메뉴 건너뛰기




Volumn 12, Issue , 2012, Pages

Different fatty acid metabolism effects of (-)-Epigallocatechin-3-Gallate and C75 in Adenocarcinoma lung cancer

Author keywords

C75; EGCG; EGFR; Fatty acid metabolism; Fatty acid synthase; Inhibitors; Lung cancer; Weight loss; Xenograft

Indexed keywords

CPT ENZYME; ENZYME; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIGALLOCATECHIN GALLATE; FATTY ACID; FATTY ACID SYNTHASE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 84863443673     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-12-280     Document Type: Article
Times cited : (85)

References (44)
  • 1
    • 0028557012 scopus 로고
    • The animal fatty acid synthase: one gene, one polypeptide, seven enzymes
    • Smith S. The animal fatty acid synthase: one gene, one polypeptide, seven enzymes. FASEB J 1994, 8(15):1248-1259.
    • (1994) FASEB J , vol.8 , Issue.15 , pp. 1248-1259
    • Smith, S.1
  • 2
    • 0034002793 scopus 로고    scopus 로고
    • Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology
    • 10.1016/S0899-9007(99)00266-X, 10705076
    • Kuhajda FP. Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology. Nutrition 2000, 16(3):202-208. 10.1016/S0899-9007(99)00266-X, 10705076.
    • (2000) Nutrition , vol.16 , Issue.3 , pp. 202-208
    • Kuhajda, F.P.1
  • 3
    • 33745728461 scopus 로고    scopus 로고
    • Fatty acid synthase and cancer: new application of an old pathway
    • 10.1158/0008-5472.CAN-05-4673, 16778164
    • Kuhajda FP. Fatty acid synthase and cancer: new application of an old pathway. Cancer Res 2006, 66(12):5977-5980. 10.1158/0008-5472.CAN-05-4673, 16778164.
    • (2006) Cancer Res , vol.66 , Issue.12 , pp. 5977-5980
    • Kuhajda, F.P.1
  • 4
    • 34748912615 scopus 로고    scopus 로고
    • Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
    • 10.1038/nrc2222, 17882277
    • Menendez JA, Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer 2007, 7(10):763-777. 10.1038/nrc2222, 17882277.
    • (2007) Nat Rev Cancer , vol.7 , Issue.10 , pp. 763-777
    • Menendez, J.A.1    Lupu, R.2
  • 5
    • 0030706079 scopus 로고    scopus 로고
    • Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma
    • Milgraum LZ, Witters LA, Pasternack GR, Kuhajda FP. Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma. Clin Cancer Res 1997, 3(11):2115-2120.
    • (1997) Clin Cancer Res , vol.3 , Issue.11 , pp. 2115-2120
    • Milgraum, L.Z.1    Witters, L.A.2    Pasternack, G.R.3    Kuhajda, F.P.4
  • 6
    • 0036497907 scopus 로고    scopus 로고
    • Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer
    • 10.1002/ijc.10127, 11857379
    • Swinnen JV, Roskams T, Joniau S, Van Poppel H, Oyen R, Baert L, Heyns W, Verhoeven G. Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer. Int J Cancer 2002, 98(1):19-22. 10.1002/ijc.10127, 11857379.
    • (2002) Int J Cancer , vol.98 , Issue.1 , pp. 19-22
    • Swinnen, J.V.1    Roskams, T.2    Joniau, S.3    Van Poppel, H.4    Oyen, R.5    Baert, L.6    Heyns, W.7    Verhoeven, G.8
  • 7
    • 0033808261 scopus 로고    scopus 로고
    • The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung
    • 10.1053/hupa.2000.9842, 11014573
    • Piyathilake CJ, Frost AR, Manne U, Bell WC, Weiss H, Heimburger DC, Grizzle WE. The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung. Hum Pathol 2000, 31(9):1068-1073. 10.1053/hupa.2000.9842, 11014573.
