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Volumn 5, Issue 8, 2015, Pages 806-821

Evolutionary determinants of cancer

Author keywords

[No Author keywords available]

Indexed keywords

CANCER RISK; CANCER STEM CELL; CELL RENEWAL; CHROMOSOMAL INSTABILITY; CLONAL EVOLUTION; ECOSYSTEM RESILIENCE; EPIGENETICS; EVOLUTIONARY ADAPTATION; GENE DELETION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; INTRACELLULAR SIGNALING; LONGEVITY; NEOPLASM; NONHUMAN; PHYLOGENOMICS; PLASTICITY; REVIEW; SIGNAL TRANSDUCTION; XENOTRANSPLANTATION; METABOLISM; MOLECULAR EVOLUTION; NEOPLASMS; RISK;

EID: 84938773709     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-15-0439     Document Type: Review
Times cited : (337)

References (201)
  • 2
    • 84875145218 scopus 로고    scopus 로고
    • Addressing the growing international challenge of cancer: A multinational perspective
    • 175cm2
    • Varmus H, Kumar HS. Addressing the growing international challenge of cancer: a multinational perspective. Sci Transl Med 2013;5:175cm2.
    • (2013) Sci Transl Med , vol.5
    • Varmus, H.1    Kumar, H.S.2
  • 3
    • 84964240053 scopus 로고    scopus 로고
    • Biological and therapeutic impact of intratumor heterogeneity in cancer evolution
    • McGranahan N, Swanton C. Biological and therapeutic impact of intratumor heterogeneity in cancer evolution. Cancer Cell 2015;27:15-26.
    • (2015) Cancer Cell , vol.27 , pp. 15-26
    • McGranahan, N.1    Swanton, C.2
  • 4
    • 84874354257 scopus 로고    scopus 로고
    • The implications of clonal genome evolution for cancer medicine
    • Aparicio S, Caldas C. The implications of clonal genome evolution for cancer medicine. N Engl J Med 2013;368:842-51.
    • (2013) N Engl J Med , vol.368 , pp. 842-851
    • Aparicio, S.1    Caldas, C.2
  • 6
    • 0002781901 scopus 로고
    • The natural history of cancer
    • Foulds L. The natural history of cancer. J Chronic Dis 1958;8:2-37.
    • (1958) J Chronic Dis , vol.8 , pp. 2-37
    • Foulds, L.1
  • 7
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC. The clonal evolution of tumor cell populations. Science 1976;194:23-8.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 8
    • 0016692602 scopus 로고
    • Mutation selection and the natural history of cancer
    • Greaves
    • Cairns J. Mutation selection and the natural history of cancer. Nature 1975;255:197-200. Greaves
    • (1975) Nature , vol.255 , pp. 197-200
    • Cairns, J.1
  • 9
    • 84867744264 scopus 로고    scopus 로고
    • Evolution of the cancer genome
    • Yates LR, Campbell PJ. Evolution of the cancer genome. Nat Rev Genet 2012;13:795-806.
    • (2012) Nat Rev Genet , vol.13 , pp. 795-806
    • Yates, L.R.1    Campbell, P.J.2
  • 11
    • 84895876130 scopus 로고    scopus 로고
    • Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
    • Gerlinger M, Horswell S, Larkin J, Rowan AJ, Salm MP, Varela I, et al. Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing. Nat Genet 2014;46:225-33.
    • (2014) Nat Genet , vol.46 , pp. 225-233
    • Gerlinger, M.1    Horswell, S.2    Larkin, J.3    Rowan, A.J.4    Salm, M.P.5    Varela, I.6
  • 12
    • 42949150219 scopus 로고    scopus 로고
    • Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer
    • Stoecklein NH, Hosch SB, Bezler M, Stern F, Hartmann CH, Vay C, et al. Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer. Cancer Cell 2008;13:441-53.
    • (2008) Cancer Cell , vol.13 , pp. 441-453
    • Stoecklein, N.H.1    Hosch, S.B.2    Bezler, M.3    Stern, F.4    Hartmann, C.H.5    Vay, C.6
  • 13
    • 78751644099 scopus 로고    scopus 로고
    • Genetic variegation of clonal architecture and propagating cells in leukaemia
    • Anderson K, Lutz C, van Delft FW, Bateman CM, Guo Y, Colman SM, et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 2011;469:356-61.
    • (2011) Nature , vol.469 , pp. 356-361
    • Anderson, K.1    Lutz, C.2    Van Delft, F.W.3    Bateman, C.M.4    Guo, Y.5    Colman, S.M.6
  • 15
    • 84921415076 scopus 로고    scopus 로고
    • Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
    • Meyer M, Reimand J, Lan X, Head R, Zhu X, Kushida M, et al. Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity. Proc Natl Acad Sci U S A 2015;112:851-6.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. 851-856
    • Meyer, M.1    Reimand, J.2    Lan, X.3    Head, R.4    Zhu, X.5    Kushida, M.6
  • 16
    • 84906238686 scopus 로고    scopus 로고
    • Clonal evolution in breast cancer revealed by single nucleus genome sequencing
    • Wang Y, Waters J, Leung ML, Unruh A, Roh W, Shi X, et al. Clonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature 2014;512:155-60.
    • (2014) Nature , vol.512 , pp. 155-160
    • Wang, Y.1    Waters, J.2    Leung, M.L.3    Unruh, A.4    Roh, W.5    Shi, X.6
  • 18
    • 84864880991 scopus 로고    scopus 로고
    • Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
    • Ramskold D, Luo S, Wang YC, Li R, Deng Q, Faridani OR, et al. Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells. Nat Biotechnol 2012;30:777-82.
    • (2012) Nat Biotechnol , vol.30 , pp. 777-782
    • Ramskold, D.1    Luo, S.2    Wang, Y.C.3    Li, R.4    Deng, Q.5    Faridani, O.R.6
  • 20
    • 17744394753 scopus 로고    scopus 로고
    • Phylogenomics and the reconstruction of the tree of life
    • Delsuc F, Brinkmann H, Philippe H. Phylogenomics and the reconstruction of the tree of life. Nat Rev Genet 2005;6:361-75.
    • (2005) Nat Rev Genet , vol.6 , pp. 361-375
    • Delsuc, F.1    Brinkmann, H.2    Philippe, H.3
  • 22
    • 78049398107 scopus 로고    scopus 로고
    • Distant metastasis occurs late during the genetic evolution of pancreatic cancer
    • Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 2010;467:1114-7.
    • (2010) Nature , vol.467 , pp. 1114-1117
    • Yachida, S.1    Jones, S.2    Bozic, I.3    Antal, T.4    Leary, R.5    Fu, B.6
  • 24
    • 84877579861 scopus 로고    scopus 로고
    • Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
    • Murtaza M, Dawson S-J, Tsui DWY, Gale D, Forshew T, Piskorz AM, et al. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature 2013;497:108-12.
