-
1
-
-
84859169877
-
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
-
J. Barretina, G. Caponigro, N. Stransky, K. Venkatesan, A.A. Margolin, S. Kim, C.J. Wilson, J. Lehár, G.V. Kryukov, and D. Sonkin The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity Nature 483 2012 603 607
-
(2012)
Nature
, vol.483
, pp. 603-607
-
-
Barretina, J.1
Caponigro, G.2
Stransky, N.3
Venkatesan, K.4
Margolin, A.A.5
Kim, S.6
Wilson, C.J.7
Lehár, J.8
Kryukov, G.V.9
Sonkin, D.10
-
2
-
-
38049150665
-
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
-
J. Bean, C. Brennan, J.-Y. Shih, G. Riely, A. Viale, L. Wang, D. Chitale, N. Motoi, J. Szoke, and S. Broderick MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib Proc. Natl. Acad. Sci. USA 104 2007 20932 20937
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 20932-20937
-
-
Bean, J.1
Brennan, C.2
Shih, J.-Y.3
Riely, G.4
Viale, A.5
Wang, L.6
Chitale, D.7
Motoi, N.8
Szoke, J.9
Broderick, S.10
-
3
-
-
77249119762
-
The landscape of somatic copy-number alteration across human cancers
-
R. Beroukhim, C.H. Mermel, D. Porter, G. Wei, S. Raychaudhuri, J. Donovan, J. Barretina, J.S. Boehm, J. Dobson, and M. Urashima The landscape of somatic copy-number alteration across human cancers Nature 463 2010 899 905
-
(2010)
Nature
, vol.463
, pp. 899-905
-
-
Beroukhim, R.1
Mermel, C.H.2
Porter, D.3
Wei, G.4
Raychaudhuri, S.5
Donovan, J.6
Barretina, J.7
Boehm, J.S.8
Dobson, J.9
Urashima, M.10
-
4
-
-
79952262678
-
Whole-genome comparison reveals novel genetic elements that characterize the genome of industrial strains of Saccharomyces cerevisiae
-
A.R. Borneman, B.A. Desany, D. Riches, J.P. Affourtit, A.H. Forgan, I.S. Pretorius, M. Egholm, and P.J. Chambers Whole-genome comparison reveals novel genetic elements that characterize the genome of industrial strains of Saccharomyces cerevisiae PLoS Genet. 7 2011 e1001287
-
(2011)
PLoS Genet.
, vol.7
, pp. e1001287
-
-
Borneman, A.R.1
Desany, B.A.2
Riches, D.3
Affourtit, J.P.4
Forgan, A.H.5
Pretorius, I.S.6
Egholm, M.7
Chambers, P.J.8
-
5
-
-
47949110827
-
Structural basis for hygromycin B inhibition of protein biosynthesis
-
M.A. Borovinskaya, S. Shoji, K. Fredrick, and J.H.D. Cate Structural basis for hygromycin B inhibition of protein biosynthesis RNA 14 2008 1590 1599
-
(2008)
RNA
, vol.14
, pp. 1590-1599
-
-
Borovinskaya, M.A.1
Shoji, S.2
Fredrick, K.3
Cate, J.H.D.4
-
6
-
-
67651039919
-
A network model of a cooperative genetic landscape in brain tumors
-
M. Bredel, D.M. Scholtens, G.R. Harsh, C. Bredel, J.P. Chandler, J.J. Renfrow, A.K. Yadav, H. Vogel, A.C. Scheck, R. Tibshirani, and B.I. Sikic A network model of a cooperative genetic landscape in brain tumors JAMA 302 2009 261 275
-
(2009)
JAMA
, vol.302
, pp. 261-275
-
-
Bredel, M.1
Scholtens, D.M.2
Harsh, G.R.3
Bredel, C.4
Chandler, J.P.5
