-
1
-
-
0025776382
-
Catabolism of aggrecan in cartilage explants: Identification of a major cleavage site within the interglobular domain
-
Sandy JD, Neame PJ, Boynton RE, Flannery CR. Catabolism of aggrecan in cartilage explants: identification of a major cleavage site within the interglobular domain. J Biol Chem 1991;266:8683-5.
-
(1991)
J Biol Chem
, vol.266
, pp. 8683-8685
-
-
Sandy, J.D.1
Neame, P.J.2
Boynton, R.E.3
Flannery, C.R.4
-
2
-
-
0026771893
-
N-terminal sequencing of proteoglycan fragments from medium of interleukin-1-treated articular-cartilage cultures: Putative site(s) of enzyme cleavage
-
Loulakis P, Shrikhande A, Davis G, Maniglia CA. N-terminal sequencing of proteoglycan fragments from medium of interleukin-1-treated articular-cartilage cultures: putative site(s) of enzyme cleavage. Biochem J 1992;284:589-93.
-
(1992)
Biochem J
, vol.284
, pp. 589-593
-
-
Loulakis, P.1
Shrikhande, A.2
Davis, G.3
Maniglia, C.A.4
-
4
-
-
0026682509
-
The structure of aggrecan fragments in human synovial fluid: Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain
-
Sandy JD, Flannery CR, Neame PJ, Lohmander LS. The structure of aggrecan fragments in human synovial fluid: evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain. J Clin Invest 1992;89:1512-6.
-
(1992)
J Clin Invest
, vol.89
, pp. 1512-1516
-
-
Sandy, J.D.1
Flannery, C.R.2
Neame, P.J.3
Lohmander, L.S.4
-
5
-
-
0027445981
-
The structure of aggrecan fragments in human synovial fluid: Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis
-
Lohmander LS, Neame PJ, Sandy JD. The structure of aggrecan fragments in human synovial fluid: evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis. Arthritis Rheum 1993;36:1214-22.
-
(1993)
Arthritis Rheum
, vol.36
, pp. 1214-1222
-
-
Lohmander, L.S.1
Neame, P.J.2
Sandy, J.D.3
-
6
-
-
0029085839
-
Development of a cleavage-site-specific monoclonal antibody for detecting metalloproteinase- derived aggrecan fragments: Detection of fragments in human synovial fluids
-
Fosang AJ, Last K, Gardiner P, Jackson DC, Brown L. Development of a cleavage-site-specific monoclonal antibody for detecting metalloproteinase- derived aggrecan fragments: detection of fragments in human synovial fluids. Biochem J 1995;310:337-43.
-
(1995)
Biochem J
, vol.310
, pp. 337-343
-
-
Fosang, A.J.1
Last, K.2
Gardiner, P.3
Jackson, D.C.4
Brown, L.5
-
7
-
-
0029852094
-
Aggrecan is degraded by matrix metalloproteinases in human arthritis: Evidence that matrix metalloproteinase and aggrecanase activities can be independent
-
Fosang AJ, Last K, Maciewicz RA. Aggrecan is degraded by matrix metalloproteinases in human arthritis: evidence that matrix metalloproteinase and aggrecanase activities can be independent. J Clin Invest 1996;98:2292-9.
-
(1996)
J Clin Invest
, vol.98
, pp. 2292-2299
-
-
Fosang, A.J.1
Last, K.2
Maciewicz, R.A.3
-
8
-
-
30544448357
-
Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments
-
Struglics A, Larsson S, Pratta MA, Kumar S, Lark MW, Lohmander LS. Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments. Osteoarthritis Cartilage 2006;14:101-13.
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 101-113
-
-
Struglics, A.1
Larsson, S.2
Pratta, M.A.3
Kumar, S.4
Lark, M.W.5
Lohmander, L.S.6
-
9
-
-
0345211445
-
Purification and cloning of aggrecanase-1: A member of the ADAMTS family of proteins
-
Tortorella MD, Burn TC, Pratta MA, Abbaszade I, Hollis JM, Liu R, et al. Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins. Science 1999;284:664-6.