    • (2000) Hum Pathol , vol.31 , Issue.9 , pp. 1068-1073
    • Piyathilake, C.J.1    Frost, A.R.2    Manne, U.3    Bell, W.C.4    Weiss, H.5    Heimburger, D.C.6    Grizzle, W.E.7
  • 8
    • 84869150440 scopus 로고    scopus 로고
    • Design of Anti-Fasn Molecules as a New Anti-Tumour Modality
    • Publishers BS
    • Relat J, Puig T. Design of Anti-Fasn Molecules as a New Anti-Tumour Modality. Frontiers in Drug Design & Discovery 2010, Publishers BS.
    • (2010) Frontiers in Drug Design & Discovery
    • Relat, J.1    Puig, T.2
  • 12
    • 0036469122 scopus 로고    scopus 로고
    • Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells
    • Van de Sande T, De Schrijver E, Heyns W, Verhoeven G, Swinnen JV. Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells. Cancer Res 2002, 62(3):642-646.
    • (2002) Cancer Res , vol.62 , Issue.3 , pp. 642-646
    • Van de Sande, T.1    De Schrijver, E.2    Heyns, W.3    Verhoeven, G.4    Swinnen, J.V.5
  • 13
    • 3142720785 scopus 로고    scopus 로고
    • Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB
    • Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB. Int J Oncol 2004, 24(3):591-608.
    • (2004) Int J Oncol , vol.24 , Issue.3 , pp. 591-608
    • Menendez, J.A.1    Mehmi, I.2    Atlas, E.3    Colomer, R.4    Lupu, R.5
  • 14
    • 34548814981 scopus 로고    scopus 로고
    • Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells
    • 10.1074/jbc.M702854200, 17631500
    • Yoon S, Lee MY, Park SW, Moon JS, Koh YK, Ahn YH, Park BW, Kim KS. Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells. J Biol Chem 2007, 282(36):26122-26131. 10.1074/jbc.M702854200, 17631500.
    • (2007) J Biol Chem , vol.282 , Issue.36 , pp. 26122-26131
    • Yoon, S.1    Lee, M.Y.2    Park, S.W.3    Moon, J.S.4    Koh, Y.K.5    Ahn, Y.H.6    Park, B.W.7    Kim, K.S.8
  • 15
    • 38549147538 scopus 로고    scopus 로고
    • Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells
    • 10.1111/j.1365-2184.2007.00498.x, 18211286
    • Vazquez-Martin A, Colomer R, Brunet J, Lupu R, Menendez JA. Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells. Cell Prolif 2008, 41(1):59-85. 10.1111/j.1365-2184.2007.00498.x, 18211286.
    • (2008) Cell Prolif , vol.41 , Issue.1 , pp. 59-85
    • Vazquez-Martin, A.1    Colomer, R.2    Brunet, J.3    Lupu, R.4    Menendez, J.A.5
  • 17
    • 33750619348 scopus 로고    scopus 로고
    • Glucose metabolism and cancer
    • 10.1016/j.ceb.2006.10.005, 17046224
    • Shaw RJ. Glucose metabolism and cancer. Curr Opin Cell Biol 2006, 18(6):598-608. 10.1016/j.ceb.2006.10.005, 17046224.
    • (2006) Curr Opin Cell Biol , vol.18 , Issue.6 , pp. 598-608
    • Shaw, R.J.1
  • 18
    • 77950881796 scopus 로고    scopus 로고
    • The SDF-1alpha/CXCR4 axis induces the expression of fatty acid synthase via sterol regulatory element-binding protein-1 activation in cancer cells
    • 10.1093/carcin/bgp329, 20067991
    • Kim K, Kim HY, Cho HK, Kim KH, Cheong J. The SDF-1alpha/CXCR4 axis induces the expression of fatty acid synthase via sterol regulatory element-binding protein-1 activation in cancer cells. Carcinogenesis 2010, 31(4):679-686. 10.1093/carcin/bgp329, 20067991.
