Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans

Nature

Volumn 490, Issue 7421, 2012, Pages 566-569

  Jin, Mi Sun ^a   Oldham, Michael L ^b   Zhang, Qiuju ^b   Chen, Jue ^a,b  

^a PURDUE UNIVERSITY   (United States)

^b Med Institute Inc Lafayette   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CAENORHABDITIS ELEGANS PROTEIN; DACTINOMYCIN; MULTIDRUG RESISTANCE PROTEIN; PACLITAXEL;

ABSORPTION; BIOCHEMISTRY; CANCER; CRYSTAL STRUCTURE; DRUG RESISTANCE; HYDROLYSIS; MEMBRANE; MUTATION; NEMATODE; PROTEIN; XENOBIOTICS;

ARTICLE; BINDING KINETICS; CAENORHABDITIS ELEGANS; CELL MEMBRANE; CRYSTAL STRUCTURE; CYTOPLASM; DRUG BINDING; DRUG SENSITIVITY; DRUG TRANSPORT; LIPID BILAYER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; PROTEIN TRANSPORT; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; CAENORHABDITIS ELEGANS; CRYSTALLOGRAPHY, X-RAY; DACTINOMYCIN; HUMANS; HYDROLYSIS; LIPID BILAYERS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; P-GLYCOPROTEIN; PACLITAXEL; PROTEIN STRUCTURE, TERTIARY; STRUCTURAL HOMOLOGY, PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP;

CAENORHABDITIS ELEGANS;

EID: 84867883248     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11448     Document Type: Article

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