Renfrow, J.J.6
Yadav, A.K.7
Vogel, H.8
Scheck, A.C.9
Tibshirani, R.10
Sikic, B.I.11
-
7
-
-
84884365015
-
The causes and consequences of genetic heterogeneity in cancer evolution
-
R.A. Burrell, N. McGranahan, J. Bartek, and C. Swanton The causes and consequences of genetic heterogeneity in cancer evolution Nature 501 2013 338 345
-
(2013)
Nature
, vol.501
, pp. 338-345
-
-
Burrell, R.A.1
McGranahan, N.2
Bartek, J.3
Swanton, C.4
-
8
-
-
78149464968
-
Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae
-
J. St Charles, M.L. Hamilton, and T.D. Petes Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae Genetics 186 2010 537 550
-
(2010)
Genetics
, vol.186
, pp. 537-550
-
-
St Charles, J.1
Hamilton, M.L.2
Petes, T.D.3
-
9
-
-
84862777815
-
Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy
-
G. Chen, W.D. Bradford, C.W. Seidel, and R. Li Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy Nature 482 2012 246 250
-
(2012)
Nature
, vol.482
, pp. 246-250
-
-
Chen, G.1
Bradford, W.D.2
Seidel, C.W.3
Li, R.4
-
10
-
-
84866296846
-
Whole chromosome aneuploidy: Big mutations drive adaptation by phenotypic leap
-
G. Chen, B. Rubinstein, and R. Li Whole chromosome aneuploidy: big mutations drive adaptation by phenotypic leap Bioessays 34 2012 893 900
-
(2012)
Bioessays
, vol.34
, pp. 893-900
-
-
Chen, G.1
Rubinstein, B.2
Li, R.3
-
11
-
-
84887992179
-
Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome
-
T. Davoli, A.W. Xu, K.E. Mengwasser, L.M. Sack, J.C. Yoon, P.J. Park, and S.J. Elledge Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome Cell 155 2013 948 962
-
(2013)
Cell
, vol.155
, pp. 948-962
-
-
Davoli, T.1
Xu, A.W.2
Mengwasser, K.E.3
Sack, L.M.4
Yoon, J.C.5
Park, P.J.6
Elledge, S.J.7
-
12
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
M. Gerlinger, A.J. Rowan, S. Horswell, J. Larkin, D. Endesfelder, E. Gronroos, P. Martinez, N. Matthews, A. Stewart, and P. Tarpey Intratumor heterogeneity and branched evolution revealed by multiregion sequencing N. Engl. J. Med. 366 2012 883 892
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
Martinez, P.7
Matthews, N.8
Stewart, A.9
Tarpey, P.10
-
13
-
-
0142215475
-
Global analysis of protein expression in yeast
-
S. Ghaemmaghami, W.-K. Huh, K. Bower, R.W. Howson, A. Belle, N. Dephoure, E.K. O'Shea, and J.S. Weissman Global analysis of protein expression in yeast Nature 425 2003 737 741
-
(2003)
Nature
, vol.425
, pp. 737-741
-
-
Ghaemmaghami, S.1
Huh, W.-K.2
Bower, K.3
Howson, R.W.4
Belle, A.5
Dephoure, N.6
O'Shea, E.K.7
Weissman, J.S.8
-
14
-
-
84898956673
-
A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole
-
B.D. Harrison, J. Hashemi, M. Bibi, R. Pulver, D. Bavli, Y. Nahmias, M. Wellington, G. Sapiro, and J. Berman A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole PLoS Biol. 12 2014 e1001815
-
(2014)
PLoS Biol.
