-
2
-
-
34447119750
-
Mechanism of disease: Role of chondrocytes in the pathogenesis of osteoarthritis - Structure, chaos and senescence
-
Aigner T, Soder S, Gebhard PM, McAlinden A, Haag J,. Mechanism of disease: role of chondrocytes in the pathogenesis of osteoarthritis-structure, chaos and senescence. Nat Clin Pract Rheumatol 2007; 3: 391-9.
-
(2007)
Nat Clin Pract Rheumatol
, vol.3
, pp. 391-399
-
-
Aigner, T.1
Soder, S.2
Gebhard, P.M.3
McAlinden, A.4
Haag, J.5
-
4
-
-
0035076487
-
Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: Associations with degenerative changes
-
Tetlow LC, Adlam DJ, Woolley DE,. Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: associations with degenerative changes. Arthritis Rheum 2001; 44: 585-94.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 585-594
-
-
Tetlow, L.C.1
Adlam, D.J.2
Woolley, D.E.3
-
5
-
-
77951743715
-
MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes
-
Akhtar N, Rasheed Z, Ramamurthy S, Anbazhagan AN, Voss FR, Haqqi TM,. MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes. Arthritis Rheum 2010; 62: 1361-71.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1361-1371
-
-
Akhtar, N.1
Rasheed, Z.2
Ramamurthy, S.3
Anbazhagan, A.N.4
Voss, F.R.5
Haqqi, T.M.6
-
6
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP,. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
7
-
-
84864755975
-
MicroRNA-34a modulates MDM4 expression via a target site in the open reading frame
-
Mandke P, Wyatt N, Fraser J, Bates B, Berberich SJ, Markey MP,. MicroRNA-34a modulates MDM4 expression via a target site in the open reading frame. PLoS One 2012; 7: e42034.
-
(2012)
PLoS One
, vol.7
, pp. e42034
-
-
Mandke, P.1
Wyatt, N.2
Fraser, J.3
Bates, B.4
Berberich, S.J.5
Markey, M.P.6
-
8
-
-
34547441263
-
Target mRNAs are repressed as efficiently by microRNA binding sites in the 5′UTR as in the 3′UTR
-
Lytle JR, Yario TA, Steitz JA,. Target mRNAs are repressed as efficiently by microRNA binding sites in the 5′UTR as in the 3′UTR. Proc Natl Acad Sci U S A 2007; 104: 9667-72.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 9667-9672
-
-
Lytle, J.R.1
Yario, T.A.2
Steitz, J.A.3
-
9
-
-
79956154138
-
A mini-review: MicroRNA in arthritis
-
Nakasa T, Nagata Y, Yamasaki K, Ochi M,. A mini-review: microRNA in arthritis. Physiol Genomics 2011; 43: 566-70.
-
(2011)
Physiol Genomics
, vol.43
, pp. 566-570
-
-
Nakasa, T.1
Nagata, Y.2
Yamasaki, K.3
Ochi, M.4
-
10
-
-
84866100301
-
Macro view of microRNA function in osteoarthritis
-
Miyaki S, Asahara H,. Macro view of microRNA function in osteoarthritis. Nat Rev Rheumatol 2012; 8: 543-52.
-
(2012)
Nat Rev Rheumatol
, vol.8
, pp. 543-552
-
-
Miyaki, S.1
Asahara, H.2
-
11
-
-
84881343888
-
The role of microRNAs in osteoarthritis and chondrogenesis
-
[review]
-
Le LT, Swingler TE, Clark IM,. The role of microRNAs in osteoarthritis and chondrogenesis [review]. Arthritis Rheum 2013; 65: 1963-74.
-
(2013)
Arthritis Rheum
, vol.65
, pp. 1963-1974
-
-
Le, L.T.1
Swingler, T.E.2
Clark, I.M.3
-
12
-
-
84860918355
-
MicroRNA-199a∗ regulates the expression of cyclooxygenase-2 in human chondrocytes
-
Akhtar N, Haqqi TM,. MicroRNA-199a∗ regulates the expression of cyclooxygenase-2 in human chondrocytes. Ann Rheum Dis 2012; 71: 1073-80.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 1073-1080
-
-
Akhtar, N.1
Haqqi, T.M.2
-
13
-
-
0035135642
-
Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development
-
Chung UI, Schipani E, McMahon AP, Kronenberg HM,. Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. J Clin Invest 2001; 107: 295-304.
-
(2001)
J Clin Invest
, vol.107
, pp. 295-304
-
-
Chung, U.I.1
Schipani, E.2
McMahon, A.P.3
Kronenberg, H.M.4
-
14
-
-
79953161898
-
Hedgehog morphogen: From secretion to reception
-
Gallet A,. Hedgehog morphogen: from secretion to reception. Trends Cell Biol 2011; 21: 238-46.
