Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis

Osteoarthritis and Cartilage

Volumn 18, Issue 1, 2010, Pages 24-33

  Blagojevic, M ^a   Jinks, C ^a   Jeffery, A ^b   Jordan, K P ^a  

^a KEELE UNIVERSITY   (United Kingdom)

^b IQVIA   (United States)

Author keywords

Incidence; Knee; Knee pain; Meta analysis; Osteoarthritis; Risk factors; Systematic review

Indexed keywords

AGE; ARTICLE; BODY MASS; BONE DENSITY; COMORBIDITY; DEMOGRAPHY; DEPRESSION; EXERCISE; HUMAN; HYPERTENSION; HYSTERECTOMY; INCIDENCE; KNEE INJURY; KNEE OSTEOARTHRITIS; KNEE PAIN; MENISCECTOMY; OBESITY; OCCUPATIONAL HAZARD; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RISK FACTOR; SEX DIFFERENCE; SMOKING; SYSTEMATIC REVIEW;

AGE FACTORS; AGED; BODY MASS INDEX; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; HUMANS; INCIDENCE; KNEE INJURIES; MALE; MIDDLE AGED; OBESITY; OSTEOARTHRITIS, KNEE; PAIN; RISK FACTORS; SEX FACTORS; SMOKING;

EID: 72149116709     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2009.08.010     Document Type: Article

References (101)

