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Volumn 231, Issue 1, 2016, Pages 3-14

Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELL; CANCER PATIENT; CANCER RADIOTHERAPY; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CHROMATIN; CHROMATIN STRUCTURE; COMPARATIVE STUDY; DNA DAMAGE; DNA DENATURATION; DNA END JOINING REPAIR; DNA REPLICATION; DNA TRANSCRIPTION; DOUBLE STRANDED DNA BREAK; EXCISION REPAIR; GENE OVEREXPRESSION; HETEROZYGOSITY LOSS; HUMAN; IONIZING RADIATION; LINEAR ENERGY TRANSFER; NONHUMAN; NUCLEOSOME; PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; RADIATION DOSE FRACTIONATION; RADIATION EXPOSURE; REGULATORY MECHANISM; REVIEW; ANIMAL; CELL CYCLE; DNA REPAIR; GENETICS; PHYSIOLOGY;

EID: 84942354037     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.25048     Document Type: Review
Times cited : (294)

References (161)
  • 1
    • 79956187736 scopus 로고    scopus 로고
    • Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation
    • Asaithamby A, Chen DJ. 2011. Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation. Mutat Res 711:87-99.
    • (2011) Mutat Res , vol.711 , pp. 87-99
    • Asaithamby, A.1    Chen, D.J.2
  • 4
    • 0032544035 scopus 로고    scopus 로고
    • DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone
    • Balasubramanian B, Pogozelski WK, Tullius TD. 1998. DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone. Proc Natl Acad Sci USA 95:9738-9743.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9738-9743
    • Balasubramanian, B.1    Pogozelski, W.K.2    Tullius, T.D.3
  • 5
    • 84875904745 scopus 로고    scopus 로고
    • The shape of the radiation dose response for DNA double-strand break induction and repair
    • Barnard S, Bouffler S, Rothkamm K. 2013. The shape of the radiation dose response for DNA double-strand break induction and repair. Genome Integr 4:1.
    • (2013) Genome Integr , vol.4 , pp. 1
    • Barnard, S.1    Bouffler, S.2    Rothkamm, K.3
  • 6
    • 0037437582 scopus 로고    scopus 로고
    • Modeling of ultrasoft X-ray induced DNA damage using structured higher order DNA targets
    • Bernhardt P, Friedland W, Jacob P, Paretzke H. 2003. Modeling of ultrasoft X-ray induced DNA damage using structured higher order DNA targets. Int J Mass Spectrometry 223:579-597.
    • (2003) Int J Mass Spectrometry , vol.223 , pp. 579-597
    • Bernhardt, P.1    Friedland, W.2    Jacob, P.3    Paretzke, H.4
  • 7
    • 0035178567 scopus 로고    scopus 로고
    • Base excision repair processing of radiation-induced clustered DNA lesions
    • Blaisdell JO, Harrison L, Wallace SS. 2001. Base excision repair processing of radiation-induced clustered DNA lesions. Radiat Prot Dosimetry 97:25-31.
    • (2001) Radiat Prot Dosimetry , vol.97 , pp. 25-31
    • Blaisdell, J.O.1    Harrison, L.2    Wallace, S.S.3
  • 8
    • 0035912756 scopus 로고    scopus 로고
    • Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
    • Blaisdell JO, Wallace SS. 2001. Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli. Proc Natl Acad Sci USA 98:7426-7430.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7426-7430
    • Blaisdell, J.O.1    Wallace, S.S.2
  • 9
    • 0029616307 scopus 로고
    • Ionizing radiation-induced DNA strand breakage and rejoining in specific genomic regions as determined by an alkaline unwinding/Southern blotting method
    • Bunch RT, Gewirtz DA, Povirk LF. 1995. Ionizing radiation-induced DNA strand breakage and rejoining in specific genomic regions as determined by an alkaline unwinding/Southern blotting method. Int J Radiat Biol 68:553-562.
    • (1995) Int J Radiat Biol , vol.68 , pp. 553-562
    • Bunch, R.T.1    Gewirtz, D.A.2    Povirk, L.F.3
  • 10
    • 84904480116 scopus 로고    scopus 로고
    • Nucleosomes suppress the formation of double-strand DNA breaks during attempted base excision repair of clustered oxidative damages
    • Cannan WJ, Tsang BP, Wallace SS, Pederson DS. 2014. Nucleosomes suppress the formation of double-strand DNA breaks during attempted base excision repair of clustered oxidative damages. J Biolog Chem 289:19881-19893.
    • (2014) J Biolog Chem , vol.289 , pp. 19881-19893
    • Cannan, W.J.1    Tsang, B.P.2    Wallace, S.S.3    Pederson, D.S.4
  • 12
    • 0034793185 scopus 로고    scopus 로고
    • Chromatin compaction and tumor cell radiosensitivity at 2 gray
    • Chapman JD, Stobbe CC, Matsumoto Y. 2001. Chromatin compaction and tumor cell radiosensitivity at 2 gray. Am J Clin Oncol 24:509-515.
    • (2001) Am J Clin Oncol , vol.24 , pp. 509-515
    • Chapman, J.D.1    Stobbe, C.C.2    Matsumoto, Y.3
  • 13
    • 84987081382 scopus 로고
    • Energy deposition mechanisms and biochemical aspects of DNA strand breaks by ionizing radiation
    • Chatterjee A, Holley WR. 1991. Energy deposition mechanisms and biochemical aspects of DNA strand breaks by ionizing radiation. Intl J Quantum Chem 39:709-727.
    • (1991) Intl J Quantum Chem , vol.39 , pp. 709-727
    • Chatterjee, A.1    Holley, W.R.2
  • 14
    • 13444257678 scopus 로고    scopus 로고
    • Bleomycins: Towards better therapeutics
    • Chen J, Stubbe J. 2005. Bleomycins: Towards better therapeutics. Nat Rev Cancer 5:102-112.
    • (2005) Nat Rev Cancer , vol.5 , pp. 102-112
    • Chen, J.1    Stubbe, J.2
  • 15
    • 0031861357 scopus 로고    scopus 로고
    • Radioprotection of cellular chromatin by the polyamines spermine and putrescine: Preferential action against formation of DNA-protein crosslinks
    • Chiu S, Oleinick NL. 1998. Radioprotection of cellular chromatin by the polyamines spermine and putrescine: Preferential action against formation of DNA-protein crosslinks. Radiat Res 149:543-549.
    • (1998) Radiat Res , vol.149 , pp. 543-549
    • Chiu, S.1    Oleinick, N.L.2
  • 16
    • 0020464945 scopus 로고
    • Hypersensitivity of DNA in transcriptionally active chromatin to ionizing radiation
    • Chiu SM, Oleinick NL, Friedman LR, Stambrook PJ. 1982. Hypersensitivity of DNA in transcriptionally active chromatin to ionizing radiation. Biochim Biophys Acta 699:15-21.