    • (2010) Carcinogenesis , vol.31 , Issue.4 , pp. 679-686
    • Kim, K.1    Kim, H.Y.2    Cho, H.K.3    Kim, K.H.4    Cheong, J.5
  • 19
    • 0015496929 scopus 로고
    • Inhibition of fatty acid synthetases by the antibiotic cerulenin
    • 10.1016/0006-291X(72)90397-X, 4625866
    • Vance D, Goldberg I, Mitsuhashi O, Bloch K. Inhibition of fatty acid synthetases by the antibiotic cerulenin. Biochem Biophys Res Commun 1972, 48(3):649-656. 10.1016/0006-291X(72)90397-X, 4625866.
    • (1972) Biochem Biophys Res Commun , vol.48 , Issue.3 , pp. 649-656
    • Vance, D.1    Goldberg, I.2    Mitsuhashi, O.3    Bloch, K.4
  • 20
    • 33749329775 scopus 로고    scopus 로고
    • Fatty acid synthase: a novel target for antiglioma therapy
    • 10.1038/sj.bjc.6603350, 2360524, 16969344
    • Zhao W, Kridel S, Thorburn A, Kooshki M, Little J, Hebbar S, Robbins M. Fatty acid synthase: a novel target for antiglioma therapy. Br J Cancer 2006, 95(7):869-878. 10.1038/sj.bjc.6603350, 2360524, 16969344.
    • (2006) Br J Cancer , vol.95 , Issue.7 , pp. 869-878
    • Zhao, W.1    Kridel, S.2    Thorburn, A.3    Kooshki, M.4    Little, J.5    Hebbar, S.6    Robbins, M.7
  • 21
    • 0034724397 scopus 로고    scopus 로고
    • Synthesis and antitumor activity of an inhibitor of fatty acid synthase
    • 10.1073/pnas.97.7.3450, 16260, 10716717
    • Kuhajda FP, Pizer ES, Li JN, Mani NS, Frehywot GL, Townsend CA. Synthesis and antitumor activity of an inhibitor of fatty acid synthase. Proc Natl Acad Sci U S A 2000, 97(7):3450-3454. 10.1073/pnas.97.7.3450, 16260, 10716717.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.7 , pp. 3450-3454
    • Kuhajda, F.P.1    Pizer, E.S.2    Li, J.N.3    Mani, N.S.4    Frehywot, G.L.5    Townsend, C.A.6
  • 22
  • 23
    • 0035900577 scopus 로고    scopus 로고
    • Green tea epigallocatechin gallate: a natural inhibitor of fatty-acid synthase
    • 10.1006/bbrc.2001.5923, 11700039
    • Wang X, Tian W. Green tea epigallocatechin gallate: a natural inhibitor of fatty-acid synthase. Biochem Biophys Res Commun 2001, 288(5):1200-1206. 10.1006/bbrc.2001.5923, 11700039.
    • (2001) Biochem Biophys Res Commun , vol.288 , Issue.5 , pp. 1200-1206
    • Wang, X.1    Tian, W.2
  • 24
    • 0041337028 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells
    • 10.1002/ijc.11317, 12918062
    • Brusselmans K, De Schrijver E, Heyns W, Verhoeven G, Swinnen JV. Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells. Int J Cancer 2003, 106(6):856-862. 10.1002/ijc.11317, 12918062.
    • (2003) Int J Cancer , vol.106 , Issue.6 , pp. 856-862
    • Brusselmans, K.1    De Schrijver, E.2    Heyns, W.3    Verhoeven, G.4    Swinnen, J.V.5
  • 26
    • 58149176097 scopus 로고    scopus 로고
    • Green tea catechin inhibits fatty acid synthase without stimulating carnitine palmitoyltransferase-1 or inducing weight loss in experimental animals
    • Puig T, Relat J, Marrero PF, Haro D, Brunet J, Colomer R. Green tea catechin inhibits fatty acid synthase without stimulating carnitine palmitoyltransferase-1 or inducing weight loss in experimental animals. Anticancer Res 2008, 28(6A):3671-3676.
