-
1
-
-
0023555502
-
Radiation hazards on space missions
-
Letaw J.R., Silberberg R., Tsao C.H. Radiation hazards on space missions. Nature 1987, 330:709-710.
-
(1987)
Nature
, vol.330
, pp. 709-710
-
-
Letaw, J.R.1
Silberberg, R.2
Tsao, C.H.3
-
2
-
-
0035667390
-
Chromosome aberrations in the blood lymphocytes of astronauts after space flight
-
George K., Durante M., Wu H., Willingham V., Badhwar G., Cucinotta F.A. Chromosome aberrations in the blood lymphocytes of astronauts after space flight. Radiat. Res. 2001, 156:731-738.
-
(2001)
Radiat. Res.
, vol.156
, pp. 731-738
-
-
George, K.1
Durante, M.2
Wu, H.3
Willingham, V.4
Badhwar, G.5
Cucinotta, F.A.6
-
3
-
-
77951298967
-
New radiobiological, radiation risk and radiation protection paradigms
-
Goodhead D.T. New radiobiological, radiation risk and radiation protection paradigms. Mutat. Res. 2010, 687:13-16.
-
(2010)
Mutat. Res.
, vol.687
, pp. 13-16
-
-
Goodhead, D.T.1
-
4
-
-
44349143334
-
Heavy ion carcinogenesis and human space exploration
-
Durante M., Cucinotta F.A. Heavy ion carcinogenesis and human space exploration. Nat. Rev. Cancer 2008, 8:465-472.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 465-472
-
-
Durante, M.1
Cucinotta, F.A.2
-
5
-
-
0024857545
-
Galactic cosmic rays and cell-hit frequencies outside the magnetosphere
-
Curtis S.B., Letaw J.R. Galactic cosmic rays and cell-hit frequencies outside the magnetosphere. Adv. Space Res. 1989, 9:293-298.
-
(1989)
Adv. Space Res.
, vol.9
, pp. 293-298
-
-
Curtis, S.B.1
Letaw, J.R.2
-
6
-
-
0023750512
-
Radiation protection guidelines for space missions
-
Fry R.J., Nachtwey D.S. Radiation protection guidelines for space missions. Health Phys. 1988, 55:159-164.
-
(1988)
Health Phys.
, vol.55
, pp. 159-164
-
-
Fry, R.J.1
Nachtwey, D.S.2
-
7
-
-
0242267007
-
The increased biological effectiveness of heavy charged particles: from radiobiology to treatment planning
-
Kramer M., Weyrather W.K., Scholz M. The increased biological effectiveness of heavy charged particles: from radiobiology to treatment planning. Technol. Cancer Res. Treat. 2003, 2:427-436.
-
(2003)
Technol. Cancer Res. Treat.
, vol.2
, pp. 427-436
-
-
Kramer, M.1
Weyrather, W.K.2
Scholz, M.3
-
8
-
-
19444362723
-
Dose-dependent misrejoining of radiation-induced DNA double-strand breaks in human fibroblasts: experimental and theoretical study for high- and low-LET radiation
-
Rydberg B., Cooper B., Cooper P.K., Holley W.R., Chatterjee A. Dose-dependent misrejoining of radiation-induced DNA double-strand breaks in human fibroblasts: experimental and theoretical study for high- and low-LET radiation. Radiat. Res. 2005, 163:526-534.
-
(2005)
Radiat. Res.
, vol.163
, pp. 526-534
-
-
Rydberg, B.1
Cooper, B.2
Cooper, P.K.3
Holley, W.R.4
Chatterjee, A.5
-
9
-
-
42949157403
-
Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts
-
Asaithamby A., Uematsu N., Chatterjee A., Story M.D., Burma S., Chen D.J. Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts. Radiat. Res. 2008, 169:437-446.
-
(2008)
Radiat. Res.
, vol.169
, pp. 437-446
-
-
Asaithamby, A.1
Uematsu, N.2
Chatterjee, A.3
Story, M.D.4
Burma, S.5
Chen, D.J.6
-
10
-
-
0141541828
-
Biological effectiveness of accelerated particles for the induction of chromosome damage measured in metaphase and interphase human lymphocytes
-
George K., Durante M., Willingham V., Wu H., Yang T.C., Cucinotta F.A. Biological effectiveness of accelerated particles for the induction of chromosome damage measured in metaphase and interphase human lymphocytes. Radiat. Res. 2003, 160:425-435.
-
(2003)
Radiat. Res.
, vol.160
, pp. 425-435
-
-
George, K.1
Durante, M.2
Willingham, V.3
Wu, H.4
Yang, T.C.5
Cucinotta, F.A.6
-
11
-
-
0027976408
-
Initial events in the cellular effects of ionizing radiations: clustered damage in DNA
-
Goodhead D.T. Initial events in the cellular effects of ionizing radiations: clustered damage in DNA. Int. J. Radiat. Biol. 1994, 65:7-17.
-
(1994)
Int. J. Radiat. Biol.
, vol.65
, pp. 7-17
-
-
Goodhead, D.T.1
-
12
-
-
0027105878
-
Biochemical mechanisms and clusters of damage for high-LET radiation
-
Chatterjee A., Holley W.R. Biochemical mechanisms and clusters of damage for high-LET radiation. Adv. Space Res. 1992, 12:33-43.
-
(1992)
Adv. Space Res.
, vol.12
, pp. 33-43
-
-
Chatterjee, A.1
Holley, W.R.2
-
13
-
-
0017167303
-
Microdosimetric structure of heavy ion tracks in tissue
-
Chatterjee A., Schaefer H.J. Microdosimetric structure of heavy ion tracks in tissue. Radiat. Environ. Biophys. 1976, 13:215-227.
-
(1976)
Radiat. Environ. Biophys.
, vol.13
, pp. 215-227
-
-
Chatterjee, A.1
Schaefer, H.J.2
-
14
-
-
0026647099
-
Constraints on energy deposition and target size of multiply damaged sites associated with DNA double-strand breaks
-
Brenner D.J., Ward J.F. Constraints on energy deposition and target size of multiply damaged sites associated with DNA double-strand breaks. Int. J. Radiat. Biol. 1992, 61:737-748.
-
(1992)
Int. J. Radiat. Biol.
, vol.61
, pp. 737-748
-
-
Brenner, D.J.1
Ward, J.F.2
-
15
-
-
0034602643
-
Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation
-
Sutherland B.M., Bennett P.V., Sidorkina O., Laval J. Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:103-108.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 103-108
-
-
Sutherland, B.M.1
Bennett, P.V.2
Sidorkina, O.3
Laval, J.4
-
16
-
-
44349188585
-
Formation of clustered DNA damage after high-LET irradiation: a review
-
Hada M., Georgakilas A.G. Formation of clustered DNA damage after high-LET irradiation: a review. J. Radiat. Res. (Tokyo) 2008, 49:203-210.
-
(2008)
J. Radiat. Res. (Tokyo)
, vol.49
, pp. 203-210
-
-
Hada, M.1
Georgakilas, A.G.2
-
17
-
-
0034846440
-
Clustered DNA damages induced by high and low LET radiation, including heavy ions
-
Sutherland B.M., Bennett P.V., Schenk H., Sidorkina O., Laval J., Trunk J., Monteleone D., Sutherland J. Clustered DNA damages induced by high and low LET radiation, including heavy ions. Phys. Med. 2001, 17(Suppl. 1):202-204.
-
(2001)
Phys. Med.
