In vitro inhibition of fatty acid synthase by 1,2,3,4,6-penta-O-galloyl- β-d-glucose plays a vital role in anti-tumour activity

Biochemical and Biophysical Research Communications

Volumn 445, Issue 2, 2014, Pages 346-351

  Zhao, Wenhua ^a   Wang, Yuji ^a   Hao, Weijia ^a   Zhao, Ming ^a   Peng, Shiqi ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

1,2,3,4,6 Penta O galloyl d glucose (PGG); Anti tumour; Fatty acid synthase (FAS)

Indexed keywords

1,2,3,4,6 PENTA O GALLOYL BETA DEXTRO GLUCOSE; ANTINEOPLASTIC AGENT; CASPASE 3; EPICATECHIN GALLATE; FAS ANTIGEN; FATTY ACID SYNTHASE; MORIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISSOCIATION CONSTANT; DOWN REGULATION; DRUG BINDING; ENZYME ACTIVATION; ENZYME INHIBITION; GLIOMA CELL; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; KINETICS; PRECIPITATION; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE;

1,2,3,4,6-PENTA-O-GALLOYL-Β-D-GLUCOSE (PGG); ANTI-TUMOUR; FATTY ACID SYNTHASE (FAS);

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; ENZYME ACTIVATION; ENZYME INHIBITORS; FATTY ACID SYNTHASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYDROLYZABLE TANNINS; NEOPLASMS;

EID: 84896082119     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.01.191     Document Type: Article

References (28)

