메뉴 건너뛰기




Volumn 481, Issue 7381, 2012, Pages 306-313

Clonal evolution in cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARCINOGEN;

EID: 84856013431     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10762     Document Type: Review
Times cited : (2317)

References (100)
  • 1
    • 41349099104 scopus 로고    scopus 로고
    • Cancer statistics 2008
    • Jemal, A. et al. Cancer statistics, 2008. CA Cancer J. Clin. 58, 71-96 (2008).
    • (2008) CA Cancer J. Clin. , vol.58 , pp. 71-96
    • Jemal, A.1
  • 2
    • 79953158399 scopus 로고    scopus 로고
    • Exploring the genomes of cancer cells: Progress and promise
    • Stratton, M. R. Exploring the genomes of cancer cells: progress and promise. Science 331, 1553-1558 (2011).
    • (2011) Science , vol.331 , pp. 1553-1558
    • Stratton, M.R.1
  • 3
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell, P. C. The clonal evolution of tumor cell populations. Science 194, 23-28 (1976).
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 4
    • 33845243362 scopus 로고    scopus 로고
    • Cancer as an evolutionary and ecological process
    • DOI 10.1038/nrc2013, PII NRC2013
    • Merlo, L. M., Pepper, J. W., Reid, B. J. & Maley, C. C. Cancer as an evolutionary and ecological process. Nature Rev. Cancer 6, 924-935 (2006). (Pubitemid 44862677)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.12 , pp. 924-935
    • Merlo, L.M.F.1    Pepper, J.W.2    Reid, B.J.3    Maley, C.C.4
  • 7
    • 0027244510 scopus 로고
    • The frequency of carcinoma and intraepithelial neoplasia of the prostate in young male patients
    • Sakr, W. A., Haas, G. P., Cassin, B. F., Pontes, J. E. & Crissman, J. D. The frequency of carcinoma and intraepithelial neoplasia of the prostate in young male patients. J. Urol. 150, 379-385 (1993). (Pubitemid 23215874)
    • (1993) Journal of Urology , vol.150 , Issue.2 , pp. 379-385
    • Sakr, W.A.1    Haas, G.P.2    Cassin, B.F.3    Pontes, J.E.4    Crissman, J.D.5
  • 9
    • 75149134769 scopus 로고    scopus 로고
    • Barrett's oesophagus and oesophageal adenocarcinoma: Time for a new synthesis
    • Reid, B. J., Li, X., Galipeau, P. C. & Vaughan, T. L. Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis. Nature Rev. Cancer 10, 87-101 (2010).
    • (2010) Nature Rev. Cancer , vol.10 , pp. 87-101
    • Reid, B.J.1    Li, X.2    Galipeau, P.C.3    Vaughan, T.L.4
  • 10
    • 63049102497 scopus 로고    scopus 로고
    • Parallel progression of primary tumours and metastases
    • Klein, C. A. Parallel progression of primary tumours and metastases. Nature Rev. Cancer 9, 302-312 (2009).
    • (2009) Nature Rev. Cancer , vol.9 , pp. 302-312
    • Klein, C.A.1
  • 11
    • 0015854554 scopus 로고
    • The relationship between growth rate, labelling index and histological type of human solid tumours
    • Malaise, E. P., Chavaudra, N. & Tubiana, M. The relationship between growth rate, labelling index and histological type of human solid tumours. Eur. J. Cancer 9, 305-312 (1973).
    • (1973) Eur. J. Cancer , vol.9 , pp. 305-312
    • Malaise, E.P.1    Chavaudra, N.2    Tubiana, M.3
  • 12
    • 57349185631 scopus 로고    scopus 로고
    • Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity
    • Tsai, A. G. et al. Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. Cell 135, 1130-1142 (2008).
    • (2008) Cell , vol.135 , pp. 1130-1142
    • Tsai, A.G.1
  • 15
    • 28544438548 scopus 로고    scopus 로고
    • Radiation and the microenvironment-tumorigenesis and therapy
    • Barcellos-Hoff, M. H., Park, C. & Wright, E. G. Radiation and the microenvironment-tumorigenesis and therapy. Nature Rev. Cancer 5, 867-875 (2005).