, vol.17
, Issue.SUPPL. 1
, pp. 202-204
-
-
Sutherland, B.M.1
Bennett, P.V.2
Schenk, H.3
Sidorkina, O.4
Laval, J.5
Trunk, J.6
Monteleone, D.7
Sutherland, J.8
-
18
-
-
0035178567
-
Base excision repair processing of radiation-induced clustered DNA lesions
-
Blaisdell J.O., Harrison L., Wallace S.S. Base excision repair processing of radiation-induced clustered DNA lesions. Radiat. Prot. Dosim. 2001, 97:25-31.
-
(2001)
Radiat. Prot. Dosim.
, vol.97
, pp. 25-31
-
-
Blaisdell, J.O.1
Harrison, L.2
Wallace, S.S.3
-
19
-
-
0032519310
-
Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII
-
Harrison L., Hatahet Z., Purmal A.A., Wallace S.S. Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII. Nucleic Acids Res. 1998, 26:932-941.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 932-941
-
-
Harrison, L.1
Hatahet, Z.2
Purmal, A.A.3
Wallace, S.S.4
-
20
-
-
33846841032
-
Detection of oxidative clustered DNA lesions in X-irradiated mouse skin tissues and human MCF-7 breast cancer cells
-
Gollapalle E., Wang R., Adetolu R., Tsao D., Francisco D., Sigounas G., Georgakilas A.G. Detection of oxidative clustered DNA lesions in X-irradiated mouse skin tissues and human MCF-7 breast cancer cells. Radiat. Res. 2007, 167:207-216.
-
(2007)
Radiat. Res.
, vol.167
, pp. 207-216
-
-
Gollapalle, E.1
Wang, R.2
Adetolu, R.3
Tsao, D.4
Francisco, D.5
Sigounas, G.6
Georgakilas, A.G.7
-
21
-
-
0024195429
-
DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability
-
Ward J.F. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. Prog. Nucleic Acid Res. Mol. Biol. 1988, 35:95-125.
-
(1988)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.35
, pp. 95-125
-
-
Ward, J.F.1
-
22
-
-
34347368952
-
Energy deposition stochastics and track structure: what about the target?
-
Goodhead D.T. Energy deposition stochastics and track structure: what about the target?. Radiat. Prot. Dosim. 2006, 122:3-15.
-
(2006)
Radiat. Prot. Dosim.
, vol.122
, pp. 3-15
-
-
Goodhead, D.T.1
-
23
-
-
0033019430
-
Quantitative modelling of DNA damage using Monte Carlo track structure method
-
Nikjoo H., O'Neill P., Terrissol M., Goodhead D.T. Quantitative modelling of DNA damage using Monte Carlo track structure method. Radiat. Environ. Biophys. 1999, 38:31-38.
-
(1999)
Radiat. Environ. Biophys.
, vol.38
, pp. 31-38
-
-
Nikjoo, H.1
O'Neill, P.2
Terrissol, M.3
Goodhead, D.T.4
-
24
-
-
0034753336
-
Computational approach for determining the spectrum of DNA damage induced by ionizing radiation
-
Nikjoo H., O'Neill P., Wilson W.E., Goodhead D.T. Computational approach for determining the spectrum of DNA damage induced by ionizing radiation. Radiat. Res. 2001, 156:577-583.
-
(2001)
Radiat. Res.
, vol.156
, pp. 577-583
-
-
Nikjoo, H.1
O'Neill, P.2
Wilson, W.E.3
Goodhead, D.T.4
-
25
-
-
0037080182
-
Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease
-
David-Cordonnier M.H., Cunniffe S.M., Hickson I.D., O'Neill P. Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease. Biochemistry 2002, 41:634-642.
-
(2002)
Biochemistry
, vol.41
, pp. 634-642
-
-
David-Cordonnier, M.H.1
Cunniffe, S.M.2
Hickson, I.D.3
O'Neill, P.4
-
26
-
-
0036682280
-
Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites
-
Gulston M., Fulford J., Jenner T., de Lara C., O'Neill P. Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites. Nucleic Acids Res. 2002, 30:3464-3472.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 3464-3472
-
-
Gulston, M.1
Fulford, J.2
Jenner, T.3
de Lara, C.4
O'Neill, P.5
-
27
-
-
11144272029
-
8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1
-
Lomax M.E., Salje H., Cunniffe S., O'Neill P. 8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1. Radiat. Res. 2005, 163:79-84.
-
(2005)
Radiat. Res.
, vol.163
, pp. 79-84
-
-
Lomax, M.E.1
Salje, H.2
Cunniffe, S.3
O'Neill, P.4
-
28
-
-
2542637919
-
Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation
-
Gulston M., de Lara C., Jenner T., Davis E., O'Neill P. Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation. Nucleic Acids Res. 2004, 32:1602-1609.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 1602-1609
-
-
Gulston, M.1
de Lara, C.2
Jenner, T.3
Davis, E.4
O'Neill, P.5
-
29
-
-
77950360354
-
Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage
-
Eccles L.J., Lomax M.E., O'Neill P. Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage. Nucleic Acids Res. 2010, 38:1123-1134.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 1123-1134
-
-
Eccles, L.J.1
Lomax, M.E.2
O'Neill, P.3
-
30
-
-
19644391375
-
Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site
-
Fujimoto H., Pinak M., Nemoto T., O'Neill P., Kume E., Saito K., Maekawa H. Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site. J. Comput. Chem. 2005, 26:788-798.
-
(2005)
J. Comput. Chem.
, vol.26
, pp. 788-798
-
-
Fujimoto, H.1
Pinak, M.2
Nemoto, T.3
O'Neill, P.4
Kume, E.5
Saito, K.6
Maekawa, H.7
-
31
-
-
0032788298
-
In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites
-
Harrison L., Hatahet Z., Wallace S.S. In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites. J. Mol. Biol. 1999, 290:667-684.
-
(1999)
J. Mol. Biol.
, vol.290
, pp. 667-684
-
-
Harrison, L.1
Hatahet, Z.2
Wallace, S.S.3
-
32
-
-
50849105384
-
DNA repair of clustered lesions in mammalian cells: involvement of non-homologous end-joining
-
Malyarchuk S., Castore R., Harrison L. DNA repair of clustered lesions in mammalian cells: involvement of non-homologous end-joining. Nucleic Acids Res. 2008, 36:4872-4882.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 4872-4882
-
-
Malyarchuk, S.1
Castore, R.2
Harrison, L.3
-
33
-
-
67949124717
-
Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic
-
Bellon S., Shikazono N., Cunniffe S., Lomax M., O'Neill P. Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic. Nucleic Acids Res. 2009, 37:4430-4440.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 4430-4440
-
-
Bellon, S.1
Shikazono, N.2
Cunniffe, S.3
Lomax, M.4
O'Neill, P.5
-
34
-
-
77951977494
-
Role of oxidatively induced DNA lesions in human pathogenesis
-
Sedelnikova O.A., Redon C.E., Dickey J.S., Nakamura A.J., Georgakilas A.G., Bonner W.M. Role of oxidatively induced DNA lesions in human pathogenesis. Mutat. Res. 2010, 704:152-159.
-
(2010)
Mutat. Res.
, vol.704
, pp. 152-159
-
-
Sedelnikova, O.A.1
Redon, C.E.2
Dickey, J.S.3
Nakamura, A.J.4
Georgakilas, A.G.5
Bonner, W.M.6
-
35
-
-
0027180956
-
Effects of radiations of different qualities on cells: molecular mechanisms of damage and repair
-
Goodhead D.T., Thacker J., Cox R., Weiss, Lecture Effects of radiations of different qualities on cells: molecular mechanisms of damage and repair. Int. J. Radiat. Biol. 1993, 63:543-556.
