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Volumn 5, Issue 10, 2015, Pages 1122-1143

Micrornas: New biomarkers for diagnosis, prognosis, therapy prediction and therapeutic tools for breast cancer

Author keywords

Breast cancer; Circulating biomarker; Diagnosis; Microrna mirna; Prediction and therapy; Prognosis; Theranostic

Indexed keywords

ANTINEOPLASTIC AGENT; BIOLOGICAL MARKER; DAUNORUBICIN; MICRORNA; MICRORNA 10B; MICRORNA 145; MICRORNA 148A; MICRORNA 150; MICRORNA 155; MICRORNA 17 5P; MICRORNA 187; MICRORNA 195; MICRORNA 200C; MICRORNA 203; MICRORNA 206; MICRORNA 21; MICRORNA 210; MICRORNA 30C; MICRORNA 335; MICRORNA 339 5P; MICRORNA 34A; MICRORNA 9; MICRORNA 92A; MICRORNA LET 7; MRX 34; UNCLASSIFIED DRUG; TUMOR MARKER;

EID: 84942523631     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.11543     Document Type: Article
Times cited : (689)

References (247)
  • 1
    • 0027751663 scopus 로고
    • elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75: 843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3    The, C.4
  • 2
    • 84880770383 scopus 로고    scopus 로고
    • Diversifying microRNA sequence and function
    • Ameres SL, Zamore PD. Diversifying microRNA sequence and function. Nat Rev Mol Cell Biol 2013; 14: 475-488.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 475-488
    • Ameres, S.L.1    Zamore, P.D.2
  • 3
    • 84891818318 scopus 로고    scopus 로고
    • miRBase: annotating high confidence microRNAs using deep sequencing data
    • Kozomara A, Griffiths-Jones S. miRBase: annotating high confidence microRNAs using deep sequencing data. Nucleic Acids Res 2014; 42: D68-73.
    • (2014) Nucleic Acids Res , vol.42 , pp. D68-73
    • Kozomara, A.1    Griffiths-Jones, S.2
  • 4
  • 5
    • 77954517267 scopus 로고    scopus 로고
    • MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems
    • Herranz H, Cohen SM. MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems. Genes Dev 2010; 24: 1339-1344.
    • (2010) Genes Dev , vol.24 , pp. 1339-1344
    • Herranz, H.1    Cohen, S.M.2
  • 6
    • 84926480089 scopus 로고    scopus 로고
    • The emerging role of microRNAs in Alzheimer's disease
    • Femminella GD, Ferrara N, Rengo G. The emerging role of microRNAs in Alzheimer's disease. Front Physiol 2015; 6: 40.
    • (2015) Front Physiol , vol.6 , pp. 40
    • Femminella, G.D.1    Ferrara, N.2    Rengo, G.3
  • 7
    • 84924260735 scopus 로고    scopus 로고
    • Utility of Circulating MicroRNAs as Clinical Biomarkers for Cardiovascular Diseases
    • Kondkar AA, Abu-Amero KK. Utility of Circulating MicroRNAs as Clinical Biomarkers for Cardiovascular Diseases. Biomed Res Int 2015; 2015: 821823.
    • (2015) Biomed Res Int , vol.2015
    • Kondkar, A.A.1    Abu-Amero, K.K.2
  • 8
    • 84885042182 scopus 로고    scopus 로고
    • microRNA in the development of diabetic complications
    • McClelland AD, Kantharidis P. microRNA in the development of diabetic complications. Clin Sci (Lond) 2014; 126: 95-110.
    • (2014) Clin Sci (Lond) , vol.126 , pp. 95-110
    • McClelland, A.D.1    Kantharidis, P.2
  • 9
    • 79960104144 scopus 로고    scopus 로고
    • MicroRNAs in development and disease
    • Sayed D, Abdellatif M. MicroRNAs in development and disease. Physiol Rev 2011; 91: 827-887.
    • (2011) Physiol Rev , vol.91 , pp. 827-887
    • Sayed, D.1    Abdellatif, M.2
  • 10
    • 80051750488 scopus 로고    scopus 로고
    • Mechanisms and role of microRNA deregulation in cancer onset and progression
    • Palmero EI, de Campos SG, Campos M, et al. Mechanisms and role of microRNA deregulation in cancer onset and progression. Genet Mol Biol 2011; 34: 363-370.
    • (2011) Genet Mol Biol , vol.34 , pp. 363-370
    • Palmero, E.I.1    de Campos, S.G.2    Campos, M.3
  • 11
    • 84918815964 scopus 로고    scopus 로고
    • Cancer incidence and mortality worldwide: sources methods and major patterns in GLOBOCAN 2012
    • Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015; 136: E359-386.
    • (2015) Int J Cancer , vol.136 , pp. E359-386
    • Ferlay, J.1    Soerjomataram, I.2    Dikshit, R.3
  • 12
    • 47549084990 scopus 로고    scopus 로고
    • Histologic grading is an independent prognostic factor in invasive lobular carcinoma of the breast
    • Rakha EA, El-Sayed ME, Menon S, et al. Histologic grading is an independent prognostic factor in invasive lobular carcinoma of the breast. Breast Cancer Res Treat 2008; 111: 121-127.
    • (2008) Breast Cancer Res Treat , vol.111 , pp. 121-127
    • Rakha, E.A.1    El-Sayed, M.E.2    Menon, S.3
  • 13
    • 84866765384 scopus 로고    scopus 로고
    • The current state of breast cancer classification
    • Viale G. The current state of breast cancer classification. Ann Oncol 2012; 23 Suppl 10: x207-210.
    • (2012) Ann Oncol , vol.23 , pp. x207-210
    • Viale, G.1
  • 14
    • 0036731788 scopus 로고    scopus 로고
    • Revision of the American Joint Committee on Cancer staging system for breast cancer
    • Singletary SE, Allred C, Ashley P, et al. Revision of the American Joint Committee on Cancer staging system for breast cancer. J Clin Oncol 2002; 20: 3628-3636.
    • (2002) J Clin Oncol , vol.20 , pp. 3628-3636
    • Singletary, S.E.1    Allred, C.2    Ashley, P.3
  • 15
    • 77951981110 scopus 로고    scopus 로고
    • Classification and prognosis of invasive breast cancer: from morphology to molecular taxonomy
    • Schnitt SJ. Classification and prognosis of invasive breast cancer: from morphology to molecular taxonomy. Mod Pathol 2010; 23 Suppl 2: S60-64.
    • (2010) Mod Pathol , vol.23 , pp. S60-64
    • Schnitt, S.J.1
  • 16
    • 33746050690 scopus 로고    scopus 로고
    • A clinical prognostic prediction of lymph node-negative breast cancer by gene expression profiles
    • Jiang D, Zhao N. A clinical prognostic prediction of lymph node-negative breast cancer by gene expression profiles. J Cancer Res Clin Oncol 2006; 132: 579-587.
    • (2006) J Cancer Res Clin Oncol , vol.132 , pp. 579-587
    • Jiang, D.1    Zhao, N.2
  • 17
    • 84872496432 scopus 로고    scopus 로고
    • MicroRNAs as potential biomarkers in human solid tumors
    • Shen J, Stass SA, Jiang F. MicroRNAs as potential biomarkers in human solid tumors. Cancer Lett 2013; 329: 125-136.
    • (2013) Cancer Lett , vol.329 , pp. 125-136
    • Shen, J.1    Stass, S.A.2    Jiang, F.3
  • 18
    • 84863229464 scopus 로고    scopus 로고
    • Circulating miRNAs: promising biomarkers of human cancer
    • Qu H, Xu W, Huang Y, Yang S. Circulating miRNAs: promising biomarkers of human cancer. Asian Pac J Cancer Prev 2011; 12: 1117-1125.
    • (2011) Asian Pac J Cancer Prev , vol.12 , pp. 1117-1125
    • Qu, H.1    Xu, W.2    Huang, Y.3    Yang, S.4
  • 19
    • 84912063255 scopus 로고    scopus 로고
    • Distribution profiling of circulating microRNAs in serum
    • Ashby J, Flack K, Jimenez LA, et al. Distribution profiling of circulating microRNAs in serum. Anal Chem 2014; 86: 9343-9349.
    • (2014) Anal Chem , vol.86 , pp. 9343-9349
    • Ashby, J.1    Flack, K.2    Jimenez, L.A.3
  • 20
    • 79953202200 scopus 로고    scopus 로고
    • Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
    • Arroyo JD, Chevillet JR, Kroh EM, et al. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci U S A 2011; 108: 5003-5008.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 5003-5008
    • Arroyo, J.D.1    Chevillet, J.R.2    Kroh, E.M.3
  • 21
    • 84901441961 scopus 로고    scopus 로고
    • Integration of mRNA expression profile, copy number alterations, and microRNA expression levels in breast cancer to improve grade definition
    • Cava C, Bertoli G, Ripamonti M, et al. Integration of mRNA expression profile, copy number alterations, and microRNA expression levels in breast cancer to improve grade definition. PLoS One 2014; 9: e97681.
    • (2014) PLoS One , vol.9
    • Cava, C.1    Bertoli, G.2    Ripamonti, M.3
  • 22
    • 84904985459 scopus 로고    scopus 로고
    • Regulation of microRNA biogenesis
    • Ha M, Kim VN. Regulation of microRNA biogenesis. Nat Rev Mol Cell Biol 2014; 15: 509-524.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 509-524
    • Ha, M.1    Kim, V.N.2
  • 23
    • 84907587666 scopus 로고    scopus 로고
    • Down-regulation of the antisense mitochondrial non-coding RNAs (ncRNAs) is a unique vulnerability of cancer cells and a potential target for cancer therapy
    • Vidaurre S, Fitzpatrick C, Burzio VA, et al. Down-regulation of the antisense mitochondrial non-coding RNAs (ncRNAs) is a unique vulnerability of cancer cells and a potential target for cancer therapy. J Biol Chem 2014; 289: 27182-27198.
    • (2014) J Biol Chem , vol.289 , pp. 27182-27198
    • Vidaurre, S.1    Fitzpatrick, C.2    Burzio, V.A.3
  • 24
    • 78650306521 scopus 로고    scopus 로고
    • Small RNA sorting: matchmaking for Argonautes
    • Czech B, Hannon GJ. Small RNA sorting: matchmaking for Argonautes. Nat Rev Genet 2011; 12: 19-31.
    • (2011) Nat Rev Genet , vol.12 , pp. 19-31
    • Czech, B.1    Hannon, G.J.2
  • 25
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • Lee Y, Ahn C, Han J, et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003; 425: 415-419.
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1    Ahn, C.2    Han, J.3
  • 26
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the Microprocessor complex
    • Denli AM, Tops BB, Plasterk RH, et al. Processing of primary microRNAs by the Microprocessor complex. Nature 2004; 432: 231-235.
    • (2004) Nature , vol.432 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.2    Plasterk, R.H.3
  • 27
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 2003; 17: 3011-3016.
    • (2003) Genes Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 28
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • Bohnsack MT, Czaplinski K, Gorlich D. Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 2004; 10: 185-191.
    • (2004) RNA , vol.10 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 29
    • 0347988235 scopus 로고    scopus 로고
    • Nuclear export of microRNA precursors
    • Lund E, Guttinger S, Calado A, et al. Nuclear export of microRNA precursors. Science 2004; 303: 95-98.
    • (2004) Science , vol.303 , pp. 95-98
    • Lund, E.1    Guttinger, S.2    Calado, A.3
  • 30
    • 36849048778 scopus 로고    scopus 로고
    • Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression
    • Diederichs S, Haber DA. Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell 2007; 131: 1097-1108.
    • (2007) Cell , vol.131 , pp. 1097-1108
    • Diederichs, S.1    Haber, D.A.2
  • 31
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 32
    • 70449122099 scopus 로고    scopus 로고
    • Distinct mechanisms for microRNA strand selection by Drosophila Argonautes
    • Okamura K, Liu N, Lai EC. Distinct mechanisms for microRNA strand selection by Drosophila Argonautes. Mol Cell 2009; 36: 431-444.
    • (2009) Mol Cell , vol.36 , pp. 431-444
    • Okamura, K.1    Liu, N.2    Lai, E.C.3
  • 33
    • 75649129754 scopus 로고    scopus 로고
    • Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
    • Ghildiyal M, Xu J, Seitz H, et al. Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway. RNA 2010; 16: 43-56.