    • (1982) Biochim Biophys Acta , vol.699 , pp. 15-21
    • Chiu, S.M.1    Oleinick, N.L.2    Friedman, L.R.3    Stambrook, P.J.4
  • 17
    • 81955168032 scopus 로고    scopus 로고
    • The consequences of structural genomic alterations in humans: Genomic disorders, genomic instability and cancer
    • Colnaghi R, Carpenter G, Volker M, O'Driscoll M. 2011. The consequences of structural genomic alterations in humans: Genomic disorders, genomic instability and cancer. Semin Cell Dev Biol 22:875-885.
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 875-885
    • Colnaghi, R.1    Carpenter, G.2    Volker, M.3    O'Driscoll, M.4
  • 19
    • 0033957577 scopus 로고    scopus 로고
    • Comparison of biological effects of DNA damage induced by ionizing radiation and hydrogen peroxide in CHO cells
    • Dahm-Daphi J, Sass C, Alberti W. 2000. Comparison of biological effects of DNA damage induced by ionizing radiation and hydrogen peroxide in CHO cells. Intl J Radiat Biol 76:67-75.
    • (2000) Intl J Radiat Biol , vol.76 , pp. 67-75
    • Dahm-Daphi, J.1    Sass, C.2    Alberti, W.3
  • 20
    • 34250900982 scopus 로고    scopus 로고
    • Base-excision repair of oxidative DNA damage
    • David SS, O'Shea VL, Kundu S. 2007. Base-excision repair of oxidative DNA damage. Nature 447:941-950.
    • (2007) Nature , vol.447 , pp. 941-950
    • David, S.S.1    O'Shea, V.L.2    Kundu, S.3
  • 21
    • 2942523593 scopus 로고    scopus 로고
    • Endogenous DNA damage in humans: A review of quantitative data
    • De Bont R, van Larebeke N. 2004. Endogenous DNA damage in humans: A review of quantitative data. Mutagenesis 19:169-185.
    • (2004) Mutagenesis , vol.19 , pp. 169-185
    • De Bont, R.1    van Larebeke, N.2
  • 22
    • 84888594733 scopus 로고    scopus 로고
    • Initiation of meiotic recombination: How and where? Conservation and specificities among eukaryotes
    • de Massy B 2013. Initiation of meiotic recombination: How and where? Conservation and specificities among eukaryotes. Annu Rev Genet 47:563-599.
    • (2013) Annu Rev Genet , vol.47 , pp. 563-599
    • de Massy, B.1
  • 23
    • 77951977767 scopus 로고    scopus 로고
    • DNA interstrand cross-links induced by ionizing radiation: An unsung lesion
    • Dextraze ME, Gantchev T, Girouard S, Hunting D. 2010. DNA interstrand cross-links induced by ionizing radiation: An unsung lesion. Mutat Res 704:101-107.
    • (2010) Mutat Res , vol.704 , pp. 101-107
    • Dextraze, M.E.1    Gantchev, T.2    Girouard, S.3    Hunting, D.4
  • 24
    • 84902436603 scopus 로고    scopus 로고
    • Point/Counterpoint: Low-dose radiation is beneficial, not harmful
    • Doss M, Little MP, Orton CG. 2014. Point/Counterpoint: Low-dose radiation is beneficial, not harmful. Medical Phys 41:070601.
    • (2014) Medical Phys , vol.41 , pp. 070601
    • Doss, M.1    Little, M.P.2    Orton, C.G.3
  • 25
    • 0022230224 scopus 로고
    • DNA bending and its relation to nucleosome positioning
    • Drew HR, Travers AA. 1985. DNA bending and its relation to nucleosome positioning. J Mol Biol 186:773-790.
    • (1985) J Mol Biol , vol.186 , pp. 773-790
    • Drew, H.R.1    Travers, A.A.2
  • 27
    • 68349137541 scopus 로고    scopus 로고
    • Developmental genome rearrangements in ciliates: A natural genomic subtraction mediated by non-coding transcripts
    • Duharcourt S, Lepere G, Meyer E. 2009. Developmental genome rearrangements in ciliates: A natural genomic subtraction mediated by non-coding transcripts. Trends Genet 25:344-350.
    • (2009) Trends Genet , vol.25 , pp. 344-350
    • Duharcourt, S.1    Lepere, G.2    Meyer, E.3
  • 28
    • 79956197636 scopus 로고    scopus 로고
    • Delayed repair of radiation induced clustered DNA damage: Friend or foe?
    • Eccles LJ, O'Neill P, Lomax ME. 2011. Delayed repair of radiation induced clustered DNA damage: Friend or foe? Mutat Res 711:134-141.
    • (2011) Mutat Res , vol.711 , pp. 134-141
    • Eccles, L.J.1    O'Neill, P.2    Lomax, M.E.3
  • 29
    • 84978256394 scopus 로고
    • Über einen die Erzeugung und Verwandlung des Lichtes betreffenden heuristischen Gesichtspunkt
    • Einstein A 1905. Über einen die Erzeugung und Verwandlung des Lichtes betreffenden heuristischen Gesichtspunkt. Annalen der Physik 322:132-148.
    • (1905) Annalen der Physik , vol.322 , pp. 132-148
    • Einstein, A.1
  • 30
    • 55149112815 scopus 로고    scopus 로고
    • Chromatin structure influences the sensitivity of DNA to gamma-radiation
    • Falk M, Lukasova E, Kozubek S. 2008. Chromatin structure influences the sensitivity of DNA to gamma-radiation. Biochim Biophys Acta 1783:2398-2414.
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 2398-2414
    • Falk, M.1    Lukasova, E.2    Kozubek, S.3
  • 31
    • 77951976102 scopus 로고    scopus 로고
    • Higher-order chromatin structure in DSB induction, repair and misrepair
    • Falk M, Lukasova E, Kozubek S. 2010. Higher-order chromatin structure in DSB induction, repair and misrepair. Mutat Res 704:88-100.
    • (2010) Mutat Res , vol.704 , pp. 88-100
    • Falk, M.1    Lukasova, E.2    Kozubek, S.3
  • 32
    • 0000878535 scopus 로고
    • Solenoidal model for superstructure in chromatin
    • Finch JT, Klug A. 1976. Solenoidal model for superstructure in chromatin. Proc Natl Acad Sci USA 73:1897-1901.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 1897-1901
    • Finch, J.T.1    Klug, A.2
  • 33
    • 0032480023 scopus 로고    scopus 로고
    • Localization of chromosome breakpoints: Implication of the chromatin structure and nuclear architecture
    • Folle GA, Martinez-Lopez W, Boccardo E, Obe G. 1998. Localization of chromosome breakpoints: Implication of the chromatin structure and nuclear architecture. Mutat Res 404:17-26.
