Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer

Journal of Biological Chemistry

Volumn 286, Issue 21, 2011, Pages 19127-19137

  Gong, Chang ^a   Yao, Yandan ^a   Wang, Ying ^a   Liu, Bodu ^a   Wu, Wei ^a   Chen, Jianing ^a   Su, Fengxi ^a   Yao, Herui ^a   Song, Erwei ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDES; BREAST CANCER; BREAST CANCER CELLS; BREAST CANCER XENOGRAFTS; BREAST TUMOR; CELL CYCLE; ECTOPIC EXPRESSIONS; EPIDERMAL GROWTH FACTOR RECEPTORS; GROWTH ARREST; GROWTH INHIBITION; IN-VIVO; LONG TERM EXPOSURE; OVER-EXPRESSION; PROLIFERATION INHIBITION; PROTEIN EXPRESSIONS; PTEN EXPRESSION; RESISTANT CELLS; THERAPEUTIC ACTIVITY; THERAPEUTIC POTENTIALS; TRASTUZUMAB; UP-REGULATION;

CELLS; DISEASES; GENE EXPRESSION; GENE THERAPY; OLIGONUCLEOTIDES; PATIENT TREATMENT; RESTORATION; TUMORS;

MONOCLONAL ANTIBODIES;

CARBOPLATIN; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MICRORNA 21; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TRASTUZUMAB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL VIABILITY; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LOADING DRUG DOSE; MOUSE; MULTIPLE CYCLE TREATMENT; NONHUMAN; ONCOGENE NEU; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE DRUG DOSE; TUMOR BIOPSY; TUMOR XENOGRAFT; UPREGULATION;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; DRUG RESISTANCE, NEOPLASM; FEMALE; G1 PHASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; MICRORNAS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PTEN PHOSPHOHYDROLASE; RECEPTOR, ERBB-2; RNA, NEOPLASM; S PHASE; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 79956313718     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.216887     Document Type: Article

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