1. Urwin M., Symmons D., Allison T., Brammah T., Busby H., Roxby M., et al. Estimating the burden of musculoskeletal disorders in the community: the comparative prevalence of symptoms at different anatomical sites, and the relation to social deprivation. Ann Rheum Dis 57 (1998) 649-655
2. Thomas E., Peat G., Harris L., Wilkie R., and Croft P.R. The prevalence of pain and pain interference in a general population of older adults: cross-sectional findings from the North Staffordshire Osteoarthritis Project (NorStOP). Pain 110 (2004) 361-368
3. Jinks C., Jordan K., Ong B.N., and Croft P. A brief screening tool for knee pain in primary care (KNEST). 2. Results from a survey in the general population aged 50 and over. Rheumatology (Oxford) 43 (2004) 55-61
4. Jinks C., Jordan K., and Croft P. Osteoarthritis as a public health problem: the impact of developing knee pain on physical function in adults living in the community: (KNEST 3). Rheumatology 46 (2007) 877-881
5. Donald I.P., and Foy C. A longitudinal study of joint pain in older people. Rheumatology (Oxford) 43 (2004) 1256-1260
6. Bierma-Zeinstra S.M., and Koes B.W. Risk factors and prognostic factors of hip and knee osteoarthritis. Nat Clin Pract Rheumatol 3 (2007) 78-85
7. Mallen C.D., Peat G., Thomas E., Dunn K.M., and Croft P.R. Prognostic factors for musculoskeletal pain in primary care: a systematic review. Br J Gen Pract 57 (2007) 655-661
8. Van Dijk G.M., Dekker J., Veenhof C., and van den Ende C.H. Course of functional status and pain in osteoarthritis of the hip or knee: a systematic review of the literature. Arthritis Rheum 55 (2006) 779-785
9. Jordan K., Jinks C., and Croft P. A prospective study of the consulting behaviour of older people with knee pain. Br J Gen Pract 56 (2006) 269-276
10. Jinks C., Jordan K.P., Blagojevic M., and Croft P. Predictors of onset and progression of knee pain in adults living in the community. A prospective study. Rheumatology (Oxford) 47 (2008) 368-374
11. Shrout P.E., and Fleiss J.L. Intraclass correlations - uses in assessing rater reliability. Psychol Bull 86 (1979) 420-428
12. Higgins J.P., Thompson S.G., Deeks J.J., and Altman D.G. Measuring inconsistency in meta-analyses. BMJ 327 (2003) 557-560
13. DerSimonian R., and Laird N. Meta-analysis in clinical trials. Control Clin Trials 7 (1986) 177-188
14. Egger M., Davey Smith G., Schneider M., and Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 315 (1997) 629-634
15. Holmberg S., Thelin A., and Thelin N. Knee osteoarthritis and body mass index: a population-based case-control study. Scand J Rheumatol 34 (2005) 59-64
16. Harms S., Larson R., Sahmoun A.E., and Beal J.R. Obesity increases the likelihood of total joint replacement surgery among younger adults. Int Orthop 31 (2007) 23-26
17. Hochberg M., Lethbridge C., and Tobin J. Bone mineral density and osteoarthritis: data from the Baltimore Longitudinal Study of Aging. Osteoarthritis Cartilage 12 (2004) S45-S48
18. Dawson J., Juszczak E., Thorogood M., Marks S.A., Dodd C., and Fitzpatrick R. An investigation of risk factors for symptomatic osteoarthritis of the knee in women using a life course approach. J Epidemiol Community Health 57 (2003) 823-830
19. Hootman J., Macera C., Helmick C., and Blair S. Influence of physical activity-related joint stress on the risk of self-reported hip/knee osteoarthritis: a new method to quantify physical activity. Prev Med 36 (2003) 636-644
20. Manninen P., Heliövaara M., Riihimäki H., and Suoma I. Physical workload and the risk of severe knee osteoarthritis. Scand J Work Environ Health 28 (2002) 25-32
21. Sutton A.J., Muir K.R., Mockett S., and Fentem P. A case-control study to investigate the relation between low and moderate levels of physical activity and osteoarthritis of the knee using data collected as part of the Allied Dunbar National Fitness Survey. Ann Rheum Dis 60 (2001) 756-764