    • (1998) Mutat Res , vol.404 , pp. 17-26
    • Folle, G.A.1    Martinez-Lopez, W.2    Boccardo, E.3    Obe, G.4
  • 34
    • 84866728909 scopus 로고    scopus 로고
    • Chromothripsis and cancer: Causes and consequences of chromosome shattering
    • Forment JV, Kaidi A, Jackson SP. 2012. Chromothripsis and cancer: Causes and consequences of chromosome shattering. Nat Rev Cancer 12:663-670.
    • (2012) Nat Rev Cancer , vol.12 , pp. 663-670
    • Forment, J.V.1    Kaidi, A.2    Jackson, S.P.3
  • 35
    • 0025373259 scopus 로고
    • Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine
    • Fraga CG, Shigenaga MK, Park JW, Degan P, Ames BN. 1990. Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine. Proc Natl Acad Sci USA 87:4533-4537.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4533-4537
    • Fraga, C.G.1    Shigenaga, M.K.2    Park, J.W.3    Degan, P.4    Ames, B.N.5
  • 37
    • 61849132198 scopus 로고    scopus 로고
    • Single-strand annealing, conservative homologous recombination, nonhomologous DNA end joining, and the cell cycle-dependent repair of DNA double-strand breaks induced by sparsely or densely ionizing radiation
    • Frankenberg-Schwager M, Gebauer A, Koppe C, Wolf H, Pralle E, Frankenberg D. 2009. Single-strand annealing, conservative homologous recombination, nonhomologous DNA end joining, and the cell cycle-dependent repair of DNA double-strand breaks induced by sparsely or densely ionizing radiation. Radiat Res 171:265-273.
    • (2009) Radiat Res , vol.171 , pp. 265-273
    • Frankenberg-Schwager, M.1    Gebauer, A.2    Koppe, C.3    Wolf, H.4    Pralle, E.5    Frankenberg, D.6
  • 39
    • 77954997032 scopus 로고    scopus 로고
    • DNA damage signaling in response to double-strand breaks during mitosis
    • Giunta S, Belotserkovskaya R, Jackson SP. 2010. DNA damage signaling in response to double-strand breaks during mitosis. J Cell Biol 190:197-207.
    • (2010) J Cell Biol , vol.190 , pp. 197-207
    • Giunta, S.1    Belotserkovskaya, R.2    Jackson, S.P.3
  • 41
    • 0027180956 scopus 로고
    • Weiss Lecture. Effects of radiations of different qualities on cells: Molecular mechanisms of damage and repair
    • Goodhead DT, Thacker J, Cox R. 1993. Weiss Lecture. Effects of radiations of different qualities on cells: Molecular mechanisms of damage and repair. Int J Radiat Biol 63:543-556.
    • (1993) Int J Radiat Biol , vol.63 , pp. 543-556
    • Goodhead, D.T.1    Thacker, J.2    Cox, R.3
  • 42
    • 84861956987 scopus 로고    scopus 로고
    • Chromatin organization - the 30nm fiber
    • Grigoryev SA, Woodcock CL. 2012. Chromatin organization - the 30nm fiber. Exp Cell Res 318:1448-1455.
    • (2012) Exp Cell Res , vol.318 , pp. 1448-1455
    • Grigoryev, S.A.1    Woodcock, C.L.2
  • 43
    • 84860548726 scopus 로고    scopus 로고
    • Mating-type genes and MAT switching in Saccharomyces cerevisiae
    • Haber JE 2012. Mating-type genes and MAT switching in Saccharomyces cerevisiae. Genetics 191:33-64.
    • (2012) Genetics , vol.191 , pp. 33-64
    • Haber, J.E.1
  • 44
    • 84902081933 scopus 로고    scopus 로고
    • The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability
    • Hamperl S, Cimprich KA. 2014. The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability. DNA Repair 19:84-94.
    • (2014) DNA Repair , vol.19 , pp. 84-94
    • Hamperl, S.1    Cimprich, K.A.2
  • 45
    • 0032168167 scopus 로고    scopus 로고
    • Etoposide: Four decades of development of a topoisomerase II inhibitor
    • Hande KR 1998. Etoposide: Four decades of development of a topoisomerase II inhibitor. Eur J Cancer 34:1514-1521.
    • (1998) Eur J Cancer , vol.34 , pp. 1514-1521
    • Hande, K.R.1
  • 47
    • 38049112778 scopus 로고    scopus 로고
    • Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
    • Hegde ML, Hazra TK, Mitra S. 2008. Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res 18:27-47.
    • (2008) Cell Res , vol.18 , pp. 27-47
    • Hegde, M.L.1    Hazra, T.K.2    Mitra, S.3
  • 49
    • 0000540894 scopus 로고
    • Heterochromatin, chromocentren, chromomenen
    • Heitz E 1929. Heterochromatin, chromocentren, chromomenen. Ber Deutsch Bot Ges 47:274-284.
    • (1929) Ber Deutsch Bot Ges , vol.47 , pp. 274-284
    • Heitz, E.1
  • 54
    • 34447532525 scopus 로고    scopus 로고
    • Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals
    • Kim JA, Kruhlak M, Dotiwala F, Nussenzweig A, Haber JE. 2007. Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals. J Cell Biol 178:209-218.
    • (2007) J Cell Biol , vol.178 , pp. 209-218
    • Kim, J.A.1    Kruhlak, M.2    Dotiwala, F.3    Nussenzweig, A.4    Haber, J.E.5
  • 59
    • 0020583592 scopus 로고
    • Low angle x-ray diffraction studies of chromatin structure in vivo and in isolated nuclei and metaphase chromosomes
    • Langmore JP, Paulson JR. 1983. Low angle x-ray diffraction studies of chromatin structure in vivo and in isolated nuclei and metaphase chromosomes. J Cell Biol 96:1120-1131.
    • (1983) J Cell Biol , vol.96 , pp. 1120-1131
    • Langmore, J.P.1    Paulson, J.R.2
  • 60
    • 84894473902 scopus 로고    scopus 로고
    • Chromatin structure and radiation-induced DNA damage: From structural biology to radiobiology
    • Lavelle C, Foray N. 2014. Chromatin structure and radiation-induced DNA damage: From structural biology to radiobiology. Int J Biochem Cell Biol 49:84-97.
    • (2014) Int J Biochem Cell Biol , vol.49 , pp. 84-97
    • Lavelle, C.1    Foray, N.2
  • 61
    • 77953229115 scopus 로고    scopus 로고
    • The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
    • Lieber MR. 2010. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Ann Rev Biochem 79:181-211.
    • (2010) Ann Rev Biochem , vol.79 , pp. 181-211
    • Lieber, M.R.1
  • 62
    • 0015504248 scopus 로고
    • Rate of depurination of native deoxyribonucleic acid
    • Lindahl T, Nyberg B. 1972. Rate of depurination of native deoxyribonucleic acid. Biochemistry 11:3610-3618.
