-
2
-
-
0033435103
-
Signalling networks that cause cancer
-
McCormick F. Signalling networks that cause cancer. Trends Biochem. Sci. 24:1999;M53.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 53
-
-
McCormick, F.1
-
4
-
-
0016176530
-
Errors in DNA replication as a basis of malignant changes
-
Loeb L.A.et al. Errors in DNA replication as a basis of malignant changes. Cancer Res. 34:1974;2311-2321.
-
(1974)
Cancer Res.
, vol.34
, pp. 2311-2321
-
-
Loeb, L.A.1
-
5
-
-
0026452949
-
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
-
Hartwell L. Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell. 71:1992;543-546.
-
(1992)
Cell
, vol.71
, pp. 543-546
-
-
Hartwell, L.1
-
6
-
-
0025773554
-
Mutator phenotype may be required for multistage carcinogenesis
-
Loeb L.A. Mutator phenotype may be required for multistage carcinogenesis. Cancer Res. 51:1991;3075-3079.
-
(1991)
Cancer Res.
, vol.51
, pp. 3075-3079
-
-
Loeb, L.A.1
-
7
-
-
0032542364
-
Genetic instabilities in human cancers
-
Lengauer C.et al. Genetic instabilities in human cancers. Nature. 396:1998;643-649.
-
(1998)
Nature
, vol.396
, pp. 643-649
-
-
Lengauer, C.1
-
8
-
-
0031004175
-
Genetic instability in colorectal cancers
-
Lengauer C.et al. Genetic instability in colorectal cancers. Nature. 386:1997;623-627.
-
(1997)
Nature
, vol.386
, pp. 623-627
-
-
Lengauer, C.1
-
9
-
-
0030948865
-
Mutations predisposing to hereditary nonpolyposis colorectal cancer
-
Peltomaki P., de la Chapelle A. Mutations predisposing to hereditary nonpolyposis colorectal cancer. Adv. Cancer Res. 71:1997;93-119.
-
(1997)
Adv. Cancer Res.
, vol.71
, pp. 93-119
-
-
Peltomaki, P.1
De La Chapelle, A.2
-
10
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
-
Ionov Y.et al. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature. 363:1993;558-561.
-
(1993)
Nature
, vol.363
, pp. 558-561
-
-
Ionov, Y.1
-
11
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau S.N.et al. Microsatellite instability in cancer of the proximal colon. Science. 260:1993;816-819.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
-
12
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen L.A.et al. Clues to the pathogenesis of familial colorectal cancer. Science. 260:1993;812-816.
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
-
13
-
-
0027137935
-
Hypermutability and mismatch repair deficiency in RER+ tumor cells
-
Parsons R.et al. Hypermutability and mismatch repair deficiency in RER+ tumor cells. Cell. 75:1993;1227-1236.
-
(1993)
Cell
, vol.75
, pp. 1227-1236
-
-
Parsons, R.1
-
14
-
-
0028224645
-
Mutator phenotypes in human colorectal carcinoma cell lines
-
Bhattacharyya N.P.et al. Mutator phenotypes in human colorectal carcinoma cell lines. Proc. Natl. Acad. Sci. U. S. A. 91:1994;6319-6323.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 6319-6323
-
-
Bhattacharyya, N.P.1
-
15
-
-
0028887597
-
Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer
-
Eshleman J.R.et al. Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer. Oncogene. 10:1995;33-37.
-
(1995)
Oncogene
, vol.10
, pp. 33-37
-
-
Eshleman, J.R.1
-
16
-
-
0028338927
-
The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle
-
Denko N.C.et al. The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle. Proc. Natl. Acad. Sci. U. S. A. 91:1994;5124-5128.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 5124-5128
-
-
Denko, N.C.1
-
17
-
-
0033616602
-
Transient excess of MYC activity can elicit genomic instability and tumorigenesis
-
Felsher D.W., Bishop J.M. Transient excess of MYC activity can elicit genomic instability and tumorigenesis. Proc. Natl. Acad. Sci. U. S. A. 96:1999;3940-3944.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 3940-3944
-
-
Felsher, D.W.1
Bishop, J.M.2
-
18
-
-
0026801062
-
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
-
Livingstone L.R.et al. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell. 70:1992;923-935.