-
(1993)
Int. J. Radiat. Biol.
, vol.63
, pp. 543-556
-
-
Goodhead, D.T.1
Thacker, J.2
Cox, R.3
Weiss, L.4
-
36
-
-
0034876617
-
Securing genome stability by orchestrating DNA repair: removal of radiation-induced clustered lesions in DNA
-
Dianov G.L., O'Neill P., Goodhead D.T. Securing genome stability by orchestrating DNA repair: removal of radiation-induced clustered lesions in DNA. Bioessays 2001, 23:745-749.
-
(2001)
Bioessays
, vol.23
, pp. 745-749
-
-
Dianov, G.L.1
O'Neill, P.2
Goodhead, D.T.3
-
37
-
-
0027172363
-
DNA strand break induction and rejoining and cellular recovery in mammalian cells after heavy-ion irradiation
-
Heilmann J., Rink H., Taucher-Scholz G., Kraft G. DNA strand break induction and rejoining and cellular recovery in mammalian cells after heavy-ion irradiation. Radiat. Res. 1993, 135:46-55.
-
(1993)
Radiat. Res.
, vol.135
, pp. 46-55
-
-
Heilmann, J.1
Rink, H.2
Taucher-Scholz, G.3
Kraft, G.4
-
38
-
-
0029684225
-
Induction and rejoining of DNA double-strand breaks in CHO cells after heavy ion irradiation
-
Taucher-Scholz G., Heilmann J., Kraft G. Induction and rejoining of DNA double-strand breaks in CHO cells after heavy ion irradiation. Adv. Space Res. 1996, 18:83-92.
-
(1996)
Adv. Space Res.
, vol.18
, pp. 83-92
-
-
Taucher-Scholz, G.1
Heilmann, J.2
Kraft, G.3
-
39
-
-
0038301384
-
Biological imaging of heavy charged-particle tracks
-
Jakob B., Scholz M., Taucher-Scholz G. Biological imaging of heavy charged-particle tracks. Radiat. Res. 2003, 159:676-684.
-
(2003)
Radiat. Res.
, vol.159
, pp. 676-684
-
-
Jakob, B.1
Scholz, M.2
Taucher-Scholz, G.3
-
40
-
-
25444502873
-
Immunofluorescence detection of clustered gamma-H2AX foci induced by HZE-particle radiation
-
Desai N., Davis E., O'Neill P., Durante M., Cucinotta F.A., Wu H. Immunofluorescence detection of clustered gamma-H2AX foci induced by HZE-particle radiation. Radiat. Res. 2005, 164:518-522.
-
(2005)
Radiat. Res.
, vol.164
, pp. 518-522
-
-
Desai, N.1
Davis, E.2
O'Neill, P.3
Durante, M.4
Cucinotta, F.A.5
Wu, H.6
-
41
-
-
3042805315
-
Focus formation of DNA repair proteins in normal and repair-deficient cells irradiated with high-LET ions
-
Karlsson K.H., Stenerlow B. Focus formation of DNA repair proteins in normal and repair-deficient cells irradiated with high-LET ions. Radiat. Res. 2004, 161:517-527.
-
(2004)
Radiat. Res.
, vol.161
, pp. 517-527
-
-
Karlsson, K.H.1
Stenerlow, B.2
-
42
-
-
29644443959
-
Repair of DNA damage induced by accelerated heavy ions in mammalian cells proficient and deficient in the non-homologous end-joining pathway
-
Okayasu R., Okada M., Okabe A., Noguchi M., Takakura K., Takahashi S. Repair of DNA damage induced by accelerated heavy ions in mammalian cells proficient and deficient in the non-homologous end-joining pathway. Radiat. Res. 2006, 165:59-67.
-
(2006)
Radiat. Res.
, vol.165
, pp. 59-67
-
-
Okayasu, R.1
Okada, M.2
Okabe, A.3
Noguchi, M.4
Takakura, K.5
Takahashi, S.6
-
43
-
-
0035179204
-
Clustered DNA damages as dosemeters for ionising radiation exposure and biological responses
-
Sutherland B.M., Bennett P.V., Saparbaev M., Sutherland J.C., Laval J. Clustered DNA damages as dosemeters for ionising radiation exposure and biological responses. Radiat. Prot. Dosim. 2001, 97:33-38.
-
(2001)
Radiat. Prot. Dosim.
, vol.97
, pp. 33-38
-
-
Sutherland, B.M.1
Bennett, P.V.2
Saparbaev, M.3
Sutherland, J.C.4
Laval, J.5
-
44
-
-
0345016976
-
Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis
-
Sutherland B.M., Georgakilas A.G., Bennett P.V., Laval J., Sutherland J.C. Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis. Mutat. Res. 2003, 531:93-107.
-
(2003)
Mutat. Res.
, vol.531
, pp. 93-107
-
-
Sutherland, B.M.1
Georgakilas, A.G.2
Bennett, P.V.3
Laval, J.4
Sutherland, J.C.5
-
45
-
-
0036639367
-
High efficiency detection of bi-stranded abasic clusters in gamma-irradiated DNA by putrescine
-
Georgakilas A.G., Bennett P.V., Sutherland B.M. High efficiency detection of bi-stranded abasic clusters in gamma-irradiated DNA by putrescine. Nucleic Acids Res. 2002, 30:2800-2808.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 2800-2808
-
-
Georgakilas, A.G.1
Bennett, P.V.2
Sutherland, B.M.3
-
46
-
-
6944248997
-
Processing of bistranded abasic DNA clusters in gamma-irradiated human hematopoietic cells
-
Georgakilas A.G., Bennett P.V., Wilson D.M., Sutherland B.M. Processing of bistranded abasic DNA clusters in gamma-irradiated human hematopoietic cells. Nucleic Acids Res. 2004, 32:5609-5620.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 5609-5620
-
-
Georgakilas, A.G.1
Bennett, P.V.2
Wilson, D.M.3
Sutherland, B.M.4
-
47
-
-
21044439508
-
Evaluation of lesion clustering in irradiated plasmid DNA
-
Leloup C., Garty G., Assaf G., Cristovao A., Breskin A., Chechik R., Shchemelinin S., Paz-Elizur T., Livneh Z., Schulte R.W., Bashkirov V., Milligan J.R., Grosswendt B. Evaluation of lesion clustering in irradiated plasmid DNA. Int. J. Radiat. Biol. 2005, 81:41-54.
-
(2005)
Int. J. Radiat. Biol.
