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Volumn 711, Issue 1-2, 2011, Pages 87-99

Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation

Author keywords

Clustered DNA damage; High LET; HZE particles; Ionizing radiation; Low LET; WRN and Artemis

Indexed keywords

ARTEMIS; DEOXYRIBONUCLEASE; PENICILLINASE; UNCLASSIFIED DRUG; WERNER SYNDROME PROTEIN;

EID: 79956187736     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2010.11.002     Document Type: Review
Times cited : (130)

References (130)
  • 1
    • 0023555502 scopus 로고
    • Radiation hazards on space missions
    • Letaw J.R., Silberberg R., Tsao C.H. Radiation hazards on space missions. Nature 1987, 330:709-710.
    • (1987) Nature , vol.330 , pp. 709-710
    • Letaw, J.R.1    Silberberg, R.2    Tsao, C.H.3
  • 2
  • 3
    • 77951298967 scopus 로고    scopus 로고
    • New radiobiological, radiation risk and radiation protection paradigms
    • Goodhead D.T. New radiobiological, radiation risk and radiation protection paradigms. Mutat. Res. 2010, 687:13-16.
    • (2010) Mutat. Res. , vol.687 , pp. 13-16
    • Goodhead, D.T.1
  • 4
    • 44349143334 scopus 로고    scopus 로고
    • Heavy ion carcinogenesis and human space exploration
    • Durante M., Cucinotta F.A. Heavy ion carcinogenesis and human space exploration. Nat. Rev. Cancer 2008, 8:465-472.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 465-472
    • Durante, M.1    Cucinotta, F.A.2
  • 5
    • 0024857545 scopus 로고
    • Galactic cosmic rays and cell-hit frequencies outside the magnetosphere
    • Curtis S.B., Letaw J.R. Galactic cosmic rays and cell-hit frequencies outside the magnetosphere. Adv. Space Res. 1989, 9:293-298.
    • (1989) Adv. Space Res. , vol.9 , pp. 293-298
    • Curtis, S.B.1    Letaw, J.R.2
  • 6
    • 0023750512 scopus 로고
    • Radiation protection guidelines for space missions
    • Fry R.J., Nachtwey D.S. Radiation protection guidelines for space missions. Health Phys. 1988, 55:159-164.
    • (1988) Health Phys. , vol.55 , pp. 159-164
    • Fry, R.J.1    Nachtwey, D.S.2
  • 7
    • 0242267007 scopus 로고    scopus 로고
    • The increased biological effectiveness of heavy charged particles: from radiobiology to treatment planning
    • Kramer M., Weyrather W.K., Scholz M. The increased biological effectiveness of heavy charged particles: from radiobiology to treatment planning. Technol. Cancer Res. Treat. 2003, 2:427-436.
    • (2003) Technol. Cancer Res. Treat. , vol.2 , pp. 427-436
    • Kramer, M.1    Weyrather, W.K.2    Scholz, M.3
  • 8
    • 19444362723 scopus 로고    scopus 로고
    • Dose-dependent misrejoining of radiation-induced DNA double-strand breaks in human fibroblasts: experimental and theoretical study for high- and low-LET radiation
    • Rydberg B., Cooper B., Cooper P.K., Holley W.R., Chatterjee A. Dose-dependent misrejoining of radiation-induced DNA double-strand breaks in human fibroblasts: experimental and theoretical study for high- and low-LET radiation. Radiat. Res. 2005, 163:526-534.
    • (2005) Radiat. Res. , vol.163 , pp. 526-534
    • Rydberg, B.1    Cooper, B.2    Cooper, P.K.3    Holley, W.R.4    Chatterjee, A.5
  • 9
  • 10
    • 0141541828 scopus 로고    scopus 로고
    • Biological effectiveness of accelerated particles for the induction of chromosome damage measured in metaphase and interphase human lymphocytes
    • George K., Durante M., Willingham V., Wu H., Yang T.C., Cucinotta F.A. Biological effectiveness of accelerated particles for the induction of chromosome damage measured in metaphase and interphase human lymphocytes. Radiat. Res. 2003, 160:425-435.
    • (2003) Radiat. Res. , vol.160 , pp. 425-435
    • George, K.1    Durante, M.2    Willingham, V.3    Wu, H.4    Yang, T.C.5    Cucinotta, F.A.6
  • 11
    • 0027976408 scopus 로고
    • Initial events in the cellular effects of ionizing radiations: clustered damage in DNA
    • Goodhead D.T. Initial events in the cellular effects of ionizing radiations: clustered damage in DNA. Int. J. Radiat. Biol. 1994, 65:7-17.
    • (1994) Int. J. Radiat. Biol. , vol.65 , pp. 7-17
    • Goodhead, D.T.1
  • 12
    • 0027105878 scopus 로고
    • Biochemical mechanisms and clusters of damage for high-LET radiation
    • Chatterjee A., Holley W.R. Biochemical mechanisms and clusters of damage for high-LET radiation. Adv. Space Res. 1992, 12:33-43.
    • (1992) Adv. Space Res. , vol.12 , pp. 33-43
    • Chatterjee, A.1    Holley, W.R.2
  • 13
    • 0017167303 scopus 로고
    • Microdosimetric structure of heavy ion tracks in tissue
    • Chatterjee A., Schaefer H.J. Microdosimetric structure of heavy ion tracks in tissue. Radiat. Environ. Biophys. 1976, 13:215-227.
    • (1976) Radiat. Environ. Biophys. , vol.13 , pp. 215-227
    • Chatterjee, A.1    Schaefer, H.J.2
  • 14
    • 0026647099 scopus 로고
    • Constraints on energy deposition and target size of multiply damaged sites associated with DNA double-strand breaks
    • Brenner D.J., Ward J.F. Constraints on energy deposition and target size of multiply damaged sites associated with DNA double-strand breaks. Int. J. Radiat. Biol. 1992, 61:737-748.
