-
1
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 2009; 324: 929-930. doi:10.1126/science.1169786.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
2
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 2009; 324: 930-935. doi:10.1126/science.1170116.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
-
3
-
-
34250317798
-
A new pyrimidine base from bacteriophage nucleic acids
-
Wyatt GR, Cohen SS. A new pyrimidine base from bacteriophage nucleic acids. Nature 1952; 170: 1072-1073. doi:10.1038/1701072a0.
-
(1952)
Nature
, vol.170
, pp. 1072-1073
-
-
Wyatt, G.R.1
Cohen, S.S.2
-
4
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 861-872. doi:10.1016/j.cell.2007.11.019.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
5
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-676. doi:10.1016/j.cell.2006.07.024.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
6
-
-
43749098985
-
DNA methylation landscapes: provocative insights from epigenomics
-
Suzuki MM, Bird A. DNA methylation landscapes: provocative insights from epigenomics. Nat Rev Genet 2008; 9: 465-476. doi:10.1038/nrg2341.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 465-476
-
-
Suzuki, M.M.1
Bird, A.2
-
7
-
-
84893716683
-
Non-CG methylation patterns shape the epigenetic landscape in Arabidopsis
-
Stroud H, Do T, Du J, et al. Non-CG methylation patterns shape the epigenetic landscape in Arabidopsis. Nat Struct Mol Biol 2014; 21: 64-72. doi:10.1038/nsmb.2735.
-
(2014)
Nat Struct Mol Biol
, vol.21
, pp. 64-72
-
-
Stroud, H.1
Do, T.2
Du, J.3
-
8
-
-
0019875880
-
Methylation of CpG sequences in eukaryotic DNA
-
Gruenbaum Y, Stein R, Cedar H, Razin A. Methylation of CpG sequences in eukaryotic DNA. FEBS Lett 1981; 124: 67-71. doi:10.1016/00145793(81)80055-5.
-
(1981)
FEBS Lett
, vol.124
, pp. 67-71
-
-
Gruenbaum, Y.1
Stein, R.2
Cedar, H.3
Razin, A.4
-
9
-
-
0027968172
-
Densely methylated DNA islands in mammalian chromosomal replication origins
-
Tasheva ES, Roufa DJ. Densely methylated DNA islands in mammalian chromosomal replication origins. Mol Cell Biol 1994; 14: 5636-5644. doi:10.1128/MCB.14.9.5636.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5636-5644
-
-
Tasheva, E.S.1
Roufa, D.J.2
-
10
-
-
0023655172
-
The majority of methylated deoxycytidines in human DNA are not in the CpG dinucleotide
-
Woodcock DM, Crowther PJ, Diver WP. The majority of methylated deoxycytidines in human DNA are not in the CpG dinucleotide. Biochem Biophys Res Commun 1987; 145: 888-894. doi:10.1016/0006-291X(87)91048-5.
-
(1987)
Biochem Biophys Res Commun
, vol.145
, pp. 888-894
-
-
Woodcock, D.M.1
Crowther, P.J.2
Diver, W.P.3
-
11
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, Pelizzola M, Dowen RH, et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009; 462: 315-322. doi:10.1038/nature08514.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
-
12
-
-
84857331867
-
Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome
-
Xie W, Barr CL, Kim A, et al. Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell 2012; 148: 816-831. doi:10.1016/j.cell.2011.12.035.
-
(2012)
Cell
, vol.148
, pp. 816-831
-
-
Xie, W.1
Barr, C.L.2
Kim, A.3
-
13
-
-
77649267695
-
Dynamic changes in the human methylome during differentiation
-
Laurent L, Wong E, Li G, et al. Dynamic changes in the human methylome during differentiation. Genome Res 2010; 20: 320-331. doi:10.1101/gr.101907.109.
-
(2010)
Genome Res
, vol.20
, pp. 320-331
-
-
Laurent, L.1
Wong, E.2
Li, G.3
-
14
-
-
0034625064
-
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
-
Ramsahoye BH, Biniszkiewicz D, Lyko F, Clark V, Bird AP, Jaenisch R. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci U S A 2000; 97: 5237-5242. doi:10.1073/pnas.97.10.5237.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5237-5242
-
-
Ramsahoye, B.H.1
Biniszkiewicz, D.2
Lyko, F.3
Clark, V.4
Bird, A.P.5
Jaenisch, R.6
-
15
-
-
84874624739
-
Dynamic DNA methylation across diverse human cell lines and tissues
-
Varley KE, Gertz J, Bowling KM, et al. Dynamic DNA methylation across diverse human cell lines and tissues. Genome Res 2013; 23: 555-567. doi:10.1101/gr.147942.112.
-
(2013)
Genome Res
, vol.23
, pp. 555-567
-
-
Varley, K.E.1
Gertz, J.2
Bowling, K.M.3
-
16
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992; 69: 915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
17
-
-
0029803192
-
De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells
-
Lei H, Oh SP, Okano M, et al. De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development 1996; 122: 3195-3205.
-
(1996)
Development
, vol.122
, pp. 3195-3205
-
-
Lei, H.1
Oh, S.P.2
Okano, M.3
-
18
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999; 99: 247-257. doi:10.1016/S0092-8674(00)81656-6.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
19
-
-
0036135014
-
Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements
-
Liang G, Chan MF, Tomigahara Y, et al. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol Cell Biol 2002; 22: 480-491.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 480-491
-
-
Liang, G.1
Chan, M.F.2
Tomigahara, Y.3
-
20
-
-
33745270104
-
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b
-
Tsumura A, Hayakawa T, Kumaki Y, et al. Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells 2006; 11: 805-814. doi:10.1111/j.1365-2443.2006.00984.x.