    • (2005) Nature Rev. Cancer , vol.5 , pp. 867-875
    • Barcellos-Hoff, M.H.1    Park, C.2    Wright, E.G.3
  • 16
    • 2442649306 scopus 로고    scopus 로고
    • Selectively advantageous mutations and hitchhikers in neoplasms: P16 lesions are selected in Barrett's esophagus
    • DOI 10.1158/0008-5472.CAN-03-3249
    • Maley, C. C. et al. Selectively advantageous mutations and hitchhikers in neoplasms: p16 lesions are selected in Barrett's esophagus. Cancer Res. 64, 3414-3427 (2004). (Pubitemid 38657913)
    • (2004) Cancer Research , vol.64 , Issue.10 , pp. 3414-3427
    • Maley, C.C.1    Galipeau, P.C.2    Li, X.3    Sanchez, C.A.4    Paulson, T.G.5    Reid, B.J.6
  • 17
    • 84983720414 scopus 로고    scopus 로고
    • Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data
    • Tao, Y. et al. Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc. Natl Acad. Sci. USA 108, 12042-12047 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 12042-12047
    • Tao, Y.1
  • 18
    • 77249123407 scopus 로고    scopus 로고
    • Signatures of mutation and selection in the cancer genome
    • Bignell, G. R. et al. Signatures of mutation and selection in the cancer genome. Nature 463, 893-898 (2010).
    • (2010) Nature , vol.463 , pp. 893-898
    • Bignell, G.R.1
  • 19
    • 78651439545 scopus 로고    scopus 로고
    • Identifying cancer driver genes in tumor genome sequencing studies
    • Youn, A. & Simon, R. Identifying cancer driver genes in tumor genome sequencing studies. Bioinformatics 27, 175-181 (2011).
    • (2011) Bioinformatics , vol.27 , pp. 175-181
    • Youn, A.1    Simon, R.2
  • 20
    • 33747869580 scopus 로고    scopus 로고
    • Statistical analysis of pathogenicity of somatic mutations in cancer
    • DOI 10.1534/genetics.105.044677
    • Greenman, C., Wooster, R., Futreal, P. A., Stratton, M. R. & Easton, D. F. Statistical analysis of pathogenicity of somatic mutations in cancer. Genetics 173, 2187-2198 (2006). (Pubitemid 44285695)
    • (2006) Genetics , vol.173 , Issue.4 , pp. 2187-2198
    • Greenman, C.1    Wooster, R.2    Futreal, P.A.3    Stratton, M.R.4    Easton, D.F.5
  • 21
    • 78249261016 scopus 로고    scopus 로고
    • Accumulation of driver and passenger mutations during tumor progression
    • Bozic, I. et al. Accumulation of driver and passenger mutations during tumor progression. Proc. Natl Acad. Sci. USA 107, 18545-18550 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 18545-18550
    • Bozic, I.1
  • 22
    • 30344444783 scopus 로고    scopus 로고
    • The molecular basis of common and rare fragile sites
    • DOI 10.1016/j.canlet.2005.07.039, PII S0304383505008268
    • Schwartz, M., Zlotorynski, E. & Kerem, B. The molecular basis of common and rare fragile sites. Cancer Lett. 232, 13-26 (2006). (Pubitemid 43054977)
    • (2006) Cancer Letters , vol.232 , Issue.1 , pp. 13-26
    • Schwartz, M.1    Zlotorynski, E.2    Kerem, B.3
  • 23
    • 79957501125 scopus 로고    scopus 로고
    • Human cancers express mutator phenotypes: Origin, consequences and targeting
    • Loeb, L. A. Human cancers express mutator phenotypes: origin, consequences and targeting. Nature Rev. Cancer 11, 450-457 (2011).