    • (2010) RNA , vol.16 , pp. 43-56
    • Ghildiyal, M.1    Xu, J.2    Seitz, H.3
  • 34
    • 43449090367 scopus 로고    scopus 로고
    • MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation
    • Orom UA, Nielsen FC, Lund AH. MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell 2008; 30: 460-471.
    • (2008) Mol Cell , vol.30 , pp. 460-471
    • Orom, U.A.1    Nielsen, F.C.2    Lund, A.H.3
  • 35
    • 77949731645 scopus 로고    scopus 로고
    • miR-24 regulates apoptosis by targeting the open reading frame (ORF) region of FAF1 in cancer cells
    • Qin W, Shi Y, Zhao B, et al. miR-24 regulates apoptosis by targeting the open reading frame (ORF) region of FAF1 in cancer cells. PLoS One 2010; 5: e9429.
    • (2010) PLoS One , vol.5
    • Qin, W.1    Shi, Y.2    Zhao, B.3
  • 36
    • 34547441263 scopus 로고    scopus 로고
    • Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR
    • Lytle JR, Yario TA, Steitz JA. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR. Proc Natl Acad Sci U S A 2007; 104: 9667-9672.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 9667-9672
    • Lytle, J.R.1    Yario, T.A.2    Steitz, J.A.3
  • 37
    • 77649133970 scopus 로고    scopus 로고
    • miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts
    • Eiring AM, Harb JG, Neviani P, et al. miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell 2010; 140: 652-665.
    • (2010) Cell , vol.140 , pp. 652-665
    • Eiring, A.M.1    Harb, J.G.2    Neviani, P.3
  • 38
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: microRNAs can up-regulate translation
    • Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: microRNAs can up-regulate translation. Science 2007; 318: 1931-1934.
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 39
    • 84920067895 scopus 로고    scopus 로고
    • Computational Methods for MicroRNA Target Prediction
    • Ekimler S, Sahin K. Computational Methods for MicroRNA Target Prediction. Genes (Basel) 2014; 5: 671-683.
    • (2014) Genes (Basel) , vol.5 , pp. 671-683
    • Ekimler, S.1    Sahin, K.2
  • 40
    • 0346094457 scopus 로고    scopus 로고
    • Prediction of mammalian microRNA targets
    • Lewis BP, Shih IH, Jones-Rhoades MW, et al. Prediction of mammalian microRNA targets. Cell 2003; 115: 787-798.
    • (2003) Cell , vol.115 , pp. 787-798
    • Lewis, B.P.1    Shih, I.H.2    Jones-Rhoades, M.W.3
  • 41
    • 77950920903 scopus 로고    scopus 로고
    • Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
    • Hafner M, Landthaler M, Burger L, et al. Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 2010; 141: 129-141.
    • (2010) Cell , vol.141 , pp. 129-141
    • Hafner, M.1    Landthaler, M.2    Burger, L.3
  • 42
    • 80053197539 scopus 로고    scopus 로고
    • Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing
    • Broderick JA, Salomon WE, Ryder SP, et al. Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing. RNA 2011; 17: 1858-1869.
    • (2011) RNA , vol.17 , pp. 1858-1869
    • Broderick, J.A.1    Salomon, W.E.2    Ryder, S.P.3
  • 43
    • 22844440427 scopus 로고    scopus 로고
    • Identification of hundreds of conserved and nonconserved human microRNAs
    • Bentwich I, Avniel A, Karov Y, et al. Identification of hundreds of conserved and nonconserved human microRNAs. Nat Genet 2005; 37: 766-770.
    • (2005) Nat Genet , vol.37 , pp. 766-770
    • Bentwich, I.1    Avniel, A.2    Karov, Y.3
  • 44
    • 70450172473 scopus 로고    scopus 로고
    • Survey of Computational Algorithms for MicroRNA Target Prediction
    • Yue D, Liu H, Huang Y. Survey of Computational Algorithms for MicroRNA Target Prediction. Curr Genomics 2009; 10: 478-492.
    • (2009) Curr Genomics , vol.10 , pp. 478-492
    • Yue, D.1    Liu, H.2    Huang, Y.3
  • 45
    • 34748865410 scopus 로고    scopus 로고
    • How microRNAs choose their targets
    • Hofacker IL. How microRNAs choose their targets. Nat Genet 2007; 39: 1191-1192.
    • (2007) Nat Genet , vol.39 , pp. 1191-1192
    • Hofacker, I.L.1
  • 46
    • 34748821761 scopus 로고    scopus 로고
    • The role of site accessibility in microRNA target recognition
    • Kertesz M, Iovino N, Unnerstall U, et al. The role of site accessibility in microRNA target recognition. Nat Genet 2007; 39: 1278-1284.
    • (2007) Nat Genet , vol.39 , pp. 1278-1284
    • Kertesz, M.1    Iovino, N.2    Unnerstall, U.3
  • 47
    • 34249003938 scopus 로고    scopus 로고
    • Principles and limitations of computational microRNA gene and target finding
    • Lindow M, Gorodkin J. Principles and limitations of computational microRNA gene and target finding. DNA Cell Biol 2007; 26: 339-351.
    • (2007) DNA Cell Biol , vol.26 , pp. 339-351
    • Lindow, M.1    Gorodkin, J.2
  • 48
    • 84876136646 scopus 로고    scopus 로고
    • Computational methods for ab initio detection of microRNAs
    • Allmer J, Yousef M. Computational methods for ab initio detection of microRNAs. Front Genet 2012; 3: 209.
    • (2012) Front Genet , vol.3 , pp. 209
    • Allmer, J.1    Yousef, M.2
  • 49
    • 33750416896 scopus 로고    scopus 로고
    • PSoL: a positive sample only learning algorithm for finding non-coding RNA genes
    • Wang C, Ding C, Meraz RF, Holbrook SR. PSoL: a positive sample only learning algorithm for finding non-coding RNA genes. Bioinformatics 2006; 22: 2590-2596.
    • (2006) Bioinformatics , vol.22 , pp. 2590-2596
    • Wang, C.1    Ding, C.2    Meraz, R.F.3    Holbrook, S.R.4
  • 50
    • 43949125230 scopus 로고    scopus 로고
    • Learning from positive examples when the negative class is undetermined--microRNA gene identification
    • Yousef M, Jung S, Showe LC, Showe MK. Learning from positive examples when the negative class is undetermined--microRNA gene identification. Algorithms Mol Biol 2008; 3: 2.
    • (2008) Algorithms Mol Biol , vol.3 , pp. 2
    • Yousef, M.1    Jung, S.2    Showe, L.C.3    Showe, M.K.4
  • 51
    • 60849085436 scopus 로고    scopus 로고
    • HHMMiR: efficient de novo prediction of microRNAs using hierarchical hidden Markov models
    • Kadri S, Hinman V, Benos PV. HHMMiR: efficient de novo prediction of microRNAs using hierarchical hidden Markov models. BMC Bioinformatics 2009; 10 Suppl 1: S35.
    • (2009) BMC Bioinformatics , vol.10 , pp. S35
    • Kadri, S.1    Hinman, V.2    Benos, P.V.3
  • 52
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • Krek A, Grun D, Poy MN, et al. Combinatorial microRNA target predictions. Nat Genet 2005; 37: 495-500.
    • (2005) Nat Genet , vol.37 , pp. 495-500
    • Krek, A.1    Grun, D.2    Poy, M.N.3
  • 53
    • 38349097919 scopus 로고    scopus 로고
    • MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans
    • Huang TH, Fan B, Rothschild MF, et al. MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans. BMC Bioinformatics 2007; 8: 341.
    • (2007) BMC Bioinformatics , vol.8 , pp. 341
    • Huang, T.H.1    Fan, B.2    Rothschild, M.F.3
  • 54
    • 33747871855 scopus 로고    scopus 로고
    • Hairpins in a Haystack: recognizing microRNA precursors in comparative genomics data
    • Hertel J, Stadler PF. Hairpins in a Haystack: recognizing microRNA precursors in comparative genomics data. Bioinformatics 2006; 22: e197-202.
    • (2006) Bioinformatics , vol.22 , pp. e197-202
    • Hertel, J.1    Stadler, P.F.2
  • 55
    • 21844477027 scopus 로고    scopus 로고
    • Human microRNA prediction through a probabilistic co-learning model of sequence and structure
    • Nam JW, Shin KR, Han J, et al. Human microRNA prediction through a probabilistic co-learning model of sequence and structure. Nucleic Acids Res 2005; 33: 3570-3581.
    • (2005) Nucleic Acids Res , vol.33 , pp. 3570-3581
    • Nam, J.W.1    Shin, K.R.2    Han, J.3
  • 56
    • 36249010340 scopus 로고    scopus 로고
    • miRRim: a novel system to find conserved miRNAs with high sensitivity and specificity
    • Terai G, Komori T, Asai K, Kin T. miRRim: a novel system to find conserved miRNAs with high sensitivity and specificity. RNA 2007; 13: 2081-2090.
    • (2007) RNA , vol.13 , pp. 2081-2090
    • Terai, G.1    Komori, T.2    Asai, K.3    Kin, T.4
  • 57
    • 33745594057 scopus 로고    scopus 로고
    • Combining multi-species genomic data for microRNA identification using a Naive Bayes classifier
    • Yousef M, Nebozhyn M, Shatkay H, et al. Combining multi-species genomic data for microRNA identification using a Naive Bayes classifier. Bioinformatics 2006; 22: 1325-1334.
    • (2006) Bioinformatics , vol.22 , pp. 1325-1334
    • Yousef, M.1    Nebozhyn, M.2    Shatkay, H.3
  • 58
    • 67249093200 scopus 로고    scopus 로고
    • Prediction of novel microRNA genes in cancer-associated genomic regions--a combined computational and experimental approach
    • Oulas A, Boutla A, Gkirtzou K, et al. Prediction of novel microRNA genes in cancer-associated genomic regions--a combined computational and experimental approach. Nucleic Acids Res 2009; 37: 3276-3287.
    • (2009) Nucleic Acids Res , vol.37 , pp. 3276-3287
    • Oulas, A.1    Boutla, A.2    Gkirtzou, K.3
  • 59
    • 70449372292 scopus 로고    scopus 로고
    • Accurate microRNA target prediction correlates with protein repression levels
    • Maragkakis M, Alexiou P, Papadopoulos GL, et al. Accurate microRNA target prediction correlates with protein repression levels. BMC Bioinformatics 2009; 10: 295.
    • (2009) BMC Bioinformatics , vol.10 , pp. 295
    • Maragkakis, M.1    Alexiou, P.2    Papadopoulos, G.L.3
  • 61
    • 37349042903 scopus 로고    scopus 로고
    • Experimental validation of miRNA targets
    • Kuhn DE, Martin MM, Feldman DS, et al. Experimental validation of miRNA targets. Methods 2008; 44: 47-54.
    • (2008) Methods , vol.44 , pp. 47-54
    • Kuhn, D.E.1    Martin, M.M.2    Feldman, D.S.3
  • 62
    • 80052451056 scopus 로고    scopus 로고
    • Experimental strategies for microRNA target identification
    • Thomson DW, Bracken CP, Goodall GJ. Experimental strategies for microRNA target identification. Nucleic Acids Res 2011; 39: 6845-6853.
    • (2011) Nucleic Acids Res , vol.39 , pp. 6845-6853
    • Thomson, D.W.1    Bracken, C.P.2    Goodall, G.J.3
  • 64
    • 37648999735 scopus 로고    scopus 로고
    • A biochemical approach to identifying microRNA targets
    • Karginov FV, Conaco C, Xuan Z, et al. A biochemical approach to identifying microRNA targets. Proc Natl Acad Sci U S A 2007; 104: 19291-19296.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19291-19296
    • Karginov, F.V.1    Conaco, C.2    Xuan, Z.3
  • 65
    • 84870936544 scopus 로고    scopus 로고
    • Capturing microRNA targets using an RNA-induced silencing complex (RISC)-trap approach
    • Cambronne XA, Shen R, Auer PL, Goodman RH. Capturing microRNA targets using an RNA-induced silencing complex (RISC)-trap approach. Proc Natl Acad Sci U S A 2012; 109: 20473-20478.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 20473-20478
    • Cambronne, X.A.1    Shen, R.2    Auer, P.L.3    Goodman, R.H.4
  • 66
    • 79958767367 scopus 로고    scopus 로고
    • MicroRNA signatures: clinical biomarkers for the diagnosis and treatment of breast cancer
    • Andorfer CA, Necela BM, Thompson EA, Perez EA. MicroRNA signatures: clinical biomarkers for the diagnosis and treatment of breast cancer. Trends Mol Med 2011; 17: 313-319.