22. Felson D.T., Zhang Y., Hannan M.T., Naimark A., Weissman B., Aliabadi P., et al. Risk factors for incident radiographic knee osteoarthritis in the elderly: the Framingham Study. Arthritis Rheum 40 (1997) 728-733
23. McAlindon T., Zhang Y., Hannan M., Naimark A., Weissman B., Castelli W., et al. Are risk factors for patellofemoral and tibiofemoral knee osteoarthritis different?. J Rheumatol 23 (1996) 332-337
24. Manninen P., Riihimäki H., Heliövaara M., and Mäkelä P. Overweight, gender and knee osteoarthritis. Int J Obes Relat Metab Disord 20 (1996) 595-597
25. Coggon D., Croft P., Kellingray S., Barrett D., McLaren M., and Cooper C. Occupational physical activities and osteoarthritis of the knee. Arthritis Rheum 43 (2000) 1443-1449
26. Cooper C., Snow S., McAlindon T.E., Kellingray S., Stuart B., Coggon D., et al. Risk factors for the incidence and progression of radiographic knee osteoarthritis. Arthritis Rheum 43 (2000) 995-1000
27. Cheng Y., Macera C.A., Davis D.R., Ainsworth B.E., Troped P.J., and Blair S.N. Physical activity and self-reported, physician-diagnosed osteoarthritis: is physical activity a risk factor?. J Clin Epidemiol 53 (2000) 315-322
28. Gelber A.C., Hochberg M.C., Mead L.A., Wang N.Y., Wigley F.M., and Klag M.J. Body mass index in young men and the risk of subsequent knee and hip osteoarthritis. Am J Med 107 (1999) 542-548
29. Oliveria S.A., Felson D.T., Cirillo P.A., Reed J.I., and Walker A.M. Body weight, body mass index, and incident symptomatic osteoarthritis of the hand, hip, and knee. Epidemiology (Cambridge, Mass) 10 (1999) 161-166
30. Hart D.J., Doyle D.V., and Spector T.D. Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford Study. Arthritis Rheum 42 (1999) 17-24
31. Kujala U.M., Kettunen J., Paananen H., Aalto T., Battié M.C., Impivaara O., et al. Knee osteoarthritis in former runners, soccer players, weight lifters, and shooters. Arthritis Rheum 38 (1995) 539-546
32. Spector T.D., Hart D.J., and Doyle D.V. Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population: the effect of obesity. Ann Rheum Dis 53 (1994) 565-568
33. Cooper C., McAlindon T., Snow S., Vines K., Young P., Kirwan J., et al. Mechanical and constitutional risk factors for symptomatic knee osteoarthritis: differences between medial tibiofemoral and patellofemoral disease. J Rheumatol 21 (1994) 307-313
34. Felson D.T., Zhang Y., Anthony J.M., Naimark A., and Anderson J.J. Weight loss reduces the risk for symptomatic knee osteoarthritis in women. The Framingham Study. Ann Intern Med 116 (1992) 535-539
35. Felson D.T., Anderson J.J., Naimark A., Walker A.M., and Meenan R.F. Obesity and knee osteoarthritis. The Framingham Study. Ann Intern Med 109 (1988) 18-24
36. Manninen P., Riihimaki H., Heliövaara M., and Suomalainen O. Weight changes and the risk of knee osteoarthritis requiring arthroplasty. Ann Rheum Dis 63 11 (2004) 1434-1437
37. Lachance L., Sowers M.F., Jamadar D., and Hochberg M. The natural history of emergent osteoarthritis of the knee in women. Osteoarthritis Cartilage 10 (2002) 849-854
38. Shiozaki H., Koga Y., Omori G., and Tamaki M. Obesity and osteoarthritis of the knee in women: results from the Matsudai Knee Osteoarthritis Survey. Knee 6 (1999) 189-192
39. Ettinger W.H., Davis M.A., Neuhaus J.M., and Mallon K.P. Long-term physical functioning in persons with knee osteoarthritis from NHANES I: effects of comorbid medical conditions. J Clin Epidemiol 47 (1994) 809-815
40. Järvholm B., Lewold S., Malchau H., and Vingard E. Age, bodyweight, smoking habits and the risk of severe osteoarthritis in the hip and knee in men. Eur J Epidemiol 20 (2005) 537-542
41. Kohatsu N.D., and Schurman D.J. Risk factors for the development of osteoarthrosis of the knee. Clin Orthop Relat Res 261 (1990) 242-246
42. Sahlstrom A., and Montgomery F. Risk analysis of occupational factors influencing the development of arthrosis of the knee. Eur J Epidemiol 13 (1997) 675-679