-
(1999)
Science
, vol.284
, pp. 664-666
-
-
Tortorella, M.D.1
Burn, T.C.2
Pratta, M.A.3
Abbaszade, I.4
Hollis, J.M.5
Liu, R.6
-
10
-
-
0033551844
-
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
-
Abbaszade I, Liu RQ, Yang F, Rosenfeld SA, Ross OH, Link JR, et al. Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family. J Biol Chem 1999;274:23443-50.
-
(1999)
J Biol Chem
, vol.274
, pp. 23443-23450
-
-
Abbaszade, I.1
Liu, R.Q.2
Yang, F.3
Rosenfeld, S.A.4
Ross, O.H.5
Link, J.R.6
-
11
-
-
0034604613
-
ADAMTS-1 cleaves a cartilage proteoglycan, aggrecan
-
Kuno K, Okada Y, Kawashima H, Nakamura H, Miyasaka M, Ohno H, et al. ADAMTS-1 cleaves a cartilage proteoglycan, aggrecan. FEBS Lett 2000;478:241-5.
-
(2000)
FEBS Lett
, vol.478
, pp. 241-245
-
-
Kuno, K.1
Okada, Y.2
Kawashima, H.3
Nakamura, H.4
Miyasaka, M.5
Ohno, H.6
-
12
-
-
3543043776
-
ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage
-
Collins-Racie LA, Flannery CR, Zeng W, Corcoran C, Annis-Freeman B, Agostino MJ, et al. ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage. Matrix Biol 2004;23:219-30.
-
(2004)
Matrix Biol
, vol.23
, pp. 219-230
-
-
Collins-Racie, L.A.1
Flannery, C.R.2
Zeng, W.3
Corcoran, C.4
Annis-Freeman, B.5
Agostino, M.J.6
-
13
-
-
0038237345
-
Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1
-
Somerville RP, Longpre JM, Jungers KA, Engle JM, Ross M, Evanko S, et al. Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1. J Biol Chem 2003;278:9503-13.
-
(2003)
J Biol Chem
, vol.278
, pp. 9503-9513
-
-
Somerville, R.P.1
Longpre, J.M.2
Jungers, K.A.3
Engle, J.M.4
Ross, M.5
Evanko, S.6
-
14
-
-
33644883338
-
Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: Comparative analyses with ADAMTS-5, -9, -16 and -18
-
Zeng W, Corcoran C, Collins-Racie LA, LaVallie ER, Morris EA, Flannery CR. Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18. Biochim Biophys Acta 2006;1760:517-24.
-
(2006)
Biochim Biophys Acta
, vol.1760
, pp. 517-524
-
-
Zeng, W.1
Corcoran, C.2
Collins-Racie, L.A.3
LaVallie, E.R.4
Morris, E.A.5
Flannery, C.R.6
-
15
-
-
0032533543
-
An aggrecan-degrading activity associated with chondrocyte membranes
-
Billington CJ, Clark IM, Cawston TE. An aggrecan-degrading activity associated with chondrocyte membranes. Biochem J 1998;336:207-12.
-
(1998)
Biochem J
, vol.336
, pp. 207-212
-
-
Billington, C.J.1
Clark, I.M.2
Cawston, T.E.3
-
16
-
-
0032515157
-
Differential expression of aggrecanase and matrix metalloproteinase activity in chondrocytes isolated from bovine and porcine articular cartilage
-
Hughes CE, Little CB, Buttner FH, Bartnik E, Caterson B. Differential expression of aggrecanase and matrix metalloproteinase activity in chondrocytes isolated from bovine and porcine articular cartilage. J Biol Chem 1998;273:30576-82.
-
(1998)
J Biol Chem
, vol.273
, pp. 30576-30582
-
-
Hughes, C.E.1
Little, C.B.2
Buttner, F.H.3
Bartnik, E.4
Caterson, B.5
-
17
-
-
0032076280
-
Cytokine-induced cartilage proteoglycan degradation is mediated by aggrecanase
-
Arner EC, Hughes CE, Decicco CP, Caterson B, Tortorella MD. Cytokine-induced cartilage proteoglycan degradation is mediated by aggrecanase. Osteoarthritis Cartilage 1998;6:214-28.