    • (2011) Trends Mol Med , vol.17 , pp. 313-319
    • Andorfer, C.A.1    Necela, B.M.2    Thompson, E.A.3    Perez, E.A.4
  • 67
    • 65649110800 scopus 로고    scopus 로고
    • MicroRNA expression and its implications for the diagnosis and therapeutic strategies of breast cancer
    • Shi M, Guo N. MicroRNA expression and its implications for the diagnosis and therapeutic strategies of breast cancer. Cancer Treat Rev 2009; 35: 328-334.
    • (2009) Cancer Treat Rev , vol.35 , pp. 328-334
    • Shi, M.1    Guo, N.2
  • 68
    • 67651002343 scopus 로고    scopus 로고
    • Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell
    • Sotiropoulou G, Pampalakis G, Lianidou E, Mourelatos Z. Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. RNA 2009; 15: 1443-1461.
    • (2009) RNA , vol.15 , pp. 1443-1461
    • Sotiropoulou, G.1    Pampalakis, G.2    Lianidou, E.3    Mourelatos, Z.4
  • 69
    • 34248217444 scopus 로고    scopus 로고
    • Methylation of human microRNA genes in normal and neoplastic cells
    • Weber B, Stresemann C, Brueckner B, Lyko F. Methylation of human microRNA genes in normal and neoplastic cells. Cell Cycle 2007; 6: 1001-1005.
    • (2007) Cell Cycle , vol.6 , pp. 1001-1005
    • Weber, B.1    Stresemann, C.2    Brueckner, B.3    Lyko, F.4
  • 70
    • 84902253414 scopus 로고    scopus 로고
    • Aberrant DNA methylation of microRNA genes in human breast cancer -a critical appraisal
    • Lehmann U. Aberrant DNA methylation of microRNA genes in human breast cancer - a critical appraisal. Cell Tissue Res 2014; 356: 657-664.
    • (2014) Cell Tissue Res , vol.356 , pp. 657-664
    • Lehmann, U.1
  • 71
    • 84868100929 scopus 로고    scopus 로고
    • MicroRNA-200 family modulation in distinct breast cancer phenotypes
    • Castilla MA, Diaz-Martin J, Sarrio D, et al. MicroRNA-200 family modulation in distinct breast cancer phenotypes. PLoS One 2012; 7: e47709.
    • (2012) PLoS One , vol.7
    • Castilla, M.A.1    Diaz-Martin, J.2    Sarrio, D.3
  • 72
    • 84866550833 scopus 로고    scopus 로고
    • Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer
    • Wee EJ, Peters K, Nair SS, et al. Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer. Oncogene 2012; 31: 4182-4195.
    • (2012) Oncogene , vol.31 , pp. 4182-4195
    • Wee, E.J.1    Peters, K.2    Nair, S.S.3
  • 73
    • 84887706233 scopus 로고    scopus 로고
    • Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
    • Aure MR, Leivonen SK, Fleischer T, et al. Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors. Genome Biol 2013; 14: R126.
    • (2013) Genome Biol , vol.14
    • Aure, M.R.1    Leivonen, S.K.2    Fleischer, T.3
  • 74
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • Saito Y, Liang G, Egger G, et al. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006; 9: 435-443.
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3
  • 75
    • 32944462300 scopus 로고    scopus 로고
    • Rapid alteration of microRNA levels by histone deacetylase inhibition
    • Scott GK, Mattie MD, Berger CE, et al. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res 2006; 66: 1277-1281.
    • (2006) Cancer Res , vol.66 , pp. 1277-1281
    • Scott, G.K.1    Mattie, M.D.2    Berger, C.E.3
  • 76
    • 84863092406 scopus 로고    scopus 로고
    • Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer
    • Yamamoto H, Adachi Y, Taniguchi H, et al. Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer. World J Gastroenterol 2012; 18: 2745-2755.
    • (2012) World J Gastroenterol , vol.18 , pp. 2745-2755
    • Yamamoto, H.1    Adachi, Y.2    Taniguchi, H.3
  • 77
    • 84899102633 scopus 로고    scopus 로고
    • Up-regulation and worse prognostic marker of cytoplasmic TARBP2 expression in obstinate breast cancer
    • Lin X, Wu M, Liu P, et al. Up-regulation and worse prognostic marker of cytoplasmic TARBP2 expression in obstinate breast cancer. Med Oncol 2014; 31: 868.
    • (2014) Med Oncol , vol.31 , pp. 868
    • Lin, X.1    Wu, M.2    Liu, P.3
  • 78
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 2004; 101: 2999-3004.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3
  • 79
    • 0034708122 scopus 로고    scopus 로고
    • The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
    • Reinhart BJ, Slack FJ, Basson M, et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 2000; 403: 901-906.
    • (2000) Nature , vol.403 , pp. 901-906
    • Reinhart, B.J.1    Slack, F.J.2    Basson, M.3
  • 80
    • 84871780605 scopus 로고    scopus 로고
    • The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients
    • Khoshnaw SM, Rakha EA, Abdel-Fatah T, et al. The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients. Breast Cancer Res Treat 2013; 137: 139-153.
    • (2013) Breast Cancer Res Treat , vol.137 , pp. 139-153
    • Khoshnaw, S.M.1    Rakha, E.A.2    Abdel-Fatah, T.3
  • 81
    • 84866549607 scopus 로고    scopus 로고
    • Loss of Dicer expression is associated with breast cancer progression and recurrence
    • Khoshnaw SM, Rakha EA, Abdel-Fatah TM, et al. Loss of Dicer expression is associated with breast cancer progression and recurrence. Breast Cancer Res Treat 2012; 135: 403-413.
    • (2012) Breast Cancer Res Treat , vol.135 , pp. 403-413
    • Khoshnaw, S.M.1    Rakha, E.A.2    Abdel-Fatah, T.M.3
  • 82
    • 84863452911 scopus 로고    scopus 로고
    • Dysregulated expression of dicer and drosha in breast cancer
    • Yan M, Huang HY, Wang T, et al. Dysregulated expression of dicer and drosha in breast cancer. Pathol Oncol Res 2012; 18: 343-348.
    • (2012) Pathol Oncol Res , vol.18 , pp. 343-348
    • Yan, M.1    Huang, H.Y.2    Wang, T.3
  • 83
    • 78650420261 scopus 로고    scopus 로고
    • Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer
    • Dedes KJ, Natrajan R, Lambros MB, et al. Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer. Eur J Cancer 2011; 47: 138-150.
    • (2011) Eur J Cancer , vol.47 , pp. 138-150
    • Dedes, K.J.1    Natrajan, R.2    Lambros, M.B.3
  • 84
    • 84872264446 scopus 로고    scopus 로고
    • Inducing cell proliferation inhibition and apoptosis via silencing Dicer, Drosha, and Exportin 5 in urothelial carcinoma of the bladder
    • Han Y, Liu Y, Gui Y, Cai Z. Inducing cell proliferation inhibition and apoptosis via silencing Dicer, Drosha, and Exportin 5 in urothelial carcinoma of the bladder. J Surg Oncol 2013; 107: 201-205.
    • (2013) J Surg Oncol , vol.107 , pp. 201-205
    • Han, Y.1    Liu, Y.2    Gui, Y.3    Cai, Z.4
  • 85
    • 84927798004 scopus 로고    scopus 로고
    • Down-regulation of Dicer and Ago2 is associated with cell proliferation and apoptosis in prostate cancer
    • Bian XJ, Zhang GM, Gu CY, et al. Down-regulation of Dicer and Ago2 is associated with cell proliferation and apoptosis in prostate cancer. Tumour Biol 2014; 35: 11571-11578.
    • (2014) Tumour Biol , vol.35 , pp. 11571-11578
    • Bian, X.J.1    Zhang, G.M.2    Gu, C.Y.3
  • 86
    • 84899534662 scopus 로고    scopus 로고
    • Dysregulation of microRNA biosynthesis enzyme Dicer plays an important role in gastric cancer progression
    • Zhang J, Zhang XH, Wang CX, et al. Dysregulation of microRNA biosynthesis enzyme Dicer plays an important role in gastric cancer progression. Int J Clin Exp Pathol 2014; 7: 1702-1707.
    • (2014) Int J Clin Exp Pathol , vol.7 , pp. 1702-1707
    • Zhang, J.1    Zhang, X.H.2    Wang, C.X.3
  • 87
    • 84906279797 scopus 로고    scopus 로고
    • Up-regulated expression of Dicer reveals poor prognosis in laryngeal squamous cell carcinoma
    • Gao C, Li X, Tong B, et al. Up-regulated expression of Dicer reveals poor prognosis in laryngeal squamous cell carcinoma. Acta Otolaryngol 2014; 134: 959-963.
    • (2014) Acta Otolaryngol , vol.134 , pp. 959-963
    • Gao, C.1    Li, X.2    Tong, B.3
  • 88
    • 84858706563 scopus 로고    scopus 로고
    • Expression of Dicer and Drosha in triple-negative breast cancer
    • Passon N, Gerometta A, Puppin C, et al. Expression of Dicer and Drosha in triple-negative breast cancer. J Clin Pathol 2012; 65: 320-326.
    • (2012) J Clin Pathol , vol.65 , pp. 320-326
    • Passon, N.1    Gerometta, A.2    Puppin, C.3
  • 89
    • 83755171315 scopus 로고    scopus 로고
    • Nucleolin protein interacts with microprocessor complex to affect biogenesis of microRNAs 15a and 16
    • Pickering BF, Yu D, Van Dyke MW. Nucleolin protein interacts with microprocessor complex to affect biogenesis of microRNAs 15a and 16. J Biol Chem 2011; 286: 44095-44103.
    • (2011) J Biol Chem , vol.286 , pp. 44095-44103
    • Pickering, B.F.1    Yu, D.2    Van Dyke, M.W.3
  • 90
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • Davis BN, Hilyard AC, Lagna G, Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008; 454: 56-61.
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 91
    • 84879585408 scopus 로고    scopus 로고
    • In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation
    • Pichiorri F, Palmieri D, De Luca L, et al. In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation. J Exp Med 2013; 210: 951-968.
    • (2013) J Exp Med , vol.210 , pp. 951-968
    • Pichiorri, F.1    Palmieri, D.2    De Luca, L.3
  • 92
    • 34249819336 scopus 로고    scopus 로고
    • MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
    • Tsang J, Zhu J, van Oudenaarden A. MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol Cell 2007; 26: 753-767.
    • (2007) Mol Cell , vol.26 , pp. 753-767
    • Tsang, J.1    Zhu, J.2    van Oudenaarden, A.3
  • 93
    • 56649099271 scopus 로고    scopus 로고
    • Analysis of regulatory network topology reveals functionally distinct classes of microRNAs
    • Yu X, Lin J, Zack DJ, et al. Analysis of regulatory network topology reveals functionally distinct classes of microRNAs. Nucleic Acids Res 2008; 36: 6494-6503.
    • (2008) Nucleic Acids Res , vol.36 , pp. 6494-6503
    • Yu, X.1    Lin, J.2    Zack, D.J.3
  • 94
    • 28344438648 scopus 로고    scopus 로고
    • A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis
    • Fazi F, Rosa A, Fatica A, et al. A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell 2005; 123: 819-831.
    • (2005) Cell , vol.123 , pp. 819-831
    • Fazi, F.1    Rosa, A.2    Fatica, A.3
  • 95
    • 77955484492 scopus 로고    scopus 로고
    • Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
    • Davis BN, Hilyard AC, Nguyen PH, et al. Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Mol Cell 2010; 39: 373-384.
