Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145)

Journal of Biological Chemistry

Volumn 287, Issue 2, 2012, Pages 916-924

  Martinez Sanchez, Aida ^a   Dudek, Katarzyna A ^a   Murphy, Chris L ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICULAR CARTILAGES; CARTILAGE EXTRACELLULAR MATRIXES; CARTILAGE REPAIR; CHONDROCYTES; EXTRACELLULAR MATRICES; HEALTHY HUMANS; HUMAN CELLS; MASTER REGULATORS; MATRIX SYNTHESIS; MICRORNAS; WEIGHT BEARING;

BODY FLUIDS; CARTILAGE; GENES; TISSUE; TRANSCRIPTION; TRANSCRIPTION FACTORS;

JOINTS (ANATOMY);

COLLAGENASE 3; MICRORNA; MICRORNA 140; MICRORNA 145; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; BINDING AFFINITY; BINDING SITE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL FUNCTION; COL2A1 GENE; CONTROLLED STUDY; GENE; GENE FUNCTION; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION;

3' UNTRANSLATED REGIONS; AGGRECANS; ANIMALS; CAMPOMELIC DYSPLASIA; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; GENE EXPRESSION REGULATION; HUMANS; MICE; MICRORNAS; MUTATION; SOX9 TRANSCRIPTION FACTOR;

MUS;

EID: 84855502155     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.302430     Document Type: Article

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