    • (2013) Nature , vol.497 , pp. 108-112
    • Murtaza, M.1    Dawson, S.-J.2    Tsui, D.3    Gale, D.4    Forshew, T.5    Piskorz, A.M.6
  • 27
    • 84907855592 scopus 로고    scopus 로고
    • Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
    • de Bruin EC, McGranahan N, Mitter R, Salm M, Wedge DC, Yates L, et al. Spatial and temporal diversity in genomic instability processes defines lung cancer evolution. Science 2014;346:251-6.
    • (2014) Science , vol.346 , pp. 251-256
    • De Bruin, E.C.1    McGranahan, N.2    Mitter, R.3    Salm, M.4    Wedge, D.C.5    Yates, L.6
  • 28
    • 84876920984 scopus 로고    scopus 로고
    • Developmental timing of mutations revealed by wholegenome sequencing of twins with acute lymphoblastic leukemia
    • Ma Y, Dobbins SE, Sherborne AL, Chubb D, Galbiati M, Cazzaniga G, et al. Developmental timing of mutations revealed by wholegenome sequencing of twins with acute lymphoblastic leukemia. Proc Natl Acad Sci U S A 2013;110:7429-33.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 7429-7433
    • Ma, Y.1    Dobbins, S.E.2    Sherborne, A.L.3    Chubb, D.4    Galbiati, M.5    Cazzaniga, G.6
  • 29
    • 38349183668 scopus 로고    scopus 로고
    • Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia
    • Hong D, Gupta R, Ancliffe P, Atzberger A, Brown J, Soneji S, et al. Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia. Science 2008;319:336-9.
    • (2008) Science , vol.319 , pp. 336-339
    • Hong, D.1    Gupta, R.2    Ancliffe, P.3    Atzberger, A.4    Brown, J.5    Soneji, S.6
  • 30
    • 0141482011 scopus 로고    scopus 로고
    • Leukemia in twins: Lessons in natural history
    • Greaves MF, Maia AT, Wiemels JL, Ford AM. Leukemia in twins: lessons in natural history. Blood 2003;102:2321-33.
    • (2003) Blood , vol.102 , pp. 2321-2333
    • Greaves, M.F.1    Maia, A.T.2    Wiemels, J.L.3    Ford, A.M.4
  • 31
    • 84894245627 scopus 로고    scopus 로고
    • Identifi cation of pre-leukaemic haematopoietic stem cells in acute leukaemia
    • Shlush LI, Zandi S, Mitchell A, Chen WC, Brandwein JM, Gupta V, et al. Identifi cation of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature 2014;506:328-33.
    • (2014) Nature , vol.506 , pp. 328-333
    • Shlush, L.I.1    Zandi, S.2    Mitchell, A.3    Chen, W.C.4    Brandwein, J.M.5    Gupta, V.6
  • 32
    • 85032131319 scopus 로고
    • Punctuated equilibria: The tempo and mode of evolution reconsidered
    • Gould SJ, Eldridge N. Punctuated equilibria: the tempo and mode of evolution reconsidered. Paleobiol 1977;3:115-51.
    • (1977) Paleobiol , vol.3 , pp. 115-151
    • Gould, S.J.1    Eldridge, N.2
  • 34
    • 84923989372 scopus 로고    scopus 로고
    • Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
    • Shlien A, Campbell BB, de Borja R, Alexandrov LB, Merico D, Wedge D, et al. Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers. Nat Genet 2015;47:257-62.
    • (2015) Nat Genet , vol.47 , pp. 257-262
    • Shlien, A.1    Campbell, B.B.2    De Borja, R.3    Alexandrov, L.B.4    Merico, D.5    Wedge, D.6
  • 35
    • 78650959663 scopus 로고    scopus 로고
    • Massive genomic rearrangement acquired in a single catastrophic event during cancer development
    • Stephens PJ, Greenman CD, Fu B, Yang F, Bignell GR, Mudie LJ, et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 2011;144:27-40.
    • (2011) Cell , vol.144 , pp. 27-40
    • Stephens, P.J.1    Greenman, C.D.2    Fu, B.3    Yang, F.4    Bignell, G.R.5    Mudie, L.J.6
  • 36
  • 40
    • 70350716805 scopus 로고    scopus 로고
    • Ecological therapy for cancer: Defining tumors using an ecosystem paradigm suggests new opportunities for novel cancer treatments
    • Pienta KJ, McGregor N, Axelrod R, Axelrod DE. Ecological therapy for cancer: defining tumors using an ecosystem paradigm suggests new opportunities for novel cancer treatments. Transl Oncol 2008;1:158-64.
    • (2008) Transl Oncol , vol.1 , pp. 158-164
    • Pienta, K.J.1    McGregor, N.2    Axelrod, R.3    Axelrod, D.E.4
  • 41
    • 37549013776 scopus 로고    scopus 로고
    • A microenvironmental model of carcinogenesis
    • Gatenby RA, Gillies RJ. A microenvironmental model of carcinogenesis. Nat Rev Cancer 2008;8:56-61.
    • (2008) Nat Rev Cancer , vol.8 , pp. 56-61
    • Gatenby, R.A.1    Gillies, R.J.2
  • 42
    • 84856013431 scopus 로고    scopus 로고
    • Clonal evolution in cancer
    • Greaves M, Maley CC. Clonal evolution in cancer. Nature 2012;481: 306-13.
    • (2012) Nature , vol.481 , pp. 306-313
    • Greaves, M.1    Maley, C.C.2
  • 45
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 46
    • 78651405693 scopus 로고    scopus 로고
    • Sun-induced nonsynonymous p53 mutations are extensively accumulated and tolerated in normal appearing human skin
    • Ståhl PL, Stranneheim H, Asplund A, Berglund L, Pontén F, Lundeberg J. Sun-induced nonsynonymous p53 mutations are extensively accumulated and tolerated in normal appearing human skin. J Invest Dermatol 2011;131:504-8.
    • (2011) J Invest Dermatol , vol.131 , pp. 504-508
    • Ståhl, P.L.1    Stranneheim, H.2    Asplund, A.3    Berglund, L.4    Pontén, F.5    Lundeberg, J.6
  • 47
    • 84925518008 scopus 로고    scopus 로고
    • Role of TP53 mutations in the origin and evolution of therapy related acute myeloid leukaemia
    • Wong TN, Ramsingh G, Young AL, Miller CA, Touma W, Welch JS, et al. Role of TP53 mutations in the origin and evolution of therapy related acute myeloid leukaemia. Nature 2015;518:552-5.
    • (2015) Nature , vol.518 , pp. 552-555
    • Wong, T.N.1    Ramsingh, G.2    Young, A.L.3    Miller, C.A.4    Touma, W.5    Welch, J.S.6
  • 48
    • 84921755945 scopus 로고    scopus 로고
    • Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells
    • Bartesaghi S, Graziano V, Galavotti S, Henriquez NV, Betts J, Saxena J, et al. Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells. Proc Natl Acad Sci USA 2015;112:1059-64.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 1059-1064
    • Bartesaghi, S.1    Graziano, V.2    Galavotti, S.3    Henriquez, N.V.4    Betts, J.5    Saxena, J.6
  • 50
    • 70749101076 scopus 로고    scopus 로고
    • Steroid hormone receptors in prostate cancer: A hard habit to break?