    • (2010) Mol Cell , vol.39 , pp. 373-384
    • Davis, B.N.1    Hilyard, A.C.2    Nguyen, P.H.3
  • 96
    • 67749143728 scopus 로고    scopus 로고
    • Modulation of microRNA processing by p53
    • Suzuki HI, Yamagata K, Sugimoto K, et al. Modulation of microRNA processing by p53. Nature 2009; 460: 529-533.
    • (2009) Nature , vol.460 , pp. 529-533
    • Suzuki, H.I.1    Yamagata, K.2    Sugimoto, K.3
  • 97
    • 79951500251 scopus 로고    scopus 로고
    • The ATM kinase induces microRNA biogenesis in the DNA damage response
    • Zhang X, Wan G, Berger FG, et al. The ATM kinase induces microRNA biogenesis in the DNA damage response. Mol Cell 2011; 41: 371-383.
    • (2011) Mol Cell , vol.41 , pp. 371-383
    • Zhang, X.1    Wan, G.2    Berger, F.G.3
  • 98
    • 84905708863 scopus 로고    scopus 로고
    • MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state
    • Li Y, Choi PS, Casey SC, et al. MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state. Cancer Cell 2014; 26: 262-272.
    • (2014) Cancer Cell , vol.26 , pp. 262-272
    • Li, Y.1    Choi, P.S.2    Casey, S.C.3
  • 99
    • 84861944845 scopus 로고    scopus 로고
    • BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex
    • Kawai S, Amano A. BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex. J Cell Biol 2012; 197: 201-208.
    • (2012) J Cell Biol , vol.197 , pp. 201-208
    • Kawai, S.1    Amano, A.2
  • 100
    • 84878108145 scopus 로고    scopus 로고
    • EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2
    • Shen J, Xia W, Khotskaya YB, et al. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature 2013; 497: 383-387.
    • (2013) Nature , vol.497 , pp. 383-387
    • Shen, J.1    Xia, W.2    Khotskaya, Y.B.3
  • 101
    • 84882487238 scopus 로고    scopus 로고
    • MicroRNA-510 promotes cell and tumor growth by targeting peroxiredoxin1 in breast cancer
    • Guo QJ, Mills JN, Bandurraga SG, et al. MicroRNA-510 promotes cell and tumor growth by targeting peroxiredoxin1 in breast cancer. Breast Cancer Res 2013; 15: R70.
    • (2013) Breast Cancer Res , vol.15
    • Guo, Q.J.1    Mills, J.N.2    Bandurraga, S.G.3
  • 102
    • 84863012099 scopus 로고    scopus 로고
    • MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F
    • Jurmeister S, Baumann M, Balwierz A, et al. MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. Mol Cell Biol 2012; 32: 633-651.
    • (2012) Mol Cell Biol , vol.32 , pp. 633-651
    • Jurmeister, S.1    Baumann, M.2    Balwierz, A.3
  • 103
    • 84925945103 scopus 로고    scopus 로고
    • MiR-200b expression in breast cancer: a prognostic marker and act on cell proliferation and apoptosis by targeting Sp1
    • Yao Y, Hu J, Shen Z, et al. MiR-200b expression in breast cancer: a prognostic marker and act on cell proliferation and apoptosis by targeting Sp1. J Cell Mol Med 2015.
    • (2015) J Cell Mol Med
    • Yao, Y.1    Hu, J.2    Shen, Z.3
  • 104
    • 84868193774 scopus 로고    scopus 로고
    • Comparative profiling of miRNA expression of lung adenocarcinoma cells in two-dimensional and three-dimensional cultures
    • Li C, Nguyen HT, Zhuang Y, et al. Comparative profiling of miRNA expression of lung adenocarcinoma cells in two-dimensional and three-dimensional cultures. Gene 2012; 511: 143-150.
    • (2012) Gene , vol.511 , pp. 143-150
    • Li, C.1    Nguyen, H.T.2    Zhuang, Y.3
  • 105
    • 84861537616 scopus 로고    scopus 로고
    • The microRNA expression associated with morphogenesis of breast cancer cells in three-dimensional organotypic culture
    • Nguyen HT, Li C, Lin Z, et al. The microRNA expression associated with morphogenesis of breast cancer cells in three-dimensional organotypic culture. Oncol Rep 2012; 28: 117-126.
    • (2012) Oncol Rep , vol.28 , pp. 117-126
    • Nguyen, H.T.1    Li, C.2    Lin, Z.3
  • 106
    • 80051590849 scopus 로고    scopus 로고
    • Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice
    • Pramanik D, Campbell NR, Karikari C, et al. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther 2011; 10: 1470-1480.
    • (2011) Mol Cancer Ther , vol.10 , pp. 1470-1480
    • Pramanik, D.1    Campbell, N.R.2    Karikari, C.3
  • 107
    • 84880611660 scopus 로고    scopus 로고
    • MicroRNA-143 inhibits migration and invasion of human non-small-cell lung cancer and its relative mechanism
    • Ma Q, Jiang Q, Pu Q, et al. MicroRNA-143 inhibits migration and invasion of human non-small-cell lung cancer and its relative mechanism. Int J Biol Sci 2013; 9: 680-692.
    • (2013) Int J Biol Sci , vol.9 , pp. 680-692
    • Ma, Q.1    Jiang, Q.2    Pu, Q.3
  • 108
    • 84958036033 scopus 로고    scopus 로고
    • Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer
    • Seviour EG, Sehgal V, Lu Y, et al. Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer. Oncogene 2015.
    • (2015) Oncogene
    • Seviour, E.G.1    Sehgal, V.2    Lu, Y.3
  • 109
    • 84918510448 scopus 로고    scopus 로고
    • Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models
    • Bockhorn J, Prat A, Chang YF, et al. Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models. Cancer Res 2014; 74: 7406-7417.
    • (2014) Cancer Res , vol.74 , pp. 7406-7417
    • Bockhorn, J.1    Prat, A.2    Chang, Y.F.3
  • 110
    • 83555171758 scopus 로고    scopus 로고
    • Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth
    • Yan LX, Wu QN, Zhang Y, et al. Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth. Breast Cancer Res 2011; 13: R2.
    • (2011) Breast Cancer Res , vol.13
    • Yan, L.X.1    Wu, Q.N.2    Zhang, Y.3
  • 111
    • 80051643110 scopus 로고    scopus 로고
    • Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage
    • Zhu M, Yi M, Kim CH, et al. Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage. Genome Biol 2011; 12: R77.
    • (2011) Genome Biol , vol.12
    • Zhu, M.1    Yi, M.2    Kim, C.H.3
  • 112
    • 77949658280 scopus 로고    scopus 로고
    • Regression of murine lung tumors by the let-7 microRNA
    • Trang P, Medina PP, Wiggins JF, et al. Regression of murine lung tumors by the let-7 microRNA. Oncogene 2010; 29: 1580-1587.
    • (2010) Oncogene , vol.29 , pp. 1580-1587
    • Trang, P.1    Medina, P.P.2    Wiggins, J.F.3
  • 113
    • 33646471662 scopus 로고    scopus 로고
    • Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice
    • Costinean S, Zanesi N, Pekarsky Y, et al. Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proc Natl Acad Sci U S A 2006; 103: 7024-7029.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7024-7029
    • Costinean, S.1    Zanesi, N.2    Pekarsky, Y.3
  • 114
    • 77956501846 scopus 로고    scopus 로고
    • Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21
    • Hatley ME, Patrick DM, Garcia MR, et al. Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21. Cancer Cell 2010; 18: 282-293.
    • (2010) Cancer Cell , vol.18 , pp. 282-293
    • Hatley, M.E.1    Patrick, D.M.2    Garcia, M.R.3
  • 115
    • 39749163245 scopus 로고    scopus 로고
    • Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes
    • Xiao C, Srinivasan L, Calado DP, et al. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol 2008; 9: 405-414.
    • (2008) Nat Immunol , vol.9 , pp. 405-414
    • Xiao, C.1    Srinivasan, L.2    Calado, D.P.3
  • 116
    • 73649116987 scopus 로고    scopus 로고
    • The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia
    • Klein U, Lia M, Crespo M, et al. The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia. Cancer Cell 2010; 17: 28-40.
    • (2010) Cancer Cell , vol.17 , pp. 28-40
    • Klein, U.1    Lia, M.2    Crespo, M.3
  • 117
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang KJ, Baltimore D. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A 2006; 103: 12481-12486.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 118
    • 77955435090 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression
    • Santanam U, Zanesi N, Efanov A, et al. Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression. Proc Natl Acad Sci U S A 2010; 107: 12210-12215.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 12210-12215
    • Santanam, U.1    Zanesi, N.2    Efanov, A.3
  • 119
    • 84870329756 scopus 로고    scopus 로고
    • The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy
    • O'Flaherty JD, Barr M, Fennell D, et al. The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy. J Thorac Oncol 2012; 7: 1880-1890.
    • (2012) J Thorac Oncol , vol.7 , pp. 1880-1890
    • O'Flaherty, J.D.1    Barr, M.2    Fennell, D.3
  • 120
    • 58149380742 scopus 로고    scopus 로고
    • Stem cell concepts renew cancer research
    • Dick JE. Stem cell concepts renew cancer research. Blood 2008; 112: 4793-4807.
    • (2008) Blood , vol.112 , pp. 4793-4807
    • Dick, J.E.1
  • 121
    • 84922704098 scopus 로고    scopus 로고
    • Epigenetics of cancer stem cells: Pathways and therapeutics
    • Shukla S, Meeran SM. Epigenetics of cancer stem cells: Pathways and therapeutics. Biochim Biophys Acta 2014; 1840: 3494-3502.
    • (2014) Biochim Biophys Acta , vol.1840 , pp. 3494-3502
    • Shukla, S.1    Meeran, S.M.2
  • 122
    • 84874964830 scopus 로고    scopus 로고
    • Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer
    • Si H, Sun X, Chen Y, et al. Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer. J Cancer Res Clin Oncol 2013; 139: 223-229.
    • (2013) J Cancer Res Clin Oncol , vol.139 , pp. 223-229
    • Si, H.1    Sun, X.2    Chen, Y.3
  • 123
    • 84919842021 scopus 로고    scopus 로고
    • MicroRNAs in cancer stem cells: current status and future directions
    • Chhabra R, Saini N. MicroRNAs in cancer stem cells: current status and future directions. Tumour Biol 2014; 35: 8395-8405.
    • (2014) Tumour Biol , vol.35 , pp. 8395-8405
    • Chhabra, R.1    Saini, N.2
  • 124
    • 84880670678 scopus 로고    scopus 로고
    • The Wnt-beta-catenin pathway represses let-7 microRNA expression through transactivation of Lin28 to augment breast cancer stem cell expansion
    • Cai WY, Wei TZ, Luo QC, et al. The Wnt-beta-catenin pathway represses let-7 microRNA expression through transactivation of Lin28 to augment breast cancer stem cell expansion. J Cell Sci 2013; 126: 2877-2889.
    • (2013) J Cell Sci , vol.126 , pp. 2877-2889
    • Cai, W.Y.1    Wei, T.Z.2    Luo, Q.C.3
  • 125
    • 84891048862 scopus 로고    scopus 로고
    • Targeting the epigenome in lung cancer: expanding approaches to epigenetic therapy
    • Jakopovic M, Thomas A, Balasubramaniam S, et al. Targeting the epigenome in lung cancer: expanding approaches to epigenetic therapy. Front Oncol 2013; 3: 261.
    • (2013) Front Oncol , vol.3 , pp. 261
    • Jakopovic, M.1    Thomas, A.2    Balasubramaniam, S.3
  • 126
    • 84867537443 scopus 로고    scopus 로고
    • The involvement of microRNAs in malignant transformation
    • Rutnam ZJ, Yang BB. The involvement of microRNAs in malignant transformation. Histol Histopathol 2012; 27: 1263-1270.
    • (2012) Histol Histopathol , vol.27 , pp. 1263-1270
    • Rutnam, Z.J.1    Yang, B.B.2
  • 127
    • 84863577404 scopus 로고    scopus 로고
    • Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7
    • Liu C, Kelnar K, Vlassov AV, et al. Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7. Cancer Res 2012; 72: 3393-3404.