-
(2011)
Trends Cell Biol
, vol.21
, pp. 238-246
-
-
Gallet, A.1
-
15
-
-
0035577854
-
Hedgehog signaling in animal development: Paradigms and principles
-
Ingham PW, McMahon AP,. Hedgehog signaling in animal development: paradigms and principles. Genes Dev 2001; 15: 3059-87.
-
(2001)
Genes Dev
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
16
-
-
0025156778
-
The GLI gene encodes a nuclear protein which binds specific sequences in the human genome
-
Kinzler KW, Vogelstein B,. The GLI gene encodes a nuclear protein which binds specific sequences in the human genome. Mol Cell Biol 1990; 10: 634-42.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 634-642
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
17
-
-
77953661272
-
The human glioma-associated oncogene homolog 1 (GLI1) family of transcription factors in gene regulation and diseases
-
Zhu H, Lo HW,. The human glioma-associated oncogene homolog 1 (GLI1) family of transcription factors in gene regulation and diseases. Curr Genomics 2010; 11: 238-45.
-
(2010)
Curr Genomics
, vol.11
, pp. 238-245
-
-
Zhu, H.1
Lo, H.W.2
-
18
-
-
71549136203
-
Modulating hedgehog signaling can attenuate the severity of osteoarthritis
-
Lin AC, Seeto BL, Bartoszko JM, Khoury MA, Whetstone H, Ho L,. Modulating hedgehog signaling can attenuate the severity of osteoarthritis. Nat Med 2009; 15: 1421-5.
-
(2009)
Nat Med
, vol.15
, pp. 1421-1425
-
-
Lin, A.C.1
Seeto, B.L.2
Bartoszko, J.M.3
Khoury, M.A.4
Whetstone, H.5
Ho, L.6
-
20
-
-
84897993912
-
MicroRNA-608 and microRNA-34a regulate chordoma malignancy by targeting EGFR, Bcl-xL and MET
-
Zhang Y, Schiff D, Park D, Abounader R,. MicroRNA-608 and microRNA-34a regulate chordoma malignancy by targeting EGFR, Bcl-xL and MET. PLoS One 2014; 9: e91546.
-
(2014)
PLoS One
, vol.9
, pp. e91546
-
-
Zhang, Y.1
Schiff, D.2
Park, D.3
Abounader, R.4
-
21
-
-
16844375144
-
Targeted expression of SHH affects chondrocyte differentiation, growth plate organization, and Sox9 expression
-
Tavella S, Biticchi R, Schito A, Minina E, Di Martino D, Pagano A, et al. Targeted expression of SHH affects chondrocyte differentiation, growth plate organization, and Sox9 expression. J Bone Miner Res 2004; 19: 1678-88.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1678-1688
-
-
Tavella, S.1
Biticchi, R.2
Schito, A.3
Minina, E.4
Di Martino, D.5
Pagano, A.6
-
22
-
-
0025802119
-
The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip
-
Altman R, Alarcon G, Appelrouth D, Bloch D, Borenstein D, Brandt K, et al. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. Arthritis Rheum 1991; 34: 505-14.
-
(1991)
Arthritis Rheum
, vol.34
, pp. 505-514
-
-
Altman, R.1
Alarcon, G.2
Appelrouth, D.3
Bloch, D.4
Borenstein, D.5
Brandt, K.6
-
23
-
-
0022465236
-
Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee
-
Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum 1986; 29: 1039-49.
-
(1986)
Arthritis Rheum
, vol.29
, pp. 1039-1049
-
-
Altman, R.1
Asch, E.2
Bloch, D.3
Bole, G.4
Borenstein, D.5
Brandt, K.6
-
24
-
-
46749111932
-
Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy
-
Mak KK, Kronenberg HM, Chuang PT, Mackem S, Yang Y,. Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy. Development 2008; 135: 1947-56.
-
(2008)
Development
, vol.135
, pp. 1947-1956
-
-
Mak, K.K.1
Kronenberg, H.M.2
Chuang, P.T.3
Mackem, S.4
Yang, Y.5
-
25
-
-
79952637781
-
Hypertrophic differentiation of chondrocytes in osteoarthritis: The developmental aspect of degenerative joint disorders
-
Dreier R,. Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders. Arthritis Res Ther 2010; 12: 216.
-
(2010)
Arthritis Res Ther
, vol.12
, pp. 216
-
-
Dreier, R.1
-
26
-
-
84862125851
-
Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage
-
Wei F, Zhou J, Wei X, Zhang J, Fleming BC, Terek R, et al. Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage. Osteoarthritis Cartilage 2012; 20: 755-63.