, vol.81
, pp. 41-54
-
-
Leloup, C.1
Garty, G.2
Assaf, G.3
Cristovao, A.4
Breskin, A.5
Chechik, R.6
Shchemelinin, S.7
Paz-Elizur, T.8
Livneh, Z.9
Schulte, R.W.10
Bashkirov, V.11
Milligan, J.R.12
Grosswendt, B.13
-
48
-
-
0035912756
-
Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
-
Blaisdell J.O., Wallace S.S. Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:7426-7430.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 7426-7430
-
-
Blaisdell, J.O.1
Wallace, S.S.2
-
49
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou E.P., Boon C., Redon C., Bonner W.M. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 1999, 146:905-916.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
50
-
-
17644384427
-
Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks
-
Chen B.P., Chan D.W., Kobayashi J., Burma S., Asaithamby A., Morotomi-Yano K., Botvinick E., Qin J., Chen D.J. Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks. J. Biol. Chem. 2005, 280:14709-14715.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14709-14715
-
-
Chen, B.P.1
Chan, D.W.2
Kobayashi, J.3
Burma, S.4
Asaithamby, A.5
Morotomi-Yano, K.6
Botvinick, E.7
Qin, J.8
Chen, D.J.9
-
51
-
-
0034739853
-
P53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
-
Schultz L.B., Chehab N.H., Malikzay A., Halazonetis T.D. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J. Cell Biol. 2000, 151:1381-1390.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1381-1390
-
-
Schultz, L.B.1
Chehab, N.H.2
Malikzay, A.3
Halazonetis, T.D.4
-
52
-
-
67651162117
-
Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation
-
Asaithamby A., Chen D.J. Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation. Nucleic Acids Res. 2009, 37:3912-3923.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 3912-3923
-
-
Asaithamby, A.1
Chen, D.J.2
-
53
-
-
0034693220
-
Cellular responses and repair of single-strand breaks introduced by UV damage endonuclease in mammalian cells
-
Okano S., Kanno S., Nakajima S., Yasui A. Cellular responses and repair of single-strand breaks introduced by UV damage endonuclease in mammalian cells. J. Biol. Chem. 2000, 275:32635-32641.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32635-32641
-
-
Okano, S.1
Kanno, S.2
Nakajima, S.3
Yasui, A.4
-
54
-
-
3142540608
-
Are endogenous clustered DNA damages induced in human cells?
-
Bennett P.V., Cintron N.S., Gros L., Laval J., Sutherland B.M. Are endogenous clustered DNA damages induced in human cells?. Free Radic Biol. Med. 2004, 37:488-499.
-
(2004)
Free Radic Biol. Med.
, vol.37
, pp. 488-499
-
-
Bennett, P.V.1
Cintron, N.S.2
Gros, L.3
Laval, J.4
Sutherland, B.M.5
-
55
-
-
38049183244
-
XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks
-
Horton J.K., Watson M., Stefanick D.F., Shaughnessy D.T., Taylor J.A., Wilson S.H. XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks. Cell Res. 2008, 18:48-63.
-
(2008)
Cell Res.
, vol.18
, pp. 48-63
-
-
Horton, J.K.1
Watson, M.2
Stefanick, D.F.3
Shaughnessy, D.T.4
Taylor, J.A.5
Wilson, S.H.6
-
56
-
-
4644364562
-
In situ analysis of repair processes for oxidative DNA damage in mammalian cells
-
Lan L., Nakajima S., Oohata Y., Takao M., Okano S., Masutani M., Wilson S.H., Yasui A. In situ analysis of repair processes for oxidative DNA damage in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:13738-13743.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 13738-13743
-
-
Lan, L.1
Nakajima, S.2
Oohata, Y.3
Takao, M.4
Okano, S.5
Masutani, M.6
Wilson, S.H.7
Yasui, A.8
-
57
-
-
33846782890
-
UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles
-
Campalans A., Amouroux R., Bravard A., Epe B., Radicella J.P. UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles. J. Cell Sci. 2007, 120:23-32.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 23-32
-
-
Campalans, A.1
Amouroux, R.2
Bravard, A.3
Epe, B.4
Radicella, J.P.5
-
58
-
-
77955640606
-
Fluorescent proteins and their applications in imaging living cells and tissues
-
Chudakov D.M., Matz M.V., Lukyanov S., Lukyanov K.A. Fluorescent proteins and their applications in imaging living cells and tissues. Physiol. Rev. 2010, 90:1103-1163.
-
(2010)
Physiol. Rev.
, vol.90
, pp. 1103-1163
-
-
Chudakov, D.M.1
Matz, M.V.2
Lukyanov, S.3
Lukyanov, K.A.4
-
59
-
-
65249161170
-
Assembly of multiprotein complexes that control genome function
-
Dinant C., Luijsterburg M.S., Hofer T., von Bornstaedt G., Vermeulen W., Houtsmuller A.B., van Driel R. Assembly of multiprotein complexes that control genome function. J. Cell Biol. 2009, 185:21-26.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 21-26
-
-
Dinant, C.1
Luijsterburg, M.S.2
Hofer, T.3
von Bornstaedt, G.4
Vermeulen, W.5
Houtsmuller, A.B.6
van Driel, R.7
-
60
-
-
19544376983
-
Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy
-
Jakob B., Rudolph J.H., Gueven N., Lavin M.F., Taucher-Scholz G. Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy. Radiat. Res. 2005, 163:681-690.
-
(2005)
Radiat. Res.
, vol.163
, pp. 681-690
-
-
Jakob, B.1
Rudolph, J.H.2
Gueven, N.3
Lavin, M.F.4
Taucher-Scholz, G.5
-
61
-
-
34247477667
-
Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks
-
Uematsu N., Weterings E., Yano K., Morotomi-Yano K., Jakob B., Taucher-Scholz G., Mari P.O., van Gent D.C., Chen B.P., Chen D.J. Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks. J. Cell Biol. 2007, 177:219-229.
-
(2007)
J. Cell Biol.
, vol.177
, pp. 219-229
-
-
Uematsu, N.1
Weterings, E.2
Yano, K.3
Morotomi-Yano, K.4
Jakob, B.5
Taucher-Scholz, G.6
Mari, P.O.7
van Gent, D.C.8
Chen, B.P.9
Chen, D.J.10
-
62
-
-
77952095382
-
Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization
-
Costes S.V., Chiolo I., Pluth J.M., Barcellos-Hoff M.H., Jakob B. Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization. Mutat. Res. 2010, 704:78-87.
-
(2010)
Mutat. Res.
, vol.704
, pp. 78-87
-
-
Costes, S.V.1
Chiolo, I.2
Pluth, J.M.3
Barcellos-Hoff, M.H.4
Jakob, B.5
-
63
-
-
34548414588
-
Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains
-
Costes S.V., Ponomarev A., Chen J.L., Nguyen D., Cucinotta F.A., Barcellos-Hoff M.H. Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains. PLoS Comput. Biol. 2007, 3:e155.
-
(2007)
PLoS Comput. Biol.
, vol.3
-
-
Costes, S.V.1
Ponomarev, A.2
Chen, J.L.3
Nguyen, D.4
Cucinotta, F.A.5
Barcellos-Hoff, M.H.6
-
64
-
-
47349107760
-
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
-
Goodarzi A.A., Noon A.T., Deckbar D., Ziv Y., Shiloh Y., Lobrich M., Jeggo P.A. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell 2008, 31:167-177.
-
(2008)
Mol. Cell
, vol.31
, pp. 167-177
-
-
Goodarzi, A.A.1
Noon, A.T.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
Lobrich, M.6
Jeggo, P.A.7
-
65
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
Schotta G., Lachner M., Sarma K., Ebert A., Sengupta R., Reuter G., Reinberg D., Jenuwein T. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev. 2004, 18:1251-1262.
-
(2004)
Genes Dev.
, vol.18
, pp. 1251-1262
-
-
Schotta, G.1
Lachner, M.2
Sarma, K.3
Ebert, A.4
Sengupta, R.5
Reuter, G.6
Reinberg, D.7
Jenuwein, T.8
-
66
-
-
77952089468
-
Spatiotemporal analysis of DNA repair using charged particle radiation
-
Tobias F., Durante M., Taucher-Scholz G., Jakob B. Spatiotemporal analysis of DNA repair using charged particle radiation. Mutat. Res. 2010, 704:54-60.
-
(2010)
Mutat. Res.