-
(1998)
Osteoarthritis Cartilage
, vol.6
, pp. 214-228
-
-
Arner, E.C.1
Hughes, C.E.2
Decicco, C.P.3
Caterson, B.4
Tortorella, M.D.5
-
18
-
-
0036822797
-
Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro
-
Bau B, Gebhard PM, Haag J, Knorr T, Bartnik E, Aigner T. Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro. Arthritis Rheum 2002;46:2648-57.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2648-2657
-
-
Bau, B.1
Gebhard, P.M.2
Haag, J.3
Knorr, T.4
Bartnik, E.5
Aigner, T.6
-
19
-
-
33847010576
-
Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5
-
Song RH, Tortorella MD, Malfait AM, Alston JT, Yang Z, Arner EC, et al. Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5. Arthritis Rheum 2007;56:575-85.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 575-585
-
-
Song, R.H.1
Tortorella, M.D.2
Malfait, A.M.3
Alston, J.T.4
Yang, Z.5
Arner, E.C.6
-
20
-
-
0034840936
-
The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation
-
Tortorella MD, Malfait AM, Deccico C, Arner E. The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation. Osteoarthritis Cartilage 2001;9:539-52.
-
(2001)
Osteoarthritis Cartilage
, vol.9
, pp. 539-552
-
-
Tortorella, M.D.1
Malfait, A.M.2
Deccico, C.3
Arner, E.4
-
21
-
-
33747640560
-
Protein kinase Cζ is up-regulated in osteoarthritic cartilage and is required for activation of NF-κB by tumor necrosis factor and interleukin-1 in articular chondrocytes
-
LaVallie ER, Chockalingam PS, Collins-Racie LA, Freeman BA, Keohan CC, Leitges M, et al. Protein kinase Cζ is up-regulated in osteoarthritic cartilage and is required for activation of NF-κB by tumor necrosis factor and interleukin-1 in articular chondrocytes. J Biol Chem 2006;281:24124-37.
-
(2006)
J Biol Chem
, vol.281
, pp. 24124-24137
-
-
LaVallie, E.R.1
Chockalingam, P.S.2
Collins-Racie, L.A.3
Freeman, B.A.4
Keohan, C.C.5
Leitges, M.6
-
22
-
-
0036164196
-
Cyclosporin A inhibition of aggrecanase-mediated proteoglycan catabolism in articular cartilage
-
Little CB, Hughes CE, Curtis CL, Jones SA, Caterson B, Flannery CR. Cyclosporin A inhibition of aggrecanase-mediated proteoglycan catabolism in articular cartilage. Arthritis Rheum 2002;46:124-9.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 124-129
-
-
Little, C.B.1
Hughes, C.E.2
Curtis, C.L.3
Jones, S.A.4
Caterson, B.5
Flannery, C.R.6
-
23
-
-
15844384854
-
ADAMTS-5 is the major aggrecanase in mouse cartilage, in vivo and in vitro
-
Stanton H, Rogerson FM, East CJ, Golub SB, Little CB, Lawlor KE, et al. ADAMTS-5 is the major aggrecanase in mouse cartilage, in vivo and in vitro. Nature 2005;434:648-51.
-
(2005)
Nature
, vol.434
, pp. 648-651
-
-
Stanton, H.1
Rogerson, F.M.2
East, C.J.3
Golub, S.B.4
Little, C.B.5
Lawlor, K.E.6
-
24
-
-
34247891816
-
ADAMTS-5 deficiency blocks aggrecanase cleavage in the interglobular domain but not in the chondroitin sulfate-rich region of aggrecan
-
East CJ, Stanton H, Golub SB, Rogerson FM, Fosang AJ. ADAMTS-5 deficiency blocks aggrecanase cleavage in the interglobular domain but not in the chondroitin sulfate-rich region of aggrecan. J Biol Chem 2007;282:8632-40.
