A salt bridge in intracellular loop 2 is essential for folding of human P-glycoprotein

Biochemistry

Volumn 52, Issue 19, 2013, Pages 3194-3196

  Loo, Tip W ^a   Clarke, David M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS; HIGH-RESOLUTION STRUCTURES; HOMOLOGY MODELS; INTRACELLULAR LOOP 2; MODEL-BASED OPC; NUCLEOTIDE-BINDING DOMAIN; P-GLYCOPROTEIN; TRANS-MEMBRANE DOMAINS;

ACTIVATION ANALYSIS;

GLYCOPROTEINS;

ADENOSINE TRIPHOSPHATASE; ARGININE; GLUTAMIC ACID; MULTIDRUG RESISTANCE PROTEIN; SODIUM CHLORIDE;

AMINO ACID SEQUENCE; ARTICLE; CAENORHABDITIS ELEGANS; CRYSTAL STRUCTURE; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; INTRACELLULAR LOOP 2; INTRACELLULAR SPACE; MOUSE; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN FOLDING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CAENORHABDITIS ELEGANS PROTEINS; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; P-GLYCOPROTEIN; PROTEIN FOLDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; SALTS; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 84877763551     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400425k     Document Type: Article

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