    • (2012) Cancer Res , vol.72 , pp. 3393-3404
    • Liu, C.1    Kelnar, K.2    Vlassov, A.V.3
  • 128
    • 84905660383 scopus 로고    scopus 로고
    • Differentially expressed miRNAs in cancer-stem-like cells: markers for tumor cell aggressiveness of pancreatic cancer
    • Bao B, Ali S, Ahmad A, et al. Differentially expressed miRNAs in cancer-stem-like cells: markers for tumor cell aggressiveness of pancreatic cancer. Stem Cells Dev 2014; 23: 1947-1958.
    • (2014) Stem Cells Dev , vol.23 , pp. 1947-1958
    • Bao, B.1    Ali, S.2    Ahmad, A.3
  • 129
    • 33646045010 scopus 로고    scopus 로고
    • Stem cells and cancer: two faces of eve
    • Clarke MF, Fuller M. Stem cells and cancer: two faces of eve. Cell 2006; 124: 1111-1115.
    • (2006) Cell , vol.124 , pp. 1111-1115
    • Clarke, M.F.1    Fuller, M.2
  • 130
    • 36849078711 scopus 로고    scopus 로고
    • let-7 regulates self renewal and tumorigenicity of breast cancer cells
    • Yu F, Yao H, Zhu P, et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2007; 131: 1109-1123.
    • (2007) Cell , vol.131 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3
  • 131
    • 84877263242 scopus 로고    scopus 로고
    • A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells
    • Bu P, Chen KY, Chen JH, et al. A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells. Cell Stem Cell 2013; 12: 602-615.
    • (2013) Cell Stem Cell , vol.12 , pp. 602-615
    • Bu, P.1    Chen, K.Y.2    Chen, J.H.3
  • 132
    • 84895463099 scopus 로고    scopus 로고
    • MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells
    • Hwang WL, Jiang JK, Yang SH, et al. MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Nat Cell Biol 2014; 16: 268-280.
    • (2014) Nat Cell Biol , vol.16 , pp. 268-280
    • Hwang, W.L.1    Jiang, J.K.2    Yang, S.H.3
  • 133
    • 84862638243 scopus 로고    scopus 로고
    • Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN
    • Han M, Liu M, Wang Y, et al. Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN. PLoS One 2012; 7: e39520.
    • (2012) PLoS One , vol.7
    • Han, M.1    Liu, M.2    Wang, Y.3
  • 134
    • 84883742665 scopus 로고    scopus 로고
    • MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1
    • Yang S, Li Y, Gao J, et al. MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1. Oncogene 2013; 32: 4294-4303.
    • (2013) Oncogene , vol.32 , pp. 4294-4303
    • Yang, S.1    Li, Y.2    Gao, J.3
  • 136
    • 77956547097 scopus 로고    scopus 로고
    • Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells
    • Iliopoulos D, Lindahl-Allen M, Polytarchou C, et al. Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol Cell 2010; 39: 761-772.
    • (2010) Mol Cell , vol.39 , pp. 761-772
    • Iliopoulos, D.1    Lindahl-Allen, M.2    Polytarchou, C.3
  • 137
    • 84865973282 scopus 로고    scopus 로고
    • An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state
    • Polytarchou C, Iliopoulos D, Struhl K. An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proc Natl Acad Sci U S A 2012; 109: 14470-14475.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 14470-14475
    • Polytarchou, C.1    Iliopoulos, D.2    Struhl, K.3
  • 138
    • 73049110243 scopus 로고    scopus 로고
    • The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
    • Wellner U, Schubert J, Burk UC, et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol 2009; 11: 1487-1495.
    • (2009) Nat Cell Biol , vol.11 , pp. 1487-1495
    • Wellner, U.1    Schubert, J.2    Burk, U.C.3
  • 139
    • 85028133025 scopus 로고    scopus 로고
    • MicroRNAs and cancer stem cells: the sword and the shield
    • Sun X, Jiao X, Pestell TG, et al. MicroRNAs and cancer stem cells: the sword and the shield. Oncogene 2014; 33: 4967-4977.
    • (2014) Oncogene , vol.33 , pp. 4967-4977
    • Sun, X.1    Jiao, X.2    Pestell, T.G.3
  • 140
    • 84857898266 scopus 로고    scopus 로고
    • Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells
    • Han M, Liu M, Wang Y, et al. Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells. Mol Cell Biochem 2012; 363: 427-436.
    • (2012) Mol Cell Biochem , vol.363 , pp. 427-436
    • Han, M.1    Liu, M.2    Wang, Y.3
  • 141
    • 84863069464 scopus 로고    scopus 로고
    • miRNAs in breast cancer tumorigenesis (Review)
    • Zhang ZJ, Ma SL. miRNAs in breast cancer tumorigenesis (Review). Oncol Rep 2012; 27: 903-910.
    • (2012) Oncol Rep , vol.27 , pp. 903-910
    • Zhang, Z.J.1    Ma, S.L.2
  • 142
    • 84880223123 scopus 로고    scopus 로고
    • The role of microRNAs in breast cancer stem cells
    • Schwarzenbacher D, Balic M, Pichler M. The role of microRNAs in breast cancer stem cells. Int J Mol Sci 2013; 14: 14712-14723.
    • (2013) Int J Mol Sci , vol.14 , pp. 14712-14723
    • Schwarzenbacher, D.1    Balic, M.2    Pichler, M.3
  • 143
    • 80053406583 scopus 로고    scopus 로고
    • Heterogeneity in breast cancer
    • Polyak K. Heterogeneity in breast cancer. J Clin Invest 2011; 121: 3786-3788.
    • (2011) J Clin Invest , vol.121 , pp. 3786-3788
    • Polyak, K.1
  • 144
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature 2000; 406: 747-752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 145
    • 0035495969 scopus 로고    scopus 로고
    • Prognostic factors in breast cancer: current and new predictors of metastasis
    • Hayes DF, Isaacs C, Stearns V. Prognostic factors in breast cancer: current and new predictors of metastasis. J Mammary Gland Biol Neoplasia 2001; 6: 375-392.
    • (2001) J Mammary Gland Biol Neoplasia , vol.6 , pp. 375-392
    • Hayes, D.F.1    Isaacs, C.2    Stearns, V.3
  • 146
    • 0035865149 scopus 로고    scopus 로고
    • Computer program to assist in making decisions about adjuvant therapy for women with early breast cancer
    • Ravdin PM, Siminoff LA, Davis GJ, et al. Computer program to assist in making decisions about adjuvant therapy for women with early breast cancer. J Clin Oncol 2001; 19: 980-991.
    • (2001) J Clin Oncol , vol.19 , pp. 980-991
    • Ravdin, P.M.1    Siminoff, L.A.2    Davis, G.J.3
  • 148
    • 84870712444 scopus 로고    scopus 로고
    • A bead-based multiplexed immunoassay to evaluate breast cancer biomarkers for early detection in pre-diagnostic serum
    • Opstal-van Winden AW, Rodenburg W, Pennings JL, et al. A bead-based multiplexed immunoassay to evaluate breast cancer biomarkers for early detection in pre-diagnostic serum. Int J Mol Sci 2012; 13: 13587-13604.
    • (2012) Int J Mol Sci , vol.13 , pp. 13587-13604
    • Opstal-van Winden, A.W.1    Rodenburg, W.2    Pennings, J.L.3
  • 149
    • 84886938806 scopus 로고    scopus 로고
    • Multigene Assays for Classification, Prognosis, and Prediction in Breast Cancer: a Critical Review on the Background and Clinical Utility
    • Sinn P, Aulmann S, Wirtz R, et al. Multigene Assays for Classification, Prognosis, and Prediction in Breast Cancer: a Critical Review on the Background and Clinical Utility. Geburtshilfe Frauenheilkd 2013; 73: 932-940.
    • (2013) Geburtshilfe Frauenheilkd , vol.73 , pp. 932-940
    • Sinn, P.1    Aulmann, S.2    Wirtz, R.3
  • 150
    • 84869866890 scopus 로고    scopus 로고
    • MicroRNA and cancer
    • Jansson MD, Lund AH. MicroRNA and cancer. Mol Oncol 2012; 6: 590-610.
    • (2012) Mol Oncol , vol.6 , pp. 590-610
    • Jansson, M.D.1    Lund, A.H.2
  • 151
    • 84922061917 scopus 로고    scopus 로고
    • Use of serum-circulating miRNA profiling for the identification of breast cancer biomarkers
    • Mar-Aguilar F, Rodriguez-Padilla C, Resendez-Perez D. Use of serum-circulating miRNA profiling for the identification of breast cancer biomarkers. Methods Mol Biol 2014; 1165: 71-80.
    • (2014) Methods Mol Biol , vol.1165 , pp. 71-80
    • Mar-Aguilar, F.1    Rodriguez-Padilla, C.2    Resendez-Perez, D.3
  • 152
    • 84882968371 scopus 로고    scopus 로고
    • Identification of circulating microRNA signatures for breast cancer detection
    • Chan M, Liaw CS, Ji SM, et al. Identification of circulating microRNA signatures for breast cancer detection. Clin Cancer Res 2013; 19: 4477-4487.
    • (2013) Clin Cancer Res , vol.19 , pp. 4477-4487
    • Chan, M.1    Liaw, C.S.2    Ji, S.M.3
  • 153
    • 84907187956 scopus 로고    scopus 로고
    • miRNA as potential biomarkers of breast cancer in the Lebanese population and in young women: a pilot study
    • Nassar FJ, El Sabban M, Zgheib NK, et al. miRNA as potential biomarkers of breast cancer in the Lebanese population and in young women: a pilot study. PLoS One 2014; 9: e107566.
    • (2014) PLoS One , vol.9 , pp. e107566
    • Nassar, F.J.1    El Sabban, M.2    Zgheib, N.K.3
  • 154
    • 84904973436 scopus 로고    scopus 로고
    • The role of microRNAs in human breast cancer progression
    • Zhang W, Liu J, Wang G. The role of microRNAs in human breast cancer progression. Tumour Biol 2014; 35: 6235-6244.
    • (2014) Tumour Biol , vol.35 , pp. 6235-6244
    • Zhang, W.1    Liu, J.2    Wang, G.3
  • 155
    • 78650966289 scopus 로고    scopus 로고
    • Intracellular and extracellular microRNAs in breast cancer
    • Corcoran C, Friel AM, Duffy MJ, et al. Intracellular and extracellular microRNAs in breast cancer. Clin Chem 2011; 57: 18-32.
    • (2011) Clin Chem , vol.57 , pp. 18-32
    • Corcoran, C.1    Friel, A.M.2    Duffy, M.J.3
  • 156
    • 84875178612 scopus 로고    scopus 로고
    • MicroRNA-21 as an indicator of aggressive phenotype in breast cancer
    • Ozgun A, Karagoz B, Bilgi O, et al. MicroRNA-21 as an indicator of aggressive phenotype in breast cancer. Onkologie 2013; 36: 115-118.
    • (2013) Onkologie , vol.36 , pp. 115-118
    • Ozgun, A.1    Karagoz, B.2    Bilgi, O.3
  • 157
    • 84902064523 scopus 로고    scopus 로고
    • High expression of miR-21 in triple-negative breast cancers was correlated with a poor prognosis and promoted tumor cell in vitro proliferation
    • Dong G, Liang X, Wang D, et al. High expression of miR-21 in triple-negative breast cancers was correlated with a poor prognosis and promoted tumor cell in vitro proliferation. Med Oncol 2014; 31: 57.
    • (2014) Med Oncol , vol.31 , pp. 57
    • Dong, G.1    Liang, X.2    Wang, D.3
  • 158
    • 84870384133 scopus 로고    scopus 로고
    • Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells
    • Anastasov N, Hofig I, Vasconcellos IG, et al. Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells. Radiat Oncol 2012; 7: 206.
    • (2012) Radiat Oncol , vol.7 , pp. 206
    • Anastasov, N.1    Hofig, I.2    Vasconcellos, I.G.3
  • 159
    • 84924815453 scopus 로고    scopus 로고
    • The expression and significance of five types of miRNAs in breast cancer
    • Min W, Wang B, Li J, et al. The expression and significance of five types of miRNAs in breast cancer. Med Sci Monit Basic Res 2014; 20: 97-104.
