Fatty acid synthase inhibition by amentoflavone induces apoptosis and antiproliferation in human breast cancer cells

Biological and Pharmaceutical Bulletin

Volumn 32, Issue 8, 2009, Pages 1427-1432

  Lee, Jin Sun ^a   Lee, Myung Sun ^b   Oh, Won Keun ^c   Sul, Ji Young ^a,b  

^a Chungnam National University College of Medicine   (South Korea)

^b Chungnam National University   (South Korea)

^c Chosun University   (South Korea)

Author keywords

Amentoflavone; Apoptosis; Breast cancer; Fatty acid synthesis

Indexed keywords

ACETYL COENZYME A; AMENTOFLAVONE; CASPASE 3; CASPASE INHIBITOR; FATTY ACID SYNTHASE; LIPID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL GROWTH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; FATTY ACID SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SELAGINELLA; SELAGINELLA TAMARISCINA;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BIFLAVONOIDS; BLOTTING, WESTERN; BREAST NEOPLASMS; CASPASE 3; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACID SYNTHETASE COMPLEX; FEMALE; HUMANS; MICE; NIH 3T3 CELLS; POLY ADENOSINE DIPHOSPHATE RIBOSE; SELAGINELLACEAE; TIME FACTORS;

EID: 69149106050     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.32.1427     Document Type: Article

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