, vol.12
, pp. e1001815
-
-
Harrison, B.D.1
Hashemi, J.2
Bibi, M.3
Pulver, R.4
Bavli, D.5
Nahmias, Y.6
Wellington, M.7
Sapiro, G.8
Berman, J.9
-
15
-
-
84863115693
-
Subtype and pathway specific responses to anticancer compounds in breast cancer
-
L.M. Heiser, A. Sadanandam, W.-L. Kuo, S.C. Benz, T.C. Goldstein, S. Ng, W.J. Gibb, N.J. Wang, S. Ziyad, and F. Tong Subtype and pathway specific responses to anticancer compounds in breast cancer Proc. Natl. Acad. Sci. USA 109 2012 2724 2729
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 2724-2729
-
-
Heiser, L.M.1
Sadanandam, A.2
Kuo, W.-L.3
Benz, S.C.4
Goldstein, T.C.5
Ng, S.6
Gibb, W.J.7
Wang, N.J.8
Ziyad, S.9
Tong, F.10
-
16
-
-
64349112353
-
A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds
-
C.H. Ho, L. Magtanong, S.L. Barker, D. Gresham, S. Nishimura, P. Natarajan, J.L.Y. Koh, J. Porter, C.A. Gray, and R.J. Andersen A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds Nat. Biotechnol. 27 2009 369 377
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 369-377
-
-
Ho, C.H.1
Magtanong, L.2
Barker, S.L.3
Gresham, D.4
Nishimura, S.5
Natarajan, P.6
Koh, J.L.Y.7
Porter, J.8
Gray, C.A.9
Andersen, R.J.10
-
17
-
-
67649522162
-
Boveri revisited: Chromosomal instability, aneuploidy and tumorigenesis
-
A.J. Holland, and D.W. Cleveland Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis Nat. Rev. Mol. Cell Biol. 10 2009 478 487
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 478-487
-
-
Holland, A.J.1
Cleveland, D.W.2
-
18
-
-
17444446946
-
Widespread aneuploidy revealed by DNA microarray expression profiling
-
T.R. Hughes, C.J. Roberts, H. Dai, A.R. Jones, M.R. Meyer, D. Slade, J. Burchard, S. Dow, T.R. Ward, and M.J. Kidd Widespread aneuploidy revealed by DNA microarray expression profiling Nat. Genet. 25 2000 333 337
-
(2000)
Nat. Genet.
, vol.25
, pp. 333-337
-
-
Hughes, T.R.1
Roberts, C.J.2
Dai, H.3
Jones, A.R.4
Meyer, M.R.5
Slade, D.6
Burchard, J.7
Dow, S.8
Ward, T.R.9
Kidd, M.J.10
-
19
-
-
0347361696
-
Genome-wide amplifications caused by chromosomal rearrangements play a major role in the adaptive evolution of natural yeast
-
J.J. Infante, K.M. Dombek, L. Rebordinos, J.M. Cantoral, and E.T. Young Genome-wide amplifications caused by chromosomal rearrangements play a major role in the adaptive evolution of natural yeast Genetics 165 2003 1745 1759
-
(2003)
Genetics
, vol.165
, pp. 1745-1759
-
-
Infante, J.J.1
Dombek, K.M.2
Rebordinos, L.3
Cantoral, J.M.4
Young, E.T.5
-
20
-
-
78649395022
-
Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia
-
L. Jones, G. Wei, S. Sevcikova, V. Phan, S. Jain, A. Shieh, J.C.Y. Wong, M. Li, J. Dubansky, and M.L. Maunakea Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia J. Exp. Med. 207 2010 2581 2594
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2581-2594
-
-
Jones, L.1
Wei, G.2
Sevcikova, S.3
Phan, V.4
Jain, S.5
Shieh, A.6
Wong, J.C.Y.7
Li, M.8
Dubansky, J.9
Maunakea, M.L.10
-
21
-
-
25444497278
-
The concept of synthetic lethality in the context of anticancer therapy
-
W.G. Kaelin Jr. The concept of synthetic lethality in the context of anticancer therapy Nat. Rev. Cancer 5 2005 689 698
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 689-698
-
-
Kaelin, Jr.W.G.1
-
22
-
-
55449107183
-
Variations in stress sensitivity and genomic expression in diverse S cerevisiae isolates
-
D.J. Kvitek, J.L. Will, and A.P. Gasch Variations in stress sensitivity and genomic expression in diverse S. cerevisiae isolates PLoS Genet. 4 2008 e1000223
-
(2008)
PLoS Genet.