, vol.704
, pp. 54-60
-
-
Tobias, F.1
Durante, M.2
Taucher-Scholz, G.3
Jakob, B.4
-
67
-
-
33846230598
-
Homology-directed repair is required for the development of radioresistance during S phase: interplay between double-strand break repair and checkpoint response
-
Tamulevicius P., Wang M., Iliakis G. Homology-directed repair is required for the development of radioresistance during S phase: interplay between double-strand break repair and checkpoint response. Radiat. Res. 2007, 167:1-11.
-
(2007)
Radiat. Res.
, vol.167
, pp. 1-11
-
-
Tamulevicius, P.1
Wang, M.2
Iliakis, G.3
-
68
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan M.E., Jasin M. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat. Rev. Mol. Cell Biol. 2010, 11:196-207.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
69
-
-
0034951142
-
Double-strand-break-induced homologous recombination in mammalian cells
-
Johnson R.D., Jasin M. Double-strand-break-induced homologous recombination in mammalian cells. Biochem. Soc. Trans. 2001, 29:196-201.
-
(2001)
Biochem. Soc. Trans.
, vol.29
, pp. 196-201
-
-
Johnson, R.D.1
Jasin, M.2
-
70
-
-
33846684170
-
Molecular mechanisms of sister-chromatid exchange
-
Wilson D.M., Thompson L.H. Molecular mechanisms of sister-chromatid exchange. Mutat. Res. 2007, 616:11-23.
-
(2007)
Mutat. Res.
, vol.616
, pp. 11-23
-
-
Wilson, D.M.1
Thompson, L.H.2
-
71
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 2010, 79:181-211.
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
72
-
-
0042632901
-
Pathways of DNA double-strand break repair during the mammalian cell cycle
-
Rothkamm K., Kruger I., Thompson L.H., Lobrich M. Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol. Cell. Biol. 2003, 23:5706-5715.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5706-5715
-
-
Rothkamm, K.1
Kruger, I.2
Thompson, L.H.3
Lobrich, M.4
-
73
-
-
0025853166
-
Response of X-ray-sensitive CHO mutant cells (xrs-6c) to radiation. II. Relationship between cell survival and the induction of chromosomal damage with low doses of alpha particles
-
Nagasawa H., Little J.B., Inkret W.C., Carpenter S., Raju M.R., Chen D.J., Strniste G.F. Response of X-ray-sensitive CHO mutant cells (xrs-6c) to radiation. II. Relationship between cell survival and the induction of chromosomal damage with low doses of alpha particles. Radiat. Res. 1991, 126:280-288.
-
(1991)
Radiat. Res.
, vol.126
, pp. 280-288
-
-
Nagasawa, H.1
Little, J.B.2
Inkret, W.C.3
Carpenter, S.4
Raju, M.R.5
Chen, D.J.6
Strniste, G.F.7
-
74
-
-
20644450114
-
Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells
-
Hinz J.M., Yamada N.A., Salazar E.P., Tebbs R.S., Thompson L.H. Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells. DNA Repair (Amst.) 2005, 4:782-792.
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 782-792
-
-
Hinz, J.M.1
Yamada, N.A.2
Salazar, E.P.3
Tebbs, R.S.4
Thompson, L.H.5
-
75
-
-
3042577121
-
Persistence of chromosome aberrations in mice acutely exposed to 56Fe+26 ions
-
Tucker J.D., Marples B., Ramsey M.J., Lutze-Mann L.H. Persistence of chromosome aberrations in mice acutely exposed to 56Fe+26 ions. Radiat. Res. 2004, 161:648-655.
-
(2004)
Radiat. Res.
, vol.161
, pp. 648-655
-
-
Tucker, J.D.1
Marples, B.2
Ramsey, M.J.3
Lutze-Mann, L.H.4
-
76
-
-
42249098075
-
The Ku-dependent non-homologous end-joining but not other repair pathway is inhibited by high linear energy transfer ionizing radiation
-
Wang H., Wang X., Zhang P., Wang Y. The Ku-dependent non-homologous end-joining but not other repair pathway is inhibited by high linear energy transfer ionizing radiation. DNA Repair (Amst.) 2008, 7:725-733.
-
(2008)
DNA Repair (Amst.)
, vol.7
, pp. 725-733
-
-
Wang, H.1
Wang, X.2
Zhang, P.3
Wang, Y.4
-
77
-
-
77953716710
-
Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation
-
Wang H., Zhang X., Wang P., Yu X., Essers J., Chen D., Kanaar R., Takeda S., Wang Y. Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation. Nucleic Acids Res. 2010, 38:3245-3251.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 3245-3251
-
-
Wang, H.1
Zhang, X.2
Wang, P.3
Yu, X.4
Essers, J.5
Chen, D.6
Kanaar, R.7
Takeda, S.8
Wang, Y.9
-
78
-
-
0038799991
-
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
-
Paques F., Haber J.E. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 1999, 63:349-404.
-
(1999)
Microbiol. Mol. Biol. Rev.
, vol.63
, pp. 349-404
-
-
Paques, F.1
Haber, J.E.2
-
79
-
-
0035695023
-
Recombination at double-strand breaks and DNA ends: conserved mechanisms from phage to humans
-
Cromie G.A., Connelly J.C., Leach D.R. Recombination at double-strand breaks and DNA ends: conserved mechanisms from phage to humans. Mol. Cell 2001, 8:1163-1174.
-
(2001)
Mol. Cell
, vol.8
, pp. 1163-1174
-
-
Cromie, G.A.1
Connelly, J.C.2
Leach, D.R.3
-
80
-
-
30644474016
-
The human pre-B cell line Nalm-6 is highly proficient in gene targeting by homologous recombination
-
Adachi N., So S., Iiizumi S., Nomura Y., Murai K., Yamakawa C., Miyagawa K., Koyama H. The human pre-B cell line Nalm-6 is highly proficient in gene targeting by homologous recombination. DNA Cell Biol. 2006, 25:19-24.
-
(2006)
DNA Cell Biol.
, vol.25
, pp. 19-24
-
-
Adachi, N.1
So, S.2
Iiizumi, S.3
Nomura, Y.4
Murai, K.5
Yamakawa, C.6
Miyagawa, K.7
Koyama, H.8
-
81
-
-
2642573591
-
Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells
-
Couedel C., Mills K.D., Barchi M., Shen L., Olshen A., Johnson R.D., Nussenzweig A., Essers J., Kanaar R., Li G.C., Alt F.W., Jasin M. Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. Genes Dev. 2004, 18:1293-1304.
-
(2004)
Genes Dev.
, vol.18
, pp. 1293-1304
-
-
Couedel, C.1
Mills, K.D.2
Barchi, M.3
Shen, L.4
Olshen, A.5
Johnson, R.D.6
Nussenzweig, A.7
Essers, J.8
Kanaar, R.9
Li, G.C.10
Alt, F.W.11
Jasin, M.12
-
82
-
-
77955841149
-
Collaboration and competition between DNA double-strand break repair pathways
-
Kass E.M., Jasin M. Collaboration and competition between DNA double-strand break repair pathways. FEBS Lett. 2010, 584:3703-3708.
-
(2010)
FEBS Lett.
, vol.584
, pp. 3703-3708
-
-
Kass, E.M.1
Jasin, M.2
-
83
-
-
38049155945
-
Regulation of DNA double-strand break repair pathway choice
-
Shrivastav M., De Haro L.P., Nickoloff J.A. Regulation of DNA double-strand break repair pathway choice. Cell Res. 2008, 18:134-147.
-
(2008)
Cell Res.
, vol.18
, pp. 134-147
-
-
Shrivastav, M.1
De Haro, L.P.2
Nickoloff, J.A.3
-
84
-
-
77954313601
-
DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints
-
You Z., Bailis J.M. DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints. Trends Cell Biol. 2010, 20:402-409.