    • (1992) Int. J. Radiat. Biol. , vol.61 , pp. 737-748
    • Brenner, D.J.1    Ward, J.F.2
  • 15
    • 0034602643 scopus 로고    scopus 로고
    • Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation
    • Sutherland B.M., Bennett P.V., Sidorkina O., Laval J. Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:103-108.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 103-108
    • Sutherland, B.M.1    Bennett, P.V.2    Sidorkina, O.3    Laval, J.4
  • 16
    • 44349188585 scopus 로고    scopus 로고
    • Formation of clustered DNA damage after high-LET irradiation: a review
    • Hada M., Georgakilas A.G. Formation of clustered DNA damage after high-LET irradiation: a review. J. Radiat. Res. (Tokyo) 2008, 49:203-210.
    • (2008) J. Radiat. Res. (Tokyo) , vol.49 , pp. 203-210
    • Hada, M.1    Georgakilas, A.G.2
  • 18
    • 0035178567 scopus 로고    scopus 로고
    • Base excision repair processing of radiation-induced clustered DNA lesions
    • Blaisdell J.O., Harrison L., Wallace S.S. Base excision repair processing of radiation-induced clustered DNA lesions. Radiat. Prot. Dosim. 2001, 97:25-31.
    • (2001) Radiat. Prot. Dosim. , vol.97 , pp. 25-31
    • Blaisdell, J.O.1    Harrison, L.2    Wallace, S.S.3
  • 19
    • 0032519310 scopus 로고    scopus 로고
    • Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII
    • Harrison L., Hatahet Z., Purmal A.A., Wallace S.S. Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII. Nucleic Acids Res. 1998, 26:932-941.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 932-941
    • Harrison, L.1    Hatahet, Z.2    Purmal, A.A.3    Wallace, S.S.4
  • 20
    • 33846841032 scopus 로고    scopus 로고
    • Detection of oxidative clustered DNA lesions in X-irradiated mouse skin tissues and human MCF-7 breast cancer cells
    • Gollapalle E., Wang R., Adetolu R., Tsao D., Francisco D., Sigounas G., Georgakilas A.G. Detection of oxidative clustered DNA lesions in X-irradiated mouse skin tissues and human MCF-7 breast cancer cells. Radiat. Res. 2007, 167:207-216.
    • (2007) Radiat. Res. , vol.167 , pp. 207-216
    • Gollapalle, E.1    Wang, R.2    Adetolu, R.3    Tsao, D.4    Francisco, D.5    Sigounas, G.6    Georgakilas, A.G.7
  • 21
    • 0024195429 scopus 로고
    • DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability
    • Ward J.F. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. Prog. Nucleic Acid Res. Mol. Biol. 1988, 35:95-125.
    • (1988) Prog. Nucleic Acid Res. Mol. Biol. , vol.35 , pp. 95-125
    • Ward, J.F.1
  • 22
    • 34347368952 scopus 로고    scopus 로고
    • Energy deposition stochastics and track structure: what about the target?
    • Goodhead D.T. Energy deposition stochastics and track structure: what about the target?. Radiat. Prot. Dosim. 2006, 122:3-15.
    • (2006) Radiat. Prot. Dosim. , vol.122 , pp. 3-15
    • Goodhead, D.T.1
  • 23
  • 24
    • 0034753336 scopus 로고    scopus 로고
    • Computational approach for determining the spectrum of DNA damage induced by ionizing radiation
    • Nikjoo H., O'Neill P., Wilson W.E., Goodhead D.T. Computational approach for determining the spectrum of DNA damage induced by ionizing radiation. Radiat. Res. 2001, 156:577-583.
    • (2001) Radiat. Res. , vol.156 , pp. 577-583
    • Nikjoo, H.1    O'Neill, P.2    Wilson, W.E.3    Goodhead, D.T.4
  • 25
    • 0037080182 scopus 로고    scopus 로고
    • Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease
    • David-Cordonnier M.H., Cunniffe S.M., Hickson I.D., O'Neill P. Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease. Biochemistry 2002, 41:634-642.
    • (2002) Biochemistry , vol.41 , pp. 634-642
    • David-Cordonnier, M.H.1    Cunniffe, S.M.2    Hickson, I.D.3    O'Neill, P.4
  • 26
    • 0036682280 scopus 로고    scopus 로고
    • Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites
    • Gulston M., Fulford J., Jenner T., de Lara C., O'Neill P. Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites. Nucleic Acids Res. 2002, 30:3464-3472.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 3464-3472
    • Gulston, M.1    Fulford, J.2    Jenner, T.3    de Lara, C.4    O'Neill, P.5
  • 27
    • 11144272029 scopus 로고    scopus 로고
    • 8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1
    • Lomax M.E., Salje H., Cunniffe S., O'Neill P. 8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1. Radiat. Res. 2005, 163:79-84.
    • (2005) Radiat. Res. , vol.163 , pp. 79-84
    • Lomax, M.E.1    Salje, H.2    Cunniffe, S.3    O'Neill, P.4
  • 28
    • 2542637919 scopus 로고    scopus 로고
    • Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation
    • Gulston M., de Lara C., Jenner T., Davis E., O'Neill P. Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation. Nucleic Acids Res. 2004, 32:1602-1609.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1602-1609
    • Gulston, M.1    de Lara, C.2    Jenner, T.3    Davis, E.4    O'Neill, P.5
  • 29
    • 77950360354 scopus 로고    scopus 로고
    • Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage
    • Eccles L.J., Lomax M.E., O'Neill P. Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage. Nucleic Acids Res. 2010, 38:1123-1134.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 1123-1134
    • Eccles, L.J.1    Lomax, M.E.2    O'Neill, P.3
  • 30
    • 19644391375 scopus 로고    scopus 로고
    • Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site
    • Fujimoto H., Pinak M., Nemoto T., O'Neill P., Kume E., Saito K., Maekawa H. Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site. J. Comput. Chem. 2005, 26:788-798.
    • (2005) J. Comput. Chem. , vol.26 , pp. 788-798
    • Fujimoto, H.1    Pinak, M.2    Nemoto, T.3    O'Neill, P.4    Kume, E.5    Saito, K.6    Maekawa, H.7
  • 31
    • 0032788298 scopus 로고    scopus 로고
    • In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites
    • Harrison L., Hatahet Z., Wallace S.S. In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites. J. Mol. Biol. 1999, 290:667-684.
