메뉴 건너뛰기




Volumn 35, Issue 11, 2014, Pages 2567-2575

Overexpression of miR-146a in basal-like breast cancer cells confers enhanced tumorigenic potential in association with altered p53 status

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGOMIR; FAS ASSOCIATED DEATH DOMAIN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA 146A; PROTEIN P53; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; MICRORNA; MIRN146 MICRORNA, HUMAN; TP53 PROTEIN, HUMAN;

EID: 84965190935     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgu175     Document Type: Article
Times cited : (45)

References (50)
  • 1
    • 78651330430 scopus 로고    scopus 로고
    • COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
    • Forbes, S.A. et al. (2011) COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res., 39(Database issue), D945-D950.
    • (2011) Nucleic Acids Res , vol.39 , Issue.DATABASE ISSUE , pp. D945-D950
    • Forbes, S.A.1
  • 2
    • 0037221767 scopus 로고    scopus 로고
    • TP53 and breast cancer
    • Børresen-Dale, A.L. (2003) TP53 and breast cancer. Hum. Mutat., 21, 292-300.
    • (2003) Hum. Mutat , vol.21 , pp. 292-300
    • Børresen-Dale, A.L.1
  • 3
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Koboldt, D.C. et al. (2012) Comprehensive molecular portraits of human breast tumours. Nature, 490, 61-70.
    • (2012) Nature , vol.490 , pp. 61-70
    • Koboldt, D.C.1
  • 4
    • 33744960226 scopus 로고    scopus 로고
    • Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
    • Carey, L.A. et al. (2006) Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA, 295, 2492-2502.
    • (2006) JAMA , vol.295 , pp. 2492-2502
    • Carey, L.A.1
  • 5
    • 33846576225 scopus 로고    scopus 로고
    • Gene expression patterns associated with p53 status in breast cancer
    • Troester, M.A. et al. (2006) Gene expression patterns associated with p53 status in breast cancer. BMC Cancer, 6, 276.
    • (2006) BMC Cancer , vol.6 , pp. 276
    • Troester, M.A.1
  • 6
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sørlie, T. et al. (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl Acad. Sci. USA, 98, 10869-10874.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 10869-10874
    • Sørlie, T.1
  • 7
    • 34250760957 scopus 로고    scopus 로고
    • TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer
    • Langerød, A. et al. (2007) TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer. Breast Cancer Res., 9, R30.
    • (2007) Breast Cancer Res , vol.9 , pp. R30
    • Langerød, A.1
  • 8
    • 84872835399 scopus 로고    scopus 로고
    • Distinct tumor protein p53 mutants in breast cancer subgroups
    • Dumay, A. et al. (2013) Distinct tumor protein p53 mutants in breast cancer subgroups. Int. J. Cancer, 132, 1227-1231.
    • (2013) Int. J. Cancer , vol.132 , pp. 1227-1231
    • Dumay, A.1
  • 9
    • 33644772215 scopus 로고    scopus 로고
    • The clinical value of somatic TP53 gene mutations in 1, 794 patients with breast cancer
    • Olivier, M. et al. (2006) The clinical value of somatic TP53 gene mutations in 1, 794 patients with breast cancer. Clin. Cancer Res., 12, 1157-1167.
    • (2006) Clin. Cancer Res , vol.12 , pp. 1157-1167
    • Olivier, M.1
  • 10
    • 3042655539 scopus 로고    scopus 로고
    • Cell-type-specific responses to chemotherapeutics in breast cancer
    • Troester, M.A. et al. (2004) Cell-type-specific responses to chemotherapeutics in breast cancer. Cancer Res., 64, 4218-4226.
    • (2004) Cancer Res , vol.64 , pp. 4218-4226
    • Troester, M.A.1
  • 11
    • 67749143728 scopus 로고    scopus 로고
    • Modulation of microRNA processing by p53
    • Suzuki, H.I. et al. (2009) Modulation of microRNA processing by p53. Nature, 460, 529-533.
    • (2009) Nature , vol.460 , pp. 529-533
    • Suzuki, H.I.1
  • 12
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel, D.P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116, 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 13
    • 24344494340 scopus 로고    scopus 로고
    • How microRNAs control cell division, differentiation and death
    • Miska, E.A. (2005) How microRNAs control cell division, differentiation and death. Curr. Opin. Genet. Dev., 15, 563-568.