1. T. Maier, M. Leibundgut, and N. Ban The crystal structure of a mammalian fatty acid synthase Science 321 2008 1315 1322
2. L.Z. Milgraum, L.A. Witters, G.R. Pasternack, and F.P. Kuhajda Enzymes of the fatty acid synthesis pathway are highly expressed in situ breast carcinoma Clin. Cancer Res. 3 1997 2115 2120 (Pubitemid 27505140)
3. F.P. Kuhajda Fatty acid synthase and cancer: new application of an old pathway Cancer Res. 66 2006 5977 5980
4. R. Flavin, S. Peluso, P.L. Nguyen, and M. Loda Fatty acid synthase as a potential therapeutic target in cancer Future Oncol. 6 2010 551 562
5. J.V. Swinnen, T. Roskams, S. Joniau, H. Van Poppel, R. Oyen, L. Baert, W. Heyns, and G. Verhoeven Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer Int. J. Cancer 98 2002 19 22 (Pubitemid 34113412)
6. P. Visca, V. Sebastiani, C. Botti, M.G. Diodoro, R.P. Lasagni, F. Romagnoli, A. Brenna, B.C. De Joannon, R.P. Donnorso, G. Lombardi, and P.L. Alo Fatty acid synthase (FAS) is a marker of increased risk of recurrence in lung carcinoma Anticancer Res. 24 2004 4169 4173 (Pubitemid 40468723)
7. T. Migita, S. Ruiz, A. Fornari, M. Fiorentino, C. Priolo, G. Zadra, F. Inazuka, C. Grisanzio, E. Palescandolo, E. Shin, C. Fiore, W. Xie, A.L. Kung, P.G. Febbo, A. Subramanian, L. Mucci, J. Ma, S. Signoretti, M. Stampfer, W.C. Hahn, S. Finn, and M. Loda Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer J. Natl. Cancer Inst. 101 2009 519 532
8. W.X. Tian Fatty acid synthase by polyphenols Curr. Med. Chem. 13 2006 967 997
9. T.M. Loftus, D.E. Jaworsky, G.L. Frehywot, C.A. Townsend, G.V. Ronnett, M.D. Lane, and F.P. Kuhajda Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors Science 288 2000 2379 2381 (Pubitemid 30448165)
10. R. Zhang, W.P. Xiao, X. Wang, X.D. Wu, and W.X. Tian Novel inhibitors of fatty-acid synthase from green tea (Camellia sinensis Xihu Longjing) with high activity and a new reacting site Biotechnol. Appl. Biochem. 43 2006 1 7 (Pubitemid 43059033)
11. S.Y. Zhang, C.G. Zheng, X.Y. Yan, and W.X. Tian Low concentration of condensed tannins from catechu significantly inhibits fatty acid synthase and growth of MCF-7 cellsm Biochem. Biophs. Res. Commun. 371 2008 654 658
12. X.B. Sun, and W.X. Tian Inhibitory effects of allium vegetable extracts on fatty acid synthase Food Sci. Technol. Res. 15 2009 343 346
13. W.H. Zhao, J.F. Zhang, Z. Wang, Y.X. Zhang, and W.X. Tian The extract of leaves of Acer truncatum Bunge: a natural inhibitor of fatty acid synthase with antitumor activity J. Enzyme Inhib. Med. Chem. 21 2006 589 596
14. W.H. Zhao, Ch.Ch. Gao, Y.X. Zhang, and W.X. Tian Evaluation of the inhibitory activities of aceraceous plants on fatty acid synthase J. Enzyme Inhib. Med. Chem. 22 2007 501 510
15. W.H. Zhao, Ch.Ch. Gao, X.F. Ma, X.Y. Bai, and Y.X. Zhang The isolation of 1,2,3,4,6-penta-O-galloyl-beta-d-glucose from Acer truncatum Bunge by high-speed counter-current chromatography J. Chromatogr. B 850 2007 523 527
16. W.H. Zhao, L.F. Gao, W. Gao, Y. Sh. Yuan, Ch.Ch. Gao, L.G. Cao, Z.Z. Hu, J.X. Guo, and Y.X. Zhang Weight reducing effect of Acer truncatum Bunge may be related to the inhibition of fatty acid synthase Nat. Prod. Res. 25 2011 422 431
17. J.Y. Cho, M.J. Sohn, J.K. Lee, and W.G. Kim Isolation and identification of pentagalloylglucose with broad-spectrum antibacterial activity from Rhus trichocarpa Miquel Food Chem. 123 2010 501 506
18. Y. Pei, Z.P. Chen, H.Q. Ju, M. Komatsu, Y. Ji, G. Liu, C.W. Guo, Y.J. Zhang, C.R. Yang, Y.F. Wang, and K. Kitazato Autophagy is involved in anti-viral activity of pentagalloylglucose (PGG) against Herpes simplex virus type 1 infection in vitro Biochem. Biophs. Res. Commun. 405 2011 186 191
19. J. Lee, D.S. Jang, N.H. Kim, Y.M. Lee, J.H. Kim, and J.S. Kim Galloyl glucoses from the seeds of Cornus officinalis with inhibitory activity against protein glycation, aldose reductase, and cataractogenesis ex vivo Biol. Pharm. Bull. 34 2011 443 446
20. εRI expression in vitro and in vivo FEBS Lett. 584 2010 111 118
21. J.H. Zhang, L. Li, S.H. Kim, A.E. Hagerman, and J.X. Lü Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose Pharm. Res. 26 2009 2066 2079
22. H.B. Hu, Y.B. Chai, L. Wang, J.H. Zhang, H.J. Lee, S.H. Kim, and J.X. Lu Pentagalloylglucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells Mol. Cancer Ther. 8 2009 2833 2843
23. H.J. Lee, N.J. Seo, S.J. Jeong, Y.J. Park, D.B. Jung, W.H. Koh, H.J. Lee, E.O. Lee, K.S. Ahn, K.S. Ahn, J. Lü, and S.H. Kim Oral administration of penta-O-galloyl-β-d-glucose suppresses triple-negative breast cancer xenograft growth and metastasis in strong association with JAK1-STAT3 Inhibition Carcinogenesis 32 2011 804 811
24. L. Li, A.A. Shaika, J.H. Zhang, K. Nhkata, L. Wang, Y. Zhang, C.G. Xing, S.H. Kim, and J.X. Lü Preparation of penta-O-galloyl-beta-d-glucose from tannic acid and plasma pharmacokinetic analyses by liquid-liquid extraction and reverse-phase HPLC J. Pharm. Biomed. Anal. 54 2011 545 550
25. J.E. Huh, E.O. Lee, M.S. Kim, K.S. Kang, C.H. Kim, B.C. Cha, Y.J. Surh, and S.H. Kim Penta-O-galloyl-beta-d-glucose suppresses tumor growth via inhibition of angiogenesis and stimulation of apoptosis: roles of cyclooxygenase-2 and mitogen-activated protein kinase pathways Carcinogenesis 26 2005 1436 1445
26. M. Yoshiyuki, J.H.i. Zhang, A. Pugliese, S.H. Kim, and J. Lu Anti-cancer gallotannin pentaglucose is a nanomolar inhibitor of select mammalian DNA polymerases Biochem. Pharmacol. 80 2010 1125 1132
27. K. Cai, A.E. Hagerman, R.E. Minto, and A. Bennick Decreased polyphenol transport across cultured intestinal cells by a salivary proline-rich protein Biochem. Pharmacol. 71 2006 1570 1580
28. X. Wang, K.S. Song, Q.X. Guo, and W.X. Tian The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase Biochem. Pharmacol. 66 2003 2039 2047 (Pubitemid 37352867)