    • (2011) Nature Rev. Cancer , vol.11 , pp. 450-457
    • Loeb, L.A.1
  • 25
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 26
    • 63849149890 scopus 로고    scopus 로고
    • Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers
    • Siegmund, K. D., Marjoram, P., Woo, Y. J., Tavare, S. & Shibata, D. Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers. Proc. Natl Acad. Sci. USA 106, 4828-4833 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 4828-4833
    • Siegmund, K.D.1    Marjoram, P.2    Woo, Y.J.3    Tavare, S.4    Shibata, D.5
  • 27
    • 69049103181 scopus 로고    scopus 로고
    • Intra-tumor heterogeneity of MLH1 promoter methylation revealed by deep single molecule bisulfite sequencing
    • Varley, K. E., Mutch, D. G., Edmonston, T. B., Goodfellow, P. J. & Mitra, R. D. Intra-tumor heterogeneity of MLH1 promoter methylation revealed by deep single molecule bisulfite sequencing. Nucleic Acids Res. 37, 4603-4612 (2009).
    • (2009) Nucleic Acids Res. , vol.37 , pp. 4603-4612
    • Varley, K.E.1    Mutch, D.G.2    Edmonston, T.B.3    Goodfellow, P.J.4    Mitra, R.D.5
  • 28
    • 84859247862 scopus 로고    scopus 로고
    • Overlooking evolution: A systematic analysis of cancer relapse and therapeutic resistance research
    • Aktipis, C. A., Kwan, V. S. Y., Johnson, K. A., Neuberg, S. L. & Maley, C. C. Overlooking evolution: a systematic analysis of cancer relapse and therapeutic resistance research. PLoS ONE 6, e261000 (2011).
    • (2011) PLoS ONE , vol.6
    • Aktipis, C.A.1    Kwan, V.S.Y.2    Johnson, K.A.3    Neuberg, S.L.4    Maley, C.C.5
  • 29
    • 36949025507 scopus 로고    scopus 로고
    • Genetic progression and the waiting time to cancer
    • Beerenwinkel, N. et al. Genetic progression and the waiting time to cancer. PLoS Comput. Biol. 3, e225 (2007).
    • (2007) PLoS Comput. Biol. , vol.3
    • Beerenwinkel, N.1
  • 30
    • 33646204788 scopus 로고    scopus 로고
    • Clonal interference and the periodic selection of new beneficial mutations in Escherichia coli
    • de Visser, J. A. & Rozen, D. E. Clonal interference and the periodic selection of new beneficial mutations in Escherichia coli. Genetics 172, 2093-2100 (2006).
    • (2006) Genetics , vol.172 , pp. 2093-2100
    • De Visser, J.A.1    Rozen, D.E.2
  • 31
    • 48249128273 scopus 로고    scopus 로고
    • Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus
    • Leedham, S. J. et al. Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus. Gut 57, 1041-1048 (2008).
    • (2008) Gut , vol.57 , pp. 1041-1048
    • Leedham, S.J.1
  • 32
    • 79953766940 scopus 로고    scopus 로고
    • Tumour evolution inferred by single-cell sequencing
    • Navin, N. et al. Tumour evolution inferred by single-cell sequencing. Nature 472, 90-94 (2011).
    • (2011) Nature , vol.472 , pp. 90-94
    • Navin, N.1
  • 33
    • 78751644099 scopus 로고    scopus 로고
    • Genetic variegation of clonal architecture and propagating cells in leukaemia
    • Anderson, K. et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 469, 356-361 (2011).
    • (2011) Nature , vol.469 , pp. 356-361
    • Anderson, K.1
  • 34
    • 0032983538 scopus 로고    scopus 로고
    • Colorectal adenoma and cancer divergence. Evidence of multilineage progression
    • Tsao, J. L. et al. Colorectal adenoma and cancer divergence. Evidence of multilineage progression. Am. J. Pathol. 154, 1815-1824 (1999).
    • (1999) Am. J. Pathol. , vol.154 , pp. 1815-1824
    • Tsao, J.L.1
  • 35
    • 33645396945 scopus 로고    scopus 로고
    • Genetic clonal diversity predicts progression to esophageal adenocarcinoma
    • Maley, C. C. et al. Genetic clonal diversity predicts progression to esophageal adenocarcinoma. Nature Genet. 38, 468-473 (2006).