    • (1999) J. Mol. Biol. , vol.290 , pp. 667-684
    • Harrison, L.1    Hatahet, Z.2    Wallace, S.S.3
  • 32
    • 50849105384 scopus 로고    scopus 로고
    • DNA repair of clustered lesions in mammalian cells: involvement of non-homologous end-joining
    • Malyarchuk S., Castore R., Harrison L. DNA repair of clustered lesions in mammalian cells: involvement of non-homologous end-joining. Nucleic Acids Res. 2008, 36:4872-4882.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 4872-4882
    • Malyarchuk, S.1    Castore, R.2    Harrison, L.3
  • 33
    • 67949124717 scopus 로고    scopus 로고
    • Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic
    • Bellon S., Shikazono N., Cunniffe S., Lomax M., O'Neill P. Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic. Nucleic Acids Res. 2009, 37:4430-4440.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 4430-4440
    • Bellon, S.1    Shikazono, N.2    Cunniffe, S.3    Lomax, M.4    O'Neill, P.5
  • 35
    • 0027180956 scopus 로고
    • Effects of radiations of different qualities on cells: molecular mechanisms of damage and repair
    • Goodhead D.T., Thacker J., Cox R., Weiss, Lecture Effects of radiations of different qualities on cells: molecular mechanisms of damage and repair. Int. J. Radiat. Biol. 1993, 63:543-556.
    • (1993) Int. J. Radiat. Biol. , vol.63 , pp. 543-556
    • Goodhead, D.T.1    Thacker, J.2    Cox, R.3    Weiss, L.4
  • 36
    • 0034876617 scopus 로고    scopus 로고
    • Securing genome stability by orchestrating DNA repair: removal of radiation-induced clustered lesions in DNA
    • Dianov G.L., O'Neill P., Goodhead D.T. Securing genome stability by orchestrating DNA repair: removal of radiation-induced clustered lesions in DNA. Bioessays 2001, 23:745-749.
    • (2001) Bioessays , vol.23 , pp. 745-749
    • Dianov, G.L.1    O'Neill, P.2    Goodhead, D.T.3
  • 37
    • 0027172363 scopus 로고
    • DNA strand break induction and rejoining and cellular recovery in mammalian cells after heavy-ion irradiation
    • Heilmann J., Rink H., Taucher-Scholz G., Kraft G. DNA strand break induction and rejoining and cellular recovery in mammalian cells after heavy-ion irradiation. Radiat. Res. 1993, 135:46-55.
    • (1993) Radiat. Res. , vol.135 , pp. 46-55
    • Heilmann, J.1    Rink, H.2    Taucher-Scholz, G.3    Kraft, G.4
  • 38
    • 0029684225 scopus 로고    scopus 로고
    • Induction and rejoining of DNA double-strand breaks in CHO cells after heavy ion irradiation
    • Taucher-Scholz G., Heilmann J., Kraft G. Induction and rejoining of DNA double-strand breaks in CHO cells after heavy ion irradiation. Adv. Space Res. 1996, 18:83-92.
    • (1996) Adv. Space Res. , vol.18 , pp. 83-92
    • Taucher-Scholz, G.1    Heilmann, J.2    Kraft, G.3
  • 39
    • 0038301384 scopus 로고    scopus 로고
    • Biological imaging of heavy charged-particle tracks
    • Jakob B., Scholz M., Taucher-Scholz G. Biological imaging of heavy charged-particle tracks. Radiat. Res. 2003, 159:676-684.
    • (2003) Radiat. Res. , vol.159 , pp. 676-684
    • Jakob, B.1    Scholz, M.2    Taucher-Scholz, G.3
  • 40
    • 25444502873 scopus 로고    scopus 로고
    • Immunofluorescence detection of clustered gamma-H2AX foci induced by HZE-particle radiation
    • Desai N., Davis E., O'Neill P., Durante M., Cucinotta F.A., Wu H. Immunofluorescence detection of clustered gamma-H2AX foci induced by HZE-particle radiation. Radiat. Res. 2005, 164:518-522.
    • (2005) Radiat. Res. , vol.164 , pp. 518-522
    • Desai, N.1    Davis, E.2    O'Neill, P.3    Durante, M.4    Cucinotta, F.A.5    Wu, H.6
  • 41
    • 3042805315 scopus 로고    scopus 로고
    • Focus formation of DNA repair proteins in normal and repair-deficient cells irradiated with high-LET ions
    • Karlsson K.H., Stenerlow B. Focus formation of DNA repair proteins in normal and repair-deficient cells irradiated with high-LET ions. Radiat. Res. 2004, 161:517-527.
    • (2004) Radiat. Res. , vol.161 , pp. 517-527
    • Karlsson, K.H.1    Stenerlow, B.2
  • 42
    • 29644443959 scopus 로고    scopus 로고
    • Repair of DNA damage induced by accelerated heavy ions in mammalian cells proficient and deficient in the non-homologous end-joining pathway
    • Okayasu R., Okada M., Okabe A., Noguchi M., Takakura K., Takahashi S. Repair of DNA damage induced by accelerated heavy ions in mammalian cells proficient and deficient in the non-homologous end-joining pathway. Radiat. Res. 2006, 165:59-67.
    • (2006) Radiat. Res. , vol.165 , pp. 59-67
    • Okayasu, R.1    Okada, M.2    Okabe, A.3    Noguchi, M.4    Takakura, K.5    Takahashi, S.6
  • 44
    • 0345016976 scopus 로고    scopus 로고
    • Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis
    • Sutherland B.M., Georgakilas A.G., Bennett P.V., Laval J., Sutherland J.C. Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis. Mutat. Res. 2003, 531:93-107.