    • (1972) Biochemistry , vol.11 , pp. 3610-3618
    • Lindahl, T.1    Nyberg, B.2
  • 64
    • 0023433855 scopus 로고
    • Supercoiling of the DNA template during transcription
    • Liu LF, Wang JC. 1987. Supercoiling of the DNA template during transcription. Proc Natl Acad Sci USA 84:7024-7027.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7024-7027
    • Liu, L.F.1    Wang, J.C.2
  • 65
    • 0029860006 scopus 로고    scopus 로고
    • Non-random distribution of DNA double-strand breaks induced by particle irradiation
    • Lobrich M, Cooper PK, Rydberg B. 1996. Non-random distribution of DNA double-strand breaks induced by particle irradiation. Intl J Radiat Biol 70:493-503.
    • (1996) Intl J Radiat Biol , vol.70 , pp. 493-503
    • Lobrich, M.1    Cooper, P.K.2    Rydberg, B.3
  • 66
    • 84861604997 scopus 로고    scopus 로고
    • Beyond repair foci: DNA double-strand break repair in euchromatic and heterochromatic compartments analyzed by transmission electron microscopy
    • Lorat Y, Schanz S, Schuler N, Wennemuth G, Rube C, Rube CE. 2012. Beyond repair foci: DNA double-strand break repair in euchromatic and heterochromatic compartments analyzed by transmission electron microscopy. PloS ONE 7:e38165.
    • (2012) PloS ONE , vol.7 , pp. e38165
    • Lorat, Y.1    Schanz, S.2    Schuler, N.3    Wennemuth, G.4    Rube, C.5    Rube, C.E.6
  • 67
    • 1842411320 scopus 로고    scopus 로고
    • Crystal structure of the nucleosome core particle at 2.8 A resolution
    • Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ. 1997. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389:251-260.
    • (1997) Nature , vol.389 , pp. 251-260
    • Luger, K.1    Mader, A.W.2    Richmond, R.K.3    Sargent, D.F.4    Richmond, T.J.5
  • 68
    • 84863393824 scopus 로고    scopus 로고
    • Chromothripsis and human disease: Piecing together the shattering process
    • Maher CA, Wilson RK. 2012. Chromothripsis and human disease: Piecing together the shattering process. Cell 148:29-32.
    • (2012) Cell , vol.148 , pp. 29-32
    • Maher, C.A.1    Wilson, R.K.2
  • 69
    • 84887139861 scopus 로고    scopus 로고
    • Contribution of DNA unwrapping from histone octamers to the repair of oxidatively damaged DNA in nucleosomes
    • Maher RL, Prasad A, Rizvanova O, Wallace SS, Pederson DS. 2013. Contribution of DNA unwrapping from histone octamers to the repair of oxidatively damaged DNA in nucleosomes. DNA Repair 12:964-971.
    • (2013) DNA Repair , vol.12 , pp. 964-971
    • Maher, R.L.1    Prasad, A.2    Rizvanova, O.3    Wallace, S.S.4    Pederson, D.S.5
  • 70
    • 84870218426 scopus 로고    scopus 로고
    • Mutations arising during repair of chromosome breaks
    • Malkova A, Haber JE. 2012. Mutations arising during repair of chromosome breaks. Annu Rev Genet 46:455-473.
    • (2012) Annu Rev Genet , vol.46 , pp. 455-473
    • Malkova, A.1    Haber, J.E.2
  • 71
    • 84879887310 scopus 로고    scopus 로고
    • Break-induced replication: Functions and molecular mechanism
    • Malkova A, Ira G. 2013. Break-induced replication: Functions and molecular mechanism. Curr Opin Genet Dev 23:271-279.
    • (2013) Curr Opin Genet Dev , vol.23 , pp. 271-279
    • Malkova, A.1    Ira, G.2
  • 73
    • 84903757525 scopus 로고    scopus 로고
    • Sources of DNA double-strand breaks and models of recombinational DNA repair
    • Mehta A, Haber JE. 2014. Sources of DNA double-strand breaks and models of recombinational DNA repair. Cold Spring Harb Perspect Biol 6:a016428.
    • (2014) Cold Spring Harb Perspect Biol , vol.6 , pp. a016428
    • Mehta, A.1    Haber, J.E.2
  • 75
    • 0028521409 scopus 로고
    • Galactic cosmic ray composition and energy spectra
    • Mewaldt RA. 1994. Galactic cosmic ray composition and energy spectra. Adv Space Res 14:737-747.
    • (1994) Adv Space Res , vol.14 , pp. 737-747
    • Mewaldt, R.A.1
  • 76
    • 78650964769 scopus 로고    scopus 로고
    • Cancer genomes evolve by pulverizing single chromosomes
    • Meyerson M, Pellman D. 2011. Cancer genomes evolve by pulverizing single chromosomes. Cell 144:9-10.
    • (2011) Cell , vol.144 , pp. 9-10
    • Meyerson, M.1    Pellman, D.2
  • 77
    • 65549095526 scopus 로고    scopus 로고
    • Nucleases and helicases take center stage in homologous recombination
    • Mimitou EP, Symington LS. 2009. Nucleases and helicases take center stage in homologous recombination. Trends Biochem Sci 34:264-272.
    • (2009) Trends Biochem Sci , vol.34 , pp. 264-272
    • Mimitou, E.P.1    Symington, L.S.2
  • 78
    • 33947432388 scopus 로고    scopus 로고
    • Replication fork stalling at natural impediments
    • Mirkin EV, Mirkin SM. 2007. Replication fork stalling at natural impediments. Microbiol Mol Biol Rev 71:13-35.
    • (2007) Microbiol Mol Biol Rev , vol.71 , pp. 13-35
    • Mirkin, E.V.1    Mirkin, S.M.2
  • 81
    • 84942354308 scopus 로고    scopus 로고
    • APOD: 2006 August 14 - Cosmic Rays
    • NASA. 2006. APOD: 2006 August 14 - Cosmic Rays.
    • (2006)
  • 82
    • 84942354309 scopus 로고    scopus 로고
    • Who's Afraid of a Solar Flare?
    • NASA, Phillips T. 2005. Who's Afraid of a Solar Flare?
    • (2005)
    • Phillips, T.1
  • 83
    • 0014621384 scopus 로고
    • Heterochromatin and chromosome aberrations
    • Natarajan AT, Ahnstrom G. 1969. Heterochromatin and chromosome aberrations. Chromosoma 28:48-61.
    • (1969) Chromosoma , vol.28 , pp. 48-61
    • Natarajan, A.T.1    Ahnstrom, G.2
  • 84
    • 84868035470 scopus 로고    scopus 로고
    • Rules of engagement for base excision repair in chromatin
    • Odell ID, Wallace SS, Pederson DS. 2013. Rules of engagement for base excision repair in chromatin. J Cell Physiol 228:258-266.
