The complexity of DNA double strand breaks is a critical factor enhancing end-resection

DNA Repair

Volumn 12, Issue 11, 2013, Pages 936-946

  Yajima, Hirohiko ^a,b   Fujisawa, Hiroshi ^c   Nakajima, Nakako Izumi ^a,b   Hirakawa, Hirokazu ^a,b   Jeggo, Penelope A ^b,d   Okayasu, Ryuichi ^b   Fujimori, Akira ^a,b  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

ATM; Complex DNA damage structure; CtIP; DNA double strand breaks; DNA end resection; Homologous recombination

Indexed keywords

DNA; DOUBLE STRANDED DNA; HEAVY ION; SINGLE STRANDED DNA;

ANIMAL CELL; ARTICLE; CANCER RADIOTHERAPY; CANCER THERAPY; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA DAMAGE; DNA END JOINING REPAIR; DNA STRAND BREAKAGE; HEAVY ION RADIATION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; LINEAR ENERGY TRANSFER; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; X IRRADIATION;

4′,6-DIAMIDINO-2-PHENYLINDOLE.; ATM; CAMPTOTHECIN; CENP-F; CENTROMERE PROTEIN F; COMPLEX DNA DAMAGE STRUCTURE; CPT; CTIP; DAPI; DNA DOUBLE STRAND BREAKS; DNA END RESECTION; DSBS; HOMOLOGOUS RECOMBINATION; HR; IONIZING RADIATION; IR; LET; LINEAR ENERGY TRANSFER; MEF; MICRO HOMOLOGY-MEDIATED END JOINING; MMEJ; MOUSE EMBRYONIC FIBROBLAST; PHOSPHATIDYL INOSITOL 3′ KINASE-RELATED KINASE; PIKK; RBE; RELATIVE BIOLOGICAL EFFECTIVENESS; REPLICATION PROTEIN A; RPA;

ANIMALS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CARRIER PROTEINS; CELL CYCLE; CELL LINE; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA, SINGLE-STRANDED; HELA CELLS; HETEROCHROMATIN; HUMANS; LINEAR ENERGY TRANSFER; MICE; MORPHOLINES; NUCLEAR PROTEINS; PHOSPHORYLATION; PYRONES; RADIATION, IONIZING; RECOMBINATIONAL DNA REPAIR; REPLICATION PROTEIN A;

EID: 84887133750     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2013.08.009     Document Type: Article

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