    • (2003) Mutat. Res. , vol.531 , pp. 93-107
    • Sutherland, B.M.1    Georgakilas, A.G.2    Bennett, P.V.3    Laval, J.4    Sutherland, J.C.5
  • 45
    • 0036639367 scopus 로고    scopus 로고
    • High efficiency detection of bi-stranded abasic clusters in gamma-irradiated DNA by putrescine
    • Georgakilas A.G., Bennett P.V., Sutherland B.M. High efficiency detection of bi-stranded abasic clusters in gamma-irradiated DNA by putrescine. Nucleic Acids Res. 2002, 30:2800-2808.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 2800-2808
    • Georgakilas, A.G.1    Bennett, P.V.2    Sutherland, B.M.3
  • 46
    • 6944248997 scopus 로고    scopus 로고
    • Processing of bistranded abasic DNA clusters in gamma-irradiated human hematopoietic cells
    • Georgakilas A.G., Bennett P.V., Wilson D.M., Sutherland B.M. Processing of bistranded abasic DNA clusters in gamma-irradiated human hematopoietic cells. Nucleic Acids Res. 2004, 32:5609-5620.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 5609-5620
    • Georgakilas, A.G.1    Bennett, P.V.2    Wilson, D.M.3    Sutherland, B.M.4
  • 48
    • 0035912756 scopus 로고    scopus 로고
    • Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
    • Blaisdell J.O., Wallace S.S. Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:7426-7430.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 7426-7430
    • Blaisdell, J.O.1    Wallace, S.S.2
  • 49
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou E.P., Boon C., Redon C., Bonner W.M. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 1999, 146:905-916.
    • (1999) J. Cell Biol. , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 51
    • 0034739853 scopus 로고    scopus 로고
    • P53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
    • Schultz L.B., Chehab N.H., Malikzay A., Halazonetis T.D. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J. Cell Biol. 2000, 151:1381-1390.
    • (2000) J. Cell Biol. , vol.151 , pp. 1381-1390
    • Schultz, L.B.1    Chehab, N.H.2    Malikzay, A.3    Halazonetis, T.D.4
  • 52
    • 67651162117 scopus 로고    scopus 로고
    • Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation
    • Asaithamby A., Chen D.J. Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation. Nucleic Acids Res. 2009, 37:3912-3923.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 3912-3923
    • Asaithamby, A.1    Chen, D.J.2
  • 53
    • 0034693220 scopus 로고    scopus 로고
    • Cellular responses and repair of single-strand breaks introduced by UV damage endonuclease in mammalian cells
    • Okano S., Kanno S., Nakajima S., Yasui A. Cellular responses and repair of single-strand breaks introduced by UV damage endonuclease in mammalian cells. J. Biol. Chem. 2000, 275:32635-32641.
    • (2000) J. Biol. Chem. , vol.275 , pp. 32635-32641
    • Okano, S.1    Kanno, S.2    Nakajima, S.3    Yasui, A.4
  • 55
  • 57
    • 33846782890 scopus 로고    scopus 로고
    • UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles
    • Campalans A., Amouroux R., Bravard A., Epe B., Radicella J.P. UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles. J. Cell Sci. 2007, 120:23-32.
    • (2007) J. Cell Sci. , vol.120 , pp. 23-32
    • Campalans, A.1    Amouroux, R.2    Bravard, A.3    Epe, B.4    Radicella, J.P.5
  • 58
    • 77955640606 scopus 로고    scopus 로고
    • Fluorescent proteins and their applications in imaging living cells and tissues
    • Chudakov D.M., Matz M.V., Lukyanov S., Lukyanov K.A. Fluorescent proteins and their applications in imaging living cells and tissues. Physiol. Rev. 2010, 90:1103-1163.
    • (2010) Physiol. Rev. , vol.90 , pp. 1103-1163
    • Chudakov, D.M.1    Matz, M.V.2    Lukyanov, S.3    Lukyanov, K.A.4
  • 60
    • 19544376983 scopus 로고    scopus 로고
    • Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy
    • Jakob B., Rudolph J.H., Gueven N., Lavin M.F., Taucher-Scholz G. Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy. Radiat. Res. 2005, 163:681-690.
    • (2005) Radiat. Res. , vol.163 , pp. 681-690
    • Jakob, B.1    Rudolph, J.H.2    Gueven, N.3    Lavin, M.F.4    Taucher-Scholz, G.5
  • 62
    • 77952095382 scopus 로고    scopus 로고
    • Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization
    • Costes S.V., Chiolo I., Pluth J.M., Barcellos-Hoff M.H., Jakob B. Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization. Mutat. Res. 2010, 704:78-87.
    • (2010) Mutat. Res. , vol.704 , pp. 78-87
    • Costes, S.V.1    Chiolo, I.2    Pluth, J.M.3    Barcellos-Hoff, M.H.4    Jakob, B.5
  • 64
    • 47349107760 scopus 로고    scopus 로고
    • ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
    • Goodarzi A.A., Noon A.T., Deckbar D., Ziv Y., Shiloh Y., Lobrich M., Jeggo P.A. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell 2008, 31:167-177.
    • (2008) Mol. Cell , vol.31 , pp. 167-177
    • Goodarzi, A.A.1    Noon, A.T.2    Deckbar, D.3    Ziv, Y.4    Shiloh, Y.5    Lobrich, M.6    Jeggo, P.A.7
  • 66
    • 77952089468 scopus 로고    scopus 로고
    • Spatiotemporal analysis of DNA repair using charged particle radiation
    • Tobias F., Durante M., Taucher-Scholz G., Jakob B. Spatiotemporal analysis of DNA repair using charged particle radiation. Mutat. Res. 2010, 704:54-60.
    • (2010) Mutat. Res. , vol.704 , pp. 54-60
    • Tobias, F.1    Durante, M.2    Taucher-Scholz, G.3    Jakob, B.4
  • 67
    • 33846230598 scopus 로고    scopus 로고
    • Homology-directed repair is required for the development of radioresistance during S phase: interplay between double-strand break repair and checkpoint response
    • Tamulevicius P., Wang M., Iliakis G. Homology-directed repair is required for the development of radioresistance during S phase: interplay between double-strand break repair and checkpoint response. Radiat. Res. 2007, 167:1-11.
