Progress in the development of fatty acid synthase inhibitors as anticancer targets

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 20, 2015, Pages 4363-4369

  Mullen, Genevieve E ^a   Yet, Larry ^a  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

Anticancer; Fatty acid synthase; Inhibitors; Natural products

Indexed keywords

3,3' DIINDOLYLMETHANE; AMENTOFLAVONE; ANTINEOPLASTIC AGENT; CERULENIN; EPIGALLOCATECHIN GALLATE; FATTY ACID SYNTHASE INHIBITOR; LUTEOLIN; MOLLUGIN; ORIDONIN; OSTHOLE; QUERCETIN; RESVERATROL; TETRAHYDROLIPSTATIN; UNCLASSIFIED DRUG; FATTY ACID SYNTHASE;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER THERAPY; CARCINOMA; CRYSTAL STRUCTURE; DRUG BIOAVAILABILITY; DRUG RESEARCH; DRUG SOLUBILITY; ENZYME SPECIFICITY; FATTY ACID SYNTHESIS; HUMAN; IC50; NONHUMAN; X RAY CRYSTALLOGRAPHY; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; METABOLISM; NEOPLASMS; PATHOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; FATTY ACID SYNTHASE, TYPE I; FATTY ACID SYNTHESIS INHIBITORS; HUMANS; NEOPLASMS;

EID: 84942817046     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.08.087     Document Type: Review

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