    • (2013) J Cell Physiol , vol.228 , pp. 258-266
    • Odell, I.D.1    Wallace, S.S.2    Pederson, D.S.3
  • 85
    • 0015964401 scopus 로고
    • Spheroid chromatin units (v bodies)
    • Olins AL, Olins DE. 1974. Spheroid chromatin units (v bodies). Science 183:330-332.
    • (1974) Science , vol.183 , pp. 330-332
    • Olins, A.L.1    Olins, D.E.2
  • 86
    • 0018427513 scopus 로고
    • Stereo electron microscopy of the 25-nm chromatin fibers in isolated nuclei
    • Olins AL, Olins DE. 1979. Stereo electron microscopy of the 25-nm chromatin fibers in isolated nuclei. J Cell Biol 81:260-265.
    • (1979) J Cell Biol , vol.81 , pp. 260-265
    • Olins, A.L.1    Olins, D.E.2
  • 87
    • 0016687530 scopus 로고
    • Electron microscopic and biochemical evidence that chromatin structure is a repeating unit
    • Oudet P, Gross-Bellard M, Chambon P. 1975. Electron microscopic and biochemical evidence that chromatin structure is a repeating unit. Cell 4:281-300.
    • (1975) Cell , vol.4 , pp. 281-300
    • Oudet, P.1    Gross-Bellard, M.2    Chambon, P.3
  • 88
    • 0028130301 scopus 로고
    • Linker histones H1 and H5 prevent the mobility of positioned nucleosomes
    • Pennings S, Meersseman G, Bradbury EM. 1994. Linker histones H1 and H5 prevent the mobility of positioned nucleosomes. Proc Natl Acad Sci USA 91:10275-10279.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10275-10279
    • Pennings, S.1    Meersseman, G.2    Bradbury, E.M.3
  • 91
    • 0033855389 scopus 로고    scopus 로고
    • Mechanisms of DNA double-strand break repair and their potential to induce chromosomal aberrations
    • Pfeiffer P, Goedecke W, Obe G. 2000. Mechanisms of DNA double-strand break repair and their potential to induce chromosomal aberrations. Mutagenesis 15:289-302.
    • (2000) Mutagenesis , vol.15 , pp. 289-302
    • Pfeiffer, P.1    Goedecke, W.2    Obe, G.3
  • 92
    • 84942323458 scopus 로고    scopus 로고
    • The Mystery of High-Energy Cosmic Rays.
    • Pierre Auger Observatory. The Mystery of High-Energy Cosmic Rays.
  • 93
    • 21244488225 scopus 로고    scopus 로고
    • Evidence for complexity at the nanometer scale of radiation-induced DNA DSBs as a determinant of rejoining kinetics
    • Pinto M, Prise KM, Michael BD. 2005. Evidence for complexity at the nanometer scale of radiation-induced DNA DSBs as a determinant of rejoining kinetics. Radiat Res 164:73-85.
    • (2005) Radiat Res , vol.164 , pp. 73-85
    • Pinto, M.1    Prise, K.M.2    Michael, B.D.3
  • 94
    • 79952235291 scopus 로고    scopus 로고
    • Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications
    • Polo SE, Jackson SP. 2011. Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications. Genes Dev 25:409-433.
    • (2011) Genes Dev , vol.25 , pp. 409-433
    • Polo, S.E.1    Jackson, S.P.2
  • 95
    • 49549153065 scopus 로고
    • The relation between the unit thread of chromosomes and isolated nucleohistone
    • Pooley AS, Pardon JF, Richards BM. 1974. The relation between the unit thread of chromosomes and isolated nucleohistone. J Mol Biol 85:533-549.
    • (1974) J Mol Biol , vol.85 , pp. 533-549
    • Pooley, A.S.1    Pardon, J.F.2    Richards, B.M.3
  • 96
    • 0030591651 scopus 로고    scopus 로고
    • DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: Bleomycin, neocarzinostatin and other enediynes
    • Povirk LF 1996. DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: Bleomycin, neocarzinostatin and other enediynes. Mutat Res 355:71-89.
    • (1996) Mutat Res , vol.355 , pp. 71-89
    • Povirk, L.F.1
  • 97
    • 17144426028 scopus 로고    scopus 로고
    • Impairment of replication fork progression mediates RNA polII transcription-associated recombination
    • Prado F, Aguilera A. 2005. Impairment of replication fork progression mediates RNA polII transcription-associated recombination. EMBO J 24:1267-1276.
    • (2005) EMBO J , vol.24 , pp. 1267-1276
    • Prado, F.1    Aguilera, A.2
  • 98
    • 37549004382 scopus 로고    scopus 로고
    • Initiation of base excision repair of oxidative lesions in nucleosomes by the human, bifunctional DNA glycosylase NTH1
    • Prasad A, Wallace SS, Pederson DS. 2007. Initiation of base excision repair of oxidative lesions in nucleosomes by the human, bifunctional DNA glycosylase NTH1. Mol Cell Biol 27:8442-8453.
    • (2007) Mol Cell Biol , vol.27 , pp. 8442-8453
    • Prasad, A.1    Wallace, S.S.2    Pederson, D.S.3
  • 99
    • 0034753367 scopus 로고    scopus 로고
    • A review of studies of ionizing radiation-induced double-strand break clustering
    • Prise KM, Pinto M, Newman HC, Michael BD. 2001. A review of studies of ionizing radiation-induced double-strand break clustering. Radiat Res 156:572-576.
    • (2001) Radiat Res , vol.156 , pp. 572-576
    • Prise, K.M.1    Pinto, M.2    Newman, H.C.3    Michael, B.D.4
  • 100
    • 0021101211 scopus 로고
    • Periodicity of exonuclease III digestion of chromatin and the pitch of deoxyribonucleic acid on the nucleosome
    • Prunell A 1983. Periodicity of exonuclease III digestion of chromatin and the pitch of deoxyribonucleic acid on the nucleosome. Biochemistry 22:4887-4894.
    • (1983) Biochemistry , vol.22 , pp. 4887-4894
    • Prunell, A.1
  • 101
    • 0346103786 scopus 로고    scopus 로고
    • Chromatin organization contributes to non-randomly distributed double-strand breaks after exposure to high-LET radiation
    • Radulescu I, Elmroth K, Stenerlow B. 2004. Chromatin organization contributes to non-randomly distributed double-strand breaks after exposure to high-LET radiation. Radiat Res 161:1-8.
    • (2004) Radiat Res , vol.161 , pp. 1-8
    • Radulescu, I.1    Elmroth, K.2    Stenerlow, B.3
  • 102
  • 103
    • 0014885610 scopus 로고
    • Chromosome structure
    • Ris H, Kubai DF. 1970. Chromosome structure. Annu Rev Genet 4:263-294.