    • Attard G, Cooper CS, de Bono JS. Steroid hormone receptors in prostate cancer: a hard habit to break? Cancer Cell 2009;16:458-62.
    • (2009) Cancer Cell , vol.16 , pp. 458-462
    • Attard, G.1    Cooper, C.S.2    De Bono, J.S.3
  • 51
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by BCRABL gene mutation or amplification
    • Gorre ME, Mohammed M, Ellwood K, Hsu N, Paquette R, Rao PN, et al. Clinical resistance to STI-571 cancer therapy caused by BCRABL gene mutation or amplification. Science 2001;293:876-80.
    • (2001) Science , vol.293 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3    Hsu, N.4    Paquette, R.5    Rao, P.N.6
  • 54
    • 84923358817 scopus 로고    scopus 로고
    • Cell-of-origin chromatin organization shapes the mutational landscape of cancer
    • Polak P, Karlic R, Koren A, Thurman R, Sandstrom R, Lawrence MS, et al. Cell-of-origin chromatin organization shapes the mutational landscape of cancer. Nature 2015;518:360-4.
    • (2015) Nature , vol.518 , pp. 360-364
    • Polak, P.1    Karlic, R.2    Koren, A.3    Thurman, R.4    Sandstrom, R.5    Lawrence, M.S.6
  • 56
    • 77955911497 scopus 로고    scopus 로고
    • Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma
    • Inda MM, Bonavia R, Mukasa A, Narita Y, Sah DW, Vandenberg S, et al. Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma. Genes Dev 2010;24:1731-45.
    • (2010) Genes Dev , vol.24 , pp. 1731-1745
    • Inda, M.M.1    Bonavia, R.2    Mukasa, A.3    Narita, Y.4    Sah, D.W.5    Vandenberg, S.6
  • 57
    • 84922681704 scopus 로고    scopus 로고
    • Heterogeneity for IGF-II production maintained by public goods dynamics in neuroendocrine pancreatic cancer
    • Archetti M, Ferraro DA, Christofori G. Heterogeneity for IGF-II production maintained by public goods dynamics in neuroendocrine pancreatic cancer. Proc Natl Acad Sci U S A 2015;112:1833-8.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. 1833-1838
    • Archetti, M.1    Ferraro, D.A.2    Christofori, G.3
  • 58
    • 84884365015 scopus 로고    scopus 로고
    • The causes and consequences of genetic heterogeneity in cancer evolution
    • Burrell RA, McGranahan N, Bartek J, Swanton C. The causes and consequences of genetic heterogeneity in cancer evolution. Nature 2013;501:338-45.
    • (2013) Nature , vol.501 , pp. 338-345
    • Burrell, R.A.1    McGranahan, N.2    Bartek, J.3    Swanton, C.4
  • 59
    • 84884369881 scopus 로고    scopus 로고
    • Selection and adaptation during metastatic cancer progression
    • Klein CA. Selection and adaptation during metastatic cancer progression. Nature 2013;501:365-72.
    • (2013) Nature , vol.501 , pp. 365-372
    • Klein, C.A.1
  • 61
    • 77949773695 scopus 로고    scopus 로고
    • Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal
    • Sotillo R, Schvartzman JM, Socci ND, Benezra R. Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal. Nature 2010;464:436-40.
    • (2010) Nature , vol.464 , pp. 436-440
    • Sotillo, R.1    Schvartzman, J.M.2    Socci, N.D.3    Benezra, R.4
  • 63
    • 84897376269 scopus 로고    scopus 로고
    • Does everyone develop covert cancer?
    • Greaves M. Does everyone develop covert cancer? Nat Rev Cancer 2014;14:209-10.
    • (2014) Nat Rev Cancer , vol.14 , pp. 209-210
    • Greaves, M.1
  • 65
    • 84929991442 scopus 로고    scopus 로고
    • Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin
    • Martincorena I, Roshan A, Gerstung M, Ellis P, Van Loo P, McLaren S, et al. Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin. Science 015;348:880-6.
    • Science 015 , vol.348 , pp. 880-886
    • Martincorena, I.1    Roshan, A.2    Gerstung, M.3    Ellis, P.4    Van Loo, P.5    McLaren, S.6
  • 66
    • 0842288340 scopus 로고    scopus 로고
    • Evolutionary dynamics of biological games
    • Nowak MA, Sigmund K. Evolutionary dynamics of biological games. Science 2004;303:793-9.
    • (2004) Science , vol.303 , pp. 793-799
    • Nowak, M.A.1    Sigmund, K.2
  • 68
    • 39749086288 scopus 로고    scopus 로고
    • Integrative mathematical oncology
    • Anderson AR, Quaranta V. Integrative mathematical oncology. Nat Rev Cancer 2008;8:227-34.
    • (2008) Nat Rev Cancer , vol.8 , pp. 227-234
    • Anderson, A.R.1    Quaranta, V.2
  • 69
    • 24944468183 scopus 로고    scopus 로고
    • Evolutionary biology of cancer
    • Crespi B, Summers K. Evolutionary biology of cancer. Trends Ecol Evol 2005;20:545-52.
    • (2005) Trends Ecol Evol , vol.20 , pp. 545-552
    • Crespi, B.1    Summers, K.2
  • 70
    • 84873084388 scopus 로고    scopus 로고
    • Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer
    • Kreso A, O’Brien CA, van Galen P, Gan OI, Notta F, Brown AM, et al. Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer. Science 2013;339:543-8.
    • (2013) Science , vol.339 , pp. 543-548
    • Kreso, A.1    O’Brien, C.A.2    Van Galen, P.3    Gan, O.I.4    Notta, F.5    Brown, A.M.6
  • 71
    • 0029795904 scopus 로고    scopus 로고
    • Cancer as a complex adaptive system
    • Schwab ED, Pienta KJ. Cancer as a complex adaptive system. Med Hypotheses 1996;47:235-41.
    • (1996) Med Hypotheses , vol.47 , pp. 235-241
    • Schwab, E.D.1    Pienta, K.J.2
  • 72
    • 7644238181 scopus 로고    scopus 로고
    • Biological robustness
    • Kitano H. Biological robustness. Nat Rev Genet 2004;5:826-37.
    • (2004) Nat Rev Genet , vol.5 , pp. 826-837
    • Kitano, H.1
  • 74
    • 79955483094 scopus 로고    scopus 로고
    • Design principles of adaptive immune systems
    • Boehm T. Design principles of adaptive immune systems. Nat Rev Immunol 2011;11:307-17.
    • (2011) Nat Rev Immunol , vol.11 , pp. 307-317
    • Boehm, T.1
  • 75
    • 1542619848 scopus 로고    scopus 로고
    • Cancer as a robust system: Implications for anticancer therapy
    • Kitano H. Cancer as a robust system: implications for anticancer therapy. Nat Rev Cancer 2004;4:227-35.