-
(2006)
Genes Cells
, vol.11
, pp. 805-814
-
-
Tsumura, A.1
Hayakawa, T.2
Kumaki, Y.3
-
21
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003; 33 Suppl: 245-254. doi:10.1038/ng1089.
-
(2003)
Nat Genet
, vol.33
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
22
-
-
84871586080
-
A molecular roadmap of reprogramming somatic cells into iPS cells
-
Polo JM, Anderssen E, Walsh RM, et al. A molecular roadmap of reprogramming somatic cells into iPS cells. Cell 2012; 151: 1617-1632. doi:10.1016/j.cell.2012.11.039.
-
(2012)
Cell
, vol.151
, pp. 1617-1632
-
-
Polo, J.M.1
Anderssen, E.2
Walsh, R.M.3
-
23
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
Mikkelsen TS, Hanna J, Zhang X, et al. Dissecting direct reprogramming through integrative genomic analysis. Nature 2008; 454: 49-55. doi:10.1038/nature07056.
-
(2008)
Nature
, vol.454
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
-
24
-
-
83255177149
-
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells
-
Kim K, Zhao R, Doi A, et al. Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat Biotechnol 2011; 29: 1117-1119. doi:10.1038/nbt.2052.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 1117-1119
-
-
Kim, K.1
Zhao, R.2
Doi, A.3
-
25
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
Kim K, Doi A, Wen B, et al. Epigenetic memory in induced pluripotent stem cells. Nature 2010; 467: 285-290. doi:10.1038/nature09342.
-
(2010)
Nature
, vol.467
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen, B.3
-
26
-
-
46949085597
-
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
-
Huangfu D, Maehr R, Guo W, et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 2008; 26: 795-797. doi:10.1038/nbt1418.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 795-797
-
-
Huangfu, D.1
Maehr, R.2
Guo, W.3
-
27
-
-
84859218238
-
Chromatin-modifying enzymes as modulators of reprogramming
-
Onder TT, Kara N, Cherry A, et al. Chromatin-modifying enzymes as modulators of reprogramming. Nature 2012; 483: 598-602. doi:10.1038/nature10953.
-
(2012)
Nature
, vol.483
, pp. 598-602
-
-
Onder, T.T.1
Kara, N.2
Cherry, A.3
-
28
-
-
79956318370
-
De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state
-
Pawlak M, Jaenisch R. De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state. Genes Dev 2011; 25: 1035-1040. doi:10.1101/gad.2039011.
-
(2011)
Genes Dev
, vol.25
, pp. 1035-1040
-
-
Pawlak, M.1
Jaenisch, R.2
-
29
-
-
84870058502
-
Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome
-
Soufi A, Donahue G, Zaret KS. Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Cell 2012; 151: 994-1004. doi:10.1016/j.cell.2012.09.045.
-
(2012)
Cell
, vol.151
, pp. 994-1004
-
-
Soufi, A.1
Donahue, G.2
Zaret, K.S.3
-
30
-
-
84899096353
-
The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation
-
Ding X, Wang X, Sontag S, et al. The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation. Stem Cells Dev 2014; 23: 931-940. doi:10.1089/scd.2013.0267.
-
(2014)
Stem Cells Dev
, vol.23
, pp. 931-940
-
-
Ding, X.1
Wang, X.2
Sontag, S.3
-
31
-
-
84874781927
-
Cell reprogramming requires silencing of a core subset of polycomb targets
-
Fragola G, Germain PL, Laise P, et al. Cell reprogramming requires silencing of a core subset of polycomb targets. PLoS Genet 2013; 9: e1003292. doi:10.1371/journal.pgen.1003292.
-
(2013)
PLoS Genet
, vol.9
, pp. e1003292
-
-
Fragola, G.1
Germain, P.L.2
Laise, P.3
-
32
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito S, Shen L, Dai Q, et al. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 2011; 333: 1300-1303. doi:10.1126/science.1210597.
-
(2011)
Science
, vol.333
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
-
33
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He YF, Li BZ, Li Z, et al. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 2011; 333: 1303-1307. doi:10.1126/science.1210944.
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
-
34
-
-
80053917872
-
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites
-
Maiti A, Drohat AC. Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. J Biol Chem 2011; 286: 35334-35338. doi:10.1074/jbc.C111.284620.
-
(2011)
J Biol Chem
, vol.286
, pp. 35334-35338
-
-
Maiti, A.1
Drohat, A.C.2
-
35
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz G, Branco MR, Seisenberger S, et al. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 2011; 473: 398-402. doi:10.1038/nature10008.
-
(2011)
Nature
, vol.473
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
-
36
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 2010; 466: 1129-1133. doi:10.1038/nature09303.
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
37
-
-
79551587102
-
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
-
Koh KP, Yabuuchi A, Rao S, et al. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 2011; 8: 200-213. doi:10.1016/j.stem.2011.01.008.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 200-213
-
-
Koh, K.P.1
Yabuuchi, A.2
Rao, S.3
-
38
-
-
84893373754
-
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells
-
Huang Y, Chavez L, Chang X, et al. Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells. Proc Natl Acad Sci U S A 2014; 111: 1361-1366. doi:10.1073/pnas.1322921111.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 1361-1366
-
-
Huang, Y.1
Chavez, L.2
Chang, X.3
-
39
-
-
84873707539
-
Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development
-
Dawlaty MM, Breiling A, Le T, et al. Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development. Dev Cell 2013; 24: 310-323. doi:10.1016/j.devcel.2012.12.015.