    • (1970) Annu Rev Genet , vol.4 , pp. 263-294
    • Ris, H.1    Kubai, D.F.2
  • 104
    • 62349120246 scopus 로고    scopus 로고
    • DNA repair in mammalian cells: Base excision repair: The long and short of it
    • Robertson AB, Klungland A, Rognes T, Leiros I. 2009. DNA repair in mammalian cells: Base excision repair: The long and short of it. Cell Mol Life Sci 66:981-993.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 981-993
    • Robertson, A.B.1    Klungland, A.2    Rognes, T.3    Leiros, I.4
  • 105
    • 84877696971 scopus 로고    scopus 로고
    • The structural location of DNA lesions in nucleosome core particles determines accessibility by base excision repair enzymes
    • Rodriguez Y, Smerdon MJ. 2013. The structural location of DNA lesions in nucleosome core particles determines accessibility by base excision repair enzymes. J Biol Chem 288:13863-13875.
    • (2013) J Biol Chem , vol.288 , pp. 13863-13875
    • Rodriguez, Y.1    Smerdon, M.J.2
  • 106
    • 0030023098 scopus 로고    scopus 로고
    • Clusters of DNA damage induced by ionizing radiation: Formation of short DNA fragments. II. Experimental detection
    • Rydberg B. 1996. Clusters of DNA damage induced by ionizing radiation: Formation of short DNA fragments. II. Experimental detection. Radiat Res 145:200-209.
    • (1996) Radiat Res , vol.145 , pp. 200-209
    • Rydberg, B.1
  • 107
    • 0035179431 scopus 로고    scopus 로고
    • Radiation-induced DNA damage and chromatin structure
    • Rydberg B. 2001. Radiation-induced DNA damage and chromatin structure. Acta Oncol 40:682-685.
    • (2001) Acta Oncol , vol.40 , pp. 682-685
    • Rydberg, B.1
  • 108
    • 0032553448 scopus 로고    scopus 로고
    • Chromatin conformation in living cells: Support for a zig-zag model of the 30nm chromatin fiber
    • Rydberg B, Holley WR, Mian IS, Chatterjee A. 1998. Chromatin conformation in living cells: Support for a zig-zag model of the 30nm chromatin fiber. J Mol Biol 284:71-84.
    • (1998) J Mol Biol , vol.284 , pp. 71-84
    • Rydberg, B.1    Holley, W.R.2    Mian, I.S.3    Chatterjee, A.4
  • 109
    • 79956225907 scopus 로고    scopus 로고
    • Clustered DNA lesion repair in eukaryotes: Relevance to mutagenesis and cell survival
    • Sage E, Harrison L. 2011. Clustered DNA lesion repair in eukaryotes: Relevance to mutagenesis and cell survival. Mutat Res 711:123-133.
    • (2011) Mutat Res , vol.711 , pp. 123-133
    • Sage, E.1    Harrison, L.2
  • 110
    • 50649100744 scopus 로고    scopus 로고
    • Mechanism of eukaryotic homologous recombination
    • San Filippo J, Sung P, Klein H. 2008. Mechanism of eukaryotic homologous recombination. Ann Rev Biochem 77:229-257.
    • (2008) Ann Rev Biochem , vol.77 , pp. 229-257
    • San Filippo, J.1    Sung, P.2    Klein, H.3
  • 111
    • 0023001414 scopus 로고
    • Sequence periodicities in chicken nucleosome core DNA
    • Satchwell SC, Drew HR, Travers AA. 1986. Sequence periodicities in chicken nucleosome core DNA. J Mol Biol 191:659-675.
    • (1986) J Mol Biol , vol.191 , pp. 659-675
    • Satchwell, S.C.1    Drew, H.R.2    Travers, A.A.3
  • 112
    • 0001250708 scopus 로고
    • Chromosome Aberrations Induced by X-Rays
    • Sax K. 1938. Chromosome Aberrations Induced by X-Rays. Genetics 23:494-516.
    • (1938) Genetics , vol.23 , pp. 494-516
    • Sax, K.1
  • 113
    • 2442448170 scopus 로고    scopus 로고
    • A fast Monte Carlo algorithm to simulate the spectrum of DNA damages formed by ionizing radiation
    • Semenenko VA, Stewart RD. 2004. A fast Monte Carlo algorithm to simulate the spectrum of DNA damages formed by ionizing radiation. Radiat Res 161:451-457.
    • (2004) Radiat Res , vol.161 , pp. 451-457
    • Semenenko, V.A.1    Stewart, R.D.2
  • 114
    • 0028174439 scopus 로고
    • Distribution of X-ray-induced G2 chromatid damage among Chinese hamster chromosomes: Influence of chromatin conformation
    • Slijepcevic P, Natarajan AT. 1994. Distribution of X-ray-induced G2 chromatid damage among Chinese hamster chromosomes: Influence of chromatin conformation. Mutat Res 323:113-119.
    • (1994) Mutat Res , vol.323 , pp. 113-119
    • Slijepcevic, P.1    Natarajan, A.T.2
  • 115
    • 34547499407 scopus 로고    scopus 로고
    • Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases
    • Smolka MB, Albuquerque CP, Chen SH, Zhou H. 2007. Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases. Proc Natl Acad Sci USA 104:10364-10369.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 10364-10369
    • Smolka, M.B.1    Albuquerque, C.P.2    Chen, S.H.3    Zhou, H.4
  • 119
    • 84871702380 scopus 로고    scopus 로고
    • Gamma-H2AX foci in cells exposed to a mixed beam of X-rays and alpha particles
    • Staaf E, Brehwens K, Haghdoost S, Czub J, Wojcik A. 2012. Gamma-H2AX foci in cells exposed to a mixed beam of X-rays and alpha particles. Genome Integr 3:8.
    • (2012) Genome Integr , vol.3 , pp. 8
    • Staaf, E.1    Brehwens, K.2    Haghdoost, S.3    Czub, J.4    Wojcik, A.5
  • 120
    • 79955632686 scopus 로고    scopus 로고
    • Complex regulation and function of activation-induced cytidine deaminase
    • Stavnezer J 2011. Complex regulation and function of activation-induced cytidine deaminase. Trends Immunol 32:194-201.
    • (2011) Trends Immunol , vol.32 , pp. 194-201
    • Stavnezer, J.1
  • 121
    • 18744398382 scopus 로고    scopus 로고
    • The radiation hypersensitivity of cells at mitosis
    • Stobbe CC, Park SJ, Chapman JD. 2002. The radiation hypersensitivity of cells at mitosis. Intl J Radiat Biol 78:1149-1157.
    • (2002) Intl J Radiat Biol , vol.78 , pp. 1149-1157
    • Stobbe, C.C.1    Park, S.J.2    Chapman, J.D.3
  • 122
    • 84867516583 scopus 로고    scopus 로고
    • The effect of photon energy on intensity-modulated radiation therapy (IMRT) plans for prostate cancer
    • Sung W, Park JM, Choi CH, Ha SW, Ye SJ. 2012. The effect of photon energy on intensity-modulated radiation therapy (IMRT) plans for prostate cancer. Radiat Oncol J 30:27-35.
