Nucleosomes suppress the formation of double-strand DNA breaks during attempted base excision repair of clustered oxidative damages

Journal of Biological Chemistry

Volumn 289, Issue 29, 2014, Pages 19881-19893

  Cannan, Wendy J ^a   Tsang, Betty P ^a   Wallace, Susan S ^a   Pederson, David S ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IONIZING RADIATION; REPAIR;

BASE EXCISION REPAIRS; DNA GLYCOSYLASE; DOUBLE-STRAND DNAS; GENOMIC REGIONS; HISTONE OCTAMERS; LOCAL SEQUENCES; OXIDATIVE DAMAGE; STRUCTURAL AND DYNAMIC PROPERTIES;

DNA;

DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA GLYCOSYLTRANSFERASE; DOUBLE STRANDED RNA; HISTONE;

ARTICLE; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME ISOLATION; EXCISION REPAIR; HUMAN; IONIZING RADIATION; NUCLEOSOME; PRIORITY JOURNAL;

BASE EXCISION REPAIR (BER); CHROMATIN; DNA DOUBLE-STRAND BREAK FORMATION; DNA ENZYME; DNA GLYCOSYLASES; DNA REPAIR; HISTONE; IONIZING RADIATION; NUCLEOSOMES; OXYGEN RADICALS;

CHROMATIN; DEOXYRIBONUCLEASE (PYRIMIDINE DIMER); DNA; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; HUMANS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEOSOMES; OXIDATION-REDUCTION;

EID: 84904480116     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.571588     Document Type: Article

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