-
(2013)
Dev Cell
, vol.24
, pp. 310-323
-
-
Dawlaty, M.M.1
Breiling, A.2
Le, T.3
-
40
-
-
84898482006
-
Loss of tet enzymes compromises proper differentiation of embryonic stem cells
-
Dawlaty MM, Breiling A, Le T, et al. Loss of tet enzymes compromises proper differentiation of embryonic stem cells. Dev Cell 2014; 29: 102-111. doi:10.1016/j.devcel.2014.03.003.
-
(2014)
Dev Cell
, vol.29
, pp. 102-111
-
-
Dawlaty, M.M.1
Breiling, A.2
Le, T.3
-
41
-
-
84876946045
-
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics
-
Shen L, Wu H, Diep D, et al. Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics. Cell 2013; 153: 692-706. doi:10.1016/j.cell.2013.04.002.
-
(2013)
Cell
, vol.153
, pp. 692-706
-
-
Shen, L.1
Wu, H.2
Diep, D.3
-
42
-
-
84895911033
-
Regulation of TET protein stability by calpains
-
Wang Y, Zhang Y. Regulation of TET protein stability by calpains. Cell Reports 2014; 6: 278-284. doi:10.1016/j.celrep.2013.12.031.
-
(2014)
Cell Reports
, vol.6
, pp. 278-284
-
-
Wang, Y.1
Zhang, Y.2
-
43
-
-
84902831568
-
Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA
-
Pfaffeneder T, Spada F, Wagner M, et al. Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA. Nat Chem Biol 2014; 10: 574-581. doi:10.1038/nchembio.1532.
-
(2014)
Nat Chem Biol
, vol.10
, pp. 574-581
-
-
Pfaffeneder, T.1
Spada, F.2
Wagner, M.3
-
44
-
-
84875370281
-
NANOG-dependent function of TET1 and TET2 in establishment of pluripotency
-
Costa Y, Ding J, Theunissen TW, et al. NANOG-dependent function of TET1 and TET2 in establishment of pluripotency. Nature 2013; 495: 370-374. doi:10.1038/nature11925.
-
(2013)
Nature
, vol.495
, pp. 370-374
-
-
Costa, Y.1
Ding, J.2
Theunissen, T.W.3
-
45
-
-
84865486793
-
Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2
-
Doege CA, Inoue K, Yamashita T, et al. Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2. Nature 2012; 488: 652-655. doi:10.1038/nature11333.
-
(2012)
Nature
, vol.488
, pp. 652-655
-
-
Doege, C.A.1
Inoue, K.2
Yamashita, T.3
-
46
-
-
84875923762
-
Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming
-
Gao Y, Chen J, Li K, et al. Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming. Cell Stem Cell 2013; 12: 453-469. doi:10.1016/j.stem.2013.02.005.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 453-469
-
-
Gao, Y.1
Chen, J.2
Li, K.3
-
47
-
-
84878591266
-
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency
-
Wang T, Wu H, Li YJ, et al. Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency. Nat Cell Biol 2013; 15: 700. doi:10.1038/Ncb2748.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 700
-
-
Wang, T.1
Wu, H.2
Li, Y.J.3
-
48
-
-
84897989106
-
Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming
-
Hu X, Zhang L, Mao SQ, et al. Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming. Cell Stem Cell 2014; 14: 512-522. doi:10.1016/j.stem.2014.01.001.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 512-522
-
-
Hu, X.1
Zhang, L.2
Mao, S.Q.3
-
49
-
-
84880570961
-
MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling
-
Song SJ, Poliseno L, Song MS, et al. MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling. Cell 2013; 154: 311-324. doi:10.1016/j.cell.2013.06.026.
-
(2013)
Cell
, vol.154
, pp. 311-324
-
-
Song, S.J.1
Poliseno, L.2
Song, M.S.3
-
50
-
-
84880947688
-
Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a
-
Zhang P, Huang B, Xu X, Sessa WC. Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a. Biochem Biophys Res Commun 2013; 437: 368-373. doi:10.1016/j.bbrc.2013.06.082.
-
(2013)
Biochem Biophys Res Commun
, vol.437
, pp. 368-373
-
-
Zhang, P.1
Huang, B.2
Xu, X.3
Sessa, W.C.4
-
51
-
-
84891347361
-
Staged miRNA re-regulation patterns during reprogramming
-
Henzler CM, Li Z, Dang J, et al. Staged miRNA re-regulation patterns during reprogramming. Genome Biol 2013; 14: R149. doi:10.1186/gb-2013-14-12-r149.
-
(2013)
Genome Biol
, vol.14
, pp. R149
-
-
Henzler, C.M.1
Li, Z.2
Dang, J.3
-
52
-
-
84877693964
-
Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine
-
Minor EA, Court BL, Young JI, Wang G. Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine. J Biol Chem 2013; 288: 13669-13674. doi:10.1074/jbc.C113.464800.