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 402-409
-
-
You, Z.1
Bailis, J.M.2
-
85
-
-
0037133699
-
DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination
-
Allen C., Kurimasa A., Brenneman M.A., Chen D.J., Nickoloff J.A. DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:3758-3763.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 3758-3763
-
-
Allen, C.1
Kurimasa, A.2
Brenneman, M.A.3
Chen, D.J.4
Nickoloff, J.A.5
-
86
-
-
0035893363
-
End-binding protein modulates homologous repair of double-strand breaks in mammalian cells
-
Pierce A.J., Hu P., Han M., Ellis N., Jasin M., Ku D.N.A. end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev. 2001, 15:3237-3242.
-
(2001)
Genes Dev.
, vol.15
, pp. 3237-3242
-
-
Pierce, A.J.1
Hu, P.2
Han, M.3
Ellis, N.4
Jasin, M.5
Ku, D.N.A.6
-
87
-
-
2642511410
-
Induction of homologous recombination in the hprt gene of V79 Chinese hamster cells in response to low- and high-LET irradiation
-
Olsson G., Czene S., Jenssen D., Harms-Ringdahl M. Induction of homologous recombination in the hprt gene of V79 Chinese hamster cells in response to low- and high-LET irradiation. Cytogenet. Genome Res. 2004, 104:227-231.
-
(2004)
Cytogenet. Genome Res.
, vol.104
, pp. 227-231
-
-
Olsson, G.1
Czene, S.2
Jenssen, D.3
Harms-Ringdahl, M.4
-
88
-
-
73349132033
-
Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions
-
Zafar F., Seidler S.B., Kronenberg A., Schild D., Wiese C. Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions. Radiat. Res. 2010, 173:27-39.
-
(2010)
Radiat. Res.
, vol.173
, pp. 27-39
-
-
Zafar, F.1
Seidler, S.B.2
Kronenberg, A.3
Schild, D.4
Wiese, C.5
-
89
-
-
0037314536
-
Repair of radiation-induced DNA double-strand breaks is dependent upon radiation quality and the structural complexity of double-strand breaks
-
Pastwa E., Neumann R.D., Mezhevaya K., Winters T.A. Repair of radiation-induced DNA double-strand breaks is dependent upon radiation quality and the structural complexity of double-strand breaks. Radiat. Res. 2003, 159:251-261.
-
(2003)
Radiat. Res.
, vol.159
, pp. 251-261
-
-
Pastwa, E.1
Neumann, R.D.2
Mezhevaya, K.3
Winters, T.A.4
-
90
-
-
0030743386
-
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
-
Grawunder U., Wilm M., Wu X., Kulesza P., Wilson T.E., Mann M., Lieber M.R. Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature 1997, 388:492-495.
-
(1997)
Nature
, vol.388
, pp. 492-495
-
-
Grawunder, U.1
Wilm, M.2
Wu, X.3
Kulesza, P.4
Wilson, T.E.5
Mann, M.6
Lieber, M.R.7
-
91
-
-
0037115920
-
Structure and function of nucleases in DNA repair: shape, grip and blade of the DNA scissors
-
Nishino T., Morikawa K. Structure and function of nucleases in DNA repair: shape, grip and blade of the DNA scissors. Oncogene 2002, 21:9022-9032.
-
(2002)
Oncogene
, vol.21
, pp. 9022-9032
-
-
Nishino, T.1
Morikawa, K.2
-
92
-
-
0030691121
-
Hierarchical deterioration of body systems in Werner's syndrome: implications for normal ageing
-
Goto M. Hierarchical deterioration of body systems in Werner's syndrome: implications for normal ageing. Mech. Ageing Dev. 1997, 98:239-254.
-
(1997)
Mech. Ageing Dev.
, vol.98
, pp. 239-254
-
-
Goto, M.1
-
93
-
-
76749168005
-
Roles of Werner syndrome protein in protection of genome integrity
-
Rossi M.L., Ghosh A.K., Bohr V.A. Roles of Werner syndrome protein in protection of genome integrity. DNA Repair (Amst.) 2010, 9:331-344.
-
(2010)
DNA Repair (Amst.)
, vol.9
, pp. 331-344
-
-
Rossi, M.L.1
Ghosh, A.K.2
Bohr, V.A.3
-
94
-
-
0031686571
-
The premature ageing syndrome protein, WRN, is a 3′->5′ exonuclease
-
Huang S., Li B., Gray M.D., Oshima J., Mian I.S., Campisi J. The premature ageing syndrome protein, WRN, is a 3′->5′ exonuclease. Nat. Genet. 1998, 20:114-116.
-
(1998)
Nat. Genet.
, vol.20
, pp. 114-116
-
-
Huang, S.1
Li, B.2
Gray, M.D.3
Oshima, J.4
Mian, I.S.5
Campisi, J.6
-
95
-
-
0347362703
-
Werner syndrome protein contains three structure-specific DNA binding domains
-
von Kobbe C., Thoma N.H., Czyzewski B.K., Pavletich N.P., Bohr V.A. Werner syndrome protein contains three structure-specific DNA binding domains. J. Biol. Chem. 2003, 278:52997-53006.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 52997-53006
-
-
von Kobbe, C.1
Thoma, N.H.2
Czyzewski, B.K.3
Pavletich, N.P.4
Bohr, V.A.5
-
96
-
-
42049116919
-
The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest
-
Sidorova J.M., Li N., Folch A., Monnat R.J. The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest. Cell Cycle 2008, 7:796-807.
-
(2008)
Cell Cycle
, vol.7
, pp. 796-807
-
-
Sidorova, J.M.1
Li, N.2
Folch, A.3
Monnat, R.J.4
-
97
-
-
77955480303
-
Identification of a coiled coil in Werner syndrome protein that facilitates multimerization and promotes exonuclease processivity
-
Perry J.J., Asaithamby A., Barnebey A., Kiamanesch F., Chen D.J., Han S., Tainer J.A., Yannone S.M. Identification of a coiled coil in Werner syndrome protein that facilitates multimerization and promotes exonuclease processivity. J. Biol. Chem. 2010, 285:25699-25707.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 25699-25707
-
-
Perry, J.J.1
Asaithamby, A.2
Barnebey, A.3
Kiamanesch, F.4
Chen, D.J.5
Han, S.6
Tainer, J.A.7
Yannone, S.M.8
-
98
-
-
62849091779
-
The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation
-
Opresko P.L., Sowd G., Wang H. The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation. PLoS One 2009, 4:e4825.
-
(2009)
PLoS One
, vol.4
-
-
Opresko, P.L.1
Sowd, G.2
Wang, H.3
-
99
-
-
0034655912
-
Ku complex interacts with and stimulates the Werner protein
-
Cooper M.P., Machwe A., Orren D.K., Brosh R.M., Ramsden D., Bohr V.A. Ku complex interacts with and stimulates the Werner protein. Genes Dev. 2000, 14:907-912.
-
(2000)
Genes Dev.