    • (2006) Nature Genet. , vol.38 , pp. 468-473
    • Maley, C.C.1
  • 36
    • 0026569818 scopus 로고
    • Clonal expansion of p53 mutant cells is associated with brain tumour progression
    • Sidransky, D. et al. Clonal expansion of p53 mutant cells is associated with brain tumour progression. Nature 355, 846-847 (1992).
    • (1992) Nature , vol.355 , pp. 846-847
    • Sidransky, D.1
  • 37
    • 78049398107 scopus 로고    scopus 로고
    • Distant metastasis occurs late during the genetic evolution of pancreatic cancer
    • Yachida, S. et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 467, 1114-1117 (2010).
    • (2010) Nature , vol.467 , pp. 1114-1117
    • Yachida, S.1
  • 38
    • 0027790582 scopus 로고
    • Punctuated equilibrium comes of age
    • DOI 10.1038/366223a0
    • Gould, S. J. & Eldredge, N. Punctuated equilibrium comes of age. Nature 366, 223-227 (1993). (Pubitemid 24410249)
    • (1993) Nature , vol.366 , Issue.6452 , pp. 223-227
    • Gould, S.J.1    Eldredge, N.2
  • 39
    • 78650959663 scopus 로고    scopus 로고
    • Massive genomic rearrangement acquired in a single catastrophic event during cancer development
    • Stephens, P. J. et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144, 27-40 (2011).
    • (2011) Cell , vol.144 , pp. 27-40
    • Stephens, P.J.1
  • 40
    • 51349126920 scopus 로고    scopus 로고
    • Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing
    • Campbell, P. J. et al. Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing. Proc. Natl Acad. Sci. USA 105, 13081-13086 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 13081-13086
    • Campbell, P.J.1
  • 41
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • DOI 10.1038/nrc2256, PII NRC2256
    • Aguirre-Ghiso, J. A. Models, mechanisms and clinical evidence for cancer dormancy. Nature Rev. Cancer 7, 834-846 (2007). (Pubitemid 350006258)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.11 , pp. 834-846
    • Aguirre-Ghiso, J.A.1
  • 42
    • 70449552851 scopus 로고    scopus 로고
    • Immunologically silent cancer clone transmission from mother to offspring
    • Isoda, T. et al. Immunologically silent cancer clone transmission from mother to offspring. Proc. Natl Acad. Sci. USA 106, 17882-17885 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 17882-17885
    • Isoda, T.1
  • 43
    • 79952593287 scopus 로고    scopus 로고
    • Contagious cancer
    • Welsh, J. S. Contagious cancer. Oncologist 16, 1-4 (2011).
    • (2011) Oncologist , vol.16 , pp. 1-4
    • Welsh, J.S.1
  • 44
    • 37549013776 scopus 로고    scopus 로고
    • A microenvironmental model of carcinogenesis
    • Gatenby, R. A. & Gillies, R. J. A microenvironmental model of carcinogenesis. Nature Rev. Cancer 8, 56-61 (2008).
    • (2008) Nature Rev. Cancer , vol.8 , pp. 56-61
    • Gatenby, R.A.1    Gillies, R.J.2
  • 45
    • 33745515023 scopus 로고    scopus 로고
    • Tumour microenvironment - TGF: The molecular Jekyll and Hyde of cancer
    • DOI 10.1038/nrc1926, PII N1926
    • Bierie, B. & Moses, H. L. Tumour microenvironment: TGFb: the molecular Jekyll and Hyde of cancer. Nature Rev. Cancer 6, 506-520 (2006). (Pubitemid 43980540)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.7 , pp. 506-520
    • Bierie, B.1    Moses, H.L.2
  • 46
    • 79955702339 scopus 로고    scopus 로고
    • Deadly teamwork: Neural cancer stem cells and the tumor microenvironment
    • Lathia, J. D., Heddleston, J. M., Venere, M. & Rich, J. N. Deadly teamwork: neural cancer stem cells and the tumor microenvironment. Cell Stem Cell 8, 482-485 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 482-485
    • Lathia, J.D.1    Heddleston, J.M.2    Venere, M.3    Rich, J.N.4
  • 47
    • 0016692602 scopus 로고
    • Mutation selection and the natural history of cancer
    • Cairns, J. Mutation selection and the natural history of cancer. Nature 255, 197-200 (1975).