-
(2013)
J Biol Chem
, vol.288
, pp. 13669-13674
-
-
Minor, E.A.1
Court, B.L.2
Young, J.I.3
Wang, G.4
-
53
-
-
84880344660
-
Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals
-
Yin R, Mao SQ, Zhao B, et al. Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals. J Am Chem Soc 2013; 135: 10396-10403. doi:10.1021/ja4028346.
-
(2013)
J Am Chem Soc
, vol.135
, pp. 10396-10403
-
-
Yin, R.1
Mao, S.Q.2
Zhao, B.3
-
54
-
-
84881476916
-
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells
-
Blaschke K, Ebata KT, Karimi MM, et al. Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. Nature 2013; 500: 222-226. doi:10.1038/nature12362.
-
(2013)
Nature
, vol.500
, pp. 222-226
-
-
Blaschke, K.1
Ebata, K.T.2
Karimi, M.M.3
-
55
-
-
84888372386
-
Vitamin C modulates TET1 function during somatic cell reprogramming
-
Chen J, Guo L, Zhang L, et al. Vitamin C modulates TET1 function during somatic cell reprogramming. Nat Genet 2013; 45: 1504-1509. doi:10.1038/ng.2807.
-
(2013)
Nat Genet
, vol.45
, pp. 1504-1509
-
-
Chen, J.1
Guo, L.2
Zhang, L.3
-
56
-
-
73049112178
-
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells
-
Esteban MA, Wang T, Qin B, et al. Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell 2010; 6: 71-79. doi:10.1016/j.stem.2009.12.001.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 71-79
-
-
Esteban, M.A.1
Wang, T.2
Qin, B.3
-
57
-
-
82755187396
-
The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner
-
Wang T, Chen K, Zeng X, et al. The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner. Cell Stem Cell 2011; 9: 575-587. doi:10.1016/j.stem.2011.10.005.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 575-587
-
-
Wang, T.1
Chen, K.2
Zeng, X.3
-
58
-
-
84862777034
-
Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells
-
S391-392
-
Stadtfeld M, Apostolou E, Ferrari F, et al. Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. Nat Genet 2012; 44: 398-405, S391-392. doi: 10.1038/ng.1110
-
(2012)
Nat Genet
, vol.44
, pp. 398-405
-
-
Stadtfeld, M.1
Apostolou, E.2
Ferrari, F.3
-
59
-
-
65549107163
-
Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver
-
Brunner AL, Johnson DS, Kim SW, et al. Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver. Genome Res 2009; 19: 1044-1056. doi:10.1101/gr.088773.108.
-
(2009)
Genome Res
, vol.19
, pp. 1044-1056
-
-
Brunner, A.L.1
Johnson, D.S.2
Kim, S.W.3
-
60
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A, Mikkelsen TS, Gu H, et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 2008; 454: 766-770. doi:10.1038/nature07107.
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
-
61
-
-
77953809032
-
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells
-
Hawkins RD, Hon GC, Lee LK, et al. Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell 2010; 6: 479-491. doi:10.1016/j.stem.2010.03.018.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 479-491
-
-
Hawkins, R.D.1
Hon, G.C.2
Lee, L.K.3
-
62
-
-
84878282421
-
Epigenomic analysis of multilineage differentiation of human embryonic stem cells
-
Xie W, Schultz MD, Lister R, et al. Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell 2013; 153: 1134-1148. doi:10.1016/j.cell.2013.04.022.
-
(2013)
Cell
, vol.153
, pp. 1134-1148
-
-
Xie, W.1
Schultz, M.D.2
Lister, R.3
-
63
-
-
78651280460
-
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
-
Song CX, Szulwach KE, Fu Y, et al. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol 2011; 29: 68-72. doi:10.1038/nbt.1732.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 68-72
-
-
Song, C.X.1
Szulwach, K.E.2
Fu, Y.3
-
64
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor WA, Pape UJ, Huang Y, et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 2011; 473: 394-397. doi:10.1038/nature10102.
-
(2011)
Nature
, vol.473
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
-
65
-
-
84861990517
-
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome
-
Yu M, Hon GC, Szulwach KE, et al. Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell 2012; 149: 1368-1380. doi:10.1016/j.cell.2012.04.027.
-
(2012)
Cell
, vol.149
, pp. 1368-1380
-
-
Yu, M.1
Hon, G.C.2
Szulwach, K.E.3
-
66
-
-
79959859654
-
Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells
-
Szulwach KE, Li X, Li Y, et al. Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells. PLoS Genet 2011; 7: e1002154. doi:10.1371/journal.pgen.1002154.
-
(2011)
PLoS Genet
, vol.7
, pp. e1002154
-
-
Szulwach, K.E.1
Li, X.2
Li, Y.3
-
67
-
-
84874267510
-
High-resolution enzymatic mapping of genomic 5-hydroxymethylcytosine in mouse embryonic stem cells
-
Sun Z, Terragni J, Borgaro JG, et al. High-resolution enzymatic mapping of genomic 5-hydroxymethylcytosine in mouse embryonic stem cells. Cell Reports 2013; 3: 567-576. doi:10.1016/j.celrep.2013.01.001.
-
(2013)
Cell Reports
, vol.3
, pp. 567-576
-
-
Sun, Z.1
Terragni, J.2
Borgaro, J.G.3
-
68
-
-
79952264847
-
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
-
Lister R, Pelizzola M, Kida YS, et al. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 2011; 471: 68-73. doi:10.1038/nature09798.