    • (2008) Anticancer Res , vol.28 , Issue.6 A , pp. 3671-3676
    • Puig, T.1    Relat, J.2    Marrero, P.F.3    Haro, D.4    Brunet, J.5    Colomer, R.6
  • 28
    • 34249056553 scopus 로고    scopus 로고
    • FDG-PET for pharmacodynamic assessment of the fatty acid synthase inhibitor C75 in an experimental model of lung cancer
    • 10.1007/s11095-007-9264-x, 17404812
    • Lee JS, Orita H, Gabrielson K, Alvey S, Hagemann RL, Kuhajda FP, Gabrielson E, Pomper MG. FDG-PET for pharmacodynamic assessment of the fatty acid synthase inhibitor C75 in an experimental model of lung cancer. Pharm Res 2007, 24(6):1202-1207. 10.1007/s11095-007-9264-x, 17404812.
    • (2007) Pharm Res , vol.24 , Issue.6 , pp. 1202-1207
    • Lee, J.S.1    Orita, H.2    Gabrielson, K.3    Alvey, S.4    Hagemann, R.L.5    Kuhajda, F.P.6    Gabrielson, E.7    Pomper, M.G.8
  • 29
    • 77952073947 scopus 로고    scopus 로고
    • Epigallocatechin gallate suppresses lung cancer cell growth through Ras-GTPase-activating protein SH3 domain-binding protein 1
    • Shim JH, Su ZY, Chae JI, Kim DJ, Zhu F, Ma WY, Bode AM, Yang CS, Dong Z. Epigallocatechin gallate suppresses lung cancer cell growth through Ras-GTPase-activating protein SH3 domain-binding protein 1. Canc Prev Res Phila 2010, 3(5):670-679.
    • (2010) Canc Prev Res Phila , vol.3 , Issue.5 , pp. 670-679
    • Shim, J.H.1    Su, Z.Y.2    Chae, J.I.3    Kim, D.J.4    Zhu, F.5    Ma, W.Y.6    Bode, A.M.7    Yang, C.S.8    Dong, Z.9
  • 30
    • 77952305329 scopus 로고    scopus 로고
    • Pro-oxidative activities and dose-response relationship of (-)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro
    • 10.1093/carcin/bgq039, 2864413, 20159951
    • Li GX, Chen YK, Hou Z, Xiao H, Jin H, Lu G, Lee MJ, Liu B, Guan F, Yang Z, et al. Pro-oxidative activities and dose-response relationship of (-)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro. Carcinogenesis 2010, 31(5):902-910. 10.1093/carcin/bgq039, 2864413, 20159951.
    • (2010) Carcinogenesis , vol.31 , Issue.5 , pp. 902-910
    • Li, G.X.1    Chen, Y.K.2    Hou, Z.3    Xiao, H.4    Jin, H.5    Lu, G.6    Lee, M.J.7    Liu, B.8    Guan, F.9    Yang, Z.10
  • 31
    • 67649340851 scopus 로고    scopus 로고
    • Identification of epigallocatechin-3-gallate in green tea polyphenols as a potent inducer of p53-dependent apoptosis in the human lung cancer cell line A549
    • Yamauchi R, Sasaki K, Yoshida K. Identification of epigallocatechin-3-gallate in green tea polyphenols as a potent inducer of p53-dependent apoptosis in the human lung cancer cell line A549. Toxicol Vitro 2009, 23(5):834-839.
    • (2009) Toxicol Vitro , vol.23 , Issue.5 , pp. 834-839
    • Yamauchi, R.1    Sasaki, K.2    Yoshida, K.3
  • 32
    • 0037226462 scopus 로고    scopus 로고
    • Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis
    • Kumar-Sinha C, Ignatoski KW, Lippman ME, Ethier SP, Chinnaiyan AM. Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis. Cancer Res 2003, 63(1):132-139.
