Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

Science

Volumn 346, Issue 6206, 2014, Pages 251-256

  De Bruin, Elza C ^a   McGranahan, Nicholas ^a,b   Mitter, Richard ^b   Salm, Max ^b   Wedge, David C ^c   Yates, Lucy ^c,d   Jamal Hanjani, Mariam ^a   Shafi, Seema ^a   Murugaesu, Nirupa ^a   Rowan, Andrew J ^b   Grönroos, Eva ^b   Muhammad, Madiha A ^a   Horswell, Stuart ^b   Gerlinger, Marco ^b   Varela, Ignacio ^e   Jones, David ^c   Marshall, John ^c   Voet, Thierry ^c,f   Van Loo, Peter ^c,f   Rassl, Doris M ^g   Rintoul, Robert C ^g   Janes, Sam M ^a   Lee, Siow Ming ^a,h   Forster, Martin ^a,h   Ahmad, Tanya ^h   Lawrence, David ^h   Falzon, Mary ^h   Capitanio, Arrigo ^h   Harkins, Timothy T ⁱ   Lee, Clarence C ⁱ   Tom, Warren ⁱ   Teefe, Enock ⁱ   Chen, Shann Ching ⁱ   Begum, Sharmin ^b   Rabinowitz, Adam ^b   Phillimore, Benjamin ^b   Spencer Dene, Bradley ^b   Stamp, Gordon ^b   Szallasi, Zoltan ^j,k   Matthews, Nik ^b   Stewart, Aengus ^b   Campbell, Peter ^c   Swanton, Charles ^a,b   more..

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e UNIVERSITY OF CANTABRIA   (Spain)

^f UNIVERSITY OF LEUVEN   (Belgium)

^g PAPWORTH HOSPITAL   (United Kingdom)

^h UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

ⁱ Thermo Fisher Scientific   (United States)

^j TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^k BOSTON CHILDREN S HOSPITAL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B MRNA EDITING ENZYME; CARCINOGEN; CYTIDINE DEAMINASE;

ARTICLE; CHEMICALLY INDUCED DISORDER; GENE DOSAGE; GENE TRANSLOCATION; GENETIC HETEROGENEITY; GENETICS; GENOMIC INSTABILITY; HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; MOLECULAR EVOLUTION; MUTATION; PROGNOSIS; SMOKING; TUMOR CELL CULTURE; TUMOR RECURRENCE;

CARCINOGENS; CARCINOMA, NON-SMALL-CELL LUNG; CYTIDINE DEAMINASE; EVOLUTION, MOLECULAR; GENE DOSAGE; GENETIC HETEROGENEITY; GENOMIC INSTABILITY; HUMANS; LUNG NEOPLASMS; MUTATION; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; SMOKING; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 84907855592     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1253462     Document Type: Article

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