-
(2012)
Osteoarthritis Cartilage
, vol.20
, pp. 755-763
-
-
Wei, F.1
Zhou, J.2
Wei, X.3
Zhang, J.4
Fleming, B.C.5
Terek, R.6
-
27
-
-
84857232095
-
Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis
-
Ruiz-Heiland G, Horn A, Zerr P, Hofstetter W, Baum W, Stock M, et al. Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis. Ann Rheum Dis 2012; 71: 400-7.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 400-407
-
-
Ruiz-Heiland, G.1
Horn, A.2
Zerr, P.3
Hofstetter, W.4
Baum, W.5
Stock, M.6
-
28
-
-
84871974005
-
MMP13 is a critical target gene during the progression of osteoarthritis
-
Wang M, Sampson ER, Jin H, Li J, Ke QH, Im HJ, et al. MMP13 is a critical target gene during the progression of osteoarthritis. Arthritis Res Ther 2013; 15: R5.
-
(2013)
Arthritis Res Ther
, vol.15
, pp. R5
-
-
Wang, M.1
Sampson, E.R.2
Jin, H.3
Li, J.4
Ke, Q.H.5
Im, H.J.6
-
29
-
-
15844413814
-
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
-
Glasson SS, Askew R, Sheppard B, Carito B, Blanchet T, Ma HL, et al. Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature 2005; 434: 644-8.
-
(2005)
Nature
, vol.434
, pp. 644-648
-
-
Glasson, S.S.1
Askew, R.2
Sheppard, B.3
Carito, B.4
Blanchet, T.5
Ma, H.L.6
-
30
-
-
79151483757
-
Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells
-
Tetsunaga T, Nishida K, Furumatsu T, Naruse K, Hirohata S, Yoshida A, et al. Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells. Osteoarthritis Cartilage 2011; 19: 222-32.
-
(2011)
Osteoarthritis Cartilage
, vol.19
, pp. 222-232
-
-
Tetsunaga, T.1
Nishida, K.2
Furumatsu, T.3
Naruse, K.4
Hirohata, S.5
Yoshida, A.6
-
31
-
-
84872149479
-
Sonic hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer
-
Chen JS, Huang XH, Wang Q, Huang JQ, Zhang LJ, Chen XL, et al. Sonic hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer. Carcinogenesis 2013; 34: 10-9.
-
(2013)
Carcinogenesis
, vol.34
, pp. 10-19
-
-
Chen, J.S.1
Huang, X.H.2
Wang, Q.3
Huang, J.Q.4
Zhang, L.J.5
Chen, X.L.6
-
32
-
-
81155126047
-
Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer
-
Yoo YA, Kang MH, Lee HJ, Kim BH, Park JK, Kim HK, et al. Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer. Cancer Res 2011; 71: 7061-70.
-
(2011)
Cancer Res
, vol.71
, pp. 7061-7070
-
-
Yoo, Y.A.1
Kang, M.H.2
Lee, H.J.3
Kim, B.H.4
Park, J.K.5
Kim, H.K.6
-
33
-
-
33745813856
-
The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells
-
Tuddenham L, Wheeler G, Ntounia-Fousara S, Waters J, Hajihosseini MK, Clark I, et al. The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells. FEBS Lett 2006; 580: 4214-7.
-
(2006)
FEBS Lett
, vol.580
, pp. 4214-4217
-
-
Tuddenham, L.1
Wheeler, G.2
Ntounia-Fousara, S.3
Waters, J.4
Hajihosseini, M.K.5
Clark, I.6
-
34
-
-
84891747233
-
Overexpression of hsa-miR-148a promotes cartilage production and inhibits cartilage degradation by osteoarthritic chondrocytes
-
Vonk LA, Kragten AH, Dhert WJ, Saris DB, Creemers LB,. Overexpression of hsa-miR-148a promotes cartilage production and inhibits cartilage degradation by osteoarthritic chondrocytes. Osteoarthritis Cartilage 2014; 22: 145-53.
-
(2014)
Osteoarthritis Cartilage
, vol.22
, pp. 145-153
-
-
Vonk, L.A.1
Kragten, A.H.2
Dhert, W.J.3
Saris, D.B.4
Creemers, L.B.5
-
35
-
-
32844470804
-
Repeated mechanical loading enhances the expression of Indian hedgehog in condylar cartilage
-
Ng TC, Chiu KW, Rabie AB, Hagg U,. Repeated mechanical loading enhances the expression of Indian hedgehog in condylar cartilage. Front Biosci 2006; 11: 943-8.
