Exploiting evolution to treat drug resistance: Combination therapy and the double bind

Molecular Pharmaceutics

Volumn 9, Issue 4, 2012, Pages 914-921

  Basanta, David ^a   Gatenby, Robert A ^a   Anderson, Alexander R A ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

chemotherapy; combination therapy; comensalism; evolutionary double bind; evolutionary game theory; immunotherapy; mathematical modeling

Indexed keywords

CANCER VACCINE; GRANZYME B; PROTEIN P53;

ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER IMMUNOTHERAPY; CANCER RESISTANCE; CELL DIFFERENTIATION; CELL GROWTH; DOWN REGULATION; DRUG RESISTANCE; GAME; HALF LIFE TIME; HUMAN; PHENOTYPE; PRIORITY JOURNAL; PSYCHOLOGICAL THEORY; T LYMPHOCYTE; TUMOR GROWTH;

ANIMALS; DRUG RESISTANCE, NEOPLASM; HUMANS; IMMUNOTHERAPY; MODELS, THEORETICAL; NEOPLASMS;

EID: 84859349606     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200458e     Document Type: Article

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