    • (2004) Nat Rev Cancer , vol.4 , pp. 227-235
    • Kitano, H.1
  • 80
    • 84863000299 scopus 로고    scopus 로고
    • The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
    • Diaz LA Jr, Williams RT, Wu J, Kinde I, Hecht JR, Berlin J, et al. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature 2012;486:537-40.
    • (2012) Nature , vol.486 , pp. 537-540
    • Diaz, L.A.1    Williams, R.T.2    Wu, J.3    Kinde, I.4    Hecht, J.R.5    Berlin, J.6
  • 81
    • 34547221085 scopus 로고    scopus 로고
    • Kinase domain mutations of BCR-ABL frequently precede imatinib-based therapy and give rise to relapse in patients with de novo Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL)
    • Pfeifer H, Wassmann B, Pavlova A, Wunderle L, Oldenburg J, Binckebanck A, et al. Kinase domain mutations of BCR-ABL frequently precede imatinib-based therapy and give rise to relapse in patients with de novo Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL). Blood 2007;110:727-34.
    • (2007) Blood , vol.110 , pp. 727-734
    • Pfeifer, H.1    Wassmann, B.2    Pavlova, A.3    Wunderle, L.4    Oldenburg, J.5    Binckebanck, A.6
  • 82
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer 2007;7:834-46.
    • (2007) Nat Rev Cancer , vol.7 , pp. 834-846
    • Aguirre-Ghiso, J.A.1
  • 83
    • 33845607284 scopus 로고    scopus 로고
    • Persister cells, dormancy and infectious disease
    • Lewis K. Persister cells, dormancy and infectious disease. Nat Rev Microbiol 2007;5:48-56.
    • (2007) Nat Rev Microbiol , vol.5 , pp. 48-56
    • Lewis, K.1
  • 84
    • 56549128268 scopus 로고    scopus 로고
    • Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
    • Wilson A, Laurenti E, Oser G, van der Wath RC, Blanco-Bose W, Jaworski M, et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 2008;135:1118-29.
    • (2008) Cell , vol.135 , pp. 1118-1129
    • Wilson, A.1    Laurenti, E.2    Oser, G.3    Van Der Wath, R.C.4    Blanco-Bose, W.5    Jaworski, M.6
  • 86
    • 84864286442 scopus 로고    scopus 로고
    • Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
    • Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature 2012;487:505-9.
    • (2012) Nature , vol.487 , pp. 505-509
    • Wilson, T.R.1    Fridlyand, J.2    Yan, Y.3    Penuel, E.4    Burton, L.5    Chan, E.6
  • 87
    • 84864285794 scopus 로고    scopus 로고
    • Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
    • Straussman R, Morikawa T, Shee K, Barzily-Rokni M, Qian ZR, Du J, et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature 2012;487:500-4.
    • (2012) Nature , vol.487 , pp. 500-504
    • Straussman, R.1    Morikawa, T.2    Shee, K.3    Barzily-Rokni, M.4    Qian, Z.R.5    Du, J.6
  • 90
    • 84907487414 scopus 로고    scopus 로고
    • Nusse R. Stem cell signaling. An integral pro- gram for tissue renewal and regeneration: Wnt signaling and stem cell control
    • Clevers H, Loh KM, Nusse R. Stem cell signaling. An integral pro- gram for tissue renewal and regeneration: Wnt signaling and stem cell control. Science 2014;346:1248012.
    • (2014) Science , vol.346
    • Clevers, H.1    Loh, K.M.2
  • 91
    • 65449182840 scopus 로고    scopus 로고
    • Hydra and the evolution of stem cells
    • Bosch TC. Hydra and the evolution of stem cells. Bioessays 2009;31: 478-86.
    • (2009) Bioessays , vol.31 , pp. 478-486
    • Bosch, T.C.1
  • 92
    • 84866161950 scopus 로고    scopus 로고
    • Cellular hyperproliferation and cancer as evolutionary variables
    • Sanchez Alvarado A. Cellular hyperproliferation and cancer as evolutionary variables. Curr Biol 2012;22:R772-8.
    • (2012) Curr Biol , vol.22 , pp. R772-R778
    • Sanchez Alvarado, A.1
  • 93
  • 94
    • 70349123829 scopus 로고    scopus 로고
    • The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells
    • Cicalese A, Bonizzi G, Pasi CE, Faretta M, Ronzoni S, Giulini B, et al. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. Cell 2009;138:1083-95.
    • (2009) Cell , vol.138 , pp. 1083-1095
    • Cicalese, A.1    Bonizzi, G.2    Pasi, C.E.3    Faretta, M.4    Ronzoni, S.5    Giulini, B.6
  • 96
    • 84879736910 scopus 로고    scopus 로고
    • Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution
    • Humphries A, Cereser B, Gay LJ, Miller DS, Das B, Gutteridge A, et al. Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution. Proc Natl Acad Sci U S A 2013;110:E2490-9.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. E2490-E2499
    • Humphries, A.1    Cereser, B.2    Gay, L.J.3    Miller, D.S.4    Das, B.5    Gutteridge, A.6
  • 98
    • 84896125494 scopus 로고    scopus 로고
    • Evolution of the cancer stem cell model
    • Kreso A, Dick JE. Evolution of the cancer stem cell model. Cell Stem Cell2 014;14:275-91.
    • Cell Stem Cell2 014 , vol.14 , pp. 275-291
    • Kreso, A.1    Dick, J.E.2
  • 100
    • 69449096005 scopus 로고    scopus 로고
    • Heterogeneity in cancer: Cancer stem cells versus clonal evolution
    • Shackleton M, Quintana E, Fearon ER, Morrison SJ. Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell 2009;138:822-9
    • (2009) Cell , vol.138 , pp. 822-829
    • Shackleton, M.1    Quintana, E.2    Fearon, E.R.3    Morrison, S.J.4
  • 101
    • 84872825418 scopus 로고    scopus 로고
    • Cancer stem cells as ‘units of selection’
    • Greaves M. Cancer stem cells as ‘units of selection’. Evol Appl 2013;6:102-8.
    • (2013) Evol Appl , vol.6 , pp. 102-108
    • Greaves, M.1
  • 102
    • 0034534370 scopus 로고    scopus 로고
    • A critical approach to the definition of Darwinian units of selection
    • Rinkevich B. A critical approach to the definition of Darwinian units of selection. Biol Bull 2000;199:231-40.
    • (2000) Biol Bull , vol.199 , pp. 231-240
    • Rinkevich, B.1
  • 104
    • 0004236135 scopus 로고
    • Princeton, New Jersey: Princeton University Press
    • Buss LW. The evolution of individuality. Princeton, New Jersey: Princeton University Press; 1987.
    • (1987) The Evolution of Individuality
    • Buss, L.W.1
  • 106
    • 42449091900 scopus 로고    scopus 로고
    • Genetic royal cheats in leaf-cutting ant societies
    • Hughes WO, Boomsma JJ. Genetic royal cheats in leaf-cutting ant societies. Proc Natl Acad Sci U S A 2008;105:5150-3.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 5150-5153
    • Hughes, W.O.1    Boomsma, J.J.2
  • 109
    • 0029866975 scopus 로고    scopus 로고
    • Tumour progression: Random mutations or an integrated survival response to cellular stress conserved from unicellular organisms?