-
(2011)
Nature
, vol.471
, pp. 68-73
-
-
Lister, R.1
Pelizzola, M.2
Kida, Y.S.3
-
69
-
-
84867035018
-
Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells
-
Ruiz S, Diep D, Gore A, et al. Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells. Proc Natl Acad Sci U S A 2012; 109: 16196-16201. doi:10.1073/pnas.1202352109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 16196-16201
-
-
Ruiz, S.1
Diep, D.2
Gore, A.3
-
70
-
-
84873310426
-
Genome-wide chromatin state transitions associated with developmental and environmental cues
-
Zhu J, Adli M, Zou JY, et al. Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell 2013; 152: 642-654. doi:10.1016/j.cell.2012.12.033.
-
(2013)
Cell
, vol.152
, pp. 642-654
-
-
Zhu, J.1
Adli, M.2
Zou, J.Y.3
-
72
-
-
28444486367
-
Stem cell niche: structure and function
-
Li L, Xie T. Stem cell niche: structure and function. Annu Rev Cell Dev Biol 2005; 21: 605-631. doi:10.1146/annurev.cellbio.21.012704.131525.
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 605-631
-
-
Li, L.1
Xie, T.2
-
73
-
-
0344393410
-
Adult stem cell plasticity: fact or artifact?
-
Raff M. Adult stem cell plasticity: fact or artifact? Annu Rev Cell Dev Biol 2003; 19: 1-22. doi:10.1146/annurev.cellbio.19.111301.143037.
-
(2003)
Annu Rev Cell Dev Biol
, vol.19
, pp. 1-22
-
-
Raff, M.1
-
74
-
-
0034614576
-
Stem cells: units of development, units of regeneration, and units in evolution
-
Weissman IL. Stem cells: units of development, units of regeneration, and units in evolution. Cell 2000; 100: 157-168. doi:10.1016/S0092-8674(00)81692-X.
-
(2000)
Cell
, vol.100
, pp. 157-168
-
-
Weissman, I.L.1
-
75
-
-
18844396119
-
Embryonic stem cell differentiation: emergence of a new era in biology and medicine
-
Keller G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev 2005; 19: 1129-1155. doi:10.1101/gad.1303605.
-
(2005)
Genes Dev
, vol.19
, pp. 1129-1155
-
-
Keller, G.1
-
76
-
-
39349106325
-
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development
-
Murry CE, Keller G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 2008; 132: 661-680. doi:10.1016/j.cell.2008.02.008.
-
(2008)
Cell
, vol.132
, pp. 661-680
-
-
Murry, C.E.1
Keller, G.2
-
77
-
-
39149107803
-
Mechanisms and functional implications of adult neurogenesis
-
Zhao C, Deng W, Gage FH. Mechanisms and functional implications of adult neurogenesis. Cell 2008; 132: 645-660. doi:10.1016/j.cell.2008.01.033.
-
(2008)
Cell
, vol.132
, pp. 645-660
-
-
Zhao, C.1
Deng, W.2
Gage, F.H.3
-
78
-
-
0033515827
-
Multilineage potential of adult human mesenchymal stem cells
-
Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284: 143-147. doi:10.1126/science.284.5411.143.
-
(1999)
Science
, vol.284
, pp. 143-147
-
-
Pittenger, M.F.1
Mackay, A.M.2
Beck, S.C.3
-
79
-
-
0014744817
-
Ontogeny of the haemopoietic system: yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo
-
Moore MA, Metcalf D. Ontogeny of the haemopoietic system: yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo. Br J Haematol 1970; 18: 279-296.
-
(1970)
Br J Haematol
, vol.18
, pp. 279-296
-
-
Moore, M.A.1
Metcalf, D.2
-
80
-
-
38349179230
-
Of lineage and legacy: the development of mammalian hematopoietic stem cells
-
Dzierzak E, Speck NA. Of lineage and legacy: the development of mammalian hematopoietic stem cells. Nat Immunol 2008; 9: 129-136. doi:10.1038/ni1560.
-
(2008)
Nat Immunol
, vol.9
, pp. 129-136
-
-
Dzierzak, E.1
Speck, N.A.2
-
81
-
-
34247601504
-
Cell tracing shows the contribution of the yolk sac to adult haematopoiesis
-
Samokhvalov IM, Samokhvalova NI, Nishikawa S. Cell tracing shows the contribution of the yolk sac to adult haematopoiesis. Nature 2007; 446: 1056-1061. doi:10.1038/nature05725.
-
(2007)
Nature
, vol.446
, pp. 1056-1061
-
-
Samokhvalov, I.M.1
Samokhvalova, N.I.2
Nishikawa, S.3
-
82
-
-
0242268524
-
Osteoblastic cells regulate the haematopoietic stem cell niche
-
Calvi LM, Adams GB, Weibrecht KW, et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003; 425: 841-846. doi:10.1038/nature02040.
-
(2003)
Nature
, vol.425
, pp. 841-846
-
-
Calvi, L.M.1
Adams, G.B.2
Weibrecht, K.W.3
-
83
-
-
0242363225
-
Identification of the haematopoietic stem cell niche and control of the niche size
-
Zhang J, Niu C, Ye L, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003; 425: 836-841. doi:10.1038/nature02041.