    • (2005) Curr. Opin. Genet. Dev , vol.15 , pp. 563-568
    • Miska, E.A.1
  • 14
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio, M.V. et al. (2005) MicroRNA gene expression deregulation in human breast cancer. Cancer Res., 65, 7065-7070.
    • (2005) Cancer Res , vol.65 , pp. 7065-7070
    • Iorio, M.V.1
  • 15
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang, T.C. et al. (2007) Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol. Cell, 26, 745-752.
    • (2007) Mol. Cell , vol.26 , pp. 745-752
    • Chang, T.C.1
  • 16
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • Corney, D.C. et al. (2007) MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res., 67, 8433-8438.
    • (2007) Cancer Res , vol.67 , pp. 8433-8438
    • Corney, D.C.1
  • 17
    • 62549148270 scopus 로고    scopus 로고
    • p53 represses c-Myc through induction of the tumor suppressor miR-145
    • Sachdeva, M. et al. (2009) p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc. Natl Acad. Sci. USA, 106, 3207-3212.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 3207-3212
    • Sachdeva, M.1
  • 18
    • 77950905821 scopus 로고    scopus 로고
    • P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
    • Yamakuchi, M. et al. (2010) P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proc. Natl Acad. Sci. USA, 107, 6334-6339.
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 6334-6339
    • Yamakuchi, M.1
  • 19
    • 57749116172 scopus 로고    scopus 로고
    • Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215
    • Georges, S.A. et al. (2008) Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215. Cancer Res., 68, 10105-10112.
    • (2008) Cancer Res , vol.68 , pp. 10105-10112
    • Georges, S.A.1
  • 20
    • 77953096272 scopus 로고    scopus 로고
    • Negative regulation of tumor suppressor p53 by micro-RNA miR-504
    • Hu, W. et al. (2010) Negative regulation of tumor suppressor p53 by micro-RNA miR-504. Mol. Cell, 38, 689-699.
    • (2010) Mol. Cell , vol.38 , pp. 689-699
    • Hu, W.1
  • 21
    • 64349101658 scopus 로고    scopus 로고
    • MicroRNA-125b is a novel negative regulator of p53
    • Le, M.T. et al. (2009) MicroRNA-125b is a novel negative regulator of p53. Genes Dev., 23, 862-876.
    • (2009) Genes Dev , vol.23 , pp. 862-876
    • Le, M.T.1
  • 22
    • 58149215802 scopus 로고    scopus 로고
    • miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42
    • Park, S.Y. et al. (2009) miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42. Nat. Struct. Mol. Biol., 16, 23-29.
    • (2009) Nat. Struct. Mol. Biol , vol.16 , pp. 23-29
    • Park, S.Y.1
  • 23
    • 51649115553 scopus 로고    scopus 로고
    • miR-34a repression of SIRT1 regulates apoptosis
    • Yamakuchi, M. et al. (2008) miR-34a repression of SIRT1 regulates apoptosis. Proc. Natl Acad. Sci. USA, 105, 13421-13426.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 13421-13426
    • Yamakuchi, M.1
  • 24
    • 67651007766 scopus 로고    scopus 로고
    • MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells
    • Fornari, F. et al. (2009) MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells. Cancer Res., 69, 5761-5767.
    • (2009) Cancer Res , vol.69 , pp. 5761-5767
    • Fornari, F.1
  • 25
    • 80052041448 scopus 로고    scopus 로고
    • Regulation of miR-146a by RelA/NFkB and p53 in STHdh(Q111)/Hdh(Q111) cells, a cell model of Huntington's disease
    • Ghose, J. et al. (2011) Regulation of miR-146a by RelA/NFkB and p53 in STHdh(Q111)/Hdh(Q111) cells, a cell model of Huntington's disease. PLoS One, 6, e23837.
    • (2011) PLoS One , vol.6
    • Ghose, J.1
  • 26
    • 37549024511 scopus 로고    scopus 로고
    • MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
    • Blenkiron, C. et al. (2007) MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol., 8, R214.