    • Israel L. Tumour progression: random mutations or an integrated survival response to cellular stress conserved from unicellular organisms? J Theor Biol 1996;178:375-80.
    • (1996) J Theor Biol , vol.178 , pp. 375-380
    • Israel, L.1
  • 110
    • 84862757952 scopus 로고    scopus 로고
    • Evolutionary dynamics of carcinogenesis and why targeted therapy does not work
    • Gillies RJ, Verduzco D, Gatenby RA. Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. Nat Rev Cancer 2012;12:487-93.
    • (2012) Nat Rev Cancer , vol.12 , pp. 487-493
    • Gillies, R.J.1    Verduzco, D.2    Gatenby, R.A.3
  • 111
    • 84925229458 scopus 로고    scopus 로고
    • Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
    • Eirew P, Steif A, Khattra J, Ha G, Yap D, Farahani H, et al. Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution. Nature 2015;518:422-6.
    • (2015) Nature , vol.518 , pp. 422-426
    • Eirew, P.1    Steif, A.2    Khattra, J.3    Ha, G.4    Yap, D.5    Farahani, H.6
  • 113
    • 80051967505 scopus 로고    scopus 로고
    • Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
    • Gupta PB, Fillmore CM, Jiang G, Shapira SD, Tao K, Kuperwasser C, et al. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell 2011;146:633-44.
    • (2011) Cell , vol.146 , pp. 633-644
    • Gupta, P.B.1    Fillmore, C.M.2    Jiang, G.3    Shapira, S.D.4    Tao, K.5    Kuperwasser, C.6
  • 114
    • 84921629064 scopus 로고    scopus 로고
    • Plasticity within stem cell hierarchies in mammalian epithelia
    • Tetteh PW, Farin HF, Clevers H. Plasticity within stem cell hierarchies in mammalian epithelia. Trends Cell Biol 2015;25:100-8
    • (2015) Trends Cell Biol , vol.25 , pp. 100-108
    • Tetteh, P.W.1    Farin, H.F.2    Clevers, H.3
  • 115
    • 78751676408 scopus 로고    scopus 로고
    • Cells of origin in cancer
    • Visvader JE. Cells of origin in cancer. Nature 2011;469:314-22
    • (2011) Nature , vol.469 , pp. 314-322
    • Visvader, J.E.1
  • 116
    • 35548934558 scopus 로고    scopus 로고
    • MLL translocations, histone modifications and leukaemia stem-cell development
    • Krivtsov AV, Armstrong SA. MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 2007;7:823-33.
    • (2007) Nat Rev Cancer , vol.7 , pp. 823-833
    • Krivtsov, A.V.1    Armstrong, S.A.2
  • 117
    • 34247527730 scopus 로고    scopus 로고
    • Hypoxia-inducible factors, stem cells, and cancer
    • Keith B, Simon MC. Hypoxia-inducible factors, stem cells, and cancer. Cell 2007;129:465-72.
    • (2007) Cell , vol.129 , pp. 465-472
    • Keith, B.1    Simon, M.C.2
  • 118
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009;9:265-73.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 121
    • 79952213086 scopus 로고    scopus 로고
    • Using a stem cell-based signature to guide therapeutic selection in cancer
    • Shats I, Gatza ML, Chang JT, Mori S, Wang J, Rich J, et al. Using a stem cell-based signature to guide therapeutic selection in cancer. Cancer Res 2011;71:1772-80.
    • (2011) Cancer Res , vol.71 , pp. 1772-1780
    • Shats, I.1    Gatza, M.L.2    Chang, J.T.3    Mori, S.4    Wang, J.5    Rich, J.6
  • 122
    • 67649939163 scopus 로고    scopus 로고
    • The increasing complexity of the cancer stem cell paradigm
    • Rosen JM, Jordan CT. The increasing complexity of the cancer stem cell paradigm. Science 2009;324:1670-3.
    • (2009) Science , vol.324 , pp. 1670-1673
    • Rosen, J.M.1    Jordan, C.T.2
  • 123
    • 84858608410 scopus 로고    scopus 로고
    • Cancer stem cells: Impact, heterogeneity, and uncertainty
    • Magee JA, Piskounova E, Morrison SJ. Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell 2012;21:283-96
    • (2012) Cancer Cell , vol.21 , pp. 283-296
    • Magee, J.A.1    Piskounova, E.2    Morrison, S.J.3
  • 124
    • 80052468964 scopus 로고    scopus 로고
    • Stem cell gene expression programs infl uence clinical outcome in human leukemia
    • Eppert K, Takenaka K, Lechman ER, Waldron L, Nilsson B, van Galen P, et al. Stem cell gene expression programs infl uence clinical outcome in human leukemia. Nat Med 2011;17:1086-93.
    • (2011) Nat Med , vol.17 , pp. 1086-1093
    • Eppert, K.1    Takenaka, K.2    Lechman, E.R.3    Waldron, L.4    Nilsson, B.5    Van Galen, P.6
  • 126
    • 73149110562 scopus 로고    scopus 로고
    • Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    • Pece S, Tosoni D, Confalonieri S, Mazzarol G, Vecchi M, Ronzoni S, et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 2010;140:62-73
    • (2010) Cell , vol.140 , pp. 62-73
    • Pece, S.1    Tosoni, D.2    Confalonieri, S.3    Mazzarol, G.4    Vecchi, M.5    Ronzoni, S.6
  • 127
    • 76649128993 scopus 로고    scopus 로고
    • Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype
    • Park SY, Gönen M, Kim HJ, Michor F, Polyak K. Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype. J Clin Invest 2010;120:636-44.
    • (2010) J Clin Invest , vol.120 , pp. 636-644
    • Park, S.Y.1    Gönen, M.2    Kim, H.J.3    Michor, F.4    Polyak, K.5
  • 128
    • 25144433295 scopus 로고    scopus 로고
    • High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival
    • van Rhenen A, Feller N, Kelder A, Westra AH, Rombouts E, Zweegman S, et al. High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival. Clin Cancer Res 2005;11:6520-7.
    • (2005) Clin Cancer Res , vol.11 , pp. 6520-6527
    • Van Rhenen, A.1    Feller, N.2    Kelder, A.3    Westra, A.H.4    Rombouts, E.5    Zweegman, S.6
  • 131
    • 84905856772 scopus 로고    scopus 로고
    • Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival
    • Zhu Z, Khan MA, Weiler M, Blaes J, Jestaedt L, Geibert M, et al. Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival. Cell Stem Cell 2014;15: 185-98.
    • (2014) Cell Stem Cell , vol.15 , pp. 185-198
    • Zhu, Z.1    Khan, M.A.2    Weiler, M.3    Blaes, J.4    Jestaedt, L.5    Geibert, M.6
  • 134
    • 84913565967 scopus 로고    scopus 로고
    • Life cycles, fitness decoupling and the evolution of multicellularity
    • Hammerschmidt K, Rose CJ, Kerr B, Rainey PB. Life cycles, fitness decoupling and the evolution of multicellularity. Nature 2014;515:75-9.
