Fatty acid synthase plays a role in cancer metabolism beyond providing fatty acids for phospholipid synthesis or sustaining elevations in glycolytic activity

Experimental Cell Research

Volumn 320, Issue 2, 2014, Pages 302-310

  Hopperton, Kathryn E ^a   Duncan, Robin E ^a,b   Bazinet, Richard P ^a   Archer, Michael C ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF WATERLOO   (Canada)

Author keywords

Cancer cells; Fatty acid excretion; Fatty acid synthesis; Fatty acid utilization; Glycolysis

Indexed keywords

ACETIC ACID DERIVATIVE; CARBON 14 ACETATE; CARBON 14 PALMITATE; FATTY ACID; FATTY ACID SYNTHASE; LIPID; PALMITIC ACID; PHOSPHOLIPID; UNCLASSIFIED DRUG;

ANOXIA; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER METABOLISM; COMPARATIVE STUDY; CULTURE MEDIUM; EPITHELIUM CELL; FATTY ACID SYNTHESIS; GLYCOLYSIS; HUMAN; HUMAN CELL; LIPOGENESIS; LIQUID SCINTILLATION COUNTING; METABOLISM; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; RADIOACTIVITY; THIN LAYER CHROMATOGRAPHY;

CANCER CELLS; CE; CERAMIDE-1-PHOSPHOCHOLINE; CERPCHO; CHOGPL; CHOLESTERYL ESTERS; CHOLINE GLYCEROPHOSPHOLIPID; DAG; DIACYLGLYCERIDES; ETHANOLAMINE GLYCEROPHOSPHOLIPID; ETHGPL; FASN; FATTY ACID EXCRETION; FATTY ACID SYNTHASE; FATTY ACID SYNTHESIS; FATTY ACID UTILIZATION; FFA; FREE FATTY ACIDS; GLYCOLYSIS; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLSERINE; PHOSPHOLIPIDS; PL; PTDINS; PTDSER; TAG; THIN LAYER CHROMATOGRAPHY; TLC; TRIACYLGLYCERIDES;

CELL HYPOXIA; CELLS, CULTURED; ESTERIFICATION; FATTY ACID SYNTHASE, TYPE I; FATTY ACIDS; FEMALE; GLYCOLYSIS; HUMANS; LIPID METABOLISM; LIPOGENESIS; MCF-7 CELLS; NEOPLASMS; PHOSPHOLIPIDS;

EID: 84890859981     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.10.016     Document Type: Article

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