    • (1975) Nature , vol.255 , pp. 197-200
    • Cairns, J.1
  • 48
    • 33751217466 scopus 로고    scopus 로고
    • Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment
    • DOI 10.1016/j.cell.2006.09.042, PII S0092867406013481
    • Anderson, A. R., Weaver, A. M., Cummings, P. T. & Quaranta, V. Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Cell 127, 905-915 (2006). (Pubitemid 44792251)
    • (2006) Cell , vol.127 , Issue.5 , pp. 905-915
    • Anderson, A.R.A.1    Weaver, A.M.2    Cummings, P.T.3    Quaranta, V.4
  • 49
    • 79955700272 scopus 로고    scopus 로고
    • Solving the puzzle of metastasis: The evolution of cell migration in neoplasms
    • Chen, J., Sprouffske, K., Huang, Q. & Maley, C. C. Solving the puzzle of metastasis: the evolution of cell migration in neoplasms. PLoS ONE 6, e17933 (2011).
    • (2011) PLoS ONE , vol.6
    • Chen, J.1    Sprouffske, K.2    Huang, Q.3    Maley, C.C.4
  • 50
    • 59649117924 scopus 로고    scopus 로고
    • Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization
    • Mazzone, M. et al. Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization. Cell 136, 839-851 (2009).
    • (2009) Cell , vol.136 , pp. 839-851
    • Mazzone, M.1
  • 51
    • 77958501473 scopus 로고    scopus 로고
    • DNA damage-mediated induction of a chemoresistant niche
    • Gilbert, L. A. & Hemann, M. T. DNA damage-mediated induction of a chemoresistant niche. Cell 143, 355-366 (2010).
    • (2010) Cell , vol.143 , pp. 355-366
    • Gilbert, L.A.1    Hemann, M.T.2
  • 53
    • 77951139631 scopus 로고    scopus 로고
    • Genome remodelling in a basal-like breast cancer metastasis and xenograft
    • Ding, L. et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 464, 999-1005 (2010).
    • (2010) Nature , vol.464 , pp. 999-1005
    • Ding, L.1
  • 54
    • 79960093087 scopus 로고    scopus 로고
    • Accurate reconstruction of the temporal order of mutations in neoplastic progression
    • Sprouffske, K., Pepper, J. W. & Maley, C. C. Accurate reconstruction of the temporal order of mutations in neoplastic progression. Cancer Prev. Res. 4, 1135-1144 (2011).
    • (2011) Cancer Prev. Res. , vol.4 , pp. 1135-1144
    • Sprouffske, K.1    Pepper, J.W.2    Maley, C.C.3
  • 55
    • 0141482011 scopus 로고    scopus 로고
    • Leukemia in twins: Lessons in natural history
    • DOI 10.1182/blood-2002-12-3817
    • Greaves, M. F., Maia, A. T., Wiemels, J. L. & Ford, A. M. Leukemia in twins: lessons in natural history. Blood 102, 2321-2333 (2003). (Pubitemid 37193565)
    • (2003) Blood , vol.102 , Issue.7 , pp. 2321-2333
    • Greaves, M.F.1    Maia, A.T.2    Wiemels, J.L.3    Ford, A.M.4
  • 56
    • 77951751194 scopus 로고    scopus 로고
    • Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia
    • Bateman, C. M. et al. Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia. Blood 115, 3553-3558 (2010).
    • (2010) Blood , vol.115 , pp. 3553-3558
    • Bateman, C.M.1
  • 57
    • 14644396631 scopus 로고    scopus 로고
    • Testicular germ-cell tumours in a broader perspective
    • DOI 10.1038/nrc1568
    • Oosterhuis, J. W. & Looijenga, L. H. Testicular germ-cell tumours in a broader perspective. Nature Rev. Cancer 5, 210-222 (2005). (Pubitemid 40314952)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.3 , pp. 210-222
    • Oosterhuis, J.W.1    Looijenga, L.H.J.2
  • 59
    • 80055101101 scopus 로고    scopus 로고
    • Temporal dissection of tumorigenesis in primary cancers
    • Durinck, S. et al. Temporal dissection of tumorigenesis in primary cancers. Cancer Discov. 1, 137-143 (2011).