    • (2014) Nature , vol.515 , pp. 75-79
    • Hammerschmidt, K.1    Rose, C.J.2    Kerr, B.3    Rainey, P.B.4
  • 135
    • 77952449083 scopus 로고    scopus 로고
    • Phylostratigraphic tracking of cancer genes suggests a link to the emergence of multicellularity in metazoa
    • Domazet-Loso T, Tautz D. Phylostratigraphic tracking of cancer genes suggests a link to the emergence of multicellularity in metazoa. BMC Biol 2010;8:66.
    • (2010) BMC Biol , vol.8 , pp. 66
    • Domazet-Loso, T.1    Tautz, D.2
  • 136
    • 70349445170 scopus 로고    scopus 로고
    • Abrams JM. P53 ancestry: Gazing through an evolutionary lens
    • Lu WJ, Amatruda JF, Abrams JM. p53 ancestry: gazing through an evolutionary lens. Nat Rev Cancer 2009;9:758-62.
    • (2009) Nat Rev Cancer , vol.9 , pp. 758-762
    • Lu, W.J.1    Amatruda, J.F.2
  • 137
    • 9244224723 scopus 로고    scopus 로고
    • Intrinsic tumour suppression
    • Lowe SW, Cepero E, Evan G. Intrinsic tumour suppression. Nature 2004;432:307-15.
    • (2004) Nature , vol.432 , pp. 307-315
    • Lowe, S.W.1    Cepero, E.2    Evan, G.3
  • 141
    • 79952392467 scopus 로고    scopus 로고
    • Why don’t we get more cancer? A proposed role of the microenvironment in restraining cancer progression
    • Bissell MJ, Hines WC. Why don’t we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nat Med 2011;17:320-9.
    • (2011) Nat Med , vol.17 , pp. 320-329
    • Bissell, M.J.1    Hines, W.C.2
  • 142
    • 79952579323 scopus 로고    scopus 로고
    • Peto’s Paradox: Evolution’s prescription for cancer prevention
    • Caulin AF, Maley CC. Peto’s Paradox: evolution’s prescription for cancer prevention. Trends Ecol Evol 2011;26:175-82.
    • (2011) Trends Ecol Evol , vol.26 , pp. 175-182
    • Caulin, A.F.1    Maley, C.C.2
  • 143
    • 84920808460 scopus 로고    scopus 로고
    • Insights into the evolution of longevity from the bowhead whale genome
    • Keane M, Semeiks J, Webb AE, Li YI, Quesada V, Craig T, et al. Insights into the evolution of longevity from the bowhead whale genome. Cell Rep 2015;10:112-22.
    • (2015) Cell Rep , vol.10 , pp. 112-122
    • Keane, M.1    Semeiks, J.2    Webb, A.E.3    Li, Y.I.4    Quesada, V.5    Craig, T.6
  • 144
    • 84904544431 scopus 로고    scopus 로고
    • Comparative genetics of longevity and cancer: Insights from long-lived rodents
    • Gorbunova V, Seluanov A, Zhang Z, Gladyshev VN, Vijg J. Comparative genetics of longevity and cancer: insights from long-lived rodents. Nat Rev Genet 2014;15:531-40.
    • (2014) Nat Rev Genet , vol.15 , pp. 531-540
    • Gorbunova, V.1    Seluanov, A.2    Zhang, Z.3    Gladyshev, V.N.4    Vijg, J.5
  • 145
    • 0034626769 scopus 로고    scopus 로고
    • The age of cancer
    • DePinho RA. The age of cancer. Nature 2000;408:248-54
    • (2000) Nature , vol.408 , pp. 248-254
    • Depinho, R.A.1
  • 146
    • 77951585057 scopus 로고    scopus 로고
    • Architecture of inherited susceptibility to common cancer
    • Fletcher O, Houlston RS. Architecture of inherited susceptibility to common cancer. Nat Rev Cancer 2010;10:353-61.
    • (2010) Nat Rev Cancer , vol.10 , pp. 353-361
    • Fletcher, O.1    Houlston, R.S.2
  • 148
    • 33847237571 scopus 로고    scopus 로고
    • Darwinian medicine: A case for cancer
    • Greaves M. Darwinian medicine: a case for cancer. Nat Rev Cancer 2007;7:213-21.
    • (2007) Nat Rev Cancer , vol.7 , pp. 213-221
    • Greaves, M.1
  • 150
    • 34249864457 scopus 로고    scopus 로고
    • Longevity among hunter-gatherers: A cross cultural examination
    • Gurven M, Kaplan H. Longevity among hunter-gatherers: a cross cultural examination. Popul Dev Rev 2007;33:321-65.
    • (2007) Popul Dev Rev , vol.33 , pp. 321-365
    • Gurven, M.1    Kaplan, H.2
  • 152
    • 84896894960 scopus 로고    scopus 로고
    • Was skin cancer a selective force for black pigmentation in early hominin evolution?
    • Greaves M. Was skin cancer a selective force for black pigmentation in early hominin evolution? Proc Biol Sci B 2014;281:2013-2955
    • (2014) Proc Biol Sci B , vol.281 , pp. 2013-2955
    • Greaves, M.1
  • 153
    • 77952326915 scopus 로고    scopus 로고
    • Human skin pigmentation as an adaptation to UV radiation
    • Jablonski NG, Chaplin G. Human skin pigmentation as an adaptation to UV radiation. Proc Natl Acad Sci U S A 2010;107(Suppl 2): 8962-8.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 8962-8968
    • Jablonski, N.G.1    Chaplin, G.2
  • 154
    • 84995205128 scopus 로고
    • Are the known chronic diseases related to the human lifespan and its evolution?
    • Weiss KM. Are the known chronic diseases related to the human lifespan and its evolution? Am J Hum Biol 1989;1:307-19
    • (1989) Am J Hum Biol , vol.1 , pp. 307-319
    • Weiss, K.M.1
  • 156
    • 79951938474 scopus 로고    scopus 로고
    • Growth hormone receptor defi ciency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
    • 70ra13
    • Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, Wei M, Madia F, Cheng CW, et al. Growth hormone receptor defi ciency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans. Sci Transl Med 2011;3:70ra13.
    • (2011) Sci Transl Med , vol.3
    • Guevara-Aguirre, J.1    Balasubramanian, P.2    Guevara-Aguirre, M.3    Wei, M.4    Madia, F.5    Cheng, C.W.6
  • 158
    • 33644545382 scopus 로고    scopus 로고
    • Infection, immune responses and the aetiology of childhood leukaemia
    • Greaves M. Infection, immune responses and the aetiology of childhood leukaemia. Nat Rev Cancer 2006;6:193-203.