-
(2006)
Front Biosci
, vol.11
, pp. 943-948
-
-
Ng, T.C.1
Chiu, K.W.2
Rabie, A.B.3
Hagg, U.4
-
36
-
-
82655181357
-
MiR-365: A mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4
-
Guan YJ, Yang X, Wei L, Chen Q,. MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4. FASEB J 2011; 25: 4457-66.
-
(2011)
FASEB J
, vol.25
, pp. 4457-4466
-
-
Guan, Y.J.1
Yang, X.2
Wei, L.3
Chen, Q.4
-
37
-
-
84889036617
-
MicroRNA-127-5p regulates matrix metalloproteinase 13 expression and interleukin-1β-induced catabolic effects in human chondrocytes
-
Park SJ, Cheon EJ, Lee MH, Kim HA,. MicroRNA-127-5p regulates matrix metalloproteinase 13 expression and interleukin-1β-induced catabolic effects in human chondrocytes. Arthritis Rheum 2013; 65: 3141-52.
-
(2013)
Arthritis Rheum
, vol.65
, pp. 3141-3152
-
-
Park, S.J.1
Cheon, E.J.2
Lee, M.H.3
Kim, H.A.4
-
38
-
-
42449086421
-
MiR-148 targets human DNMT3b protein coding region
-
Duursma AM, Kedde M, Schrier M, le Sage C, Agami R,. miR-148 targets human DNMT3b protein coding region. RNA 2008; 14: 872-7.
-
(2008)
RNA
, vol.14
, pp. 872-877
-
-
Duursma, A.M.1
Kedde, M.2
Schrier, M.3
Le Sage, C.4
Agami, R.5
-
39
-
-
77951157723
-
MicroRNAs regulate human hepatocyte nuclear factor 4a, modulating the expression of metabolic enzymes and cell cycle
-
Takagi S, Nakajima M, Kida K, Yamaura Y, Fukami T, Yokoi T,. MicroRNAs regulate human hepatocyte nuclear factor 4a, modulating the expression of metabolic enzymes and cell cycle. J Biol Chem 2010; 285: 4415-22.
-
(2010)
J Biol Chem
, vol.285
, pp. 4415-4422
-
-
Takagi, S.1
Nakajima, M.2
Kida, K.3
Yamaura, Y.4
Fukami, T.5
Yokoi, T.6
-
40
-
-
57349183076
-
The interleukin 1β pathway in the pathogenesis of osteoarthritis
-
Daheshia M, Yao JQ,. The interleukin 1β pathway in the pathogenesis of osteoarthritis. J Rheumatol 2008; 35: 2306-12.
-
(2008)
J Rheumatol
, vol.35
, pp. 2306-2312
-
-
Daheshia, M.1
Yao, J.Q.2
-
41
-
-
78650983649
-
Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
-
Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H,. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 2011; 7: 33-42.
-
(2011)
Nat Rev Rheumatol
, vol.7
, pp. 33-42
-
-
Kapoor, M.1
Martel-Pelletier, J.2
Lajeunesse, D.3
Pelletier, J.P.4
Fahmi, H.5
-
42
-
-
84862507068
-
Upregulation of miR-31∗ is negatively associated with recurrent/newly formed oral leukoplakia
-
Xiao W, Bao ZX, Zhang CY, Zhang XY, Shi LJ, Zhou ZT, et al. Upregulation of miR-31∗ is negatively associated with recurrent/newly formed oral leukoplakia. PLoS One 2012; 7: e38648.
-
(2012)
PLoS One
, vol.7
, pp. e38648
-
-
Xiao, W.1
Bao, Z.X.2
Zhang, C.Y.3
Zhang, X.Y.4
Shi, L.J.5
Zhou, Z.T.6
-
43
-
-
84892428246
-
Bcl-xL silencing induces alterations in hsa-miR-608 expression and subsequent cell death in A549 and SK-LU1 human lung adenocarcinoma cells
-
Othman N, In LL, Harikrishna JA, Hasima N,. Bcl-xL silencing induces alterations in hsa-miR-608 expression and subsequent cell death in A549 and SK-LU1 human lung adenocarcinoma cells. PLoS One 2013; 8: e81735.
-
(2013)
PLoS One
, vol.8
, pp. e81735
-
-
Othman, N.1
In, L.L.2
Harikrishna, J.A.3
Hasima, N.4
-
44
-
-
80052416538
-
Differentially expressed microRNAs in human oocytes
-
Xu YW, Wang B, Ding CH, Li T, Gu F, Zhou C,. Differentially expressed microRNAs in human oocytes. J Assist Reprod Genet 2011; 28: 559-66.
-
(2011)
J Assist Reprod Genet
, vol.28
, pp. 559-566
-
-
Xu, Y.W.1
Wang, B.2
Ding, C.H.3
Li, T.4
Gu, F.5
Zhou, C.6
|