-
(2007)
J Biol Chem
, vol.282
, pp. 8632-8640
-
-
East, C.J.1
Stanton, H.2
Golub, S.B.3
Rogerson, F.M.4
Fosang, A.J.5
-
25
-
-
34848871992
-
Low molecular weight isoforms of the aggrecanases are responsible for the cytokine-induced proteolysis of aggrecan in a porcine chondrocyte culture system
-
Powell AJ, Little CB, Hughes CE. Low molecular weight isoforms of the aggrecanases are responsible for the cytokine-induced proteolysis of aggrecan in a porcine chondrocyte culture system. Arthritis Rheum 2007;56:3010-9.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3010-3019
-
-
Powell, A.J.1
Little, C.B.2
Hughes, C.E.3
-
26
-
-
0037151084
-
Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage
-
Malfait AM, Liu RQ, Ijiri K, Komiya S, Tortorella MD. Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage. J Biol Chem 2002;277:22201-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 22201-22208
-
-
Malfait, A.M.1
Liu, R.Q.2
Ijiri, K.3
Komiya, S.4
Tortorella, M.D.5
-
27
-
-
18744385527
-
Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions
-
Tchetina EV, Squires G, Poole AR. Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions. J Rheumatol 2005;32:876-86.
-
(2005)
J Rheumatol
, vol.32
, pp. 876-886
-
-
Tchetina, E.V.1
Squires, G.2
Poole, A.R.3
-
28
-
-
9144230209
-
Expression profiling of metalloproteinases and their inhibitors in cartilage
-
Kevorkian L, Young DA, Darrah C, Donell ST, Shepstone L, Porter S, et al. Expression profiling of metalloproteinases and their inhibitors in cartilage. Arthritis Rheum 2004;50:131-41.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 131-141
-
-
Kevorkian, L.1
Young, D.A.2
Darrah, C.3
Donell, S.T.4
Shepstone, L.5
Porter, S.6
-
29
-
-
15844413814
-
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
-
Glasson SS, Askew R, Sheppard B, Carito B, Blanchet T, Ma HL, et al. Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature 2005;434:644-8.
-
(2005)
Nature
, vol.434
, pp. 644-648
-
-
Glasson, S.S.1
Askew, R.2
Sheppard, B.3
Carito, B.4
Blanchet, T.5
Ma, H.L.6
-
30
-
-
4043154293
-
Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice
-
Glasson SS, Askew R, Sheppard B, Carito BA, Blanchet T, Ma HL, et al. Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice. Arthritis Rheum 2004;50:2547-58.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2547-2558
-
-
Glasson, S.S.1
Askew, R.2
Sheppard, B.3
Carito, B.A.4
Blanchet, T.5
Ma, H.L.6
-
31
-
-
0034610394
-
Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids
-
Schmidt EE, Taylor DS, Prigge JR, Barnett S, Capecchi MR. Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids. Proc Natl Acad Sci U S A 2000;97:13702-7.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13702-13707
-
-
Schmidt, E.E.1
Taylor, D.S.2
Prigge, J.R.3
Barnett, S.4
Capecchi, M.R.5
-
32
-
-
18644369778
-
ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo
-
Little CB, Mittaz L, Belluoccio D, Rogerson FM, Campbell IK, Meeker CT, et al. ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo. Arthritis Rheum 2005;52:1461-72.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1461-1472
-
-
Little, C.B.1
Mittaz, L.2
Belluoccio, D.3
Rogerson, F.M.4
Campbell, I.K.5
Meeker, C.T.6
-
33
-
-
0019914963
-
A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures
-
Farndale RW, Sayers CA, Barrett AJ. A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures. Connect Tissue Res 1982;9:247-8.
-
(1982)
Connect Tissue Res
, vol.9
, pp. 247-248
-
-
Farndale, R.W.1
Sayers, C.A.2
Barrett, A.J.3
-
34
-
-
0034693167
-
Mutations in the interglobular domain of aggrecan alter matrix metalloproteinase and aggrecanase cleavage patterns: Evidence that matrix metalloproteinase cleavage interferes with aggrecanase activity
-
Mercuri FA, Maciewicz RA, Tart J, Last K, Fosang AJ. Mutations in the interglobular domain of aggrecan alter matrix metalloproteinase and aggrecanase cleavage patterns: evidence that matrix metalloproteinase cleavage interferes with aggrecanase activity. J Biol Chem 2000;275:33038-45.