-
(1992)
Cell
, vol.70
, pp. 923-935
-
-
Livingstone, L.R.1
-
19
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz F.et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science. 282:1998;1497-1501.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
-
20
-
-
0033564230
-
How aneuploidy affects metabolic control and causes cancer
-
Rasnick D., Duesberg P.H. How aneuploidy affects metabolic control and causes cancer. Biochem. J. 340:1999;621-630.
-
(1999)
Biochem. J.
, vol.340
, pp. 621-630
-
-
Rasnick, D.1
Duesberg, P.H.2
-
21
-
-
0032506125
-
Genetic instability of cancer cells is proportional to their degree of aneuploidy
-
Duesberg P.et al. Genetic instability of cancer cells is proportional to their degree of aneuploidy. Proc. Natl. Acad. Sci. U. S. A. 95:1998;13692-13697.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 13692-13697
-
-
Duesberg, P.1
-
22
-
-
0032546360
-
Mutations of mitotic checkpoint genes in human cancers
-
Cahill D.P.et al. Mutations of mitotic checkpoint genes in human cancers. Nature. 392:1998;300-303.
-
(1998)
Nature
, vol.392
, pp. 300-303
-
-
Cahill, D.P.1
-
23
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell P.C. The clonal evolution of tumor cell populations. Science. 194:1976;23-28.
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
24
-
-
0030592517
-
Lessons from hereditary colon cancer
-
Kinzler K.W., Vogelstein B. Lessons from hereditary colon cancer. Cell. 87:1996;159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
25
-
-
0003738147
-
-
K.W. Kinzler, & B. Vogelstein. McGraw-Hill
-
Bootsma D.et al. Kinzler K.W., Vogelstein B. The Genetic Basis of Human Cancer. 1998;245-274 McGraw-Hill.
-
(1998)
The Genetic Basis of Human Cancer
, pp. 245-274
-
-
Bootsma, D.1
-
26
-
-
0029814277
-
Molecular genetics of Bloom's syndrome
-
Ellis N.A., German J. Molecular genetics of Bloom's syndrome. Hum. Mol. Genet. 5:1996;1457-1463.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1457-1463
-
-
Ellis, N.A.1
German, J.2
-
27
-
-
0025899162
-
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
-
Nishisho I.et al. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science. 253:1991;665-669.
-
(1991)
Science
, vol.253
, pp. 665-669
-
-
Nishisho, I.1
-
28
-
-
0026920079
-
Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP)
-
Ichii S.et al. Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP). Hum. Mol. Genet. 1:1992;387-390.
-
(1992)
Hum. Mol. Genet.
, vol.1
, pp. 387-390
-
-
Ichii, S.1
-
29
-
-
0028051822
-
Inactivation of both APC alleles in human and mouse tumors
-
Levy D.B.et al. Inactivation of both APC alleles in human and mouse tumors. Cancer Res. 54:1994;5953-5958.
-
(1994)
Cancer Res.
, vol.54
, pp. 5953-5958
-
-
Levy, D.B.1
-
30
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
Morin P.J.et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science. 275:1997;1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
-
31
-
-
0032521433
-
Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer
-
Sparks A.B.et al. Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer. Cancer Res. 58:1998;1130-1134.
-
(1998)
Cancer Res.
, vol.58
, pp. 1130-1134
-
-
Sparks, A.B.1
-
32
-
-
0010945939
-
APC mutations in colorectal tumors with mismatch repair deficiency
-
Huang J.et al. APC mutations in colorectal tumors with mismatch repair deficiency. Proc. Natl. Acad. Sci. U. S. A. 93:1996;9049-9054.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 9049-9054
-
-
Huang, J.1
-
33
-
-
0025040233
-
Suppression of human colorectal carcinoma cell growth by wild-type p53
-
Baker S.J.et al. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science. 249:1990;912-915.
