Combinatorial drug therapy for cancer in the post-genomic era

Nature Biotechnology

Volumn 30, Issue 7, 2012, Pages 679-692

  Al Lazikani, Bissan ^a   Banerji, Udai ^a,b   Workman, Paul ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED RESISTANCE; CANCER DRUG; CYTOTOXIC; GENETIC HETEROGENEITIES; TUMOR CELLS; WHOLE GENOME SEQUENCING;

CHEMOTHERAPY; TUMORS;

DISEASES;

5 (2,4 DIHYDROXY 5 ISOPROPYLPHENYL) 4 (4 MORPHOLINOMETHYLPHENYL) 3 ISOXAZOLECARBOXYLIC ACID ETHYLAMIDE; ASOLAPARIB; CAPECITABINE; CETUXIMAB; CRIZOTINIB; CYCLOPHOSPHAMIDE; DABRAFENIB; DASATINIB; DEXAMETHASONE; DOCETAXEL; DOXORUBICIN; ERLOTINIB; EVEROLIMUS; FLUOROURACIL; GEFITINIB; GEMCITABINE; IMATINIB; IRINOTECAN; LAPATINIB; NAVELBINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PACLITAXEL; PERTUZUMAB; PLACEBO; RETINOIC ACID; RITUXIMAB; TRAMETINIB; TRASTUZUMAB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VEMURAFENIB; VINCRISTINE;

ADDICTION; BREAST CANCER; CANCER COMBINATION CHEMOTHERAPY; CANCER RESISTANCE; CANCER THERAPY; CHRONIC MYELOID LEUKEMIA; COLORECTAL CANCER; GASTROINTESTINAL STROMAL TUMOR; GENETIC HETEROGENEITY; GENOME; HUMAN; LUNG NON SMALL CELL CANCER; MELANOMA; MOLECULARLY TARGETED THERAPY; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; REVIEW; SEQUENCE ANALYSIS;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CLINICAL TRIALS AS TOPIC; COMBINED MODALITY THERAPY; DRUG DESIGN; GENETIC HETEROGENEITY; GENOME, HUMAN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INDIVIDUALIZED MEDICINE; METABOLIC NETWORKS AND PATHWAYS; MOLECULAR TARGETED THERAPY; NEOPLASMS;

EID: 84863651163     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2284     Document Type: Review

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