Drug-stimulated ATPase activity of human P-glycoprotein requires movement between transmembrane segments 6 and 12

Journal of Biological Chemistry

Volumn 272, Issue 34, 1997, Pages 20986-20989

  Loo, Tip W ^a   Clarke, David M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; COLCHICINE; CYCLOSPORIN A; DITHIOTHREITOL; GLYCOPROTEIN P; VERAPAMIL; VINBLASTINE;

ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CROSS LINKING; CYTOTOXICITY; DISULFIDE BOND; ENZYME ACTIVATION; ENZYME ACTIVITY; HYDROPHOBICITY; MULTIDRUG RESISTANCE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; COLCHICINE; CROSS-LINKING REAGENTS; CYCLOSPORINE; CYSTEINE; HUMANS; MEMBRANE GLYCOPROTEINS; MOVEMENT; P-GLYCOPROTEIN; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; VERAPAMIL; VINBLASTINE;

ANIMALIA;

EID: 0030779102     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.34.20986     Document Type: Article

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