    • (2007) Genome Biol , vol.8 , pp. R214
    • Blenkiron, C.1
  • 27
    • 38949202308 scopus 로고    scopus 로고
    • Integrin-linked kinase: a hypoxia-induced antiapoptotic factor exploited by cancer cells
    • Abboud, E.R. et al. (2007) Integrin-linked kinase: a hypoxia-induced antiapoptotic factor exploited by cancer cells. Int. J. Oncol., 30, 113-122.
    • (2007) Int. J. Oncol , vol.30 , pp. 113-122
    • Abboud, E.R.1
  • 28
    • 1642553460 scopus 로고    scopus 로고
    • To be, or not to be: NF-kappaB is the answer-role of Rel/NF-kappaB in the regulation of apoptosis
    • Kucharczak, J. et al. (2003) To be, or not to be: NF-kappaB is the answer-role of Rel/NF-kappaB in the regulation of apoptosis. Oncogene, 22, 8961-8982.
    • (2003) Oncogene , vol.22 , pp. 8961-8982
    • Kucharczak, J.1
  • 29
    • 52149102044 scopus 로고    scopus 로고
    • Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells
    • Bhaumik, D. et al. (2008) Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells. Oncogene, 27, 5643-5647.
    • (2008) Oncogene , vol.27 , pp. 5643-5647
    • Bhaumik, D.1
  • 30
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov, K.D. et al. (2006) NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl Acad. Sci. USA, 103, 12481-12486.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1
  • 31
    • 79958742849 scopus 로고    scopus 로고
    • TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fasassociated death domain (FADD), and caspase-8
    • Ikner, A. et al. (2011) TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fasassociated death domain (FADD), and caspase-8. J. Biol. Chem., 286, 21546-21554.
    • (2011) J. Biol. Chem , vol.286 , pp. 21546-21554
    • Ikner, A.1
  • 32
    • 0028108985 scopus 로고
    • Database of p53 gene somatic mutations in human tumors and cell lines
    • Hollstein, M. et al. (1994) Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res., 22, 3551-3555.
    • (1994) Nucleic Acids Res , vol.22 , pp. 3551-3555
    • Hollstein, M.1
  • 33
    • 11344252796 scopus 로고    scopus 로고
    • Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations
    • Soussi, T. et al. (2005) Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations. Hum. Mutat., 25, 6-17.
    • (2005) Hum. Mutat , vol.25 , pp. 6-17
    • Soussi, T.1
  • 34
    • 33847063053 scopus 로고    scopus 로고
    • The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes
    • Carey, L.A. et al. (2007) The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin. Cancer Res., 13, 2329-2334.
    • (2007) Clin. Cancer Res , vol.13 , pp. 2329-2334
    • Carey, L.A.1
  • 35
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • Sorlie, T. et al. (2003) Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc. Natl Acad. Sci. USA, 100, 8418-8423.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 8418-8423
    • Sorlie, T.1
  • 36
    • 77953734977 scopus 로고    scopus 로고
    • Population-based estimate of the contribution of TP53 mutations to subgroups of early-onset breast cancer: Australian Breast Cancer Family Study
    • Mouchawar, J. et al. (2010) Population-based estimate of the contribution of TP53 mutations to subgroups of early-onset breast cancer: Australian Breast Cancer Family Study. Cancer Res., 70, 4795-4800.
    • (2010) Cancer Res , vol.70 , pp. 4795-4800
    • Mouchawar, J.1
  • 37
    • 84869171691 scopus 로고    scopus 로고
    • MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS
    • Ponomarev, E.D. et al. (2013) MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS. Glia, 61, 91-103.
    • (2013) Glia , vol.61 , pp. 91-103
    • Ponomarev, E.D.1
  • 38
    • 33645971047 scopus 로고    scopus 로고
    • Good cop, bad cop: the different faces of NF-kappaB
    • Perkins, N.D. et al. (2006) Good cop, bad cop: the different faces of NF-kappaB. Cell Death Differ., 13, 759-772.
    • (2006) Cell Death Differ , vol.13 , pp. 759-772
    • Perkins, N.D.1
  • 39
    • 84878113369 scopus 로고    scopus 로고
    • The shaping and functional consequences of the microRNA landscape in breast cancer
    • Dvinge, H. et al. (2013) The shaping and functional consequences of the microRNA landscape in breast cancer. Nature, 497, 378-382.