    • (2007) Radiat. Res. , vol.167 , pp. 1-11
    • Tamulevicius, P.1    Wang, M.2    Iliakis, G.3
  • 68
    • 77649131406 scopus 로고    scopus 로고
    • Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
    • Moynahan M.E., Jasin M. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat. Rev. Mol. Cell Biol. 2010, 11:196-207.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 196-207
    • Moynahan, M.E.1    Jasin, M.2
  • 69
    • 0034951142 scopus 로고    scopus 로고
    • Double-strand-break-induced homologous recombination in mammalian cells
    • Johnson R.D., Jasin M. Double-strand-break-induced homologous recombination in mammalian cells. Biochem. Soc. Trans. 2001, 29:196-201.
    • (2001) Biochem. Soc. Trans. , vol.29 , pp. 196-201
    • Johnson, R.D.1    Jasin, M.2
  • 70
    • 33846684170 scopus 로고    scopus 로고
    • Molecular mechanisms of sister-chromatid exchange
    • Wilson D.M., Thompson L.H. Molecular mechanisms of sister-chromatid exchange. Mutat. Res. 2007, 616:11-23.
    • (2007) Mutat. Res. , vol.616 , pp. 11-23
    • Wilson, D.M.1    Thompson, L.H.2
  • 71
    • 77953229115 scopus 로고    scopus 로고
    • The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
    • Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 2010, 79:181-211.
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 181-211
    • Lieber, M.R.1
  • 72
    • 0042632901 scopus 로고    scopus 로고
    • Pathways of DNA double-strand break repair during the mammalian cell cycle
    • Rothkamm K., Kruger I., Thompson L.H., Lobrich M. Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol. Cell. Biol. 2003, 23:5706-5715.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5706-5715
    • Rothkamm, K.1    Kruger, I.2    Thompson, L.H.3    Lobrich, M.4
  • 73
    • 0025853166 scopus 로고
    • Response of X-ray-sensitive CHO mutant cells (xrs-6c) to radiation. II. Relationship between cell survival and the induction of chromosomal damage with low doses of alpha particles
    • Nagasawa H., Little J.B., Inkret W.C., Carpenter S., Raju M.R., Chen D.J., Strniste G.F. Response of X-ray-sensitive CHO mutant cells (xrs-6c) to radiation. II. Relationship between cell survival and the induction of chromosomal damage with low doses of alpha particles. Radiat. Res. 1991, 126:280-288.
    • (1991) Radiat. Res. , vol.126 , pp. 280-288
    • Nagasawa, H.1    Little, J.B.2    Inkret, W.C.3    Carpenter, S.4    Raju, M.R.5    Chen, D.J.6    Strniste, G.F.7
  • 74
    • 20644450114 scopus 로고    scopus 로고
    • Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells
    • Hinz J.M., Yamada N.A., Salazar E.P., Tebbs R.S., Thompson L.H. Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells. DNA Repair (Amst.) 2005, 4:782-792.
    • (2005) DNA Repair (Amst.) , vol.4 , pp. 782-792
    • Hinz, J.M.1    Yamada, N.A.2    Salazar, E.P.3    Tebbs, R.S.4    Thompson, L.H.5
  • 75
    • 3042577121 scopus 로고    scopus 로고
    • Persistence of chromosome aberrations in mice acutely exposed to 56Fe+26 ions
    • Tucker J.D., Marples B., Ramsey M.J., Lutze-Mann L.H. Persistence of chromosome aberrations in mice acutely exposed to 56Fe+26 ions. Radiat. Res. 2004, 161:648-655.
    • (2004) Radiat. Res. , vol.161 , pp. 648-655
    • Tucker, J.D.1    Marples, B.2    Ramsey, M.J.3    Lutze-Mann, L.H.4
  • 76
    • 42249098075 scopus 로고    scopus 로고
    • The Ku-dependent non-homologous end-joining but not other repair pathway is inhibited by high linear energy transfer ionizing radiation
    • Wang H., Wang X., Zhang P., Wang Y. The Ku-dependent non-homologous end-joining but not other repair pathway is inhibited by high linear energy transfer ionizing radiation. DNA Repair (Amst.) 2008, 7:725-733.
    • (2008) DNA Repair (Amst.) , vol.7 , pp. 725-733
    • Wang, H.1    Wang, X.2    Zhang, P.3    Wang, Y.4
  • 77
    • 77953716710 scopus 로고    scopus 로고
    • Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation
    • Wang H., Zhang X., Wang P., Yu X., Essers J., Chen D., Kanaar R., Takeda S., Wang Y. Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation. Nucleic Acids Res. 2010, 38:3245-3251.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 3245-3251
    • Wang, H.1    Zhang, X.2    Wang, P.3    Yu, X.4    Essers, J.5    Chen, D.6    Kanaar, R.7    Takeda, S.8    Wang, Y.9
  • 78
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Paques F., Haber J.E. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 1999, 63:349-404.
    • (1999) Microbiol. Mol. Biol. Rev. , vol.63 , pp. 349-404
    • Paques, F.1    Haber, J.E.2
  • 79
    • 0035695023 scopus 로고    scopus 로고
    • Recombination at double-strand breaks and DNA ends: conserved mechanisms from phage to humans
    • Cromie G.A., Connelly J.C., Leach D.R. Recombination at double-strand breaks and DNA ends: conserved mechanisms from phage to humans. Mol. Cell 2001, 8:1163-1174.
    • (2001) Mol. Cell , vol.8 , pp. 1163-1174
    • Cromie, G.A.1    Connelly, J.C.2    Leach, D.R.3
  • 82
    • 77955841149 scopus 로고    scopus 로고
    • Collaboration and competition between DNA double-strand break repair pathways
    • Kass E.M., Jasin M. Collaboration and competition between DNA double-strand break repair pathways. FEBS Lett. 2010, 584:3703-3708.
    • (2010) FEBS Lett. , vol.584 , pp. 3703-3708
    • Kass, E.M.1    Jasin, M.2
  • 83
    • 38049155945 scopus 로고    scopus 로고
    • Regulation of DNA double-strand break repair pathway choice
    • Shrivastav M., De Haro L.P., Nickoloff J.A. Regulation of DNA double-strand break repair pathway choice. Cell Res. 2008, 18:134-147.
