ATP hydrolysis promotes interactions between the extracellular ends of transmembrane segments 1 and 11 of human multidrug resistance P-glycoprotein

Biochemistry

Volumn 44, Issue 30, 2005, Pages 10250-10258

  Loo, Tip W ^a   Bartlett, M Claire ^a   Clarke, David M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; CELLS; GENES; HYDROLYSIS;

CYTOTOXIC COMPOUNDS; GLYCOPROTEINS; NUCLEOTIDE-BINDING DOMAIN (NBD); TRANSMEMBRANE (TM);

GLYCOLS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CYCLOSPORIN A; CYSTEINE; GLYCOPROTEIN P; OXIDIZING AGENT; VERAPAMIL; VINBLASTINE;

ARTICLE; BINDING SITE; CELL MEMBRANE; CELL STRAIN HEK293; CONTROLLED STUDY; CROSS LINKING; EMBRYO; ENZYME SUBSTRATE; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; MUTAGENESIS; OXIDATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN HYDROLYSIS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENYLYL IMIDODIPHOSPHATE; BINDING SITES; CELL LINE; CROSS-LINKING REAGENTS; CYSTEINE; DISULFIDES; EXTRACELLULAR SPACE; HUMANS; HYDROLYSIS; ION CHANNEL GATING; MODELS, CHEMICAL; MUTAGENESIS, SITE-DIRECTED; P-GLYCOPROTEIN; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 23044503311     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050705j     Document Type: Article

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