43. Seavey W.G., Kurata J.H., and Cohen R.D. Risk factors for incident self-reported arthritis in a 20 year followup of the Alameda County Study Cohort. J Rheumatol 30 (2003) 2103-2111
44. Sandmark H., Hogstedt C., Lewold S., and Vingσrd E. Osteoarthrosis of the knee in men and women in association with overweight, smoking, and hormone therapy. Ann Rheum Dis 58 (1999) 151-155
45. D'Souza J.C., Werner A.W., Keyserling W.M., Gillespie B., Rabourn R., Ulin S., et al. Occupational activities and knee osteoarthritis: an analysis of the third National Health and Nutrition Examination Survey (NHANES III) using expert ratings of job categories. Am J Ind Med 51 (2008) 37-46
46. Liu B., Balkwill A., Banks E., Cooper C., Green J., and Beral V. Relationship of height, weight and body mass index to the risk of hip and knee replacements in middle-aged women. Rheumatology 46 (2007) 861-867
47. Reijman M., Pols H.A.P., Bergink A.P., Hazes J.M.W., Belo J.N., Lievense A., et al. Body mass index associated with onset and progression of osteoarthritis of the knee but not of the hip: the Rotterdam Study. Ann Rheum Dis 66 (2007) 158-162
48. Thelin N., Holmberg S., and Thelin A. Knee injuries account for the sports-related increased risk of knee osteoarthritis. Scand J Med Sci Sports 16 (2006) 329-333
49. Jinks C., Jordan K., and Croft P. Disabling knee pain - another consequence of obesity: results from a prospective cohort study. BMC Public Health 6 (2006) 258
50. Szoeke C.E., Cicuttini F.M., Guthrie J.R., Clark M.S., and Dennerstein L. Factors affecting the prevalence of osteoarthritis in healthy middle-aged women: data from the longitudinal Melbourne Women's Midlife Health Project. Bone 39 (2006) 1149-1155
51. Yoshimura N., Nishioka S., Kinoshita H., Hori N., Nishioka T., Ryujin M., et al. Risk factors for knee osteoarthritis in Japanese women: heavy weight, previous joint injuries, and occupational activities. J Rheumatol 31 (2004) 157-162
52. Yoshimura N., Kinoshita H., Hori N., Nishioka T., Ryujin M., Mantani Y., et al. Risk factors for knee osteoarthritis in Japanese men: a case-control study. Mod Rheumatol 16 (2006) 24-29
53. Wilder F.V., Hall B.J., Barrett Jr. J.P., and Lemrow N.B. History of acute knee injury and osteoarthritis of the knee: a prospective epidemiological assessment. The Clearwater Osteoarthritis Study. Osteoarthritis Cartilage 10 (2002) 611-616
54. Lau E.C., Cooper C., Lam D., Chan V.N., Tsang K.K., and Sham A. Factors associated with osteoarthritis of the hip and knee in Hong Kong Chinese: obesity, joint injury, and occupational activities. Am J Epidemiol 152 (2000) 855-862
55. Gelber A.C., Hochberg M.C., Mead L.A., Wang N.Y., Wigley F.M., and Klag M.J. Joint injury in young adults and risk for subsequent knee and hip osteoarthritis. Ann Intern Med 133 (2000) 321-328
56. Wilder F.V., Hall B.J., and Barrett J.P. Smoking and osteoarthritis: is there an association? The Clearwater Osteoarthritis Study. Osteoarthritis Cartilage 11 (2003) 29-35
57. Manninen P., Riihimaki H., Heliovaara M., and Suomalainen O. Physical exercise and risk of severe knee osteoarthritis requiring arthroplasty. Rheumatology (Oxford) 40 (2001) 432-437
58. Felson D.T., Anderson J.J., Naimark A., Hannan M.T., Kannel W.B., and Meenan R. Does smoking protect against osteoarthritis?. Arthritis Rheum 32 (1989) 166-172
59. Samanta A., Jones A., Regan M., Wilson S., and Doherty M. Is osteoarthritis in women affected by hormonal changes or smoking?. Br J Rheumatol 32 (1993) 366-370
60. Felson D.T., Zhang Y., Hannan M.T., Naimark A., Weissman B.N., Aliabadi P., et al. The incidence and natural history of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study. Arthritis Rheum 38 (1995) 1500-1505
61. Borrero S., Kwoh C.K., Sartorius J., and Ibrahim S.A. Brief report: gender and total knee/hip arthroplasty utilization rate in the VA system. J Gen Intern Med 21 Suppl 3 (2006) S54-S57