    • (2008) Cell Res. , vol.18 , pp. 134-147
    • Shrivastav, M.1    De Haro, L.P.2    Nickoloff, J.A.3
  • 84
    • 77954313601 scopus 로고    scopus 로고
    • DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints
    • You Z., Bailis J.M. DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints. Trends Cell Biol. 2010, 20:402-409.
    • (2010) Trends Cell Biol. , vol.20 , pp. 402-409
    • You, Z.1    Bailis, J.M.2
  • 85
    • 0037133699 scopus 로고    scopus 로고
    • DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination
    • Allen C., Kurimasa A., Brenneman M.A., Chen D.J., Nickoloff J.A. DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:3758-3763.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 3758-3763
    • Allen, C.1    Kurimasa, A.2    Brenneman, M.A.3    Chen, D.J.4    Nickoloff, J.A.5
  • 86
    • 0035893363 scopus 로고    scopus 로고
    • End-binding protein modulates homologous repair of double-strand breaks in mammalian cells
    • Pierce A.J., Hu P., Han M., Ellis N., Jasin M., Ku D.N.A. end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev. 2001, 15:3237-3242.
    • (2001) Genes Dev. , vol.15 , pp. 3237-3242
    • Pierce, A.J.1    Hu, P.2    Han, M.3    Ellis, N.4    Jasin, M.5    Ku, D.N.A.6
  • 87
    • 2642511410 scopus 로고    scopus 로고
    • Induction of homologous recombination in the hprt gene of V79 Chinese hamster cells in response to low- and high-LET irradiation
    • Olsson G., Czene S., Jenssen D., Harms-Ringdahl M. Induction of homologous recombination in the hprt gene of V79 Chinese hamster cells in response to low- and high-LET irradiation. Cytogenet. Genome Res. 2004, 104:227-231.
    • (2004) Cytogenet. Genome Res. , vol.104 , pp. 227-231
    • Olsson, G.1    Czene, S.2    Jenssen, D.3    Harms-Ringdahl, M.4
  • 88
    • 73349132033 scopus 로고    scopus 로고
    • Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions
    • Zafar F., Seidler S.B., Kronenberg A., Schild D., Wiese C. Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions. Radiat. Res. 2010, 173:27-39.
    • (2010) Radiat. Res. , vol.173 , pp. 27-39
    • Zafar, F.1    Seidler, S.B.2    Kronenberg, A.3    Schild, D.4    Wiese, C.5
  • 89
    • 0037314536 scopus 로고    scopus 로고
    • Repair of radiation-induced DNA double-strand breaks is dependent upon radiation quality and the structural complexity of double-strand breaks
    • Pastwa E., Neumann R.D., Mezhevaya K., Winters T.A. Repair of radiation-induced DNA double-strand breaks is dependent upon radiation quality and the structural complexity of double-strand breaks. Radiat. Res. 2003, 159:251-261.
    • (2003) Radiat. Res. , vol.159 , pp. 251-261
    • Pastwa, E.1    Neumann, R.D.2    Mezhevaya, K.3    Winters, T.A.4
  • 90
    • 0030743386 scopus 로고    scopus 로고
    • Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
    • Grawunder U., Wilm M., Wu X., Kulesza P., Wilson T.E., Mann M., Lieber M.R. Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature 1997, 388:492-495.
    • (1997) Nature , vol.388 , pp. 492-495
    • Grawunder, U.1    Wilm, M.2    Wu, X.3    Kulesza, P.4    Wilson, T.E.5    Mann, M.6    Lieber, M.R.7
  • 91
    • 0037115920 scopus 로고    scopus 로고
    • Structure and function of nucleases in DNA repair: shape, grip and blade of the DNA scissors
    • Nishino T., Morikawa K. Structure and function of nucleases in DNA repair: shape, grip and blade of the DNA scissors. Oncogene 2002, 21:9022-9032.
    • (2002) Oncogene , vol.21 , pp. 9022-9032
    • Nishino, T.1    Morikawa, K.2
  • 92
    • 0030691121 scopus 로고    scopus 로고
    • Hierarchical deterioration of body systems in Werner's syndrome: implications for normal ageing
    • Goto M. Hierarchical deterioration of body systems in Werner's syndrome: implications for normal ageing. Mech. Ageing Dev. 1997, 98:239-254.
    • (1997) Mech. Ageing Dev. , vol.98 , pp. 239-254
    • Goto, M.1
  • 93
    • 76749168005 scopus 로고    scopus 로고
    • Roles of Werner syndrome protein in protection of genome integrity
    • Rossi M.L., Ghosh A.K., Bohr V.A. Roles of Werner syndrome protein in protection of genome integrity. DNA Repair (Amst.) 2010, 9:331-344.
    • (2010) DNA Repair (Amst.) , vol.9 , pp. 331-344
    • Rossi, M.L.1    Ghosh, A.K.2    Bohr, V.A.3
  • 94
    • 0031686571 scopus 로고    scopus 로고
    • The premature ageing syndrome protein, WRN, is a 3′->5′ exonuclease
    • Huang S., Li B., Gray M.D., Oshima J., Mian I.S., Campisi J. The premature ageing syndrome protein, WRN, is a 3′->5′ exonuclease. Nat. Genet. 1998, 20:114-116.
    • (1998) Nat. Genet. , vol.20 , pp. 114-116
    • Huang, S.1    Li, B.2    Gray, M.D.3    Oshima, J.4    Mian, I.S.5    Campisi, J.6
  • 95
    • 0347362703 scopus 로고    scopus 로고
    • Werner syndrome protein contains three structure-specific DNA binding domains
    • von Kobbe C., Thoma N.H., Czyzewski B.K., Pavletich N.P., Bohr V.A. Werner syndrome protein contains three structure-specific DNA binding domains. J. Biol. Chem. 2003, 278:52997-53006.
    • (2003) J. Biol. Chem. , vol.278 , pp. 52997-53006
    • von Kobbe, C.1    Thoma, N.H.2    Czyzewski, B.K.3    Pavletich, N.P.4    Bohr, V.A.5
  • 96
    • 42049116919 scopus 로고    scopus 로고
    • The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest
    • Sidorova J.M., Li N., Folch A., Monnat R.J. The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest. Cell Cycle 2008, 7:796-807.