    • (2014) Med Sci Monit Basic Res , vol.20 , pp. 97-104
    • Min, W.1    Wang, B.2    Li, J.3
  • 160
    • 84880908107 scopus 로고    scopus 로고
    • Genetic heterogeneity of breast cancer metastasis may be related to miR-21 regulation of TIMP-3 in translation
    • Li J, Zhang Y, Zhang W, et al. Genetic heterogeneity of breast cancer metastasis may be related to miR-21 regulation of TIMP-3 in translation. Int J Surg Oncol 2013; 2013: 875078.
    • (2013) Int J Surg Oncol 2013
    • Li, J.1    Zhang, Y.2    Zhang, W.3
  • 161
    • 84882344200 scopus 로고    scopus 로고
    • From microRNA functions to microRNA therapeutics: novel targets and novel drugs in breast cancer research and treatment (Review)
    • Piva R, Spandidos DA, Gambari R. From microRNA functions to microRNA therapeutics: novel targets and novel drugs in breast cancer research and treatment (Review). Int J Oncol 2013; 43: 985-994.
    • (2013) Int J Oncol , vol.43 , pp. 985-994
    • Piva, R.1    Spandidos, D.A.2    Gambari, R.3
  • 162
    • 84925457888 scopus 로고    scopus 로고
    • Micro-RNAs as clinical biomarkers and therapeutic targets in breast cancer: Quo vadis?
    • Christodoulatos GS, Dalamaga M. Micro-RNAs as clinical biomarkers and therapeutic targets in breast cancer: Quo vadis? World J Clin Oncol 2014; 5: 71-81.
    • (2014) World J Clin Oncol , vol.5 , pp. 71-81
    • Christodoulatos, G.S.1    Dalamaga, M.2
  • 163
    • 84870668442 scopus 로고    scopus 로고
    • The role of microRNAs in breast cancer migration, invasion and metastasis
    • Tang J, Ahmad A, Sarkar FH. The role of microRNAs in breast cancer migration, invasion and metastasis. Int J Mol Sci 2012; 13: 13414-13437.
    • (2012) Int J Mol Sci , vol.13 , pp. 13414-13437
    • Tang, J.1    Ahmad, A.2    Sarkar, F.H.3
  • 164
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio MV, Ferracin M, Liu CG, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005; 65: 7065-7070.
    • (2005) Cancer Res , vol.65 , pp. 7065-7070
    • Iorio, M.V.1    Ferracin, M.2    Liu, C.G.3
  • 165
    • 84965190935 scopus 로고    scopus 로고
    • Overexpression of miR-146a in basal-like breast cancer cells confers enhanced tumorigenic potential in association with altered p53 status
    • Sandhu R, Rein J, D'Arcy M, et al. Overexpression of miR-146a in basal-like breast cancer cells confers enhanced tumorigenic potential in association with altered p53 status. Carcinogenesis 2014; 35: 2567-2575.
    • (2014) Carcinogenesis , vol.35 , pp. 2567-2575
    • Sandhu, R.1    Rein, J.2    D'Arcy, M.3
  • 166
    • 84878595514 scopus 로고    scopus 로고
    • Control of metastatic progression by microRNA regulatory networks
    • Pencheva N, Tavazoie SF. Control of metastatic progression by microRNA regulatory networks. Nat Cell Biol 2013; 15: 546-554.
    • (2013) Nat Cell Biol , vol.15 , pp. 546-554
    • Pencheva, N.1    Tavazoie, S.F.2
  • 167
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007; 449: 682-688.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 168
    • 84881507602 scopus 로고    scopus 로고
    • The locus of microRNA-10b: a critical target for breast cancer insurgence and dissemination
    • Biagioni F, Bossel Ben-Moshe N, Fontemaggi G, et al. The locus of microRNA-10b: a critical target for breast cancer insurgence and dissemination. Cell Cycle 2013; 12: 2371-2375.
    • (2013) Cell Cycle , vol.12 , pp. 2371-2375
    • Biagioni, F.1    Bossel Ben-Moshe, N.2    Fontemaggi, G.3
  • 169
    • 84868336859 scopus 로고    scopus 로고
    • miR-10b*, a master inhibitor of the cell cycle, is down-regulated in human breast tumours
    • Biagioni F, Bossel Ben-Moshe N, Fontemaggi G, et al. miR-10b*, a master inhibitor of the cell cycle, is down-regulated in human breast tumours. EMBO Mol Med 2012; 4: 1214-1229.
    • (2012) EMBO Mol Med , vol.4 , pp. 1214-1229
    • Biagioni, F.1    Bossel Ben-Moshe, N.2    Fontemaggi, G.3
  • 170
    • 84925247033 scopus 로고    scopus 로고
    • Identification of microRNA-93 as a functional dysregulated miRNA in triple-negative breast cancer
    • Hu J, Xu J, Wu Y, et al. Identification of microRNA-93 as a functional dysregulated miRNA in triple-negative breast cancer. Tumour Biol 2015; 36: 251-258.
    • (2015) Tumour Biol , vol.36 , pp. 251-258
    • Hu, J.1    Xu, J.2    Wu, Y.3
  • 171
    • 84906935172 scopus 로고    scopus 로고
    • Serum microRNA-195 is down-regulated in breast cancer: a potential marker for the diagnosis of breast cancer
    • Zhao FL, Dou YC, Wang XF, et al. Serum microRNA-195 is down-regulated in breast cancer: a potential marker for the diagnosis of breast cancer. Mol Biol Rep 2014; 41: 5913-5922.
    • (2014) Mol Biol Rep , vol.41 , pp. 5913-5922
    • Zhao, F.L.1    Dou, Y.C.2    Wang, X.F.3
  • 172
    • 84862806941 scopus 로고    scopus 로고
    • MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7
    • Kim SJ, Shin JY, Lee KD, et al. MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7. Breast Cancer Res 2012; 14: R14.
    • (2012) Breast Cancer Res , vol.14
    • Kim, S.J.1    Shin, J.Y.2    Lee, K.D.3
  • 173
    • 84929502850 scopus 로고    scopus 로고
    • MicroRNA-30c-2-3p negatively regulates NF-kappaB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer
    • Shukla K, Sharma AK, Ward A, et al. MicroRNA-30c-2-3p negatively regulates NF-kappaB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer. Mol Oncol 2015.
    • Mol Oncol 2015
    • Shukla, K.1    Sharma, A.K.2    Ward, A.3
  • 174
    • 84895866794 scopus 로고    scopus 로고
    • Loss of microRNA-200a expression correlates with tumor progression in breast cancer
    • Jang K, Ahn H, Sim J, et al. Loss of microRNA-200a expression correlates with tumor progression in breast cancer. Transl Res 2014; 163: 242-251.
    • (2014) Transl Res , vol.163 , pp. 242-251
    • Jang, K.1    Ahn, H.2    Sim, J.3
  • 175
    • 84910627449 scopus 로고    scopus 로고
    • Breast cancer-specific TRAIL expression mediated by miRNA response elements of let-7 and miR-122
    • Yan Y, Zhang F, Fan Q, et al. Breast cancer-specific TRAIL expression mediated by miRNA response elements of let-7 and miR-122. Neoplasma 2014; 61: 672-679.
    • (2014) Neoplasma , vol.61 , pp. 672-679
    • Yan, Y.1    Zhang, F.2    Fan, Q.3
  • 176
    • 84902168532 scopus 로고    scopus 로고
    • Lin28B expression correlates with aggressive clinicopathological characteristics in breast invasive ductal carcinoma
    • Xie R, Wang Y, Nie W, et al. Lin28B expression correlates with aggressive clinicopathological characteristics in breast invasive ductal carcinoma. Cancer Biother Radiopharm 2014; 29: 215-220.
    • (2014) Cancer Biother Radiopharm , vol.29 , pp. 215-220
    • Xie, R.1    Wang, Y.2    Nie, W.3
  • 177
    • 50549095181 scopus 로고    scopus 로고
    • Grosshans H, let-7 microRNAs in development, stem cells and cancer
    • Bussing I, Slack FJ, Grosshans H. let-7 microRNAs in development, stem cells and cancer. Trends Mol Med 2008; 14: 400-409.
    • (2008) Trends Mol Med , vol.14 , pp. 400-409
    • Bussing, I.1    Slack, F.J.2
  • 178
    • 52949091534 scopus 로고    scopus 로고
    • The let-7 family of microRNAs
    • Roush S, Slack FJ. The let-7 family of microRNAs. Trends Cell Biol 2008; 18: 505-516.
    • (2008) Trends Cell Biol , vol.18 , pp. 505-516
    • Roush, S.1    Slack, F.J.2
  • 179
    • 84922549147 scopus 로고    scopus 로고
    • Function and regulation of let-7 family microRNAs
    • Su JL, Chen PS, Johansson G, Kuo ML. Function and regulation of let-7 family microRNAs. Microrna 2012; 1: 34-39.
    • (2012) Microrna , vol.1 , pp. 34-39
    • Su, J.L.1    Chen, P.S.2    Johansson, G.3    Kuo, M.L.4
  • 180
    • 80455174648 scopus 로고    scopus 로고
    • Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer
    • Yun J, Frankenberger CA, Kuo WL, et al. Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer. EMBO J 2011; 30: 4500-4514.
    • (2011) EMBO J , vol.30 , pp. 4500-4514
    • Yun, J.1    Frankenberger, C.A.2    Kuo, W.L.3
  • 181
    • 84891742725 scopus 로고    scopus 로고
    • The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes
    • Worringer KA, Rand TA, Hayashi Y, et al. The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes. Cell Stem Cell 2014; 14: 40-52.
    • (2014) Cell Stem Cell , vol.14 , pp. 40-52
    • Worringer, K.A.1    Rand, T.A.2    Hayashi, Y.3
  • 182
    • 84899071428 scopus 로고    scopus 로고
    • The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-kappaB
    • Jiang R, Li Y, Zhang A, et al. The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-kappaB. Toxicol Lett 2014; 227: 91-98.
    • (2014) Toxicol Lett , vol.227 , pp. 91-98
    • Jiang, R.1    Li, Y.2    Zhang, A.3
  • 183
    • 33748624597 scopus 로고    scopus 로고
    • Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies
    • Mattie MD, Benz CC, Bowers J, et al. Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol Cancer 2006; 5: 24.
    • (2006) Mol Cancer , vol.5 , pp. 24
    • Mattie, M.D.1    Benz, C.C.2    Bowers, J.3
  • 184
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, Calin GA, Liu CG, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 2006; 103: 2257-2261.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3
  • 185
    • 84896503813 scopus 로고    scopus 로고
    • MicroRNA expression signatures of stage, grade, and progression in clear cell RCC
    • Gowrishankar B, Ibragimova I, Zhou Y, et al. MicroRNA expression signatures of stage, grade, and progression in clear cell RCC. Cancer Biol Ther 2014; 15: 329-341.
    • (2014) Cancer Biol Ther , vol.15 , pp. 329-341
    • Gowrishankar, B.1    Ibragimova, I.2    Zhou, Y.3
  • 186
    • 84887492120 scopus 로고    scopus 로고
    • Meta-analysis of transcriptome reveals let-7b as an unfavorable prognostic biomarker and predicts molecular and clinical subclasses in high-grade serous ovarian carcinoma
    • Tang Z, Ow GS, Thiery JP, et al. Meta-analysis of transcriptome reveals let-7b as an unfavorable prognostic biomarker and predicts molecular and clinical subclasses in high-grade serous ovarian carcinoma. Int J Cancer 2014; 134: 306-318.
    • (2014) Int J Cancer , vol.134 , pp. 306-318
    • Tang, Z.1    Ow, G.S.2    Thiery, J.P.3
  • 187
    • 79957907561 scopus 로고    scopus 로고
    • miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1
    • Li H, Bian C, Liao L, et al. miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1. Breast Cancer Res Treat 2011; 126: 565-575.
    • (2011) Breast Cancer Res Treat , vol.126 , pp. 565-575
    • Li, H.1    Bian, C.2    Liao, L.3
  • 188
    • 84898640684 scopus 로고    scopus 로고
    • MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment
    • Leung CM, Chen TW, Li SC, et al. MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment. Oncol Rep 2014; 31: 2147-2156.