, vol.4
, pp. e1000223
-
-
Kvitek, D.J.1
Will, J.L.2
Gasch, A.P.3
-
23
-
-
79952233635
-
Chromosomal instability confers intrinsic multidrug resistance
-
A.J.X. Lee, D. Endesfelder, A.J. Rowan, A. Walther, N.J. Birkbak, P.A. Futreal, J. Downward, Z. Szallasi, I.P.M. Tomlinson, and M. Howell Chromosomal instability confers intrinsic multidrug resistance Cancer Res. 71 2011 1858 1870
-
(2011)
Cancer Res.
, vol.71
, pp. 1858-1870
-
-
Lee, A.J.X.1
Endesfelder, D.2
Rowan, A.J.3
Walther, A.4
Birkbak, N.J.5
Futreal, P.A.6
Downward, J.7
Szallasi, Z.8
Tomlinson, I.P.M.9
Howell, M.10
-
24
-
-
63249133197
-
Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum
-
P. Leprohon, D. Légaré, F. Raymond, É. Madore, G. Hardiman, J. Corbeil, and M. Ouellette Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum Nucleic Acids Res. 37 2009 1387 1399
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 1387-1399
-
-
Leprohon, P.1
Légaré, D.2
Raymond, F.3
Madore É.4
Hardiman, G.5
Corbeil, J.6
Ouellette, M.7
-
26
-
-
79954842517
-
Extraordinary Trypanosoma cruzi diversity within single mammalian reservoir hosts implies a mechanism of diversifying selection
-
M.S. Llewellyn, J.B. Rivett-Carnac, S. Fitzpatrick, M.D. Lewis, M. Yeo, M.W. Gaunt, and M.A. Miles Extraordinary Trypanosoma cruzi diversity within single mammalian reservoir hosts implies a mechanism of diversifying selection Int. J. Parasitol. 41 2011 609 614
-
(2011)
Int. J. Parasitol.
, vol.41
, pp. 609-614
-
-
Llewellyn, M.S.1
Rivett-Carnac, J.B.2
Fitzpatrick, S.3
Lewis, M.D.4
Yeo, M.5
Gaunt, M.W.6
Miles, M.A.7
-
27
-
-
66149091940
-
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene
-
J. Luo, M.J. Emanuele, D. Li, C.J. Creighton, M.R. Schlabach, T.F. Westbrook, K.-K. Wong, and S.J. Elledge A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene Cell 137 2009 835 848
-
(2009)
Cell
, vol.137
, pp. 835-848
-
-
Luo, J.1
Emanuele, M.J.2
Li, D.3
Creighton, C.J.4
Schlabach, M.R.5
Westbrook, T.F.6
Wong, K.-K.7
Elledge, S.J.8
-
28
-
-
33645396945
-
Genetic clonal diversity predicts progression to esophageal adenocarcinoma
-
C.C. Maley, P.C. Galipeau, J.C. Finley, V.J. Wongsurawat, X. Li, C.A. Sanchez, T.G. Paulson, P.L. Blount, R.-A. Risques, P.S. Rabinovitch, and B.J. Reid Genetic clonal diversity predicts progression to esophageal adenocarcinoma Nat. Genet. 38 2006 468 473
-
(2006)
Nat. Genet.
, vol.38
, pp. 468-473
-
-
Maley, C.C.1
Galipeau, P.C.2
Finley, J.C.3
Wongsurawat, V.J.4
Li, X.5
Sanchez, C.A.6
Paulson, T.G.7
Blount, P.L.8
Risques, R.-A.9
Rabinovitch, P.S.10
Reid, B.J.11
-
30
-
-
0030812876
-
Molecular biological characterization of an azole-resistant Candida glabrata isolate
-
P. Marichal, H. Vanden Bossche, F.C. Odds, G. Nobels, D.W. Warnock, V. Timmerman, C. Van Broeckhoven, S. Fay, and P. Mose-Larsen Molecular biological characterization of an azole-resistant Candida glabrata isolate Antimicrob. Agents Chemother. 41 1997 2229 2237
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 2229-2237
-
-
Marichal, P.1
Vanden Bossche, H.2
Odds, F.C.3
Nobels, G.4
Warnock, D.W.5
Timmerman, V.6
Van Broeckhoven, C.7
Fay, S.8
Mose-Larsen, P.9
-
31
-
-
0030761555
-
Development of fluconazole resistance in Candida albicans causing disseminated infection in a patient undergoing marrow transplantation
-
K.A. Marr, T.C. White, J.-A.H. van Burik, and R.A. Bowden Development of fluconazole resistance in Candida albicans causing disseminated infection in a patient undergoing marrow transplantation Clin. Infect. Dis. 25 1997 908 910
-
(1997)
Clin. Infect. Dis.