-
(2000)
J Biol Chem
, vol.275
, pp. 33038-33045
-
-
Mercuri, F.A.1
Maciewicz, R.A.2
Tart, J.3
Last, K.4
Fosang, A.J.5
-
35
-
-
0034674771
-
Sites of aggrecan cleavage of recombinant human aggrecanase-1 (ADAMTS-4)
-
Tortorella MD, Pratta MA, Liu RQ, Austin J, Ross OH, Abbaszade I, et al. Sites of aggrecan cleavage of recombinant human aggrecanase-1 (ADAMTS-4). J Biol Chem 2000;275:18566-73.
-
(2000)
J Biol Chem
, vol.275
, pp. 18566-18573
-
-
Tortorella, M.D.1
Pratta, M.A.2
Liu, R.Q.3
Austin, J.4
Ross, O.H.5
Abbaszade, I.6
-
36
-
-
18744437369
-
Aggrecan degradation in human cartilage: Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints
-
Lark MW, Bayne EK, Flanagan J, Harper CF, Hoerrner LA, Hutchinson NI, et al. Aggrecan degradation in human cartilage: evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints. J Clin Invest 1997;100:93-106.
-
(1997)
J Clin Invest
, vol.100
, pp. 93-106
-
-
Lark, M.W.1
Bayne, E.K.2
Flanagan, J.3
Harper, C.F.4
Hoerrner, L.A.5
Hutchinson, N.I.6
-
37
-
-
36048985974
-
Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents progression of osteoarthritis
-
Majumdar MK, Askew R, Schelling S, Stedman N, Blanchet T, Hopkins B, et al. Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents progression of osteoarthritis. Arthritis Rheum 2007;56:3670-4.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3670-3674
-
-
Majumdar, M.K.1
Askew, R.2
Schelling, S.3
Stedman, N.4
Blanchet, T.5
Hopkins, B.6
-
38
-
-
0034306104
-
The intermediates of aggrecanase-dependent cleavage of aggrecan in rat chondrosarcoma cells treated with interleukin-1
-
Sandy JD, Thompson V, Doege K, Verscharen C. The intermediates of aggrecanase-dependent cleavage of aggrecan in rat chondrosarcoma cells treated with interleukin-1. Biochem J 2000;351:161-6.
-
(2000)
Biochem J
, vol.351
, pp. 161-166
-
-
Sandy, J.D.1
Thompson, V.2
Doege, K.3
Verscharen, C.4
-
39
-
-
0035884605
-
Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo
-
Sandy JD, Verscharen C. Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo. Biochem J 2001;358:615-26.
-
(2001)
Biochem J
, vol.358
, pp. 615-626
-
-
Sandy, J.D.1
Verscharen, C.2
-
40
-
-
0036775227
-
Characterization of human aggrecanase 2 (ADAM-TS5): Substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4)
-
Tortorella MD, Liu RQ, Burn T, Newton RC, Arner E. Characterization of human aggrecanase 2 (ADAM-TS5): substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4). Matrix Biol 2002;21:499-511.
-
(2002)
Matrix Biol
, vol.21
, pp. 499-511
-
-
Tortorella, M.D.1
Liu, R.Q.2
Burn, T.3
Newton, R.C.4
Arner, E.5
-
41
-
-
0037231877
-
Induction of aggrecanase 1 (ADAM-TS4) by interleukin-1 occurs through activation of constitutively produced protein
-
Pratta MA, Scherle PA, Yang G, Liu RQ, Newton RC. Induction of aggrecanase 1 (ADAM-TS4) by interleukin-1 occurs through activation of constitutively produced protein. Arthritis Rheum 2003;48:119-33.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 119-133
-
-
Pratta, M.A.1
Scherle, P.A.2
Yang, G.3
Liu, R.Q.4
Newton, R.C.5
-
42
-
-
0037310889
-
Inhibition of disease progression by a novel retinoid antagonist in animal models of arthritis
-
Beehler BC, Hei YJ, Chen S, Lupisella JA, Ostrowski J, Starrett JE, et al. Inhibition of disease progression by a novel retinoid antagonist in animal models of arthritis. J Rheumatol 2003;30:355-63.