    • (2012) Radiat Oncol J , vol.30 , pp. 27-35
    • Sung, W.1    Park, J.M.2    Choi, C.H.3    Ha, S.W.4    Ye, S.J.5
  • 123
    • 0034636776 scopus 로고    scopus 로고
    • Clustered damages and total lesions induced in DNA by ionizing radiation: Oxidized bases and strand breaks
    • Sutherland BM, Bennett PV, Sidorkina O, Laval J. 2000a. Clustered damages and total lesions induced in DNA by ionizing radiation: Oxidized bases and strand breaks. Biochemistry 39:8026-8031.
    • (2000) Biochemistry , vol.39 , pp. 8026-8031
    • Sutherland, B.M.1    Bennett, P.V.2    Sidorkina, O.3    Laval, J.4
  • 124
    • 0034602643 scopus 로고    scopus 로고
    • Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation
    • Sutherland BM, Bennett PV, Sidorkina O, Laval J. 2000b. Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation. Procee Natl Acad Sci USA 97:103-108.
    • (2000) Procee Natl Acad Sci USA , vol.97 , pp. 103-108
    • Sutherland, B.M.1    Bennett, P.V.2    Sidorkina, O.3    Laval, J.4
  • 125
    • 0345016976 scopus 로고    scopus 로고
    • Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis
    • Sutherland BM, Georgakilas AG, Bennett PV, Laval J, Sutherland JC. 2003. Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis. Mutat Res 531:93-107.
    • (2003) Mutat Res , vol.531 , pp. 93-107
    • Sutherland, B.M.1    Georgakilas, A.G.2    Bennett, P.V.3    Laval, J.4    Sutherland, J.C.5
  • 126
    • 0028783460 scopus 로고
    • Neutron and gamma-radiation sensitivity of plasmid DNA of varying superhelical density
    • Swenberg CE, Speicher JM. 1995. Neutron and gamma-radiation sensitivity of plasmid DNA of varying superhelical density. Radiat Res 144:301-309.
    • (1995) Radiat Res , vol.144 , pp. 301-309
    • Swenberg, C.E.1    Speicher, J.M.2
  • 129
    • 79551661538 scopus 로고    scopus 로고
    • Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae
    • Takahashi T, Burguiere-Slezak G, Van der Kemp PA, Boiteux S. 2011. Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 108:692-697.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 692-697
    • Takahashi, T.1    Burguiere-Slezak, G.2    Van der Kemp, P.A.3    Boiteux, S.4
  • 132
    • 84865620494 scopus 로고    scopus 로고
    • Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography
    • Thompson LH. 2012. Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography. Mutat Res 751:158-246.
    • (2012) Mutat Res , vol.751 , pp. 158-246
    • Thompson, L.H.1
  • 133
    • 0002613038 scopus 로고
    • Handbook of the biology of aging/ editors, CE Finch, EL Schneider, with the assistance of associate editors, RC Adelman, GM Martin, EJ Masoro.
    • Tice R, Setlow R. 1985. DNA repair and replication in aging organisms and cells. Handbook of the biology of aging/ editors, CE Finch, EL Schneider, with the assistance of associate editors, RC Adelman, GM Martin, EJ Masoro.
    • (1985) DNA repair and replication in aging organisms and cells
    • Tice, R.1    Setlow, R.2
  • 135
    • 33847106524 scopus 로고    scopus 로고
    • Higher-order structures of chromatin: The elusive 30nm fiber
    • Tremethick DJ 2007. Higher-order structures of chromatin: The elusive 30nm fiber. Cell 128:651-654.
    • (2007) Cell , vol.128 , pp. 651-654
    • Tremethick, D.J.1
  • 136
    • 84877321963 scopus 로고    scopus 로고
    • Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells
    • Truong LN, Li Y, Shi LZ, Hwang PY, He J, Wang H, Razavian N, Berns MW, Wu X. 2013. Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells. Proc Natl Acad Sci USA 110:7720-7725.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 7720-7725
    • Truong, L.N.1    Li, Y.2    Shi, L.Z.3    Hwang, P.Y.4    He, J.5    Wang, H.6    Razavian, N.7    Berns, M.W.8    Wu, X.9
  • 137
    • 79952120598 scopus 로고    scopus 로고
    • Cancer: When catastrophe strikes a cell
    • Tubio JM, Estivill X. 2011. Cancer: When catastrophe strikes a cell. Nature 470:476-477.
    • (2011) Nature , vol.470 , pp. 476-477
    • Tubio, J.M.1    Estivill, X.2
  • 138
    • 84905454832 scopus 로고    scopus 로고
    • Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age
    • Vaidya A, Mao Z, Tian X, Spencer B, Seluanov A, Gorbunova V. 2014. Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age. PLoS Genet 10:e1004511.
    • (2014) PLoS Genet , vol.10 , pp. e1004511
    • Vaidya, A.1    Mao, Z.2    Tian, X.3    Spencer, B.4    Seluanov, A.5    Gorbunova, V.6
  • 139
    • 0037079669 scopus 로고    scopus 로고
    • Polyamine-nucleic acid interactions and the effects on structure in oriented DNA fibers
    • van Dam L, Korolev N, Nordenskiold L. 2002. Polyamine-nucleic acid interactions and the effects on structure in oriented DNA fibers. Nucleic Acids Res 30:419-428.
    • (2002) Nucleic Acids Res , vol.30 , pp. 419-428
    • van Dam, L.1    Korolev, N.2    Nordenskiold, L.3
  • 140
    • 35648930403 scopus 로고    scopus 로고
    • Chromatin fiber structure: Where is the problem now?
    • van Holde K, Zlatanova J. 2007. Chromatin fiber structure: Where is the problem now? Semin Cell Dev Biol 18:651-658.
    • (2007) Semin Cell Dev Biol , vol.18 , pp. 651-658
    • van Holde, K.1    Zlatanova, J.2
  • 142
    • 0141854009 scopus 로고    scopus 로고
    • The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes
    • Versteeg R, van Schaik BD, van Batenburg MF, Roos M, Monajemi R, Caron H, Bussemaker HJ, van Kampen AH. 2003. The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes. Genome Res 13:1998-2004.
