Drug rescue distinguishes between different structural models of human P-glycoprotein

Biochemistry

Volumn 52, Issue 41, 2013, Pages 7167-7169

  Loo, Tip W ^a   Clarke, David M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS; ELEGANS; HIGH RESOLUTION CRYSTAL STRUCTURE; HOMOLOGY MODELS; MODEL-BASED OPC; P-GLYCOPROTEIN; STRUCTURAL MODELS; TRANSMEMBRANE SEGMENTS;

AMINO ACIDS; BIOLOGICAL MEMBRANES;

GLYCOPROTEINS;

ADENOSINE TRIPHOSPHATASE; ARGININE; CYCLOSPORIN A; LIPID; MULTIDRUG RESISTANCE PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING; ENZYME ACTIVITY; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; STRUCTURAL HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CYCLOSPORINE; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MUTATION; P-GLYCOPROTEIN; PROTEIN STRUCTURE, TERTIARY;

EID: 84886051978     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi401269m     Document Type: Article

References (21)

1. Sharom, F. J. (2006) Biochem. Cell Biol. 84, 979-992
2. Ambudkar, S. V., Dey, S., Hrycyna, C. A., Ramachandra, M., Pastan, I., and Gottesman, M. M. (1999) Annu. Rev. Pharmacol. Toxicol. 39, 361-398
3. Eckford, P. D. and Sharom, F. J. (2009) Chem. Rev. 109, 2989-3011
4. Pajeva, I. K., Globisch, C., and Wiese, M. (2009) FEBS J. 276, 7016-7026
5. Klepsch, F., Chiba, P., and Ecker, G. F. (2011) PLoS Comput. Biol. 7, e1002036
6. Bikadi, Z., Hazai, I., Malik, D., Jemnitz, K., Veres, Z., Hari, P., Ni, Z., Loo, T. W., Clarke, D. M., Hazai, E., and Mao, Q. (2011) PLoS One 6, e25815
7. Chen, C. J., Chin, J. E., Ueda, K., Clark, D. P., Pastan, I., Gottesman, M. M., and Roninson, I. B. (1986) Cell 47, 381-389
8. Loo, T. W., Bartlett, M. C., and Clarke, D. M. (2009) J. Biol. Chem. 284, 24074-24087
9. Loo, T. W., Bartlett, M. C., and Clarke, D. M. (2003) J. Biol. Chem. 278, 39706-39710
10. Loo, T. W. and Clarke, D. M. (1999) J. Biol. Chem. 274, 24759-24765
11. Jin, M. S., Oldham, M. L., Zhang, Q., and Chen, J. (2012) Nature 490, 566-569
12. Loo, T. W., Bartlett, M. C., and Clarke, D. M. (2003) J. Biol. Chem. 278, 20449-20452
13. Loo, T. W., Bartlett, M. C., and Clarke, D. M. (2007) J. Biol. Chem. 282, 32043-32052
14. Loo, T. W. and Clarke, D. M. (1997) J. Biol. Chem. 272, 709-712
15. Loo, T. W., Bartlett, M. C., and Clarke, D. M. (2004) Biochem. Biophys. Res. Commun. 325, 580-585
16. Dorairaj, S. and Allen, T. W. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 4943-4948
17. Aller, S. G., Yu, J., Ward, A., Weng, Y., Chittaboina, S., Zhuo, R., Harrell, P. M., Trinh, Y. T., Zhang, Q., Urbatsch, I. L., and Chang, G. (2009) Science 323, 1718-1722
18. Loo, T. W. and Clarke, D. M. (2013) Biochemistry 52, 5161-5163
19. Loo, T. W., Bartlett, M. C., and Clarke, D. M. (2004) Biochemistry 43, 12081-12089
20. Loo, T. W., Bartlett, M. C., and Clarke, D. M. (2011) Biochemistry 50, 672-685
21. Loo, T. W., Bartlett, M. C., and Clarke, D. M. (2013) Biochem. Pharmacol. 86, 612-619