, vol.25
, pp. 908-910
-
-
Marr, K.A.1
White, T.C.2
Van Burik, J.-A.H.3
Bowden, R.A.4
-
32
-
-
84861851519
-
Cancer chromosomal instability: Therapeutic and diagnostic challenges
-
N. McGranahan, R.A. Burrell, D. Endesfelder, M.R. Novelli, and C. Swanton Cancer chromosomal instability: therapeutic and diagnostic challenges EMBO Rep. 13 2012 528 538
-
(2012)
EMBO Rep.
, vol.13
, pp. 528-538
-
-
McGranahan, N.1
Burrell, R.A.2
Endesfelder, D.3
Novelli, M.R.4
Swanton, C.5
-
34
-
-
79952345827
-
Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in Trypanosoma cruzi strains revealed by array comparative genomic hybridization
-
T.A. Minning, D.B. Weatherly, S. Flibotte, and R.L. Tarleton Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in Trypanosoma cruzi strains revealed by array comparative genomic hybridization BMC Genomics 12 2011 139
-
(2011)
BMC Genomics
, vol.12
, pp. 139
-
-
Minning, T.A.1
Weatherly, D.B.2
Flibotte, S.3
Tarleton, R.L.4
-
36
-
-
79953766940
-
Tumour evolution inferred by single-cell sequencing
-
N. Navin, J. Kendall, J. Troge, P. Andrews, L. Rodgers, J. McIndoo, K. Cook, A. Stepansky, D. Levy, and D. Esposito Tumour evolution inferred by single-cell sequencing Nature 472 2011 90 94
-
(2011)
Nature
, vol.472
, pp. 90-94
-
-
Navin, N.1
Kendall, J.2
Troge, J.3
Andrews, P.4
Rodgers, L.5
McIndoo, J.6
Cook, K.7
Stepansky, A.8
Levy, D.9
Esposito, D.10
-
37
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network
-
T.C.G.A.R. Network Cancer Genome Atlas Research Network Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature 455 2008 1061 1068
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
Network, T.C.G.A.R.1
-
38
-
-
77952978963
-
Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome
-
A.P. Ng, C.D. Hyland, D. Metcalf, C.L. Carmichael, S.J. Loughran, L. Di Rago, B.T. Kile, and W.S. Alexander Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome Blood 115 2010 3966 3969
-
(2010)
Blood
, vol.115
, pp. 3966-3969
-
-
Ng, A.P.1
Hyland, C.D.2
Metcalf, D.3
Carmichael, C.L.4
Loughran, S.J.5
Di Rago, L.6
Kile, B.T.7
Alexander, W.S.8
-
39
-
-
84884541941
-
Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans
-
M. Ni, M. Feretzaki, W. Li, A. Floyd-Averette, P. Mieczkowski, F.S. Dietrich, and J. Heitman Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans PLoS Biol. 11 2013 e1001653
-
(2013)
PLoS Biol.