    • (2013) Nature , vol.497 , pp. 378-382
    • Dvinge, H.1
  • 40
    • 59849087052 scopus 로고    scopus 로고
    • MicroRNA-146a modulates human bronchial epithelial cell survival in response to the cytokine-induced apoptosis
    • Liu, X. et al. (2009) MicroRNA-146a modulates human bronchial epithelial cell survival in response to the cytokine-induced apoptosis. Biochem. Biophys. Res. Commun., 380, 177-182.
    • (2009) Biochem. Biophys. Res. Commun , vol.380 , pp. 177-182
    • Liu, X.1
  • 41
    • 53349120042 scopus 로고    scopus 로고
    • A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis
    • Shen, J. et al. (2008) A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis. Carcinogenesis, 29, 1963-1966.
    • (2008) Carcinogenesis , vol.29 , pp. 1963-1966
    • Shen, J.1
  • 42
    • 79955575393 scopus 로고    scopus 로고
    • Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers
    • Garcia, A.I. et al. (2011) Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. EMBO Mol. Med., 3, 279-290.
    • (2011) EMBO Mol. Med , vol.3 , pp. 279-290
    • Garcia, A.I.1
  • 43
    • 31544474577 scopus 로고    scopus 로고
    • BRCA1 mutation analysis of 41 human breast cancer cell lines reveals three new deleterious mutants
    • Elstrodt, F. et al. (2006) BRCA1 mutation analysis of 41 human breast cancer cell lines reveals three new deleterious mutants. Cancer Res., 66, 41-45.
    • (2006) Cancer Res , vol.66 , pp. 41-45
    • Elstrodt, F.1
  • 44
    • 84874456193 scopus 로고    scopus 로고
    • A systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells
    • Luo, D. et al. (2013) A systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells. J. Transl. Med., 11, 57.
    • (2013) J. Transl. Med , vol.11 , pp. 57
    • Luo, D.1
  • 45
    • 49749107841 scopus 로고    scopus 로고
    • Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth
    • Wang, X. et al. (2008) Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth. PLoS One, 3, e2557.
    • (2008) PLoS One , vol.3
    • Wang, X.1
  • 46
    • 77749233761 scopus 로고    scopus 로고
    • Nuclear factor-(kappa)B contributes to anaplastic thyroid carcinomas through up-regulation of miR-146a
    • Pacifico, F. et al. (2010) Nuclear factor-(kappa)B contributes to anaplastic thyroid carcinomas through up-regulation of miR-146a. J. Clin. Endocrinol. Metab., 95, 1421-1430.
    • (2010) J. Clin. Endocrinol. Metab , vol.95 , pp. 1421-1430
    • Pacifico, F.1
  • 47
    • 76749152907 scopus 로고    scopus 로고
    • miR-146a suppresses invasion of pancreatic cancer cells
    • Li, Y. et al. (2010) miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res., 70, 1486-1495.
    • (2010) Cancer Res , vol.70 , pp. 1486-1495
    • Li, Y.1
  • 48
    • 84878469848 scopus 로고    scopus 로고
    • MicroRNA-146a acts as a metastasis suppressor in gastric cancer by targeting WASF2
    • Yao, Q. et al. (2013) MicroRNA-146a acts as a metastasis suppressor in gastric cancer by targeting WASF2. Cancer Lett, 335, 219-224.
    • (2013) Cancer Lett , vol.335 , pp. 219-224
    • Yao, Q.1
  • 49
    • 80053015725 scopus 로고    scopus 로고
    • p53 isoforms: an intracellular microprocessor?
    • Khoury, M.P. et al. (2011) p53 isoforms: an intracellular microprocessor? Genes Cancer, 2, 453-465.
    • (2011) Genes Cancer , vol.2 , pp. 453-465
    • Khoury, M.P.1
  • 50
    • 0035751937 scopus 로고    scopus 로고
    • Assessing TP53 status in human tumours to evaluate clinical outcome
    • Soussi, T. et al. (2001) Assessing TP53 status in human tumours to evaluate clinical outcome. Nat. Rev. Cancer, 1, 233-240.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 233-240
    • Soussi, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.