-
(2003)
Nature
, vol.425
, pp. 836-841
-
-
Zhang, J.1
Niu, C.2
Ye, L.3
-
84
-
-
84866129506
-
Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice
-
Rossi L, Lin KK, Boles NC, et al. Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. Cell Stem Cell 2012; 11: 302-317. doi:10.1016/j.stem.2012.08.006.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 302-317
-
-
Rossi, L.1
Lin, K.K.2
Boles, N.C.3
-
85
-
-
5444224800
-
In vitro and in vivo expansion of hematopoietic stem cells
-
Sauvageau G, Iscove NN, Humphries RK. In vitro and in vivo expansion of hematopoietic stem cells. Oncogene 2004; 23: 7223-7232. doi:10.1038/sj.onc.1207942.
-
(2004)
Oncogene
, vol.23
, pp. 7223-7232
-
-
Sauvageau, G.1
Iscove, N.N.2
Humphries, R.K.3
-
86
-
-
34548208677
-
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation
-
Chambers SM, Shaw CA, Gatza C, Fisk CJ, Donehower LA, Goodell MA. Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol 2007; 5: e201. doi:10.1371/journal.pbio.0050201.
-
(2007)
PLoS Biol
, vol.5
, pp. e201
-
-
Chambers, S.M.1
Shaw, C.A.2
Gatza, C.3
Fisk, C.J.4
Donehower, L.A.5
Goodell, M.A.6
-
87
-
-
84875965163
-
Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging
-
Beerman I, Bock C, Garrison BS, Smith ZD, Gu H, Meissner A, Rossi DJ. Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging. Cell Stem Cell 2013; 12: 413-425. doi:10.1016/j.stem.2013.01.017.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 413-425
-
-
Beerman, I.1
Bock, C.2
Garrison, B.S.3
Smith, Z.D.4
Gu, H.5
Meissner, A.6
Rossi, D.J.7
-
88
-
-
84899768899
-
Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal
-
Sun D, Luo M, Jeong M, et al. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell 2014; 14: 673-688. doi:10.1016/j.stem.2014.03.002.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 673-688
-
-
Sun, D.1
Luo, M.2
Jeong, M.3
-
89
-
-
70350654370
-
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
-
Broske AM, Vockentanz L, Kharazi S, et al. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat Genet 2009; 41: 1207-1215. doi:10.1038/ng.463.
-
(2009)
Nat Genet
, vol.41
, pp. 1207-1215
-
-
Broske, A.M.1
Vockentanz, L.2
Kharazi, S.3
-
90
-
-
70349469788
-
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
-
Trowbridge JJ, Snow JW, Kim J, Orkin SH. DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell 2009; 5: 442-449. doi:10.1016/j.stem.2009.08.016.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 442-449
-
-
Trowbridge, J.J.1
Snow, J.W.2
Kim, J.3
Orkin, S.H.4
-
91
-
-
84925116257
-
Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells
-
Challen GA, Sun D, Mayle A, et al. Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells. Cell Stem Cell 2014; 15: 350-364. doi:10.1016/j.stem.2014.06.018.
-
(2014)
Cell Stem Cell
, vol.15
, pp. 350-364
-
-
Challen, G.A.1
Sun, D.2
Mayle, A.3
-
92
-
-
84555207349
-
Dnmt3a is essential for hematopoietic stem cell differentiation
-
Challen GA, Sun D, Jeong M, et al. Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet 2012; 44: 23-31. doi:10.1038/ng.1009.
-
(2012)
Nat Genet
, vol.44
, pp. 23-31
-
-
Challen, G.A.1
Sun, D.2
Jeong, M.3
-
93
-
-
80052284526
-
Ten-eleven-translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
-
Ko M, Bandukwala HS, An J, et al. Ten-eleven-translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proc Natl Acad Sci U S A 2011; 108: 14566-14571. doi:10.1073/pnas.1112317108.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 14566-14571
-
-
Ko, M.1
Bandukwala, H.S.2
An, J.3
-
94
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio K, Reavie L, Shih A, et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 2011; 20: 11-24. doi:10.1016/j.ccr.2011.06.001.
-
(2011)
Cancer Cell
, vol.20
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
-
95
-
-
80052285127
-
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
-
Li Z, Cai X, Cai CL, et al. Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies. Blood 2011; 118: 4509-4518. doi:10.1182/blood-2010-12-325241.
-
(2011)
Blood
, vol.118
, pp. 4509-4518
-
-
Li, Z.1
Cai, X.2
Cai, C.L.3
-
96
-
-
80055088609
-
TET2: epigenetic safeguard for HSC
-
Ko M, Rao A. TET2: epigenetic safeguard for HSC. Blood 2011; 118: 4501-4503. doi:10.1182/blood-2011-08-373357.
-
(2011)
Blood
, vol.118
, pp. 4501-4503
-
-
Ko, M.1
Rao, A.2
-
97
-
-
79960062301
-
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
-
Quivoron C, Couronne L, Della Valle V, et al. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 2011; 20: 25-38. doi:10.1016/j.ccr.2011.06.003.
-
(2011)
Cancer Cell
, vol.20
, pp. 25-38
-
-
Quivoron, C.1
Couronne, L.2
Della Valle, V.3
-
98
-
-
84894230669
-
TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model
-
Ge L, Zhang RP, Wan F, et al. TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model. Mol Cell Biol 2014; 34: 989-1002. doi:10.1128/MCB.01061-13.
