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Volumn 275, Issue 50, 2000, Pages 39272-39278
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Identification of residues within the drug-binding domain of the human multidrug resistance P-glycoprotein by cysteine-scanning mutagenesis and reaction with dibromobimane
a a,b,c |
Author keywords
[No Author keywords available]
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Indexed keywords
ADENOSINE TRIPHOSPHATASE;
BROMOBIMANE;
COLCHICINE;
CYSTEINE;
CYTOTOXIC AGENT;
GLYCOPROTEIN P;
MEMBRANE PROTEIN;
MULTIDRUG RESISTANCE PROTEIN;
MUTANT PROTEIN;
VERAPAMIL;
VINBLASTINE;
AMINO ACID SEQUENCE;
ARTICLE;
CHEMICAL REACTION;
DRUG BINDING SITE;
DRUG STRUCTURE;
DRUG TRANSPORT;
EMBRYO;
ENZYME ACTIVITY;
ENZYME INHIBITION;
HUMAN;
HUMAN CELL;
MUTAGENESIS;
PRIORITY JOURNAL;
ADENOSINE TRIPHOSPHATASES;
AMINO ACID SEQUENCE;
ANTINEOPLASTIC AGENTS, PHYTOGENIC;
BICYCLO COMPOUNDS;
CALCIUM CHANNEL BLOCKERS;
COLCHICINE;
CROSS-LINKING REAGENTS;
CYSTEINE;
HUMANS;
IMMUNOBLOTTING;
KINETICS;
MODELS, BIOLOGICAL;
MOLECULAR SEQUENCE DATA;
MUTAGENESIS, SITE-DIRECTED;
P-GLYCOPROTEIN;
PROTEIN STRUCTURE, TERTIARY;
VERAPAMIL;
VINBLASTINE;
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EID: 0034671916
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.M007741200 Document Type: Article |
Times cited : (139)
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References (58)
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