    • (2011) Cancer Discov. , vol.1 , pp. 137-143
    • Durinck, S.1
  • 60
    • 0036792092 scopus 로고    scopus 로고
    • Metapopulation dynamics and spatial heterogeneity in cancer
    • Gonzalez-Garcia, I., Sole, R. V. & Costa, J. Metapopulation dynamics and spatial heterogeneity in cancer. Proc. Natl Acad. Sci. USA 99, 13085-13089 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 13085-13089
    • Gonzalez-Garcia, I.1    Sole, R.V.2    Costa, J.3
  • 62
    • 74949101897 scopus 로고    scopus 로고
    • Inferring tumor progression from genomic heterogeneity
    • Navin, N. et al. Inferring tumor progression from genomic heterogeneity. Genome Res. 20, 68-80 (2010).
    • (2010) Genome Res. , vol.20 , pp. 68-80
    • Navin, N.1
  • 64
    • 76649128993 scopus 로고    scopus 로고
    • Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype
    • Park, S. Y., Gonen, M., Kim, H. J., Michor, F. & Polyak, K. Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype. J. Clin. Invest. 120, 636-644 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 636-644
    • Park, S.Y.1    Gonen, M.2    Kim, H.J.3    Michor, F.4    Polyak, K.5
  • 65
    • 78649248733 scopus 로고    scopus 로고
    • A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma
    • Merlo, L. M. et al. A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma. Cancer Prev. Res. 3, 1388-1397 (2010).
    • (2010) Cancer Prev. Res. , vol.3 , pp. 1388-1397
    • Merlo, L.M.1
  • 66
    • 58149380742 scopus 로고    scopus 로고
    • Stem cell concepts renew cancer research
    • Dick, J. E. Stem cell concepts renew cancer research. Blood 112, 4793-4807 (2008).
    • (2008) Blood , vol.112 , pp. 4793-4807
    • Dick, J.E.1
  • 67
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • DOI 10.1038/35102167
    • Reya, T., Morrison, S. J., Clarke, M. F. & Weissman, I. L. Stem cells, cancer, and cancer stem cells. Nature 414, 105-111 (2001). (Pubitemid 33041634)
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 68
    • 80052503103 scopus 로고    scopus 로고
    • Cancer stem cells renew their impact
    • Greaves, M. Cancer stem cells renew their impact. Nature Med. 17, 1046-1048 (2011).
    • (2011) Nature Med. , vol.17 , pp. 1046-1048
    • Greaves, M.1
  • 69
    • 67649939163 scopus 로고    scopus 로고
    • The increasing complexity of the cancer stem cell paradigm
    • Rosen, J. M. & Jordan, C. T. The increasing complexity of the cancer stem cell paradigm. Science 324, 1670-1673 (2009).
    • (2009) Science , vol.324 , pp. 1670-1673
    • Rosen, J.M.1    Jordan, C.T.2
  • 70
    • 77953811725 scopus 로고    scopus 로고
    • Cancer stem cells: Back to Darwin? Semin
    • Greaves, M. Cancer stem cells: back to Darwin? Semin. Cancer Biol. 20, 65-70 (2010).
    • (2010) Cancer Biol. , vol.20 , pp. 65-70
    • Greaves, M.1
  • 71
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • Gupta, P. B. et al. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138, 645-659 (2009).
    • (2009) Cell , vol.138 , pp. 645-659
    • Gupta, P.B.1
  • 73
    • 43449084346 scopus 로고    scopus 로고
    • Arf-/- multipotent progenitors
    • DOI 10.1038/nature06869, PII NATURE06869
    • Akala, O. O. et al. Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/-multipotent progenitors. Nature 453, 228-232 (2008). (Pubitemid 351667977)
    • (2008) Nature , vol.453 , Issue.7192 , pp. 228-232
    • Akala, O.O.1    Park, I.-K.2    Qian, D.3    Pihalja, M.4    Becker, M.W.5    Clarke, M.F.6
  • 75
    • 79851510907 scopus 로고    scopus 로고
    • Somatic mutations in cancer prognosis and prediction: Lessons from TP53 and EGFR genes
    • Olivier, M. & Taniere, P. Somatic mutations in cancer prognosis and prediction: lessons from TP53 and EGFR genes. Curr. Opin. Oncol. 23, 88-92 (2011).