, vol.14
, pp. 907-912
-
-
Cooper, M.P.1
Machwe, A.2
Orren, D.K.3
Brosh, R.M.4
Ramsden, D.5
Bohr, V.A.6
-
100
-
-
0037166306
-
Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation
-
Karmakar P., Piotrowski J., Brosh R.M., Sommers J.A., Miller S.P., Cheng W.H., Snowden C.M., Ramsden D.A., Bohr V.A. Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation. J. Biol. Chem. 2002, 277:18291-18302.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18291-18302
-
-
Karmakar, P.1
Piotrowski, J.2
Brosh, R.M.3
Sommers, J.A.4
Miller, S.P.5
Cheng, W.H.6
Snowden, C.M.7
Ramsden, D.A.8
Bohr, V.A.9
-
101
-
-
0035851181
-
Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase
-
Yannone S.M., Roy S., Chan D.W., Murphy M.B., Huang S., Campisi J., Chen D.J. Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase. J. Biol. Chem. 2001, 276:38242-38248.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38242-38248
-
-
Yannone, S.M.1
Roy, S.2
Chan, D.W.3
Murphy, M.B.4
Huang, S.5
Campisi, J.6
Chen, D.J.7
-
102
-
-
0035009356
-
Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51
-
Sakamoto S., Nishikawa K., Heo S.J., Goto M., Furuichi Y., Shimamoto A. Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51. Genes Cells 2001, 6:421-430.
-
(2001)
Genes Cells
, vol.6
, pp. 421-430
-
-
Sakamoto, S.1
Nishikawa, K.2
Heo, S.J.3
Goto, M.4
Furuichi, Y.5
Shimamoto, A.6
-
103
-
-
77955055418
-
WRN participates in translesion synthesis pathway through interaction with NBS1
-
Kobayashi J., Okui M., Asaithamby A., Burma S., Chen B.P., Tanimoto K., Matsuura S., Komatsu K., Chen D.J. WRN participates in translesion synthesis pathway through interaction with NBS1. Mech. Ageing Dev. 2010, 131:436-444.
-
(2010)
Mech. Ageing Dev.
, vol.131
, pp. 436-444
-
-
Kobayashi, J.1
Okui, M.2
Asaithamby, A.3
Burma, S.4
Chen, B.P.5
Tanimoto, K.6
Matsuura, S.7
Komatsu, K.8
Chen, D.J.9
-
104
-
-
0141480945
-
WRN interacts physically and functionally with the recombination mediator protein RAD52
-
Baynton K., Otterlei M., Bjoras M., von Kobbe C., Bohr V.A., Seeberg E. WRN interacts physically and functionally with the recombination mediator protein RAD52. J. Biol. Chem. 2003, 278:36476-36486.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36476-36486
-
-
Baynton, K.1
Otterlei, M.2
Bjoras, M.3
von Kobbe, C.4
Bohr, V.A.5
Seeberg, E.6
-
105
-
-
33846141125
-
Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest
-
Otterlei M., Bruheim P., Ahn B., Bussen W., Karmakar P., Baynton K., Bohr V.A. Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest. J. Cell Sci. 2006, 119:5137-5146.
-
(2006)
J. Cell Sci.
, vol.119
, pp. 5137-5146
-
-
Otterlei, M.1
Bruheim, P.2
Ahn, B.3
Bussen, W.4
Karmakar, P.5
Baynton, K.6
Bohr, V.A.7
-
106
-
-
0036787870
-
Homologous recombination resolution defect in Werner syndrome
-
Saintigny Y., Makienko K., Swanson C., Emond M.J., Monnat R.J. Homologous recombination resolution defect in Werner syndrome. Mol. Cell. Biol. 2002, 22:6971-6978.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6971-6978
-
-
Saintigny, Y.1
Makienko, K.2
Swanson, C.3
Emond, M.J.4
Monnat, R.J.5
-
107
-
-
1842685207
-
The Werner syndrome protein has separable recombination and survival functions
-
Swanson C., Saintigny Y., Emond M.J., Monnat R.J. The Werner syndrome protein has separable recombination and survival functions. DNA Repair (Amst.) 2004, 3:475-482.
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 475-482
-
-
Swanson, C.1
Saintigny, Y.2
Emond, M.J.3
Monnat, R.J.4
-
108
-
-
0034231844
-
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest
-
Constantinou A., Tarsounas M., Karow J.K., Brosh R.M., Bohr V.A., Hickson I.D., West S.C. Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. EMBO Rep. 2000, 1:80-84.
-
(2000)
EMBO Rep.
, vol.1
, pp. 80-84
-
-
Constantinou, A.1
Tarsounas, M.2
Karow, J.K.3
Brosh, R.M.4
Bohr, V.A.5
Hickson, I.D.6
West, S.C.7
-
109
-
-
77956881105
-
ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery
-
Ammazzalorso F., Pirzio L.M., Bignami M., Franchitto A., Pichierri P. ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery. Embo J. 2010.
-
(2010)
Embo J.
-
-
Ammazzalorso, F.1
Pirzio, L.M.2
Bignami, M.3
Franchitto, A.4
Pichierri, P.5
-
110
-
-
33745084835
-
WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing
-
Perry J.J., Yannone S.M., Holden L.G., Hitomi C., Asaithamby A., Han S., Cooper P.K., Chen D.J., Tainer J.A. WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat. Struct. Mol. Biol. 2006, 13:414-422.
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 414-422
-
-
Perry, J.J.1
Yannone, S.M.2
Holden, L.G.3
Hitomi, C.4
Asaithamby, A.5
Han, S.6
Cooper, P.K.7
Chen, D.J.8
Tainer, J.A.9
-
111
-
-
0035917489
-
Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
-
Moshous D., Callebaut I., de Chasseval R., Corneo B., Cavazzana-Calvo M., Le Deist F., Tezcan I., Sanal O., Bertrand Y., Philippe N., Fischer A., de Villartay J.P. Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell 2001, 105:177-186.
-
(2001)
Cell
, vol.105
, pp. 177-186
-
-
Moshous, D.1
Callebaut, I.2
de Chasseval, R.3
Corneo, B.4
Cavazzana-Calvo, M.5
Le Deist, F.6
Tezcan, I.7
Sanal, O.8
Bertrand, Y.9
Philippe, N.10
Fischer, A.11
de Villartay, J.P.12
-
112
-
-
0037565312
-
The V(D)J recombination/DNA repair factor artemis belongs to the metallo-beta-lactamase family and constitutes a critical developmental checkpoint of the lymphoid system
-
Moshous D., Callebaut I., de Chasseval R., Poinsignon C., Villey I., Fischer A., de Villartay J.P. The V(D)J recombination/DNA repair factor artemis belongs to the metallo-beta-lactamase family and constitutes a critical developmental checkpoint of the lymphoid system. Ann. N. Y. Acad. Sci. 2003, 987:150-157.
-
(2003)
Ann. N. Y. Acad. Sci.
, vol.987
, pp. 150-157
-
-
Moshous, D.1
Callebaut, I.2
de Chasseval, R.3
Poinsignon, C.4
Villey, I.5
Fischer, A.6
de Villartay, J.P.7
-
113
-
-
70349574621
-
V(D)J recombination deficiencies
-
de Villartay J.P. V(D)J recombination deficiencies. Adv. Exp. Med. Biol. 2009, 650:46-58.
-
(2009)
Adv. Exp. Med. Biol.
, vol.650
, pp. 46-58
-
-
de Villartay, J.P.1
-
114
-
-
77958548176
-
Functions and regulation of artemis: a goddess in the maintenance of genome integrity
-
Kurosawa A., Adachi N. Functions and regulation of artemis: a goddess in the maintenance of genome integrity. J. Radiat. Res. (Tokyo) 2010.
-
(2010)
J. Radiat. Res. (Tokyo)
-
-
Kurosawa, A.1
Adachi, N.2
-
115
-
-
9744241712
-
A biochemically defined system for mammalian nonhomologous DNA end joining
-
Ma Y., Lu H., Tippin B., Goodman M.F., Shimazaki N., Koiwai O., Hsieh C.L., Schwarz K., Lieber M.R. A biochemically defined system for mammalian nonhomologous DNA end joining. Mol. Cell 2004, 16:701-713.