-
(2003)
J Rheumatol
, vol.30
, pp. 355-363
-
-
Beehler, B.C.1
Hei, Y.J.2
Chen, S.3
Lupisella, J.A.4
Ostrowski, J.5
Starrett, J.E.6
-
43
-
-
0020410817
-
Electron microscopic studies of cartilage proteoglycans: Direct evidence for the variable length of the chondroitin sulfate-rich region of proteoglycan subunit core protein
-
Buckwalter JA, Rosenberg LC. Electron microscopic studies of cartilage proteoglycans: direct evidence for the variable length of the chondroitin sulfate-rich region of proteoglycan subunit core protein. J Biol Chem 1982;257:9830-9.
-
(1982)
J Biol Chem
, vol.257
, pp. 9830-9839
-
-
Buckwalter, J.A.1
Rosenberg, L.C.2
-
44
-
-
0023393878
-
Extended and globular protein domains in cartilage proteoglycans
-
Paulsson M, Morgelin M, Wiedemann H, Beardmore-Gray M, Dunham D, Hardingham T, et al. Extended and globular protein domains in cartilage proteoglycans. Biochem J 1987;245:763-72.
-
(1987)
Biochem J
, vol.245
, pp. 763-772
-
-
Paulsson, M.1
Morgelin, M.2
Wiedemann, H.3
Beardmore-Gray, M.4
Dunham, D.5
Hardingham, T.6
-
45
-
-
0030069604
-
Age-related changes in the content of the C-terminal region of aggrecan in human articular cartilage
-
Dudhia J, Davidson CM, Wells TM, Vynios DH, Hardingham TE, Bayliss MT. Age-related changes in the content of the C-terminal region of aggrecan in human articular cartilage. Biochem J 1996;313:933-40.
-
(1996)
Biochem J
, vol.313
, pp. 933-940
-
-
Dudhia, J.1
Davidson, C.M.2
Wells, T.M.3
Vynios, D.H.4
Hardingham, T.E.5
Bayliss, M.T.6
-
46
-
-
0033520318
-
ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteinases
-
Hurskainen TL, Hirohata S, Seldin MF, Apte SS. ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteinases. J Biol Chem 1999;274:25555-63.
-
(1999)
J Biol Chem
, vol.274
, pp. 25555-25563
-
-
Hurskainen, T.L.1
Hirohata, S.2
Seldin, M.F.3
Apte, S.S.4
-
47
-
-
16244418694
-
Matrix metalloproteinases are not essential for aggrecan turnover during normal skeletal growth and development
-
Little CB, Meeker CT, Hembry RM, Sims NA, Lawlor KE, Golub SB, et al. Matrix metalloproteinases are not essential for aggrecan turnover during normal skeletal growth and development. Mol Cell Biol 2005;25:3388-99.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3388-3399
-
-
Little, C.B.1
Meeker, C.T.2
Hembry, R.M.3
Sims, N.A.4
Lawlor, K.E.5
Golub, S.B.6
-
49
-
-
0036499472
-
Hyaluronate degradation as an alternative mechanism for proteoglycan release from cartilage during interleukin-1β-stimulated catabolism
-
Sztrolovics R, Recklies AD, Roughley PJ, Mort JS. Hyaluronate degradation as an alternative mechanism for proteoglycan release from cartilage during interleukin-1β-stimulated catabolism. Biochem J 2002;362:473-9.
-
(2002)
Biochem J
, vol.362
, pp. 473-479
-
-
Sztrolovics, R.1
Recklies, A.D.2
Roughley, P.J.3
Mort, J.S.4
-
50
-
-
38049115682
-
Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice
-
Ilic MZ, East CJ, Rogerson FM, Fosang AJ, Handley CJ. Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice. J Biol Chem 2007;282:37420-8.
-
(2007)
J Biol Chem
, vol.282
, pp. 37420-37428
-
-
Ilic, M.Z.1
East, C.J.2
Rogerson, F.M.3
Fosang, A.J.4
Handley, C.J.5
|