Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes

International Journal of Biochemistry and Cell Biology

Volumn 67, Issue , 2015, Pages 101-109

  Zhang, Mingcai ^a   Egan, Brian ^a   Wang, Jinxi ^a,b  

^a Harrington Laboratory for Molecular Orthopedics   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokine; Epigenetics; Gene expression; Osteoarthritis; Proteinase; Transcription factor

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEINASE; SCLEROPROTEIN; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNTRANSLATED RNA; AGGRECAN; AGGRECANASE; COLLAGEN; COLLAGENASE; HISTONE; NFATC2 PROTEIN, HUMAN; RUNX2 PROTEIN, HUMAN; SOX9 PROTEIN, HUMAN; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9;

A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 4 GENE; A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 5 GENE; AGGRECAN GENE; AGGRECANASE GENE; ARTICLE; BIOSYNTHESIS; CARTILAGE CELL; CATABOLISM; CELL ACTIVITY; COLLAGEN TYPE 2 GENE; COLLAGEN TYPE 9 GENE; COLLAGENASE GENE; DISEASE COURSE; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC REGULATION; HISTONE MODIFICATION; HUMAN; MATRIX METALLOPROTEINASE 13 GENE; MATRIX METALLOPROTEINASE 3 GENE; MATRIX METALLOPROTEINASE 9 GENE; NONHUMAN; NUCLEAR FACTOR OF ACTIVATED T CELLS 1 GENE; OSTEOARTHRITIS; PATHOGENESIS; RUNT RELATED TRANSCRIPTION FACTOR 2 GENE; SOX9 GENE; ARTICULAR CARTILAGE; CHONDROCYTE; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY;

AGGRECANS; CARTILAGE, ARTICULAR; CHONDROCYTES; COLLAGEN; COLLAGENASES; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CYTOKINES; DNA METHYLATION; ENDOPEPTIDASES; EPIGENESIS, GENETIC; HISTONES; HUMANS; NFATC TRANSCRIPTION FACTORS; OSTEOARTHRITIS; RNA, UNTRANSLATED; SOX9 TRANSCRIPTION FACTOR;

EID: 84940893123     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2015.04.019     Document Type: Review

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