-
(2004)
Mol. Cell
, vol.16
, pp. 701-713
-
-
Ma, Y.1
Lu, H.2
Tippin, B.3
Goodman, M.F.4
Shimazaki, N.5
Koiwai, O.6
Hsieh, C.L.7
Schwarz, K.8
Lieber, M.R.9
-
116
-
-
20644463916
-
The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps
-
Ma Y., Schwarz K., Lieber M.R. The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps. DNA Repair (Amst.) 2005, 4:845-851.
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 845-851
-
-
Ma, Y.1
Schwarz, K.2
Lieber, M.R.3
-
117
-
-
77949658435
-
DNA-PKcs regulates a single-stranded DNA endonuclease activity of Artemis
-
Gu J., Li S., Zhang X., Wang L.C., Niewolik D., Schwarz K., Legerski R.J., Zandi E., Lieber M.R. DNA-PKcs regulates a single-stranded DNA endonuclease activity of Artemis. DNA Repair (Amst.) 2010, 9:429-437.
-
(2010)
DNA Repair (Amst.)
, vol.9
, pp. 429-437
-
-
Gu, J.1
Li, S.2
Zhang, X.3
Wang, L.C.4
Niewolik, D.5
Schwarz, K.6
Legerski, R.J.7
Zandi, E.8
Lieber, M.R.9
-
118
-
-
59849089955
-
Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
-
Mahaney B.L., Meek K., Lees-Miller S.P. Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem. J. 2009, 417:639-650.
-
(2009)
Biochem. J.
, vol.417
, pp. 639-650
-
-
Mahaney, B.L.1
Meek, K.2
Lees-Miller, S.P.3
-
119
-
-
3142555854
-
Functional and biochemical dissection of the structure-specific nuclease ARTEMIS
-
Pannicke U., Ma Y., Hopfner K.P., Niewolik D., Lieber M.R., Schwarz K. Functional and biochemical dissection of the structure-specific nuclease ARTEMIS. Embo J. 2004, 23:1987-1997.
-
(2004)
Embo J.
, vol.23
, pp. 1987-1997
-
-
Pannicke, U.1
Ma, Y.2
Hopfner, K.P.3
Niewolik, D.4
Lieber, M.R.5
Schwarz, K.6
-
120
-
-
33646090620
-
Artemis phosphorylated by DNA-dependent protein kinase associates preferentially with discrete regions of chromatin
-
Soubeyrand S., Pope L., De Chasseval R., Gosselin D., Dong F., de Villartay J.P., Hache R.J. Artemis phosphorylated by DNA-dependent protein kinase associates preferentially with discrete regions of chromatin. J. Mol. Biol. 2006, 358:1200-1211.
-
(2006)
J. Mol. Biol.
, vol.358
, pp. 1200-1211
-
-
Soubeyrand, S.1
Pope, L.2
De Chasseval, R.3
Gosselin, D.4
Dong, F.5
de Villartay, J.P.6
Hache, R.J.7
-
121
-
-
16244401671
-
Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression
-
Wang J., Pluth J.M., Cooper P.K., Cowan M.J., Chen D.J., Yannone S.M. Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression. DNA Repair (Amst.) 2005, 4:556-570.
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 556-570
-
-
Wang, J.1
Pluth, J.M.2
Cooper, P.K.3
Cowan, M.J.4
Chen, D.J.5
Yannone, S.M.6
-
122
-
-
9744220428
-
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci
-
Riballo E., Kuhne M., Rief N., Doherty A., Smith G.C., Recio M.J., Reis C., Dahm K., Fricke A., Krempler A., Parker A.R., Jackson S.P., Gennery A., Jeggo P.A., Lobrich M. A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol. Cell 2004, 16:715-724.
-
(2004)
Mol. Cell
, vol.16
, pp. 715-724
-
-
Riballo, E.1
Kuhne, M.2
Rief, N.3
Doherty, A.4
Smith, G.C.5
Recio, M.J.6
Reis, C.7
Dahm, K.8
Fricke, A.9
Krempler, A.10
Parker, A.R.11
Jackson, S.P.12
Gennery, A.13
Jeggo, P.A.14
Lobrich, M.15
-
123
-
-
25444475799
-
Repair of double-strand DNA breaks by the human nonhomologous DNA end joining pathway: the iterative processing model
-
Ma Y., Lu H., Schwarz K., Lieber M.R. Repair of double-strand DNA breaks by the human nonhomologous DNA end joining pathway: the iterative processing model. Cell Cycle 2005, 4:1193-1200.
-
(2005)
Cell Cycle
, vol.4
, pp. 1193-1200
-
-
Ma, Y.1
Lu, H.2
Schwarz, K.3
Lieber, M.R.4
-
124
-
-
34047153762
-
Functions and regulation of human artemis in double strand break repair
-
Dahm K. Functions and regulation of human artemis in double strand break repair. J. Cell. Biochem. 2007, 100:1346-1351.
-
(2007)
J. Cell. Biochem.
, vol.100
, pp. 1346-1351
-
-
Dahm, K.1
-
125
-
-
77957786786
-
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks
-
Shim E.Y., Chung W.H., Nicolette M.L., Zhang Y., Davis M., Zhu Z., Paull T.T., Ira G., Lee S.E. Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks. Embo J. 2010.
-
(2010)
Embo J.
-
-
Shim, E.Y.1
Chung, W.H.2
Nicolette, M.L.3
Zhang, Y.4
Davis, M.5
Zhu, Z.6
Paull, T.T.7
Ira, G.8
Lee, S.E.9
-
126
-
-
77952866393
-
More modifiers move on DNA damage
-
Morris J.R. More modifiers move on DNA damage. Cancer Res. 2010, 70:3861-3863.
-
(2010)
Cancer Res.
, vol.70
, pp. 3861-3863
-
-
Morris, J.R.1
-
128
-
-
67849119704
-
Comparison of several radiation effects in human MCF10A mammary epithelial cells cultured as 2D monolayers or 3D acinar stuctures in matrigel
-
Lin Y.F., Nagasawa H., Peng Y., Chuang E.Y., Bedford J.S. Comparison of several radiation effects in human MCF10A mammary epithelial cells cultured as 2D monolayers or 3D acinar stuctures in matrigel. Radiat. Res. 2009, 171:708-715.
-
(2009)
Radiat. Res.
, vol.171
, pp. 708-715
-
-
Lin, Y.F.1
Nagasawa, H.2
Peng, Y.3
Chuang, E.Y.4
Bedford, J.S.5
-
129
-
-
58349101767
-
Two- and three-dimensional models for risk assessment of radiation-enhanced colorectal tumorigenesis
-
Roig A.I., Hight S.K., Shay J.W. Two- and three-dimensional models for risk assessment of radiation-enhanced colorectal tumorigenesis. Radiat. Res. 2009, 171:33-40.
-
(2009)
Radiat. Res.
, vol.171
, pp. 33-40
-
-
Roig, A.I.1
Hight, S.K.2
Shay, J.W.3
-
130
-
-
62549130381
-
Live cell microscopy analysis of radiation-induced DNA double-strand break motion
-
Jakob B., Splinter J., Durante M., Taucher-Scholz G. Live cell microscopy analysis of radiation-induced DNA double-strand break motion. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:3172-3177.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 3172-3177
-
-
Jakob, B.1
Splinter, J.2
Durante, M.3
Taucher-Scholz, G.4
|