    • (2008) Cell Cycle , vol.7 , pp. 796-807
    • Sidorova, J.M.1    Li, N.2    Folch, A.3    Monnat, R.J.4
  • 97
    • 77955480303 scopus 로고    scopus 로고
    • Identification of a coiled coil in Werner syndrome protein that facilitates multimerization and promotes exonuclease processivity
    • Perry J.J., Asaithamby A., Barnebey A., Kiamanesch F., Chen D.J., Han S., Tainer J.A., Yannone S.M. Identification of a coiled coil in Werner syndrome protein that facilitates multimerization and promotes exonuclease processivity. J. Biol. Chem. 2010, 285:25699-25707.
    • (2010) J. Biol. Chem. , vol.285 , pp. 25699-25707
    • Perry, J.J.1    Asaithamby, A.2    Barnebey, A.3    Kiamanesch, F.4    Chen, D.J.5    Han, S.6    Tainer, J.A.7    Yannone, S.M.8
  • 98
    • 62849091779 scopus 로고    scopus 로고
    • The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation
    • Opresko P.L., Sowd G., Wang H. The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation. PLoS One 2009, 4:e4825.
    • (2009) PLoS One , vol.4
    • Opresko, P.L.1    Sowd, G.2    Wang, H.3
  • 100
    • 0037166306 scopus 로고    scopus 로고
    • Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation
    • Karmakar P., Piotrowski J., Brosh R.M., Sommers J.A., Miller S.P., Cheng W.H., Snowden C.M., Ramsden D.A., Bohr V.A. Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation. J. Biol. Chem. 2002, 277:18291-18302.
    • (2002) J. Biol. Chem. , vol.277 , pp. 18291-18302
    • Karmakar, P.1    Piotrowski, J.2    Brosh, R.M.3    Sommers, J.A.4    Miller, S.P.5    Cheng, W.H.6    Snowden, C.M.7    Ramsden, D.A.8    Bohr, V.A.9
  • 101
    • 0035851181 scopus 로고    scopus 로고
    • Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase
    • Yannone S.M., Roy S., Chan D.W., Murphy M.B., Huang S., Campisi J., Chen D.J. Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase. J. Biol. Chem. 2001, 276:38242-38248.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38242-38248
    • Yannone, S.M.1    Roy, S.2    Chan, D.W.3    Murphy, M.B.4    Huang, S.5    Campisi, J.6    Chen, D.J.7
  • 102
    • 0035009356 scopus 로고    scopus 로고
    • Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51
    • Sakamoto S., Nishikawa K., Heo S.J., Goto M., Furuichi Y., Shimamoto A. Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51. Genes Cells 2001, 6:421-430.
    • (2001) Genes Cells , vol.6 , pp. 421-430
    • Sakamoto, S.1    Nishikawa, K.2    Heo, S.J.3    Goto, M.4    Furuichi, Y.5    Shimamoto, A.6
  • 104
    • 0141480945 scopus 로고    scopus 로고
    • WRN interacts physically and functionally with the recombination mediator protein RAD52
    • Baynton K., Otterlei M., Bjoras M., von Kobbe C., Bohr V.A., Seeberg E. WRN interacts physically and functionally with the recombination mediator protein RAD52. J. Biol. Chem. 2003, 278:36476-36486.
    • (2003) J. Biol. Chem. , vol.278 , pp. 36476-36486
    • Baynton, K.1    Otterlei, M.2    Bjoras, M.3    von Kobbe, C.4    Bohr, V.A.5    Seeberg, E.6
  • 105
    • 33846141125 scopus 로고    scopus 로고
    • Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest
    • Otterlei M., Bruheim P., Ahn B., Bussen W., Karmakar P., Baynton K., Bohr V.A. Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest. J. Cell Sci. 2006, 119:5137-5146.
    • (2006) J. Cell Sci. , vol.119 , pp. 5137-5146
    • Otterlei, M.1    Bruheim, P.2    Ahn, B.3    Bussen, W.4    Karmakar, P.5    Baynton, K.6    Bohr, V.A.7
  • 107
    • 1842685207 scopus 로고    scopus 로고
    • The Werner syndrome protein has separable recombination and survival functions
    • Swanson C., Saintigny Y., Emond M.J., Monnat R.J. The Werner syndrome protein has separable recombination and survival functions. DNA Repair (Amst.) 2004, 3:475-482.
    • (2004) DNA Repair (Amst.) , vol.3 , pp. 475-482
    • Swanson, C.1    Saintigny, Y.2    Emond, M.J.3    Monnat, R.J.4
  • 108
    • 0034231844 scopus 로고    scopus 로고
    • Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest
    • Constantinou A., Tarsounas M., Karow J.K., Brosh R.M., Bohr V.A., Hickson I.D., West S.C. Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. EMBO Rep. 2000, 1:80-84.
    • (2000) EMBO Rep. , vol.1 , pp. 80-84
    • Constantinou, A.1    Tarsounas, M.2    Karow, J.K.3    Brosh, R.M.4    Bohr, V.A.5    Hickson, I.D.6    West, S.C.7
  • 109
    • 77956881105 scopus 로고    scopus 로고
    • ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery
    • Ammazzalorso F., Pirzio L.M., Bignami M., Franchitto A., Pichierri P. ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery. Embo J. 2010.
    • (2010) Embo J.
    • Ammazzalorso, F.1    Pirzio, L.M.2    Bignami, M.3    Franchitto, A.4    Pichierri, P.5
  • 112
    • 0037565312 scopus 로고    scopus 로고
    • The V(D)J recombination/DNA repair factor artemis belongs to the metallo-beta-lactamase family and constitutes a critical developmental checkpoint of the lymphoid system
    • Moshous D., Callebaut I., de Chasseval R., Poinsignon C., Villey I., Fischer A., de Villartay J.P. The V(D)J recombination/DNA repair factor artemis belongs to the metallo-beta-lactamase family and constitutes a critical developmental checkpoint of the lymphoid system. Ann. N. Y. Acad. Sci. 2003, 987:150-157.