-
(1990)
Science
, vol.249
, pp. 912-915
-
-
Baker, S.J.1
-
34
-
-
0026515183
-
Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer
-
Goyette M.C.et al. Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer. Mol. Cell. Biol. 12:1992;1387-1395.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 1387-1395
-
-
Goyette, M.C.1
-
35
-
-
0027905014
-
Altered growth of human colon cancer cell lines disrupted at activated Ki-ras
-
Shirasawa S.et al. Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. Science. 260:1993;85-88.
-
(1993)
Science
, vol.260
, pp. 85-88
-
-
Shirasawa, S.1
-
36
-
-
0027936057
-
Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation
-
Koi M.et al. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. Cancer Res. 54:1994;4308-4312.
-
(1994)
Cancer Res.
, vol.54
, pp. 4308-4312
-
-
Koi, M.1
-
37
-
-
0033026714
-
Mechanisms of apoptosis avoidance in cancer
-
Reed J.C. Mechanisms of apoptosis avoidance in cancer. Curr. Opin. Oncol. 11:1999;68-75.
-
(1999)
Curr. Opin. Oncol.
, vol.11
, pp. 68-75
-
-
Reed, J.C.1
-
38
-
-
0030443140
-
The relevance of bacterial mutators to understanding human cancer
-
Miller J.H. The relevance of bacterial mutators to understanding human cancer. Cancer Surv. 28:1996;141-153.
-
(1996)
Cancer Surv.
, vol.28
, pp. 141-153
-
-
Miller, J.H.1
-
39
-
-
0027428093
-
The mutational meltdown in asexual populations
-
Lynch M.et al. The mutational meltdown in asexual populations. J. Hered. 84:1993;339-344.
-
(1993)
J. Hered.
, vol.84
, pp. 339-344
-
-
Lynch, M.1
-
40
-
-
0033555421
-
Diminishing returns from mutation supply rate in asexual populations
-
Arjan J.A.et al. Diminishing returns from mutation supply rate in asexual populations. Science. 283:1999;404-406.
-
(1999)
Science
, vol.283
, pp. 404-406
-
-
Arjan, J.A.1
-
41
-
-
0031023159
-
Proliferation of mutators in a cell population
-
Mao E.F.et al. Proliferation of mutators in a cell population. J. Bacteriol. 179:1997;417-422.
-
(1997)
J. Bacteriol.
, vol.179
, pp. 417-422
-
-
Mao, E.F.1
-
42
-
-
0030620273
-
Evolution of high mutation rates in experimental populations of E. coli
-
Sniegowski P.D.et al. Evolution of high mutation rates in experimental populations of E. coli. Nature. 387:1997;703-705.
-
(1997)
Nature
, vol.387
, pp. 703-705
-
-
Sniegowski, P.D.1
-
43
-
-
0030620272
-
Role of mutator alleles in adaptive evolution
-
Taddei F.et al. Role of mutator alleles in adaptive evolution. Nature. 387:1997;700-702.
-
(1997)
Nature
, vol.387
, pp. 700-702
-
-
Taddei, F.1
-
44
-
-
0031953260
-
The mutation rate and cancer
-
Jackson A.L., Loeb L.A. The mutation rate and cancer. Genetics. 148:1998;1483-1490.
-
(1998)
Genetics
, vol.148
, pp. 1483-1490
-
-
Jackson, A.L.1
Loeb, L.A.2
-
45
-
-
0032983538
-
Colorectal adenoma and cancer divergence: Evidence of multilineage progression
-
Tsao J.et al. Colorectal adenoma and cancer divergence: evidence of multilineage progression. Am. J. Pathol. 154:1999;1815-1824.
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 1815-1824
-
-
Tsao, J.1
-
46
-
-
0025941405
-
S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
-
Hoyt M.A.et al. S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell. 66:1991;507-517.
-
(1991)
Cell
, vol.66
, pp. 507-517
-
-
Hoyt, M.A.1
-
47
-
-
0026009964
-
Feedback control of mitosis in budding yeast
-
Li R., Murray A.W. Feedback control of mitosis in budding yeast. Cell. 66:1991;519-531.
-
(1991)
Cell
, vol.66
, pp. 519-531
-
-
Li, R.1
Murray, A.W.2
|