    • (2003) Cancer Res , vol.63 , Issue.1 , pp. 132-139
    • Kumar-Sinha, C.1    Ignatoski, K.W.2    Lippman, M.E.3    Ethier, S.P.4    Chinnaiyan, A.M.5
  • 33
    • 12344278357 scopus 로고    scopus 로고
    • Fatty acid synthase-catalyzed de novo fatty acid biosynthesis: from anabolic-energy-storage pathway in normal tissues to jack-of-all-trades in cancer cells
    • Menendez JA, Lupu R. Fatty acid synthase-catalyzed de novo fatty acid biosynthesis: from anabolic-energy-storage pathway in normal tissues to jack-of-all-trades in cancer cells. Arch Immunol Ther Exp (Warsz) 2004, 52(6):414-426.
    • (2004) Arch Immunol Ther Exp (Warsz) , vol.52 , Issue.6 , pp. 414-426
    • Menendez, J.A.1    Lupu, R.2
  • 34
    • 30444434391 scopus 로고    scopus 로고
    • Targeting fatty acid synthase: potential for therapeutic intervention in her-2/neu-overexpressing breast cancer
    • 10.1358/dnp.2005.18.6.927929, 16247515
    • Menendez JA, Lupu R, Colomer R. Targeting fatty acid synthase: potential for therapeutic intervention in her-2/neu-overexpressing breast cancer. Drug News Perspect 2005, 18(6):375-385. 10.1358/dnp.2005.18.6.927929, 16247515.
    • (2005) Drug News Perspect , vol.18 , Issue.6 , pp. 375-385
    • Menendez, J.A.1    Lupu, R.2    Colomer, R.3
  • 36
    • 0030930265 scopus 로고    scopus 로고
    • Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells
    • 10.1002/(SICI)1097-4644(19971001)67:1<55::AID-JCB6>3.0.CO;2-V, 9328839
    • Liang YC, Lin-shiau SY, Chen CF, Lin JK. Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells. J Cell Biochem 1997, 67(1):55-65. 10.1002/(SICI)1097-4644(19971001)67:1<55::AID-JCB6>3.0.CO;2-V, 9328839.
    • (1997) J Cell Biochem , vol.67 , Issue.1 , pp. 55-65
    • Liang, Y.C.1    Lin-shiau, S.Y.2    Chen, C.F.3    Lin, J.K.4
  • 37
    • 22744459749 scopus 로고    scopus 로고
    • EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells
    • Shimizu M, Deguchi A, Joe AK, Mckoy JF, Moriwaki H, Weinstein IB. EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells. J Exp Ther Oncol 2005, 5(1):69-78.
    • (2005) J Exp Ther Oncol , vol.5 , Issue.1 , pp. 69-78
    • Shimizu, M.1    Deguchi, A.2    Joe, A.K.3    Mckoy, J.F.4    Moriwaki, H.5    Weinstein, I.B.6
  • 38
    • 17644401337 scopus 로고    scopus 로고
    • (-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells
    • 10.1158/1078-0432.CCR-04-2014, 15814656
    • Shimizu M, Deguchi A, Lim JT, Moriwaki H, Kopelovich L, Weinstein IB. (-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells. Clin Cancer Res 2005, 11(7):2735-2746. 10.1158/1078-0432.CCR-04-2014, 15814656.
    • (2005) Clin Cancer Res , vol.11 , Issue.7 , pp. 2735-2746
    • Shimizu, M.1    Deguchi, A.2    Lim, J.T.3    Moriwaki, H.4    Kopelovich, L.5    Weinstein, I.B.6
  • 39
    • 0036801990 scopus 로고    scopus 로고
    • Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability
    • Lee MJ, Maliakal P, Chen L, Meng X, Bondoc FY, Prabhu S, Lambert G, Mohr S, Yang CS. Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability. Canc Epidemiol Biomarkers Prev 2002, 11(10 Pt 1):1025-1032.