    • (2003) Ann. N. Y. Acad. Sci. , vol.987 , pp. 150-157
    • Moshous, D.1    Callebaut, I.2    de Chasseval, R.3    Poinsignon, C.4    Villey, I.5    Fischer, A.6    de Villartay, J.P.7
  • 113
    • 70349574621 scopus 로고    scopus 로고
    • V(D)J recombination deficiencies
    • de Villartay J.P. V(D)J recombination deficiencies. Adv. Exp. Med. Biol. 2009, 650:46-58.
    • (2009) Adv. Exp. Med. Biol. , vol.650 , pp. 46-58
    • de Villartay, J.P.1
  • 114
    • 77958548176 scopus 로고    scopus 로고
    • Functions and regulation of artemis: a goddess in the maintenance of genome integrity
    • Kurosawa A., Adachi N. Functions and regulation of artemis: a goddess in the maintenance of genome integrity. J. Radiat. Res. (Tokyo) 2010.
    • (2010) J. Radiat. Res. (Tokyo)
    • Kurosawa, A.1    Adachi, N.2
  • 116
    • 20644463916 scopus 로고    scopus 로고
    • The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps
    • Ma Y., Schwarz K., Lieber M.R. The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps. DNA Repair (Amst.) 2005, 4:845-851.
    • (2005) DNA Repair (Amst.) , vol.4 , pp. 845-851
    • Ma, Y.1    Schwarz, K.2    Lieber, M.R.3
  • 118
    • 59849089955 scopus 로고    scopus 로고
    • Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
    • Mahaney B.L., Meek K., Lees-Miller S.P. Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem. J. 2009, 417:639-650.
    • (2009) Biochem. J. , vol.417 , pp. 639-650
    • Mahaney, B.L.1    Meek, K.2    Lees-Miller, S.P.3
  • 119
    • 3142555854 scopus 로고    scopus 로고
    • Functional and biochemical dissection of the structure-specific nuclease ARTEMIS
    • Pannicke U., Ma Y., Hopfner K.P., Niewolik D., Lieber M.R., Schwarz K. Functional and biochemical dissection of the structure-specific nuclease ARTEMIS. Embo J. 2004, 23:1987-1997.
    • (2004) Embo J. , vol.23 , pp. 1987-1997
    • Pannicke, U.1    Ma, Y.2    Hopfner, K.P.3    Niewolik, D.4    Lieber, M.R.5    Schwarz, K.6
  • 120
    • 33646090620 scopus 로고    scopus 로고
    • Artemis phosphorylated by DNA-dependent protein kinase associates preferentially with discrete regions of chromatin
    • Soubeyrand S., Pope L., De Chasseval R., Gosselin D., Dong F., de Villartay J.P., Hache R.J. Artemis phosphorylated by DNA-dependent protein kinase associates preferentially with discrete regions of chromatin. J. Mol. Biol. 2006, 358:1200-1211.
    • (2006) J. Mol. Biol. , vol.358 , pp. 1200-1211
    • Soubeyrand, S.1    Pope, L.2    De Chasseval, R.3    Gosselin, D.4    Dong, F.5    de Villartay, J.P.6    Hache, R.J.7
  • 121
    • 16244401671 scopus 로고    scopus 로고
    • Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression
    • Wang J., Pluth J.M., Cooper P.K., Cowan M.J., Chen D.J., Yannone S.M. Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression. DNA Repair (Amst.) 2005, 4:556-570.
    • (2005) DNA Repair (Amst.) , vol.4 , pp. 556-570
    • Wang, J.1    Pluth, J.M.2    Cooper, P.K.3    Cowan, M.J.4    Chen, D.J.5    Yannone, S.M.6
  • 123
    • 25444475799 scopus 로고    scopus 로고
    • Repair of double-strand DNA breaks by the human nonhomologous DNA end joining pathway: the iterative processing model
    • Ma Y., Lu H., Schwarz K., Lieber M.R. Repair of double-strand DNA breaks by the human nonhomologous DNA end joining pathway: the iterative processing model. Cell Cycle 2005, 4:1193-1200.
    • (2005) Cell Cycle , vol.4 , pp. 1193-1200
    • Ma, Y.1    Lu, H.2    Schwarz, K.3    Lieber, M.R.4
  • 124
    • 34047153762 scopus 로고    scopus 로고
    • Functions and regulation of human artemis in double strand break repair
    • Dahm K. Functions and regulation of human artemis in double strand break repair. J. Cell. Biochem. 2007, 100:1346-1351.
    • (2007) J. Cell. Biochem. , vol.100 , pp. 1346-1351
    • Dahm, K.1
  • 126
    • 77952866393 scopus 로고    scopus 로고
    • More modifiers move on DNA damage
    • Morris J.R. More modifiers move on DNA damage. Cancer Res. 2010, 70:3861-3863.
    • (2010) Cancer Res. , vol.70 , pp. 3861-3863
    • Morris, J.R.1
  • 128
    • 67849119704 scopus 로고    scopus 로고
    • Comparison of several radiation effects in human MCF10A mammary epithelial cells cultured as 2D monolayers or 3D acinar stuctures in matrigel
    • Lin Y.F., Nagasawa H., Peng Y., Chuang E.Y., Bedford J.S. Comparison of several radiation effects in human MCF10A mammary epithelial cells cultured as 2D monolayers or 3D acinar stuctures in matrigel. Radiat. Res. 2009, 171:708-715.
    • (2009) Radiat. Res. , vol.171 , pp. 708-715
    • Lin, Y.F.1    Nagasawa, H.2    Peng, Y.3    Chuang, E.Y.4    Bedford, J.S.5
  • 129
    • 58349101767 scopus 로고    scopus 로고
    • Two- and three-dimensional models for risk assessment of radiation-enhanced colorectal tumorigenesis
    • Roig A.I., Hight S.K., Shay J.W. Two- and three-dimensional models for risk assessment of radiation-enhanced colorectal tumorigenesis. Radiat. Res. 2009, 171:33-40.
    • (2009) Radiat. Res. , vol.171 , pp. 33-40
    • Roig, A.I.1    Hight, S.K.2    Shay, J.W.3
  • 130


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