    • (2003) Genome Res , vol.13 , pp. 1998-2004
    • Versteeg, R.1    van Schaik, B.D.2    van Batenburg, M.F.3    Roos, M.4    Monajemi, R.5    Caron, H.6    Bussemaker, H.J.7    van Kampen, A.H.8
  • 143
    • 0242300088 scopus 로고    scopus 로고
    • Endogenous DNA double-strand breaks: Production, fidelity of repair, and induction of cancer
    • Vilenchik MM, Knudson AG. 2003. Endogenous DNA double-strand breaks: Production, fidelity of repair, and induction of cancer. Proc Natl Acad Sci USA 100:12871-12876.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12871-12876
    • Vilenchik, M.M.1    Knudson, A.G.2
  • 144
    • 84879062475 scopus 로고    scopus 로고
    • The homologous recombination machinery modulates the formation of RNA-DNA hybrids and associated chromosome instability
    • Wahba L, Gore SK, Koshland D. 2013. The homologous recombination machinery modulates the formation of RNA-DNA hybrids and associated chromosome instability. Elife 2:e00505.
    • (2013) Elife , vol.2 , pp. e00505
    • Wahba, L.1    Gore, S.K.2    Koshland, D.3
  • 145
    • 0035833552 scopus 로고    scopus 로고
    • Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
    • Walker JR, Corpina RA, Goldberg J. 2001. Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature 412:607-614.
    • (2001) Nature , vol.412 , pp. 607-614
    • Walker, J.R.1    Corpina, R.A.2    Goldberg, J.3
  • 146
    • 84902073074 scopus 로고    scopus 로고
    • Base excision repair: A critical player in many games
    • Wallace SS. 2014. Base excision repair: A critical player in many games. DNA Repair 19:14-26.
    • (2014) DNA Repair , vol.19 , pp. 14-26
    • Wallace, S.S.1
  • 147
    • 0024195429 scopus 로고
    • DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation, and reparability
    • Ward J. 1988. DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation, and reparability. Prog Nucleic Acid Res Mol Biol 35:95-125.
    • (1988) Prog Nucleic Acid Res Mol Biol , vol.35 , pp. 95-125
    • Ward, J.1
  • 148
    • 0033013759 scopus 로고    scopus 로고
    • Radioprotection of human cell nuclear DNA by polyamines: Radiosensitivity of chromatin is influenced by tightly bound spermine
    • Warters RL, Newton GL, Olive PL, Fahey RC. 1999. Radioprotection of human cell nuclear DNA by polyamines: Radiosensitivity of chromatin is influenced by tightly bound spermine. Radiat Res 151:354-362.
    • (1999) Radiat Res , vol.151 , pp. 354-362
    • Warters, R.L.1    Newton, G.L.2    Olive, P.L.3    Fahey, R.C.4
  • 149
    • 0025924082 scopus 로고
    • 32P-postlabeling detection of radiation-induced DNA damage: Identification and estimation of thymine glycols and phosphoglycolate termini
    • Weinfeld M, Soderlind KJ. 1991. 32P-postlabeling detection of radiation-induced DNA damage: Identification and estimation of thymine glycols and phosphoglycolate termini. Biochemistry 30:1091-1097.
    • (1991) Biochemistry , vol.30 , pp. 1091-1097
    • Weinfeld, M.1    Soderlind, K.J.2
  • 150
    • 33645823661 scopus 로고    scopus 로고
    • Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex
    • Wellinger RE, Prado F, Aguilera A. 2006. Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex. Mol Cell Biol 26:3327-3334.
    • (2006) Mol Cell Biol , vol.26 , pp. 3327-3334
    • Wellinger, R.E.1    Prado, F.2    Aguilera, A.3
  • 151
    • 0017251130 scopus 로고
    • Structural repeating units in chromatin. I. Evidence for their general occurrence
    • Woodcock CL, Safer JP, Stanchfield JE. 1976. Structural repeating units in chromatin. I. Evidence for their general occurrence. Exp Cell Res 97:101-110.
    • (1976) Exp Cell Res , vol.97 , pp. 101-110
    • Woodcock, C.L.1    Safer, J.P.2    Stanchfield, J.E.3
  • 152
    • 0017688585 scopus 로고
    • Higher order coiling of DNA in chromatin
    • Worcel A, Benyajati C. 1977. Higher order coiling of DNA in chromatin. Cell 12:83-100.
    • (1977) Cell , vol.12 , pp. 83-100
    • Worcel, A.1    Benyajati, C.2
  • 153
    • 77549087694 scopus 로고    scopus 로고
    • WHO Handbook on Indoor Radon: A Public Health Perspective. Geneva.
    • World Health Organization. 2009. WHO Handbook on Indoor Radon: A Public Health Perspective. WHO Handbook on Indoor Radon: A Public Health Perspective. Geneva.
    • (2009) WHO Handbook on Indoor Radon: A Public Health Perspective
  • 154
    • 0033598810 scopus 로고    scopus 로고
    • Modulation of enediyne-induced DNA damage by chromatin structures in transcriptionally active genes
    • Wu J, Xu J, Dedon PC. 1999. Modulation of enediyne-induced DNA damage by chromatin structures in transcriptionally active genes. Biochemistry 38:15641-15646.
    • (1999) Biochemistry , vol.38 , pp. 15641-15646
    • Wu, J.1    Xu, J.2    Dedon, P.C.3
  • 156
    • 27744476436 scopus 로고    scopus 로고
    • Estimation of yields of OH radicals in water irradiated by ionizing radiation
    • Yamaguchi H, Uchihori Y, Yasuda N, Takada M, Kitamura H. 2005. Estimation of yields of OH radicals in water irradiated by ionizing radiation. J Radiat Res 46:333-341.
    • (2005) J Radiat Res , vol.46 , pp. 333-341
    • Yamaguchi, H.1    Uchihori, Y.2    Yasuda, N.3    Takada, M.4    Kitamura, H.5
  • 157
    • 29244473835 scopus 로고    scopus 로고
    • Base excision repair by hNTH1 and hOG G1: A two edged sword in the processing of DNA damage in gamma-irradiated human cells
    • Yang N, Chaudhry MA, Wallace SS. 2006. Base excision repair by hNTH1 and hOG G1: A two edged sword in the processing of DNA damage in gamma-irradiated human cells. DNA Repair 5:43-51.
    • (2006) DNA Repair , vol.5 , pp. 43-51
    • Yang, N.1    Chaudhry, M.A.2    Wallace, S.S.3
  • 158
    • 4444325894 scopus 로고    scopus 로고
    • Attempted base excision repair of ionizing radiation damage in human lymphoblastoid cells produces lethal and mutagenic double strand breaks
    • Yang N, Galick H, Wallace SS. 2004. Attempted base excision repair of ionizing radiation damage in human lymphoblastoid cells produces lethal and mutagenic double strand breaks. DNA Repair 3:1323-1334.
    • (2004) DNA Repair , vol.3 , pp. 1323-1334
    • Yang, N.1    Galick, H.2    Wallace, S.S.3
  • 160
    • 67349246802 scopus 로고    scopus 로고
    • CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
    • Yun MH, Hiom K. 2009. CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. Nature 459:460-463.
    • (2009) Nature , vol.459 , pp. 460-463
    • Yun, M.H.1    Hiom, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.