    • (2006) Nat Rev Cancer , vol.6 , pp. 193-203
    • Greaves, M.1
  • 159
    • 84878261247 scopus 로고    scopus 로고
    • The hen as a model of ovarian cancer
    • Johnson PA, Giles JR. The hen as a model of ovarian cancer. Nat Rev Cancer 2013;13:432-6.
    • (2013) Nat Rev Cancer , vol.13 , pp. 432-436
    • Johnson, P.A.1    Giles, J.R.2
  • 162
    • 84870674626 scopus 로고    scopus 로고
    • Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors
    • Sur IK, Hallikas O, Vaharautio A, Yan J, Turunen M, Enge M, et al. Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors. Science 2012;338:1360-3
    • (2012) Science , vol.338 , pp. 1360-1363
    • Sur, I.K.1    Hallikas, O.2    Vaharautio, A.3    Yan, J.4    Turunen, M.5    Enge, M.6
  • 163
    • 33746255375 scopus 로고    scopus 로고
    • Positive selection in the evolution of cancer
    • Crespi BJ, Summers K. Positive selection in the evolution of cancer. Biol Rev Camb Philos Soc 2006;81:407-24.
    • (2006) Biol Rev Camb Philos Soc , vol.81 , pp. 407-424
    • Crespi, B.J.1    Summers, K.2
  • 164
    • 0036227338 scopus 로고    scopus 로고
    • Cancer causation: The Darwinian downside of past success?
    • Greaves M. Cancer causation: the Darwinian downside of past success? Lancet Oncol 2002;3:244-51.
    • (2002) Lancet Oncol , vol.3 , pp. 244-251
    • Greaves, M.1
  • 166
    • 33748171462 scopus 로고    scopus 로고
    • A scan for signatures of positive selection in candidate loci for skin pigmentation in humans
    • Izagirre N, Garcia I, Junquera C, de la Rua C, Alonso S. A scan for signatures of positive selection in candidate loci for skin pigmentation in humans. Mol Biol Evol 2006;23:1697-706.
    • (2006) Mol Biol Evol , vol.23 , pp. 1697-1706
    • Izagirre, N.1    Garcia, I.2    Junquera, C.3    De La Rua, C.4    Alonso, S.5
  • 167
    • 84885651314 scopus 로고    scopus 로고
    • A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection
    • Zeron-Medina J, Wang X, Repapi E, Campbell MR, Su D, Castro-Giner F, et al. A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection. Cell 2013;155:410-22.
    • (2013) Cell , vol.155 , pp. 410-422
    • Zeron-Medina, J.1    Wang, X.2    Repapi, E.3    Campbell, M.R.4    Su, D.5    Castro-Giner, F.6
  • 168
    • 84858389346 scopus 로고    scopus 로고
    • Outwitting evolution: Fighting drug-resistant TB, malaria, and HIV
    • Goldberg DE, Siliciano RF, Jacobs WR Jr. Outwitting evolution: fighting drug-resistant TB, malaria, and HIV. Cell 2012;148:1271-83
    • (2012) Cell , vol.148 , pp. 1271-1283
    • Goldberg, D.E.1    Siliciano, R.F.2    Jacobs, W.R.3
  • 169
    • 84934966292 scopus 로고    scopus 로고
    • An evolutionary foundation for cancer control
    • Stewart BW, Wild CP, Lyon: International Agency for Research on Cancer (IARC)
    • Greaves M. An evolutionary foundation for cancer control. In: Stewart BW, Wild CP, editors. IARC World Cancer Report 2014. Lyon: International Agency for Research on Cancer (IARC); 2014. p. 337-45.
    • (2014) IARC World Cancer Report 2014 , pp. 337-345
    • Greaves, M.1
  • 170
    • 84921288028 scopus 로고    scopus 로고
    • Variation in cancer risk among tissues can be explained by the number of stem cell divisions
    • Tomasetti C, Vogelstein B. Variation in cancer risk among tissues can be explained by the number of stem cell divisions. Science 2015;347:78-81
    • (2015) Science , vol.347 , pp. 78-81
    • Tomasetti, C.1    Vogelstein, B.2
  • 171
    • 79959981709 scopus 로고    scopus 로고
    • Convergence, adaptation, and constraint
    • Losos JB. Convergence, adaptation, and constraint. Evolution 2011; 65:1827-40.
    • (2011) Evolution , vol.65 , pp. 1827-1840
    • Losos, J.B.1
  • 172
    • 59849107271 scopus 로고    scopus 로고
    • Is genetic evolution predictable?
    • Stern DL, Orgogozo V. Is genetic evolution predictable? Science 2009;323:746-51.
    • (2009) Science , vol.323 , pp. 746-751
    • Stern, D.L.1    Orgogozo, V.2
  • 173
    • 84902775598 scopus 로고    scopus 로고
    • Empirical fitness landscapes and the predict-ability of evolution
    • de Visser JA, Krug J. Empirical fitness landscapes and the predict-ability of evolution. Nat Rev Genet 2014;15:480-90.
    • (2014) Nat Rev Genet , vol.15 , pp. 480-490
    • De Visser, J.A.1    Krug, J.2
  • 174
    • 84875212396 scopus 로고    scopus 로고
    • Understanding, predicting and manipulating the genotypic evolution of antibiotic resistance
    • Palmer AC, Kishony R. Understanding, predicting and manipulating the genotypic evolution of antibiotic resistance. Nat Rev Genet 2013;14:243-8.
    • (2013) Nat Rev Genet , vol.14 , pp. 243-248
    • Palmer, A.C.1    Kishony, R.2
  • 176
    • 84881476503 scopus 로고    scopus 로고
    • High intratumor genetic heterogeneity is related to worse outcome in patients with head and neck squamous cell carcinoma
    • Mroz EA, Tward AD, Pickering CR, Myers JN, Ferris RL, Rocco JW. High intratumor genetic heterogeneity is related to worse outcome in patients with head and neck squamous cell carcinoma. Cancer 2013;119:3034-42.
    • (2013) Cancer , vol.119 , pp. 3034-3042
    • Mroz, E.A.1    Tward, A.D.2    Pickering, C.R.3    Myers, J.N.4    Ferris, R.L.5    Rocco, J.W.6
  • 177
    • 33751217466 scopus 로고    scopus 로고
    • Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment
    • Anderson ARA, Weaver AM, Cummings PT, Quaranta V. Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Cell 2006;127:905-15.
    • (2006) Cell , vol.127 , pp. 905-915
    • Anderson, A.1    Weaver, A.M.2    Cummings, P.T.3    Quaranta, V.4
  • 178
    • 84868034841 scopus 로고    scopus 로고
    • Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling
    • 157ra43
    • Yuan Y, Failmezger H, Rueda OM, Ali HR, Graf S, Chin SF, et al. Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling. Sci Transl Med 2012;4:157ra43
    • (2012) Sci Transl Med , vol.4
    • Yuan, Y.1    Failmezger, H.2    Rueda, O.M.3    Ali, H.R.4    Graf, S.5    Chin, S.F.6
  • 179
    • 84887119057 scopus 로고    scopus 로고
    • Functional heterogeneity of cancer-associated fibroblasts from human colon tumors shows specific prognostic gene expression signature
    • Herrera M, Islam AB, Herrera A, Martin P, Garcia V, Silva J, et al. Functional heterogeneity of cancer-associated fibroblasts from human colon tumors shows specific prognostic gene expression signature. Clin Cancer Res 2013;19:5914-26.