62. Soeroso J., Dans L.F., Amarillo M.L., Santoso G.H., and Kalim H. Risk factors of symptomatic osteoarthritis of the knee at a hospital in Indonesia. APLAR J Rheumatol 8 (2005) 106-113
63. Oliveria S.A., Felson D.T., Reed J.I., Cirillo P.A., and Walker A.M. Incidence of symptomatic hand, hip, and knee osteoarthritis among patients in a health maintenance organization. Arthritis Rheum 38 (1995) 1134-1141
64. Dahaghin S., Bierma Z., Reijman M., Pols H.A.P., Hazes J.M.W., and Koes B.W. Does hand osteoarthritis predict future hip or knee osteoarthritis?. Arthritis Rheum 52 (2005) 3520-3527
65. Deacon A., Bennell K., Kiss Z.S., Crossley K., and Brukner P. Osteoarthritis of the knee in retired, elite Australian Rules footballers. Med J Aust 166 (1997) 187-190
66. Sandmark H., Hogstedt C., and Vingσrd E. Primary osteoarthrosis of the knee in men and women as a result of lifelong physical load from work. Scand J Work Environ Health 26 (2000) 20-25
67. Cooper C., McAlindon T., Coggon D., Egger P., and Dieppe P. Occupational activity and osteoarthritis of the knee. Ann Rheum Dis 53 (1994) 90-93
68. Tangtrakulwanich B., Chongsuvivatwong V., and Geater A.F. Associations between floor activities and knee osteoarthritis in Thai Buddhist monks: the Songkhla study. J Med Assoc Thailand 89 (2006) 1902-1908
69. Felson D.T., Hannan M.T., Naimark A., Berkeley J., Gordon G., Wilson P.W., et al. Occupational physical demands, knee bending, and knee osteoarthritis: results from the Framingham Study. J Rheumatol 18 (1991) 1587-1592
70. Holmberg S., Thelin A., and Thelin N. Is there an increased risk of knee osteoarthritis among farmers? A population-based case-control study. Int Arch Occup Environ Health 77 (2004) 345-350
71. Holmberg S., Stiernström E., Thelin A., and Svärdsudd K. Musculoskeletal symptoms among farmers and non-farmers: a population-based study. Int J Occup Environ Health 8 (2002) 339-345
72. Vingσrd E., Alfredsson L., Goldie I., and Hogstedt C. Occupation and osteoarthrosis of the hip and knee: a register-based cohort study. Int J Epidemiol 20 (1991) 1025-1031
73. Sandmark H. Musculoskeletal dysfunction in physical education teachers. Occup Environ Med 57 (2000) 673-677
74. Felson D.T., Nui J., Clancy M., Sack B., Aliabadi P., and Zhang Y. Effect of recreational physical activities on the development of knee osteoarthritis in older adults of different weights: the Framingham Study. Arthritis Rheum 57 (2007) 6-12
75. Konradsen L., Hansen E.M., and Sondergaard L. Long distance running and osteoarthrosis. Am J Sports Med 18 (1990) 379-381
76. Panush R.S., Schmidt C., Caldwell J.R., Edwards N.L., Longley S., Yonker R., et al. Is running associated with degenerative joint disease?. J Am Med Assoc 255 (1986) 1152-1154
77. Sohn R.S., and Micheli L.J. The effect of running on the pathogenesis of osteoarthritis of the hips and knees. Clin Orthop Relat Res 198 (1985) 106-109
78. Kujala U.M., Sarna S., Kaprio J., Koskenvuo M., and Karjalainen J. Heart attacks and lower-limb function in master endurance athletes. Med Sci Sports Exerc 31 (1999) 1041-1046
79. Rogers L.Q., Macera C.A., Hootman J.M., Ainsworth B.E., and Blairi S.N. The association between joint stress from physical activity and self-reported osteoarthritis: an analysis of the Cooper Clinic data. Osteoarthritis Cartilage 10 (2002) 617-622
80. McAlindon T.E., Wilson P.W., Aliabadi P., Weissman B., and Felson D.T. Level of physical activity and the risk of radiographic and symptomatic knee osteoarthritis in the elderly: the Framingham Study. Am J Med 106 (1999) 151-157
81. Imeokparia R.L., Barrett J.P., Arrieta M.I., Leaverton P.E., Wilson A.A., Hall B.J., et al. Physical activity as a risk factor for osteoarthritis of the knee. Ann Epidemiol 4 (1994) 221-230
82. Hannan M.T., Felson D.T., Anderson J.J., and Naimark A. Habitual physical activity is not associated with knee osteoarthritis: the Framingham Study. J Rheumatol 20 (1993) 704-709