    • (2011) Curr. Opin. Oncol. , vol.23 , pp. 88-92
    • Olivier, M.1    Taniere, P.2
  • 76
    • 78651100119 scopus 로고    scopus 로고
    • Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures
    • Mizuno, H., Spike, B. T., Wahl, G. M. & Levine, A. J. Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures. Proc. Natl Acad. Sci. USA 107, 22745-22750 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 22745-22750
    • Mizuno, H.1    Spike, B.T.2    Wahl, G.M.3    Levine, A.J.4
  • 77
    • 70349123829 scopus 로고    scopus 로고
    • The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells
    • Cicalese, A. et al. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. Cell 138, 1083-1095 (2009).
    • (2009) Cell , vol.138 , pp. 1083-1095
    • Cicalese, A.1
  • 78
    • 57349143739 scopus 로고    scopus 로고
    • Efficient tumour formation by single human melanoma cells
    • Quintana, E. et al. Efficient tumour formation by single human melanoma cells. Nature 456, 593-598 (2008).
    • (2008) Nature , vol.456 , pp. 593-598
    • Quintana, E.1
  • 79
    • 73149110562 scopus 로고    scopus 로고
    • Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    • Pece, S. et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 140, 62-73 (2010).
    • (2010) Cell , vol.140 , pp. 62-73
    • Pece, S.1
  • 80
    • 78751661556 scopus 로고    scopus 로고
    • Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells
    • Notta, F. et al. Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. Nature 469, 362-367 (2011).
    • (2011) Nature , vol.469 , pp. 362-367
    • Notta, F.1
  • 81
    • 79955711142 scopus 로고    scopus 로고
    • Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse
    • Clappier, E. et al. Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse. J. Exp. Med. 208, 653-661 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 653-661
    • Clappier, E.1
  • 82
    • 74949090309 scopus 로고    scopus 로고
    • The therapeutic promise of the cancer stem cell concept
    • Frank, N. Y., Schatton, T. & Frank, M. H. The therapeutic promise of the cancer stem cell concept. J. Clin. Invest. 120, 41-50 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 41-50
    • Frank, N.Y.1    Schatton, T.2    Frank, M.H.3
  • 84
    • 75549083303 scopus 로고    scopus 로고
    • Tumor heterogeneity: Causes and consequences
    • Marusyk, A. & Polyak, K. Tumor heterogeneity: causes and consequences. Biochim. Biophys. Acta 1805, 105-117 (2010).
    • (2010) Biochim. Biophys. Acta , pp. 105-117
    • Marusyk, A.1    Polyak, K.2
  • 85
    • 65049084510 scopus 로고    scopus 로고
    • Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution
    • Piccirillo, S. G. M. et al. Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution. Oncogene 28, 1807-1811 (2009).
    • (2009) Oncogene , vol.28 , pp. 1807-1811
    • Piccirillo, S.G.M.1
  • 86
    • 78650373172 scopus 로고    scopus 로고
    • How melanomas bypass new therapy
    • Solit, D. & Sawyers, C. L. How melanomas bypass new therapy. Nature 468, 902-903 (2010).
    • (2010) Nature , vol.468 , pp. 902-903
    • Solit, D.1    Sawyers, C.L.2
  • 87
    • 77949884311 scopus 로고    scopus 로고
    • Cycling toward elimination of leukemic stem cells
    • Goff, D. & Jamieson, C. Cycling toward elimination of leukemic stem cells. Cell Stem Cell 6, 296-297 (2010).