    • (2014) Oncol Rep , vol.31 , pp. 2147-2156
    • Leung, C.M.1    Chen, T.W.2    Li, S.C.3
  • 189
    • 84865975615 scopus 로고    scopus 로고
    • The extracellular-regulated protein kinase 5 (ERK5) promotes cell proliferation through the down-regulation of inhibitors of cyclin dependent protein kinases (CDKs)
    • Perez-Madrigal D, Finegan KG, Paramo B, Tournier C. The extracellular-regulated protein kinase 5 (ERK5) promotes cell proliferation through the down-regulation of inhibitors of cyclin dependent protein kinases (CDKs). Cell Signal 2012; 24: 2360-2368.
    • (2012) Cell Signal , vol.24 , pp. 2360-2368
    • Perez-Madrigal, D.1    Finegan, K.G.2    Paramo, B.3    Tournier, C.4
  • 190
    • 84893729970 scopus 로고    scopus 로고
    • MicroRNA-92a functions as an oncogene in colorectal cancer by targeting PTEN
    • Zhang G, Zhou H, Xiao H, et al. MicroRNA-92a functions as an oncogene in colorectal cancer by targeting PTEN. Dig Dis Sci 2014; 59: 98-107.
    • (2014) Dig Dis Sci , vol.59 , pp. 98-107
    • Zhang, G.1    Zhou, H.2    Xiao, H.3
  • 191
    • 84863138752 scopus 로고    scopus 로고
    • MiR-17-92 cluster regulates cell proliferation and collagen synthesis by targeting TGFB pathway in mouse palatal mesenchymal cells
    • Li L, Shi JY, Zhu GQ, Shi B. MiR-17-92 cluster regulates cell proliferation and collagen synthesis by targeting TGFB pathway in mouse palatal mesenchymal cells. J Cell Biochem 2012; 113: 1235-1244.
    • (2012) J Cell Biochem , vol.113 , pp. 1235-1244
    • Li, L.1    Shi, J.Y.2    Zhu, G.Q.3    Shi, B.4
  • 192
    • 48549099077 scopus 로고    scopus 로고
    • miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer
    • Kondo N, Toyama T, Sugiura H, et al. miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer. Cancer Res 2008; 68: 5004-5008.
    • (2008) Cancer Res , vol.68 , pp. 5004-5008
    • Kondo, N.1    Toyama, T.2    Sugiura, H.3
  • 193
    • 34250843675 scopus 로고    scopus 로고
    • The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines
    • Adams BD, Furneaux H, White BA. The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol 2007; 21: 1132-1147.
    • (2007) Mol Endocrinol , vol.21 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3
  • 194
    • 78650505163 scopus 로고    scopus 로고
    • Effect of microRNA-206 on cytoskeleton remodelling by downregulating Cdc42 in MDA-MB-231 cells
    • Liu H, Cao YD, Ye WX, Sun YY. Effect of microRNA-206 on cytoskeleton remodelling by downregulating Cdc42 in MDA-MB-231 cells. Tumori 2010; 96: 751-755.
    • (2010) Tumori , vol.96 , pp. 751-755
    • Liu, H.1    Cao, Y.D.2    Ye, W.X.3    Sun, Y.Y.4
  • 195
    • 84887330709 scopus 로고    scopus 로고
    • Decreased expression of microRNA-206 in breast cancer and its association with disease characteristics and patient survival
    • Li Y, Hong F, Yu Z. Decreased expression of microRNA-206 in breast cancer and its association with disease characteristics and patient survival. J Int Med Res 2013; 41: 596-602.
    • (2013) J Int Med Res , vol.41 , pp. 596-602
    • Li, Y.1    Hong, F.2    Yu, Z.3
  • 196
    • 84907302433 scopus 로고    scopus 로고
    • Selective repression of the oncogene cyclin D1 by the tumor suppressor miR-206 in cancers
    • Elliman SJ, Howley BV, Mehta DS, et al. Selective repression of the oncogene cyclin D1 by the tumor suppressor miR-206 in cancers. Oncogenesis 2014; 3: e113.
    • (2014) Oncogenesis , vol.3 , pp. e113
    • Elliman, S.J.1    Howley, B.V.2    Mehta, D.S.3
  • 197
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    • Shimono Y, Zabala M, Cho RW, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 2009; 138: 592-603.
    • (2009) Cell , vol.138 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3
  • 198
    • 77649275464 scopus 로고    scopus 로고
    • miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
    • Ma L, Young J, Prabhala H, et al. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol 2010; 12: 247-256.
    • (2010) Nat Cell Biol , vol.12 , pp. 247-256
    • Ma, L.1    Young, J.2    Prabhala, H.3
  • 199
    • 84902301976 scopus 로고    scopus 로고
    • Oncogenic microRNAs: miR-155, miR-19a, miR-181b, and miR-24 enable monitoring of early breast cancer in serum
    • Sochor M, Basova P, Pesta M, et al. Oncogenic microRNAs: miR-155, miR-19a, miR-181b, and miR-24 enable monitoring of early breast cancer in serum. BMC Cancer 2014; 14: 448.
    • (2014) BMC Cancer , vol.14 , pp. 448
    • Sochor, M.1    Basova, P.2    Pesta, M.3
  • 201
    • 84906240084 scopus 로고    scopus 로고
    • Microparticles Mediate the Intercellular Regulation of microRNA-503 and Proline-Rich Tyrosine Kinase 2 to Alter the Migration and Invasion Capacity of Breast Cancer Cells
    • Gong J, Luk F, Jaiswal R, Bebawy M. Microparticles Mediate the Intercellular Regulation of microRNA-503 and Proline-Rich Tyrosine Kinase 2 to Alter the Migration and Invasion Capacity of Breast Cancer Cells. Front Oncol 2014; 4: 220.
    • (2014) Front Oncol , vol.4 , pp. 220
    • Gong, J.1    Luk, F.2    Jaiswal, R.3    Bebawy, M.4
  • 202
    • 37549024511 scopus 로고    scopus 로고
    • MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
    • Blenkiron C, Goldstein LD, Thorne NP, et al. MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol 2007; 8: R214.
    • (2007) Genome Biol , vol.8
    • Blenkiron, C.1    Goldstein, L.D.2    Thorne, N.P.3
  • 203
    • 69949189728 scopus 로고    scopus 로고
    • MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer
    • Lowery AJ, Miller N, Devaney A, et al. MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer. Breast Cancer Res 2009; 11: R27.
    • (2009) Breast Cancer Res , vol.11
    • Lowery, A.J.1    Miller, N.2    Devaney, A.3
  • 204
    • 51349103144 scopus 로고    scopus 로고
    • Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer
    • Foekens JA, Sieuwerts AM, Smid M, et al. Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer. Proc Natl Acad Sci U S A 2008; 105: 13021-13026.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13021-13026
    • Foekens, J.A.1    Sieuwerts, A.M.2    Smid, M.3
  • 205
    • 84896949069 scopus 로고    scopus 로고
    • microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers
    • Gasparini P, Cascione L, Fassan M, et al. microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers. Oncotarget 2014; 5: 1174-1184.
    • (2014) Oncotarget , vol.5 , pp. 1174-1184
    • Gasparini, P.1    Cascione, L.2    Fassan, M.3
  • 206
    • 79959637929 scopus 로고    scopus 로고
    • Global microRNA expression profiling identifies MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancer
    • Rothe F, Ignatiadis M, Chaboteaux C, et al. Global microRNA expression profiling identifies MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancer. PLoS One 2011; 6: e20980.
    • (2011) PLoS One , vol.6
    • Rothe, F.1    Ignatiadis, M.2    Chaboteaux, C.3
  • 207
    • 78149484489 scopus 로고    scopus 로고
    • The microRNA spectrum in 12 body fluids
    • Weber JA, Baxter DH, Zhang S, et al. The microRNA spectrum in 12 body fluids. Clin Chem 2010; 56: 1733-1741.
    • (2010) Clin Chem , vol.56 , pp. 1733-1741
    • Weber, J.A.1    Baxter, D.H.2    Zhang, S.3
  • 208
    • 78049339462 scopus 로고    scopus 로고
    • Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer
    • Roth C, Rack B, Muller V, et al. Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer. Breast Cancer Res 2010; 12: R90.
    • (2010) Breast Cancer Res , vol.12
    • Roth, C.1    Rack, B.2    Muller, V.3
  • 209
    • 77649138141 scopus 로고    scopus 로고
    • Circulating microRNAs as novel minimally invasive biomarkers for breast cancer
    • Heneghan HM, Miller N, Lowery AJ, et al. Circulating microRNAs as novel minimally invasive biomarkers for breast cancer. Ann Surg 2010; 251: 499-505.
    • (2010) Ann Surg , vol.251 , pp. 499-505
    • Heneghan, H.M.1    Miller, N.2    Lowery, A.J.3
  • 210
    • 80052679933 scopus 로고    scopus 로고
    • Next-generation sequencing of microRNAs for breast cancer detection
    • Wu Q, Lu Z, Li H, et al. Next-generation sequencing of microRNAs for breast cancer detection. J Biomed Biotechnol 2011; 2011: 597145.
    • (2011) J Biomed Biotechnol 2011
    • Wu, Q.1    Lu, Z.2    Li, H.3
  • 211
    • 84859604906 scopus 로고    scopus 로고
    • Serum microRNA profiling and breast cancer risk: the use of miR-484/191 as endogenous controls
    • Hu Z, Dong J, Wang LE, et al. Serum microRNA profiling and breast cancer risk: the use of miR-484/191 as endogenous controls. Carcinogenesis 2012; 33: 828-834.
    • (2012) Carcinogenesis , vol.33 , pp. 828-834
    • Hu, Z.1    Dong, J.2    Wang, L.E.3
  • 212
    • 84862109179 scopus 로고    scopus 로고
    • Global microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG study
    • Lyng MB, Laenkholm AV, Sokilde R, et al. Global microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG study. PLoS One 2012; 7: e36170.
    • (2012) PLoS One , vol.7
    • Lyng, M.B.1    Laenkholm, A.V.2    Sokilde, R.3
  • 213
    • 79954748720 scopus 로고    scopus 로고
    • MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer
    • Rodriguez-Gonzalez FG, Sieuwerts AM, Smid M, et al. MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer. Breast Cancer Res Treat 2011; 127: 43-51.
    • (2011) Breast Cancer Res Treat , vol.127 , pp. 43-51
    • Rodriguez-Gonzalez, F.G.1    Sieuwerts, A.M.2    Smid, M.3
  • 214
    • 70350528663 scopus 로고    scopus 로고
    • Widespread estrogen-dependent repression of micrornas involved in breast tumor cell growth
    • Maillot G, Lacroix-Triki M, Pierredon S, et al. Widespread estrogen-dependent repression of micrornas involved in breast tumor cell growth. Cancer Res 2009; 69: 8332-8340.
    • (2009) Cancer Res , vol.69 , pp. 8332-8340
    • Maillot, G.1    Lacroix-Triki, M.2    Pierredon, S.3
  • 215
    • 84861543054 scopus 로고    scopus 로고
    • Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration
    • Altman DG, McShane LM, Sauerbrei W, Taube SE. Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration. PLoS Med 2012; 9: e1001216.
    • (2012) PLoS Med , vol.9
    • Altman, D.G.1    McShane, L.M.2    Sauerbrei, W.3    Taube, S.E.4
  • 216
    • 34447306848 scopus 로고    scopus 로고
    • Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer
    • Valabrega G, Montemurro F, Aglietta M. Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer. Ann Oncol 2007; 18: 977-984.
    • (2007) Ann Oncol , vol.18 , pp. 977-984
    • Valabrega, G.1    Montemurro, F.2    Aglietta, M.3
  • 217
    • 84857582036 scopus 로고    scopus 로고
    • Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells
    • Ichikawa T, Sato F, Terasawa K, et al. Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells. PLoS One 2012; 7: e31422.
    • (2012) PLoS One , vol.7
    • Ichikawa, T.1    Sato, F.2    Terasawa, K.3
  • 218
    • 84883454157 scopus 로고    scopus 로고
    • The HER2-miR125a5p/miR125b loop in gastric and esophageal carcinogenesis
    • Fassan M, Pizzi M, Realdon S, et al. The HER2-miR125a5p/miR125b loop in gastric and esophageal carcinogenesis. Hum Pathol 2013; 44: 1804-1810.
    • (2013) Hum Pathol , vol.44 , pp. 1804-1810
    • Fassan, M.1    Pizzi, M.2    Realdon, S.3
  • 219
    • 33847738628 scopus 로고    scopus 로고
    • Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b
    • Scott GK, Goga A, Bhaumik D, et al. Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J Biol Chem 2007; 282: 1479-1486.
