Clusters of DNA damage induced by ionizing radiation: Formation of short DNA fragments. II. Experimental detection

Radiation Research

Volumn 145, Issue 2, 1996, Pages 200-209

  Rydberg, Björn ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DNA DAMAGE; DNA DETERMINATION; DNA STRAND BREAKAGE; FIBROBLAST; IONIZING RADIATION; MODEL; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

NASA DISCIPLINE NUMBER 93-10; NASA DISCIPLINE RADIATION HEALTH; NASA PROGRAM NSCORT; NON-NASA CENTER;

CELLS, CULTURED; CHROMATIN; DNA; DNA DAMAGE; DNA REPAIR; DNA, SINGLE-STRANDED; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; IRON; LINEAR ENERGY TRANSFER; NITROGEN; RADIATION, IONIZING; X-RAYS;

EID: 0030023098     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579175     Document Type: Article

References (34)

1. A. Mozumder and J. L. Magee, Model of tracks of ionizing radiations for radical reaction mechanisms. Radiat. Res. 28, 203-214 (1966).
2. 2 of DNA and interphase chromosome damage in plateau-phase Chinese hamster ovary cells. Radiat Res. 131, 192-203 (1992).
3. D. T. Goodhead, J. Thacker and R. Cox, Effects of radiations of different qualities on cells: molecular mechanisms of damage and repair. Int. J. Radiat. Biol 63, 543-556 (1993).
4. A. M. Kellerer and H. H. Rossi, The theory of dual radiation action. Curr. Top. Radiat. Res. Q. 8, 85-158 (1972).
5. J. F. Ward, Biochemistry of DNA lesions. Radiat. Res. 104, S-103-S-111 (1985).
6. W. R. Holley and A. Chatterjee, Clusters of DNA damage induced by ionizing radiation: Formation of short DNA fragments. I Theoretical modeling Radiat Res. 145, 188-199 (1996).
7. J Widom, Toward a unified model of chromatin folding. Annu. Rev. Biophys. Biophys. Chem. 18, 365-395 (1989).
8. R. A. Horowitz, D. A. Agard, J. W. Sedat and C. L. Woodcock, The three-dimensional architecture of chromatin in situ: electron tomography reveals fibers composed of a continuously variable zig-zag nucleosomal ribbon. J. Cell. Biol. 125, 1-10 (1994).
9. J. W. Bodnar, A domain model for eukaryotic DNA organization: A molecular basis for cell differentiation and chromosome evolution. J. Theor. Biol. 132, 479-507 (1988).
10. B. Rydberg, M. Löbrich and P. K. Cooper. DNA double-strand breaks induced by high-energy neon and iron ions in human fibroblasts. I. Pulsed-field gel electrophoresis method. Radiat. Res. 139, 133-141 (1994).
11. E. A. Blakely, C. A. Tobias, T. C. H. Yang, K. C. Smith and J. T. Lyman, Inactivation of human kidney cells by high-energy monoenergetic heavy-ion beams. Radiat. Res. 80, 122-160 (1979).
12. J. Sambrook, E. F. Frisch and T. Maniatis, Molecular Cloning, A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989.
13. B Cedervall and P. Källman, Randomly distributed DNA double-strand breaks as measured by pulsed field gel electrophoresis: a series of explanatory calculations. Radiat. Environ. Biophys. 33, 9-21 (1994).
14. M. Löbrich, B. Rydberg and P. K. Cooper, DNA double-strand breaks induced by high-energy neon and iron ions in human fibroblasts. II. Probing individual NotI fragments by hybridization. Radiat. Res. 139, 142-151 (1994).
15. A. R. Lehmann and M. G. Ormerod, The replication of DNA in murine lymphoma cells (L5178Y). I. Rate of replication. Biochim. Biophys Acta 204, 128-143 (1970).
16. R. B. Setlow and J. K. Setlow, Effects of radiation on polynucleotides. Annu. Rev. Biophys. Bioeng. 1, 293-346 (1972).
17. T. M. Kovai, R. W. Hart, W. C. Myser and W. F. Hink, DNA single-strand break repair in cultured insect and mammalian cells after X-irradiation. Int. J. Radiat. Biol. 35, 183-188 (1979).
18. F. Hutchinson, Chemical changes induced in DNA by ionizing radiation. Prog. Nucleic Acid Res. Mol. Biol. 32, 115-154 (1985).
19. 60Co γ-irradiated human cell lines. Radiat. Res. 114, 168-185 (1988).
20. J. W. Gaubatz, Extrachromosomal circular DNAs and genomic sequence plasticity in eukaryotic cells. Mutat. Res. 237, 271-292 (1990).
21. D T. Goodhead and H. Nikjoo, Track structure analysis of ultrasoft X-rays compared to high- and low-LET radiations. Int. J. Radiat. Biol. 55, 513-529 (1989).
22. D. T. Goodhead, Initial events in the cellular effects of ionizing radiations: clustered damage in DNA. Int. J. Radiat. Biol. 65, 7-17 (1994).
23. V. Michalik, Distance distributions for energy deposition clusters in different particle tracks. Radiat. Prot. Dosim. 52, 245-248 (1994).
24. V. Michalik, Estimation of double-strand break quality based on track-structure calculations. Radiat. Environ. Biophys. 32, 251-258 (1993).
25. R. S. Malyapa, W. D. Wright and J. L. Roti Roti, Radiation sensitivity correlates with changes in DNA supercoiling and nucleoid protein content in cells of three Chinese hamster cell lines. Radiat. Res. 140, 312-320 (1994).
26. A. Chatterjee and W. R. Holley, Energy deposition mechanisms and biochemical aspects of DNA strand breaks by ionizing radiation. Int. J. Quant. Chem. 39, 709-727 (1991).
27. B. Rydberg, DNA strand breaks induced by low-energy heavy ions. Int. J. Radiat. Biol. 47, 57-61 (1985).
28. E. Aufderheide, H. Rink, L. Hieber and G. Kraft, Heavy ion effects on cellular DNA: strand break induction and repair in cultured diploid lens epithelial cells. Int. J. Radiat. Biol. 51, 779-790 (1987).
29. G. Ahnstrom and K-A. Edvardsson, Radiation-induced single-strand breaks in DNA determined by rate of alkaline strand separation and hydroxylapatite chromatography: an alternative to velocity sedimentation. Int J. Radiat. Biol. 26, 493-497 (1974).
30. M. A. Ritter, J. E. Cleaver and C. A. Tobias, High-LET radiations induce a large proportion of non-rejoining DNA breaks. Nature 266, 653-655 (1977).
31. R. Roots, T. C. H. Yang, L. Craise, E. A. Blakely and C. A. Tobias, Impaired repair capacity of DNA breaks induced in mammalian cellular DNA by accelerated heavy ions. Radiat. Res. 78, 38-49 (1979).
32. G. P. van der Schans, M. C. Paterson and W. G. Cross, DNA strand break and rejoining in cultured human fibroblasts exposed to fast neutrons or gamma rays. Int. J. Radiat. Biol. 44, 75-85 (1983).
33. D. Blocher, DNA double-strand break repair determines the RBE of α-particles. Int. J. Radiat. Biol. 54, 761-771 (1988).
34. M. J. Peak, L. Wang, C. K. Hill and J. G. Peak, Comparison of repair of DNA double-strand breaks caused by neutron or gamma radiation in cultured human cells. Int. J. Radiat. Biol. 60, 891-898 (1991).