    • (2013) Clin Cancer Res , vol.19 , pp. 5914-5926
    • Herrera, M.1    Islam, A.B.2    Herrera, A.3    Martin, P.4    Garcia, V.5    Silva, J.6
  • 180
    • 84879862659 scopus 로고    scopus 로고
    • Tumor heterogeneity and permeability as measured on the CT component of PET/CT predict survival in patients with non-small cell lung cancer
    • Win T, Miles KA, Janes SM, Ganeshan B, Shastry M, Endozo R, et al. Tumor heterogeneity and permeability as measured on the CT component of PET/CT predict survival in patients with non-small cell lung cancer. Clin Cancer Res 2013;19:3591-9.
    • (2013) Clin Cancer Res , vol.19 , pp. 3591-3599
    • Win, T.1    Miles, K.A.2    Janes, S.M.3    Ganeshan, B.4    Shastry, M.5    Endozo, R.6
  • 181
    • 84863651163 scopus 로고    scopus 로고
    • Combinatorial drug therapy for cancer in the post-genomic era
    • Al-Lazikani B, Banerji U, Workman P. Combinatorial drug therapy for cancer in the post-genomic era. Nat Biotechnol 2012;30:679-92
    • (2012) Nat Biotechnol , vol.30 , pp. 679-692
    • Al-Lazikani, B.1    Banerji, U.2    Workman, P.3
  • 182
    • 84896727479 scopus 로고    scopus 로고
    • Addressing genetic tumor heterogeneity through computationally predictive combination therapy
    • Zhao B, Pritchard JR, Lauffenburger DA, Hemann MT. Addressing genetic tumor heterogeneity through computationally predictive combination therapy. Cancer Discov 2014;4:166-74.
    • (2014) Cancer Discov , vol.4 , pp. 166-174
    • Zhao, B.1    Pritchard, J.R.2    Lauffenburger, D.A.3    Hemann, M.T.4
  • 183
    • 79953283356 scopus 로고    scopus 로고
    • Genetic interactions in cancer progression and treatment
    • Ashworth A, Lord CJ, Reis-Filho JS. Genetic interactions in cancer progression and treatment. Cell 2011;145:30-8.
    • (2011) Cell , vol.145 , pp. 30-38
    • Ashworth, A.1    Lord, C.J.2    Reis-Filho, J.S.3
  • 184
    • 84879440670 scopus 로고    scopus 로고
    • Exploiting ecological principles to better understand cancer progression and treatment
    • 20130020
    • Basanta D, Anderson AR. Exploiting ecological principles to better understand cancer progression and treatment. Interface Focus 2013;3:20130020.
    • (2013) Interface Focus , vol.3
    • Basanta, D.1    Erson, A.R.2
  • 185
    • 84899629319 scopus 로고    scopus 로고
    • Turning ecology and evolution against cancer
    • Korolev KS, Xavier JB, Gore J. Turning ecology and evolution against cancer. Nat Rev Cancer 2014;14:371-80.
    • (2014) Nat Rev Cancer , vol.14 , pp. 371-380
    • Korolev, K.S.1    Xavier, J.B.2    Gore, J.3
  • 186
    • 78650825618 scopus 로고    scopus 로고
    • Effect of daily aspirin on long-term risk of death due to cancer: Analysis of individual patient data from randomised trials
    • Rothwell PM, Fowkes FG, Belch JF, Ogawa H, Warlow CP, Meade TW. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 2011;377:31-41.
    • (2011) Lancet , vol.377 , pp. 31-41
    • Rothwell, P.M.1    Fowkes, F.G.2    Belch, J.F.3    Ogawa, H.4    Warlow, C.P.5    Meade, T.W.6
  • 188
    • 0036090222 scopus 로고    scopus 로고
    • Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to ST1571 in vitro
    • Graham SM, Jørgensen HG, Allan E, Pearson C, Alcorn MJ, Richmond L, et al. Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to ST1571 in vitro. Blood 2002;99:319-25.
    • (2002) Blood , vol.99 , pp. 319-325
    • Graham, S.M.1    Jørgensen, H.G.2    Allan, E.3    Pearson, C.4    Alcorn, M.J.5    Richmond, L.6
  • 191
    • 33645666942 scopus 로고    scopus 로고
    • Darwinian evolution can follow only very few mutational paths to fitter proteins
    • Weinreich DM, Delaney NF, Depristo MA, Hartl DL. Darwinian evolution can follow only very few mutational paths to fitter proteins. Science 2006;312:111-4.
    • (2006) Science , vol.312 , pp. 111-114
    • Weinreich, D.M.1    Delaney, N.F.2    Depristo, M.A.3    Hartl, D.L.4
  • 193
    • 84862776906 scopus 로고    scopus 로고
    • Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
    • Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 2012;481:506-10.
    • (2012) Nature , vol.481 , pp. 506-510
    • Ding, L.1    Ley, T.J.2    Larson, D.E.3    Miller, C.A.4    Koboldt, D.C.5    Welch, J.S.6
  • 195
    • 79951873316 scopus 로고    scopus 로고
    • Cancer tumors as Metazoa 1.0: Tapping genes of ancient ancestors
    • Davies PC, Lineweaver CH. Cancer tumors as Metazoa 1.0: tapping genes of ancient ancestors. Phys Biol 2011;8:015001.
    • (2011) Phys Biol , vol.8
    • Davies, P.C.1    Lineweaver, C.H.2
  • 196
    • 79956305728 scopus 로고    scopus 로고
    • BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition
    • Duy C, Hurtz C, Shojaee S, Cerchietti L, Geng H, Swaminathan S, et al. BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature 2011;473:384-8
    • (2011) Nature , vol.473 , pp. 384-388
    • Duy, C.1    Hurtz, C.2    Shojaee, S.3    Cerchietti, L.4    Geng, H.5    Swaminathan, S.6
  • 197
    • 84859349606 scopus 로고    scopus 로고
    • Exploiting evolution to treat drug resistance: Combination therapy and the double bind
    • Basanta D, Gatenby RA, Anderson AR. Exploiting evolution to treat drug resistance: combination therapy and the double bind. Mol Pharm 2012;9:914-21.
    • (2012) Mol Pharm , vol.9 , pp. 914-921
    • Basanta, D.1    Gatenby, R.A.2    Erson, A.R.3
  • 201
    • 82655179979 scopus 로고    scopus 로고
    • Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties
    • Wang J, Lu F, Ren Q, Sun H, Xu Z, Lan R, et al. Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties. Cancer Res2 011;71:7238-49.
    • Cancer Res2 011 , vol.71 , pp. 7238-7249
    • Wang, J.1    Lu, F.2    Ren, Q.3    Sun, H.4    Xu, Z.5    Lan, R.6


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