    • (2007) J Biol Chem , vol.282 , pp. 1479-1486
    • Scott, G.K.1    Goga, A.2    Bhaumik, D.3
  • 220
    • 60549104367 scopus 로고    scopus 로고
    • Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7
    • Dangi-Garimella S, Yun J, Eves EM, et al. Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J 2009; 28: 347-358.
    • (2009) EMBO J , vol.28 , pp. 347-358
    • Dangi-Garimella, S.1    Yun, J.2    Eves, E.M.3
  • 221
    • 84864072975 scopus 로고    scopus 로고
    • Modulation of MicroRNA-194 and cell migration by HER2-targeting trastuzumab in breast cancer
    • Le XF, Almeida MI, Mao W, et al. Modulation of MicroRNA-194 and cell migration by HER2-targeting trastuzumab in breast cancer. PLoS One 2012; 7: e41170.
    • (2012) PLoS One , vol.7
    • Le, X.F.1    Almeida, M.I.2    Mao, W.3
  • 222
    • 84860659806 scopus 로고    scopus 로고
    • Plasma microRNA 210 levels correlate with sensitivity to trastuzumab and tumor presence in breast cancer patients
    • Jung EJ, Santarpia L, Kim J, et al. Plasma microRNA 210 levels correlate with sensitivity to trastuzumab and tumor presence in breast cancer patients. Cancer 2012; 118: 2603-2614.
    • (2012) Cancer , vol.118 , pp. 2603-2614
    • Jung, E.J.1    Santarpia, L.2    Kim, J.3
  • 223
    • 84867353432 scopus 로고    scopus 로고
    • Serum microRNA-155 as a potential biomarker to track disease in breast cancer
    • Sun Y, Wang M, Lin G, et al. Serum microRNA-155 as a potential biomarker to track disease in breast cancer. PLoS One 2012; 7: e47003.
    • (2012) PLoS One , vol.7
    • Sun, Y.1    Wang, M.2    Lin, G.3
  • 224
    • 84906938995 scopus 로고    scopus 로고
    • Circulating cell-free cancer-testis MAGE-A RNA, BORIS RNA, let-7b and miR-202 in the blood of patients with breast cancer and benign breast diseases
    • Joosse SA, Muller V, Steinbach B, et al. Circulating cell-free cancer-testis MAGE-A RNA, BORIS RNA, let-7b and miR-202 in the blood of patients with breast cancer and benign breast diseases. Br J Cancer 2014; 111: 909-917.
    • (2014) Br J Cancer , vol.111 , pp. 909-917
    • Joosse, S.A.1    Muller, V.2    Steinbach, B.3
  • 225
    • 84928775471 scopus 로고    scopus 로고
    • A serum microRNA signature predicts tumor relapse and survival in triple-negative breast cancer patients
    • Kleivi Sahlberg K, Bottai G, Naume B, et al. A serum microRNA signature predicts tumor relapse and survival in triple-negative breast cancer patients. Clin Cancer Res 2015; 21: 1207-1214.
    • (2015) Clin Cancer Res , vol.21 , pp. 1207-1214
    • Kleivi Sahlberg, K.1    Bottai, G.2    Naume, B.3
  • 226
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 228
    • 33645135862 scopus 로고    scopus 로고
    • Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?
    • Weiler J, Hunziker J, Hall J. Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease? Gene Ther 2006; 13: 496-502.
    • (2006) Gene Ther , vol.13 , pp. 496-502
    • Weiler, J.1    Hunziker, J.2    Hall, J.3
  • 229
    • 33646027887 scopus 로고    scopus 로고
    • LNA-modified oligonucleotides mediate specific inhibition of microRNA function
    • Orom UA, Kauppinen S, Lund AH. LNA-modified oligonucleotides mediate specific inhibition of microRNA function. Gene 2006; 372: 137-141.
    • (2006) Gene , vol.372 , pp. 137-141
    • Orom, U.A.1    Kauppinen, S.2    Lund, A.H.3
  • 230
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with 'antagomirs'
    • Krutzfeldt J, Rajewsky N, Braich R, et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 2005; 438: 685-689.
    • (2005) Nature , vol.438 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 231
    • 84915745333 scopus 로고    scopus 로고
    • Chemistry, properties, and in vitro and in vivo applications of 2'-O-methoxyethyl-4'-thioRNA, a novel hybrid type of chemically modified RNA
    • Saito Y, Hashimoto Y, Arai M, et al. Chemistry, properties, and in vitro and in vivo applications of 2'-O-methoxyethyl-4'-thioRNA, a novel hybrid type of chemically modified RNA. Chembiochem 2014; 15: 2535-2540.
    • (2014) Chembiochem , vol.15 , pp. 2535-2540
    • Saito, Y.1    Hashimoto, Y.2    Arai, M.3
  • 232
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
    • Ebert MS, Neilson JR, Sharp PA. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods 2007; 4: 721-726.
    • (2007) Nat Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 233
    • 78149303249 scopus 로고    scopus 로고
    • MicroRNA sponges: progress and possibilities
    • Ebert MS, Sharp PA. MicroRNA sponges: progress and possibilities. RNA 2010; 16: 2043-2050.
    • (2010) RNA , vol.16 , pp. 2043-2050
    • Ebert, M.S.1    Sharp, P.A.2
  • 234
    • 84925487197 scopus 로고    scopus 로고
    • A lentiviral sponge for miRNA-21 diminishes aerobic glycolysis in bladder cancer T24 cells via the PTEN/PI3K/AKT/mTOR axis
    • Yang X, Cheng Y, Li P, et al. A lentiviral sponge for miRNA-21 diminishes aerobic glycolysis in bladder cancer T24 cells via the PTEN/PI3K/AKT/mTOR axis. Tumour Biol 2015; 36: 383-391.
    • (2015) Tumour Biol , vol.36 , pp. 383-391
    • Yang, X.1    Cheng, Y.2    Li, P.3
  • 235
    • 84891611546 scopus 로고    scopus 로고
    • miR-150 promotes human breast cancer growth and malignant behavior by targeting the pro-apoptotic purinergic P2X7 receptor
    • Huang S, Chen Y, Wu W, et al. miR-150 promotes human breast cancer growth and malignant behavior by targeting the pro-apoptotic purinergic P2X7 receptor. PLoS One 2013; 8: e80707.
    • (2013) PLoS One , vol.8
    • Huang, S.1    Chen, Y.2    Wu, W.3
  • 236
    • 33846887975 scopus 로고    scopus 로고
    • Naoe T, MicroRNAs 143 and 145 are possible common onco-microRNAs in human cancers
    • Akao Y, Nakagawa Y, Naoe T. MicroRNAs 143 and 145 are possible common onco-microRNAs in human cancers. Oncol Rep 2006; 16: 845-850.
    • (2006) Oncol Rep , vol.16 , pp. 845-850
    • Akao, Y.1    Nakagawa, Y.2
  • 237
    • 33646738061 scopus 로고    scopus 로고
    • Oligonucleotide-modified gold nanoparticles for intracellular gene regulation
    • Rosi NL, Giljohann DA, Thaxton CS, et al. Oligonucleotide-modified gold nanoparticles for intracellular gene regulation. Science 2006; 312: 1027-1030.
    • (2006) Science , vol.312 , pp. 1027-1030
    • Rosi, N.L.1    Giljohann, D.A.2    Thaxton, C.S.3
  • 238
    • 66449127352 scopus 로고    scopus 로고
    • Layer-by-layer assembled gold nanoparticles for siRNA delivery
    • Elbakry A, Zaky A, Liebl R, et al. Layer-by-layer assembled gold nanoparticles for siRNA delivery. Nano Lett 2009; 9: 2059-2064.
    • (2009) Nano Lett , vol.9 , pp. 2059-2064
    • Elbakry, A.1    Zaky, A.2    Liebl, R.3
  • 239
    • 66749180499 scopus 로고    scopus 로고
    • Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery
    • Lee JS, Green JJ, Love KT, et al. Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery. Nano Lett 2009; 9: 2402-2406.
    • (2009) Nano Lett , vol.9 , pp. 2402-2406
    • Lee, J.S.1    Green, J.J.2    Love, K.T.3
  • 240
    • 84916607343 scopus 로고    scopus 로고
    • Designing a gold nanoparticle-based nanocarrier for microRNA transfection into the prostate and breast cancer cells
    • Ekin A, Karatas OF, Culha M, Ozen M. Designing a gold nanoparticle-based nanocarrier for microRNA transfection into the prostate and breast cancer cells. J Gene Med 2014; 16: 331-335.
    • (2014) J Gene Med , vol.16 , pp. 331-335
    • Ekin, A.1    Karatas, O.F.2    Culha, M.3    Ozen, M.4
  • 241
    • 84879619753 scopus 로고    scopus 로고
    • Upregulation of miR-195 increases the sensitivity of breast cancer cells to Adriamycin treatment through inhibition of Raf-1
    • Yang G, Wu D, Zhu J, et al. Upregulation of miR-195 increases the sensitivity of breast cancer cells to Adriamycin treatment through inhibition of Raf-1. Oncol Rep 2013; 30: 877-889.
    • (2013) Oncol Rep , vol.30 , pp. 877-889
    • Yang, G.1    Wu, D.2    Zhu, J.3
  • 242
    • 79956313718 scopus 로고    scopus 로고
    • Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer
    • Gong C, Yao Y, Wang Y, et al. Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer. J Biol Chem 2011; 286: 19127-19137.
    • (2011) J Biol Chem , vol.286 , pp. 19127-19137
    • Gong, C.1    Yao, Y.2    Wang, Y.3
  • 243
    • 78650491562 scopus 로고    scopus 로고
    • Resistance may not be futile: microRNA biomarkers for chemoresistance and potential therapeutics
    • Allen KE, Weiss GJ. Resistance may not be futile: microRNA biomarkers for chemoresistance and potential therapeutics. Mol Cancer Ther 2010; 9: 3126-3136.
    • (2010) Mol Cancer Ther , vol.9 , pp. 3126-3136
    • Allen, K.E.1    Weiss, G.J.2
  • 244
    • 78651347241 scopus 로고    scopus 로고
    • Involvement of miR-21 in resistance to daunorubicin by regulating PTEN expression in the leukaemia K562 cell line
    • Bai H, Xu R, Cao Z, et al. Involvement of miR-21 in resistance to daunorubicin by regulating PTEN expression in the leukaemia K562 cell line. FEBS Lett 2011; 585: 402-408.
    • (2011) FEBS Lett , vol.585 , pp. 402-408
    • Bai, H.1    Xu, R.2    Cao, Z.3
  • 245
    • 84917710873 scopus 로고    scopus 로고
    • Targeting of miR34a-NOTCH1 axis reduced breast cancer stemness and chemoresistance
    • Park EY, Chang E, Lee EJ, et al. Targeting of miR34a-NOTCH1 axis reduced breast cancer stemness and chemoresistance. Cancer Res 2014; 74: 7573-7582.
    • (2014) Cancer Res , vol.74 , pp. 7573-7582
    • Park, E.Y.1    Chang, E.2    Lee, E.J.3
  • 246
    • 84883645909 scopus 로고    scopus 로고
    • A Bmi1-miRNAs cross-talk modulates chemotherapy response to 5-fluorouracil in breast cancer cells
    • Yin J, Zheng G, Jia X, et al. A Bmi1-miRNAs cross-talk modulates chemotherapy response to 5-fluorouracil in breast cancer cells. PLoS One 2013; 8: e73268.
    • (2013) PLoS One , vol.8
    • Yin, J.1    Zheng, G.2    Jia, X.3
  • 247
    • 84925282810 scopus 로고    scopus 로고
    • Blood-based multiple-microRNA assay displays a better diagnostic performance than single-microRNA assay in the diagnosis of breast tumor
    • Xin H, Li X, Yang B, et al. Blood-based multiple-microRNA assay displays a better diagnostic performance than single-microRNA assay in the diagnosis of breast tumor. Tumour Biol 2014; 35: 12635-12643.
    • (2014) Tumour Biol , vol.35 , pp. 12635-12643
    • Xin, H.1    Li, X.2    Yang, B.3


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