    • (2002) Canc Epidemiol Biomarkers Prev , vol.11 , Issue.10 PART 1 , pp. 1025-1032
    • Lee, M.J.1    Maliakal, P.2    Chen, L.3    Meng, X.4    Bondoc, F.Y.5    Prabhu, S.6    Lambert, G.7    Mohr, S.8    Yang, C.S.9
  • 40
    • 31444434449 scopus 로고    scopus 로고
    • MTOR signaling: implications for cancer and anticancer therapy
    • 10.1038/sj.bjc.6602902, 2361102, 16404421
    • Petroulakis E, Mamane Y, Le Bacquer O, Shahbazian D, Sonenberg N. mTOR signaling: implications for cancer and anticancer therapy. Br J Cancer 2006, 94(2):195-199. 10.1038/sj.bjc.6602902, 2361102, 16404421.
    • (2006) Br J Cancer , vol.94 , Issue.2 , pp. 195-199
    • Petroulakis, E.1    Mamane, Y.2    Le Bacquer, O.3    Shahbazian, D.4    Sonenberg, N.5
  • 41
    • 77951279924 scopus 로고    scopus 로고
    • Osthole suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt/mTOR pathway
    • 10.1021/jf100352c, 20218616
    • Lin VC, Chou CH, Lin YC, Lin JN, Yu CC, Tang CH, Lin HY, Way TD. Osthole suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt/mTOR pathway. J Agric Food Chem 2010, 58(8):4786-4793. 10.1021/jf100352c, 20218616.
    • (2010) J Agric Food Chem , vol.58 , Issue.8 , pp. 4786-4793
    • Lin, V.C.1    Chou, C.H.2    Lin, Y.C.3    Lin, J.N.4    Yu, C.C.5    Tang, C.H.6    Lin, H.Y.7    Way, T.D.8
  • 42
    • 70349649506 scopus 로고    scopus 로고
    • EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells
    • 10.1002/mnfr.200800592, 19662644
    • Huang CH, Tsai SJ, Wang YJ, Pan MH, Kao JY, Way TD. EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells. Mol Nutr Food Res 2009, 53(9):1156-1165. 10.1002/mnfr.200800592, 19662644.
    • (2009) Mol Nutr Food Res , vol.53 , Issue.9 , pp. 1156-1165
    • Huang, C.H.1    Tsai, S.J.2    Wang, Y.J.3    Pan, M.H.4    Kao, J.Y.5    Way, T.D.6
  • 43
    • 0033983541 scopus 로고    scopus 로고
    • Activity of the phosphatidylcholine biosynthetic pathway modulates the distribution of fatty acids into glycerolipids in proliferating cells
    • 10.1016/S1388-1981(99)00203-6, 10666565
    • Jackowski S, Wang J, Baburina I. Activity of the phosphatidylcholine biosynthetic pathway modulates the distribution of fatty acids into glycerolipids in proliferating cells. Biochim Biophys Acta 2000, 1483(3):301-315. 10.1016/S1388-1981(99)00203-6, 10666565.
    • (2000) Biochim Biophys Acta , vol.1483 , Issue.3 , pp. 301-315
    • Jackowski, S.1    Wang, J.2    Baburina, I.3
  • 44
    • 0037047112 scopus 로고    scopus 로고
    • C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity
    • 123169, 12060712
    • Thupari JN, Landree LE, Ronnett GV, Kuhajda FP. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proc Natl Acad Sci U S A 2002, 99(14):9498-9502. 123169, 12060712.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.14 , pp. 9498-9502
    • Thupari, J.N.1    Landree, L.E.2    Ronnett, G.V.3    Kuhajda, F.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.