Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes

Osteoarthritis and Cartilage

Volumn 21, Issue 12, 2013, Pages 1987-1996

  Wang, J H ^a   Shih, K S ^b,c,d   Wu, Y W ^a   Wang, A W ^e   Yang, C R ^e  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Histone deacetylase; Interleukin 1; Interleukin 1 receptor associated kinase 1; MicroRNA; Tumor necrosis factor receptor associated factor 6

Indexed keywords

HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 6; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1BETA; MICRORNA 146A; PANOBINOSTAT; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; VORINOSTAT;

ANTIRHEUMATIC ACTIVITY; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME REGULATION; GENETIC TRANSFECTION; HUMAN; IMMUNOCHEMISTRY; KNEE ARTHROSCOPY; OSTEOARTHRITIS; OSTEOARTHRITIS FIBROBLAST LIKE SYNOVIOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; REPORTER GENE; SIGNAL TRANSDUCTION; SYNOVIOCYTE; TIME TO TREATMENT;

HISTONE DEACETYLASE; INTERLEUKIN-1; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-1; MICRORNA; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTOR 6;

CASE-CONTROL STUDIES; CELLS, CULTURED; FIBROBLASTS; GENE EXPRESSION; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; INDOLES; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-1BETA; MICRORNAS; NF-KAPPA B; OSTEOARTHRITIS; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; TNF RECEPTOR-ASSOCIATED FACTOR 6;

EID: 84888879919     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2013.09.008     Document Type: Article

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