83. Sandmark H., and Vingσrd E. Sports and risk for severe osteoarthrosis of the knee. Scand J Med Sci Sports 9 (1999) 279-284
84. Spector T.D., Harris P.A., Hart D.J., Cicuttini F.M., Nandra D., Etherington J., et al. Risk of osteoarthritis associated with long-term weight-bearing sports: a radiologic survey of the hips and knees in female ex-athletes and population controls. Arthritis Rheum 39 (1996) 988-995
85. Roos H., Lindberg H., GΣrdsell P., Lohmander L.S., and Wingstrand H. The prevalence of gonarthrosis and its relation to meniscectomy in former soccer players. Am J Sports Med 22 (1994) 219-222
86. Kettunen J.A., Kujala U.M., Kaprio J., Koskenvuo M., and Sarna S. Lower-limb function among former elite male athletes. Am J Sports Med 29 (2001) 2-8
87. Klunder K.B., Rud B., and Hansen J. Osteoarthritis of the hip and knee joint in retired football players. Acta Orthop Scand 51 (1980) 925-927
88. Hannan M.T., Felson D.T., Anderson J.J., Naimark A., and Kannel W.B. Estrogen use and radiographic osteoarthritis of the knee in women. The Framingham Osteoarthritis Study. Arthritis Rheum 33 (1990) 525-532
89. Zhang Y.Q., McAlindon T.E., Hannan M.T., Chaisson C.E., Klein R., Wilson P.W.F., et al. Estrogen replacement therapy and worsening of radiographic knee osteoarthritis. Arthritis Rheum 41 (1998) 1867-1873
90. Spector T.D., Hart D.J., Brown P., Almeyda J., Dacre J.E., Doyle D.V., et al. Frequency of osteoarthritis in hysterectomized women. J Rheumatol 18 (1991) 1877-1883
91. Palmer K.T., Reading I., Calnan M., Linaker C., and Coggon D. Does knee pain in the community behave like a regional pain syndrome? Prospective cohort study of incidence and persistence. Ann Rheum Dis 66 (2007) 1190-1194
92. Zhang Y., Hannan M.T., Chaisson C.E., McAlindon T.E., Evans S.R., Aliabadi P., et al. Bone mineral density and risk of incident and progressive radiographic knee osteoarthritis in women: the Framingham Study. J Rheumatol 27 (2000) 1032-1037
93. Bergink A.P., Uitterlinden A.G., van L., Hofman A., Verhaar J., and Pols H.A.P. Bone mineral density and vertebral fracture history are associated with incident and progressive radiographic knee osteoarthritis in elderly men and women: the Rotterdam Study. Bone 37 (2005) 446-456
94. Hart D.J., Cronin C., Daniels M., Worthy T., Doyle D.V., and Spector T.D. The relationship of bone density and fracture to incident and progressive radiographic osteoarthritis of the knee: the Chingford Study. Arthritis Rheum 46 (2002) 92-99
95. Englund M., and Lohmander L.S. Risk factors for symptomatic knee osteoarthritis fifteen to twenty-two years after meniscectomy. Arthritis Rheum 50 (2004) 2811-2819
96. Englund M., Roos E.M., and Lohmander L.S. Impact of type of meniscal tear on radiographic and symptomatic knee osteoarthritis: a sixteen-year followup of meniscectomy with matched controls. Arthritis Rheum 48 (2003) 2178-2187
97. Roos H., Lauren M., Adalberth T., Roos E.M., Jonsson K., and Lohmander L.S. Knee osteoarthritis after meniscectomy: prevalence of radiographic changes after twenty-one years, compared with matched controls. Arthritis Rheum 41 (1998) 687-693
98. Dolan A., Hart D., Doyle D.V., Grahame R., and Spector T. The relationship of joint hypermobility, bone mineral density, and osteoarthritis in the general population: the Chingford Study. J Rheumatol 30 (2003) 799-803
99. Zhang W., Robertson J., Doherty S., Liu J.J., Maciewicz R.A., Muir K.R., et al. Index to ring finger length ratio and the risk of osteoarthritis. Arthritis Rheum 58 (2007) 137-144
100. Molarius A., Seidell J.C., Kuulasmaa K., Dobson A.J., and Sans S. Smoking and relative body weight: an international perspective from the WHO MONICA Project. J Epidemiol Community Health 51 (1997) 252-260
101. Belo J.N., Berger M.Y., Reijman M., Koes B.W., and Bierma-Zeinstra S.M. Prognostic factors of progression of osteoarthritis of the knee: a systematic review of observational studies. Arthritis Rheum 57 (2007) 13-26