, J. Ooi, D. Wu, and P. Liu Reprogramming to pluripotency using designer TALE transcription factors targeting enhancers Stem Cell Rev. 1 2013 183 197
8. L.A. Gilbert, M.H. Larson, L. Morsut, Z. Liu, G.A. Brar, S.E. Torres, N. Stern-Ginossar, O. Brandman, E.H. Whitehead, and J.A. Doudna CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes Cell 154 2013 442 451
9. W.Y. Hwang, Y. Fu, D. Reyon, M.L. Maeder, S.Q. Tsai, J.D. Sander, R.T. Peterson, J.R. Yeh, and J.K. Joung Efficient genome editing in zebrafish using a CRISPR-Cas system Nat. Biotechnol. 31 2013 227 229
10. M. Jinek, K. Chylinski, I. Fonfara, M. Hauer, J.A. Doudna, and E. Charpentier A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity Science 337 2012 816 821
11. M. Jinek, A. East, A. Cheng, S. Lin, E. Ma, and J. Doudna RNA-programmed genome editing in human cells eLife 2 2013 e00471
12. A.M. Kabadi, D.G. Ousterout, I.B. Hilton, and C.A. Gersbach Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector Nucleic Acids Res. 2014 10.1093/nar/gku749 Published online August 13, 2014
13. N.A. Kearns, R.M. Genga, M.S. Enuameh, M. Garber, S.A. Wolfe, and R. Maehr Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells Development 141 2014 219 223
14. S. Konermann, M.D. Brigham, A.E. Trevino, P.D. Hsu, M. Heidenreich, L. Cong, R.J. Platt, D.A. Scott, G.M. Church, and F. Zhang Optical control of mammalian endogenous transcription and epigenetic states Nature 500 2013 472 476
15. M.L. Maeder, S.J. Linder, V.M. Cascio, Y. Fu, Q.H. Ho, and J.K. Joung CRISPR RNA-guided activation of endogenous human genes Nat. Methods 10 2013 977 979
16. P. Mali, J. Aach, P.B. Stranges, K.M. Esvelt, M. Moosburner, S. Kosuri, L. Yang, and G.M. Church CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering Nat. Biotechnol. 31 2013 833 838
17. P. Mali, L. Yang, K.M. Esvelt, J. Aach, M. Guell, J.E. DiCarlo, J.E. Norville, and G.M. Church RNA-guided human genome engineering via Cas9 Science 339 2013 823 826
18. P. Perez-Pinera, D.D. Kocak, C.M. Vockley, A.F. Adler, A.M. Kabadi, L.R. Polstein, P.I. Thakore, K.A. Glass, D.G. Ousterout, and K.W. Leong RNA-guided gene activation by CRISPR-Cas9-based transcription factors Nat. Methods 10 2013 973 976
19. L.S. Qi, M.H. Larson, L.A. Gilbert, J.A. Doudna, J.S. Weissman, A.P. Arkin, and W.A. Lim Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression Cell 152 2013 1173 1183
20. K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676
21. J.M. Zingg, G. Pedraza-Alva, and J.P. Jost MyoD1 promoter autoregulation is mediated by two proximal E-boxes Nucleic Acids Res. 22 1994 2234 2241