    • (2010) Cell Stem Cell , vol.6 , pp. 296-297
    • Goff, D.1    Jamieson, C.2
  • 88
    • 77950809059 scopus 로고    scopus 로고
    • A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
    • Sharma, S. V. et al. A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell 141, 69-80 (2010).
    • (2010) Cell , vol.141 , pp. 69-80
    • Sharma, S.V.1
  • 89
    • 79952395270 scopus 로고    scopus 로고
    • Cancer genomics: From discovery science to personalized medicine
    • Chin, L., Andersen, J. N. & Futreal, P. A. Cancer genomics: from discovery science to personalized medicine. Nature Med. 17, 297-303 (2011).
    • (2011) Nature Med. , vol.17 , pp. 297-303
    • Chin, L.1    Andersen, J.N.2    Futreal, P.A.3
  • 90
    • 70350435633 scopus 로고    scopus 로고
    • Shifting paradigms: The seeds of oncogene addiction
    • Sawyers, C. L. Shifting paradigms: the seeds of oncogene addiction. Nature Med. 15, 1158-1161 (2009).
    • (2009) Nature Med. , vol.15 , pp. 1158-1161
    • Sawyers, C.L.1
  • 91
    • 0036090222 scopus 로고    scopus 로고
    • Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro
    • Graham, S. M. et al. Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro. Blood 99, 319-325 (2002).
    • (2002) Blood , vol.99 , pp. 319-325
    • Graham, S.M.1
  • 92
    • 73649102105 scopus 로고    scopus 로고
    • Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC
    • Turke, A. B. et al. Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC. Cancer Cell 17, 77-88 (2010).
    • (2010) Cancer Cell , vol.17 , pp. 77-88
    • Turke, A.B.1
  • 93
    • 79953283356 scopus 로고    scopus 로고
    • Genetic interactions in cancer progression and treatment
    • Ashworth, A., Lord, C. J. & Reis-Filho, J. S. Genetic interactions in cancer progression and treatment. Cell 145, 30-38 (2011).
    • (2011) Cell , vol.145 , pp. 30-38
    • Ashworth, A.1    Lord, C.J.2    Reis-Filho, J.S.3
  • 94
    • 77952105211 scopus 로고    scopus 로고
    • Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate
    • Zhang, B. et al. Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate. Cancer Cell 17, 427-442 (2010).
    • (2010) Cancer Cell , vol.17 , pp. 427-442
    • Zhang, B.1
  • 95
    • 79956305728 scopus 로고    scopus 로고
    • BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition
    • Duy, C. et al. BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature 473, 384-388 (2011).
    • (2011) Nature , vol.473 , pp. 384-388
    • Duy, C.1
  • 96
    • 70350716805 scopus 로고    scopus 로고
    • Ecological therapy for cancer: Defining tumors using an ecosystem paradigm suggests new opportunities for novel cancer treatments
    • Pienta, K. J., McGregor, N., Axelrod, R. & Axelrod, D. E. Ecological therapy for cancer: defining tumors using an ecosystem paradigm suggests new opportunities for novel cancer treatments. Trans. Oncol. 1, 158-164 (2008).
    • (2008) Trans. Oncol. , vol.1 , pp. 158-164
    • Pienta, K.J.1    McGregor, N.2    Axelrod, R.3    Axelrod, D.E.4
  • 98
    • 79952392467 scopus 로고    scopus 로고
    • Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
    • Bissell, M. J. & Hines, W. C. Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nature Med. 17, 320-329 (2011).
    • (2011) Nature Med. , vol.17 , pp. 320-329
    • Bissell, M.J.1    Hines, W.C.2
  • 99
    • 38049160116 scopus 로고    scopus 로고
    • Competitive release and facilitation of drug-resistant parasites after therapeutic chemotherapy in a rodent malaria model
    • Wargo, A. R., Huijben, S., de Roode, J. C., Shepherd, J. & Read, A. F. Competitive release and facilitation of drug-resistant parasites after therapeutic chemotherapy in a rodent malaria model. Proc. Natl Acad. Sci. USA 104, 19914-19919 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 19914-19919
    • Wargo, A.R.1    Huijben, S.2    De Roode, J.C.3    Shepherd, J.4    Read, A.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.