-
(2014)
Mol Cell Biol
, vol.34
, pp. 989-1002
-
-
Ge, L.1
Zhang, R.P.2
Wan, F.3
-
99
-
-
84961291997
-
A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing
-
Gjini E, Mansour MR, Sander JD, et al. A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. Mol Cell Biol 2015; 35: 789-804. doi:10.1128/MCB.00971-14.
-
(2015)
Mol Cell Biol
, vol.35
, pp. 789-804
-
-
Gjini, E.1
Mansour, M.R.2
Sander, J.D.3
-
100
-
-
84887021053
-
An extensive network of TET2-targeting microRNAs regulates malignant hematopoiesis
-
Cheng J, Guo S, Chen S, et al. An extensive network of TET2-targeting microRNAs regulates malignant hematopoiesis. Cell Reports 2013; 5: 471-481. doi:10.1016/j.celrep.2013.08.050.
-
(2013)
Cell Reports
, vol.5
, pp. 471-481
-
-
Cheng, J.1
Guo, S.2
Chen, S.3
-
101
-
-
79961139741
-
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development
-
Dawlaty MM, Ganz K, Powell BE, et al. Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell 2011; 9: 166-175. doi:10.1016/j.stem.2011.07.010.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 166-175
-
-
Dawlaty, M.M.1
Ganz, K.2
Powell, B.E.3
-
102
-
-
84880366679
-
TET1 plays an essential oncogenic role in MLL-rearranged leukemia
-
Huang H, Jiang X, Li Z, et al. TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proc Natl Acad Sci U S A 2013; 110: 11994-11999. doi:10.1073/pnas.1310656110.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 11994-11999
-
-
Huang, H.1
Jiang, X.2
Li, Z.3
-
103
-
-
58549112780
-
Identity crisis for adult periventricular neural stem cells: subventricular zone astrocytes, ependymal cells or both?
-
Chojnacki AK, Mak GK, Weiss S. Identity crisis for adult periventricular neural stem cells: subventricular zone astrocytes, ependymal cells or both? Nat Rev Neurosci 2009; 10: 153-163. doi:10.1038/nrn2571.
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 153-163
-
-
Chojnacki, A.K.1
Mak, G.K.2
Weiss, S.3
-
104
-
-
0035499887
-
The development of neural stem cells
-
Temple S. The development of neural stem cells. Nature 2001; 414: 112-117. doi:10.1038/35102174.
-
(2001)
Nature
, vol.414
, pp. 112-117
-
-
Temple, S.1
-
105
-
-
0034712047
-
Mammalian neural stem cells
-
Gage FH. Mammalian neural stem cells. Science 2000; 287: 1433-1438. doi:10.1126/science.287.5457.1433.
-
(2000)
Science
, vol.287
, pp. 1433-1438
-
-
Gage, F.H.1
-
106
-
-
67649908864
-
Adult neural stem cells in the mammalian central nervous system
-
Ma DK, Bonaguidi MA, Ming GL, Song H. Adult neural stem cells in the mammalian central nervous system. Cell Res 2009; 19: 672-682. doi:10.1038/cr.2009.56.
-
(2009)
Cell Res
, vol.19
, pp. 672-682
-
-
Ma, D.K.1
Bonaguidi, M.A.2
Ming, G.L.3
Song, H.4
-
107
-
-
0033040497
-
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
-
Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 1999; 97: 703-716. doi:10.1016/S0092-8674(00)80783-7.
-
(1999)
Cell
, vol.97
, pp. 703-716
-
-
Doetsch, F.1
Caille, I.2
Lim, D.A.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
108
-
-
0030438734
-
The adult rat hippocampus contains primordial neural stem cells
-
Palmer TD, Takahashi J, Gage FH. The adult rat hippocampus contains primordial neural stem cells. Mol Cell Neurosci 1997; 8: 389-404. doi:10.1006/mcne.1996.0595.
-
(1997)
Mol Cell Neurosci
, vol.8
, pp. 389-404
-
-
Palmer, T.D.1
Takahashi, J.2
Gage, F.H.3
-
109
-
-
2542626091
-
Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells
-
Shen Q, Goderie SK, Jin L, et al. Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science 2004; 304: 1338-1340. doi:10.1126/science.1095505.
-
(2004)
Science
, vol.304
, pp. 1338-1340
-
-
Shen, Q.1
Goderie, S.K.2
Jin, L.3
-
110
-
-
0034595855
-
Generalized potential of adult neural stem cells
-
Clarke DL, Johansson CB, Wilbertz J, et al. Generalized potential of adult neural stem cells. Science 2000; 288: 1660-1663.
-
(2000)
Science
, vol.288
, pp. 1660-1663
-
-
Clarke, D.L.1
Johansson, C.B.2
Wilbertz, J.3
-
111
-
-
79956209852
-
Adult neurogenesis in the mammalian brain: significant answers and significant questions
-
Ming GL, Song H. Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 2011; 70: 687-702. doi:10.1016/j.neuron.2011.05.001.
-
(2011)
Neuron
, vol.70
, pp. 687-702
-
-
Ming, G.L.1
Song, H.2
-
112
-
-
23244458855
-
Adult neurogenesis in the mammalian central nervous system
-
Ming GL, Song H. Adult neurogenesis in the mammalian central nervous system. Annu Rev Neurosci 2005; 28: 223-250. doi:10.1146/annurev.neuro.28.051804.101459.