, vol.11
, pp. e1001653
-
-
Ni, M.1
Feretzaki, M.2
Li, W.3
Floyd-Averette, A.4
Mieczkowski, P.5
Dietrich, F.S.6
Heitman, J.7
-
40
-
-
70349196502
-
Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay
-
I. Okoli, J.J. Coleman, E. Tempakakis, W.F. An, E. Holson, F. Wagner, A.L. Conery, J. Larkins-Ford, G. Wu, and A. Stern Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay PLoS ONE 4 2009 e7025
-
(2009)
PLoS ONE
, vol.4
, pp. e7025
-
-
Okoli, I.1
Coleman, J.J.2
Tempakakis, E.3
An, W.F.4
Holson, E.5
Wagner, F.6
Conery, A.L.7
Larkins-Ford, J.8
Wu, G.9
Stern, A.10
-
41
-
-
84892420536
-
Aneuploidy: Implications for protein homeostasis and disease
-
A.B. Oromendia, and A. Amon Aneuploidy: implications for protein homeostasis and disease Dis. Model. Mech. 7 2014 15 20
-
(2014)
Dis. Model. Mech.
, vol.7
, pp. 15-20
-
-
Oromendia, A.B.1
Amon, A.2
-
42
-
-
84871596612
-
Aneuploidy causes proteotoxic stress in yeast
-
A.B. Oromendia, S.E. Dodgson, and A. Amon Aneuploidy causes proteotoxic stress in yeast Genes Dev. 26 2012 2696 2708
-
(2012)
Genes Dev.
, vol.26
, pp. 2696-2708
-
-
Oromendia, A.B.1
Dodgson, S.E.2
Amon, A.3
-
43
-
-
78149423336
-
Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
-
N. Pavelka, G. Rancati, J. Zhu, W.D. Bradford, A. Saraf, L. Florens, B.W. Sanderson, G.L. Hattem, and R. Li Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast Nature 468 2010 321 325
-
(2010)
Nature
, vol.468
, pp. 321-325
-
-
Pavelka, N.1
Rancati, G.2
Zhu, J.3
Bradford, W.D.4
Saraf, A.5
Florens, L.6
Sanderson, B.W.7
Hattem, G.L.8
Li, R.9
-
44
-
-
56349088536
-
Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor
-
G. Rancati, N. Pavelka, B. Fleharty, A. Noll, R. Trimble, K. Walton, A. Perera, K. Staehling-Hampton, C.W. Seidel, and R. Li Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor Cell 135 2008 879 893
-
(2008)
Cell
, vol.135
, pp. 879-893
-
-
Rancati, G.1
Pavelka, N.2
Fleharty, B.3
Noll, A.4
Trimble, R.5
Walton, K.6
Perera, A.7
Staehling-Hampton, K.8
Seidel, C.W.9
Li, R.10
-
45
-
-
70449562730
-
Chromosome 7 and 19 trisomy in cultured human neural progenitor cells
-
D. Sareen, E. McMillan, A.D. Ebert, B.C. Shelley, J.A. Johnson, L.F. Meisner, and C.N. Svendsen Chromosome 7 and 19 trisomy in cultured human neural progenitor cells PLoS ONE 4 2009 e7630
-
(2009)
PLoS ONE
, vol.4
, pp. e7630
-
-
Sareen, D.1
McMillan, E.2
Ebert, A.D.3
Shelley, B.C.4
Johnson, J.A.5
Meisner, L.F.6
Svendsen, C.N.7
-
46
-
-
33746506280
-
Aneuploidy and isochromosome formation in drug-resistant Candida albicans
-
A. Selmecki, A. Forche, and J. Berman Aneuploidy and isochromosome formation in drug-resistant Candida albicans Science 313 2006 367 370
-
(2006)
Science
, vol.313
, pp. 367-370
-
-
Selmecki, A.1
Forche, A.2
Berman, J.3
-
47
-
-
41749113291
-
An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1
-
A. Selmecki, M. Gerami-Nejad, C. Paulson, A. Forche, and J. Berman An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1 Mol. Microbiol. 68 2008 624 641
-
(2008)
Mol. Microbiol.
