Translocation mechanism of P-glycoprotein and conformational changes occurring at drug-binding site: Insights from multi-targeted molecular dynamics

Biochimica et Biophysica Acta - Biomembranes

Volumn 1838, Issue 11, 2014, Pages 2882-2898

  Prajapati, Rameshwar ^a   Sangamwar, Abhay T ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Multi targeted molecular dynamics; P glycoprotein; Translocation mechanism

Indexed keywords

MULTIDRUG RESISTANCE PROTEIN;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG BINDING SITE; INTRACELLULAR COUPLING HELIX; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; MOLECULAR STABILITY; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TARGETING; STRUCTURE ANALYSIS;

EID: 84931749019     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2014.07.018     Document Type: Article

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