The butterfly effect in cancer: A single base mutation can remodel the cell

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 4, 2015, Pages 1131-1136

  Hart, Jonathan R ^a   Zhang, Yaoyang ^a   Liao, Lujian ^a   Ueno, Lynn ^a   Du, Lisa ^a   Jonkers, Marloes ^a   Yates, John R ^a   Vogt, Peter K ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Basal breast cancer; Knock in; Molecular signature; RNAseq; SILAC

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; STRUCTURAL PROTEIN; PIK3CA PROTEIN, HUMAN; RNA; TUMOR PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BREAST CANCER; CANCER CELL LINE; DNA REPAIR; ENZYME ACTIVE SITE; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; HISTOLOGY; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR GENE; BREAST TUMOR; ENZYMOLOGY; FEMALE; GENETICS; METABOLISM; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROCEDURES; TUMOR CELL LINE;

AMINO ACID SUBSTITUTION; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA MUTATIONAL ANALYSIS; DNA REPAIR; FEMALE; HUMANS; MUTATION, MISSENSE; NEOPLASM PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; RNA, NEOPLASM;

EID: 84921810171     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1424012112     Document Type: Article

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