, vol.68
, pp. 624-641
-
-
Selmecki, A.1
Gerami-Nejad, M.2
Paulson, C.3
Forche, A.4
Berman, J.5
-
48
-
-
73449107205
-
Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance
-
A.M. Selmecki, K. Dulmage, L.E. Cowen, J.B. Anderson, and J. Berman Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance PLoS Genet. 5 2009 e1000705
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000705
-
-
Selmecki, A.M.1
Dulmage, K.2
Cowen, L.E.3
Anderson, J.B.4
Berman, J.5
-
49
-
-
0018344962
-
Phenotypic suppression and misreading Saccharomyces cerevisiae
-
A. Singh, D. Ursic, and J. Davies Phenotypic suppression and misreading Saccharomyces cerevisiae Nature 277 1979 146 148
-
(1979)
Nature
, vol.277
, pp. 146-148
-
-
Singh, A.1
Ursic, D.2
Davies, J.3
-
50
-
-
77954047286
-
Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes
-
E. Sionov, H. Lee, Y.C. Chang, and K.J. Kwon-Chung Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes PLoS Pathog. 6 2010 e1000848
-
(2010)
PLoS Pathog.
, vol.6
, pp. e1000848
-
-
Sionov, E.1
Lee, H.2
Chang, Y.C.3
Kwon-Chung, K.J.4
-
52
-
-
33845986330
-
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice
-
R. Sotillo, E. Hernando, E. Díaz-Rodríguez, J. Teruya-Feldstein, C. Cordón-Cardo, S.W. Lowe, and R. Benezra Mad2 overexpression promotes aneuploidy and tumorigenesis in mice Cancer Cell 11 2007 9 23
-
(2007)
Cancer Cell
, vol.11
, pp. 9-23
-
-
Sotillo, R.1
Hernando, E.2
Díaz-Rodríguez, E.3
Teruya-Feldstein, J.4
Cordón-Cardo, C.5
Lowe, S.W.6
Benezra, R.7
-
53
-
-
77949773695
-
Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal
-
R. Sotillo, J.-M. Schvartzman, N.D. Socci, and R. Benezra Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal Nature 464 2010 436 440
-
(2010)
Nature
, vol.464
, pp. 436-440
-
-
Sotillo, R.1
Schvartzman, J.-M.2
Socci, N.D.3
Benezra, R.4
-
54
-
-
84874598318
-
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
-
A. Sottoriva, I. Spiteri, S.G.M. Piccirillo, A. Touloumis, V.P. Collins, J.C. Marioni, C. Curtis, C. Watts, and S. Tavaré Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics Proc. Natl. Acad. Sci. USA 110 2013 4009 4014
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 4009-4014
-
-
Sottoriva, A.1
Spiteri, I.2
Piccirillo, S.G.M.3
Touloumis, A.4
Collins, V.P.5
Marioni, J.C.6
Curtis, C.7
Watts, C.8
Tavaré, S.9
-
55
-
-
79959580788
-
Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole
-
M. Spitzer, E. Griffiths, K.M. Blakely, J. Wildenhain, L. Ejim, L. Rossi, G. De Pascale, J. Curak, E. Brown, M. Tyers, and G.D. Wright Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole Mol. Syst. Biol. 7 2011 499
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 499
-
-
Spitzer, M.1
Griffiths, E.2
Blakely, K.M.3
Wildenhain, J.4
Ejim, L.5
Rossi, L.6
De Pascale, G.7
Curak, J.8
Brown, E.9
Tyers, M.10
Wright, G.D.11
-
56
-
-
77953916528
-
HSP90 at the hub of protein homeostasis: Emerging mechanistic insights
-
M. Taipale, D.F. Jarosz, and S. Lindquist HSP90 at the hub of protein homeostasis: emerging mechanistic insights Nat. Rev. Mol. Cell Biol. 11 2010 515 528
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 515-528
-
-
Taipale, M.1
Jarosz, D.F.2
Lindquist, S.3
-
57
-
-
79951689086
-
