Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-β1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling

Journal of Agricultural and Food Chemistry

Volumn 55, Issue 13, 2007, Pages 5030-5037

  Pan, Min Hsiung ^a   Lin, Cheng Chan ^b   Lin, Jen Kun ^c   Chen, Wei Jen ^b  

^a NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

( ) Epigallocatechin 3 gallate (EGCG); Akt; Extracellular signal regulated kinase1 2 (ERK1 2); Fatty acid synthase (FAS); HER2; HER3; Heregulin 1

Indexed keywords

CATECHIN; DRUG DERIVATIVE; EPIGALLOCATECHIN GALLATE; FATTY ACID SYNTHASE; HEREGULIN BETA1; MITOGEN ACTIVATED PROTEIN KINASE; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ARTICLE; BREAST TUMOR; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; SIGNAL TRANSDUCTION; TEA; TUMOR CELL LINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BREAST NEOPLASMS; CATECHIN; CELL LINE, TUMOR; FATTY ACID SYNTHETASE COMPLEX; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; NEUREGULIN-1; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TEA;

EID: 34447295657     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf070316r     Document Type: Article

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