Identification of aneuploidy-selective antiproliferation compounds
-
Y.-C. Tang, B.R. Williams, J.J. Siegel, and A. Amon Identification of aneuploidy-selective antiproliferation compounds Cell 144 2011 499 512
-
(2011)
Cell
, vol.144
, pp. 499-512
-
-
Tang, Y.-C.1
Williams, B.R.2
Siegel, J.J.3
Amon, A.4
-
58
-
-
84857130051
-
Targeting EGFR for treatment of glioblastoma: Molecular basis to overcome resistance
-
T.E. Taylor, F.B. Furnari, and W.K. Cavenee Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance Curr. Cancer Drug Targets 12 2012 197 209
-
(2012)
Curr. Cancer Drug Targets
, vol.12
, pp. 197-209
-
-
Taylor, T.E.1
Furnari, F.B.2
Cavenee, W.K.3
-
59
-
-
34548131710
-
Effects of aneuploidy on cellular physiology and cell division in haploid yeast
-
E.M. Torres, T. Sokolsky, C.M. Tucker, L.Y. Chan, M. Boselli, M.J. Dunham, and A. Amon Effects of aneuploidy on cellular physiology and cell division in haploid yeast Science 317 2007 916 924
-
(2007)
Science
, vol.317
, pp. 916-924
-
-
Torres, E.M.1
Sokolsky, T.2
Tucker, C.M.3
Chan, L.Y.4
Boselli, M.5
Dunham, M.J.6
Amon, A.7
-
60
-
-
49049118494
-
Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy
-
J.-M. Ubeda, D. Légaré, F. Raymond, A.A. Ouameur, S. Boisvert, P. Rigault, J. Corbeil, M.J. Tremblay, M. Olivier, B. Papadopoulou, and M. Ouellette Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy Genome Biol. 9 2008 R115
-
(2008)
Genome Biol.
, vol.9
, pp. R115
-
-
Ubeda, J.-M.1
Légaré, D.2
Raymond, F.3
Ouameur, A.A.4
Boisvert, S.5
Rigault, P.6
Corbeil, J.7
Tremblay, M.J.8
Olivier, M.9
Papadopoulou, B.10
Ouellette, M.11
-
61
-
-
84906238686
-
Clonal evolution in breast cancer revealed by single nucleus genome sequencing
-
Y. Wang, J. Waters, M.L. Leung, A. Unruh, W. Roh, X. Shi, K. Chen, P. Scheet, S. Vattathil, and H. Liang Clonal evolution in breast cancer revealed by single nucleus genome sequencing Nature 512 2014 155 160
-
(2014)
Nature
, vol.512
, pp. 155-160
-
-
Wang, Y.1
Waters, J.2
Leung, M.L.3
Unruh, A.4
Roh, W.5
Shi, X.6
Chen, K.7
Scheet, P.8
Vattathil, S.9
Liang, H.10
-
62
-
-
33846065784
-
Aneuploidy acts both oncogenically and as a tumor suppressor
-
B.A.A. Weaver, A.D. Silk, C. Montagna, P. Verdier-Pinard, and D.W. Cleveland Aneuploidy acts both oncogenically and as a tumor suppressor Cancer Cell 11 2007 25 36
-
(2007)
Cancer Cell
, vol.11
, pp. 25-36
-
-
Weaver, B.A.A.1
Silk, A.D.2
Montagna, C.3
Verdier-Pinard, P.4
Cleveland, D.W.5
-
63
-
-
77956268839
-
Understanding resistance to EGFR inhibitors-impact on future treatment strategies. Nature reviews
-
D.L. Wheeler, E.F. Dunn, and P.M. Harari Understanding resistance to EGFR inhibitors-impact on future treatment strategies. Nature reviews Clin. Oncol. 7 2010 493 507
-
(2010)
Clin. Oncol.
, vol.7
, pp. 493-507
-
-
Wheeler, D.L.1
Dunn, E.F.2
Harari, P.M.3
-
64
-
-
84863691442
-
Karyotypic determinants of chromosome instability in aneuploid budding yeast
-
J. Zhu, N. Pavelka, W.D. Bradford, G. Rancati, and R. Li Karyotypic determinants of chromosome instability in aneuploid budding yeast PLoS Genet. 8 2012 e1002719
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002719
-
-
Zhu, J.1
Pavelka, N.2
Bradford, W.D.3
Rancati, G.4
Li, R.5
|