-
(2005)
Annu Rev Neurosci
, vol.28
, pp. 223-250
-
-
Ming, G.L.1
Song, H.2
-
113
-
-
77958605856
-
Epigenetic choreographers of neurogenesis in the adult mammalian brain
-
Ma DK, Marchetto MC, Guo JU, Ming GL, Gage FH, Song H. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat Neurosci 2010; 13: 1338-1344. doi:10.1038/nn.2672.
-
(2010)
Nat Neurosci
, vol.13
, pp. 1338-1344
-
-
Ma, D.K.1
Marchetto, M.C.2
Guo, J.U.3
Ming, G.L.4
Gage, F.H.5
Song, H.6
-
114
-
-
84902477907
-
Unlocking epigenetic codes in neurogenesis
-
Yao B, Jin P. Unlocking epigenetic codes in neurogenesis. Genes Dev 2014; 28: 1253-1271. doi:10.1101/gad.241547.114.
-
(2014)
Genes Dev
, vol.28
, pp. 1253-1271
-
-
Yao, B.1
Jin, P.2
-
116
-
-
0242300612
-
DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
-
Martinowich K, Hattori D, Wu H, et al. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 2003; 302: 890-893. doi:10.1126/science.1090842.
-
(2003)
Science
, vol.302
, pp. 890-893
-
-
Martinowich, K.1
Hattori, D.2
Wu, H.3
-
117
-
-
77950187447
-
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
-
Feng J, Zhou Y, Campbell SL, et al. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 2010; 13: 423-430. doi:10.1038/nn.2514.
-
(2010)
Nat Neurosci
, vol.13
, pp. 423-430
-
-
Feng, J.1
Zhou, Y.2
Campbell, S.L.3
-
118
-
-
16444381345
-
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
-
Feng J, Chang H, Li E, Fan G. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J Neurosci Res 2005; 79: 734-746. doi:10.1002/jnr.20404.
-
(2005)
J Neurosci Res
, vol.79
, pp. 734-746
-
-
Feng, J.1
Chang, H.2
Li, E.3
Fan, G.4
-
119
-
-
0028267714
-
Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice
-
Goto K, Numata M, Komura JI, Ono T, Bestor TH, Kondo H. Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation; Research in Biological Diversity 1994; 56: 39-44.
-
(1994)
Differentiation; Research in Biological Diversity
, vol.56
, pp. 39-44
-
-
Goto, K.1
Numata, M.2
Komura, J.I.3
Ono, T.4
Bestor, T.H.5
Kondo, H.6
-
120
-
-
34250643467
-
Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan
-
Nguyen S, Meletis K, Fu D, Jhaveri S, Jaenisch R. Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan. Developmental Dynamics: An Official Publication of the American Association of Anatomists 2007; 236: 1663-1676. doi:10.1002/dvdy.21176.
-
(2007)
Developmental Dynamics: An Official Publication of the American Association of Anatomists
, vol.236
, pp. 1663-1676
-
-
Nguyen, S.1
Meletis, K.2
Fu, D.3
Jhaveri, S.4
Jaenisch, R.5
-
121
-
-
77954842322
-
Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
-
Wu H, Coskun V, Tao J, et al. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 2010; 329: 444-448. doi:10.1126/science.1190485.
-
(2010)
Science
, vol.329
, pp. 444-448
-
-
Wu, H.1
Coskun, V.2
Tao, J.3
-
122
-
-
0037636512
-
Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function
-
Zhao X, Ueba T, Christie BR, et al. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc Natl Acad Sci U S A 2003; 100: 6777-6782. doi:10.1073/pnas.1131928100.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 6777-6782
-
-
Zhao, X.1
Ueba, T.2
Christie, B.R.3
-
123
-
-
55549108710
-
Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells
-
Li X, Barkho BZ, Luo Y, et al. Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells. J Biol Chem 2008; 283: 27644-27652. doi:10.1074/jbc.M804899200.
-
(2008)
J Biol Chem
, vol.283
, pp. 27644-27652
-
-
Li, X.1
Barkho, B.Z.2
Luo, Y.3
-
124
-
-
60749094831
-
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis
-
Ma DK, Jang MH, Guo JU, et al. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 2009; 323: 1074-1077. doi:10.1126/science.1166859.
-
(2009)
Science
, vol.323
, pp. 1074-1077
-
-
Ma, D.K.1
Jang, M.H.2
Guo, J.U.3
-
125
-
-
77956099873
-
Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation
-
Liu C, Teng ZQ, Santistevan NJ, et al. Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation. Cell Stem Cell 2010; 6: 433-444. doi:10.1016/j.stem.2010.02.017.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 433-444
-
-
Liu, C.1
Teng, Z.Q.2
Santistevan, N.J.3
-
126
-
-
77956114374
-
MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1
-
Smrt RD, Szulwach KE, Pfeiffer RL, et al. MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1. Stem Cells 2010; 28: 1060-1070. doi:10.1002/stem.431.
-
(2010)
Stem Cells
, vol.28
, pp. 1060-1070
-
-
Smrt, R.D.1
Szulwach, K.E.2
Pfeiffer, R.L.3
-
127
-
-
77950565107
-
Cross talk between microRNA and epigenetic regulation in adult neurogenesis
-
Szulwach KE, Li X, Smrt RD, et al. Cross talk between microRNA and epigenetic regulation in adult neurogenesis. J Cell Biol 2010; 189: 127-141. doi:10.1083/jcb.200908151.
-
(2010)
J Cell Biol
, vol.189
, pp. 127-141
-
-
Szulwach, K.E.1
Li, X.2
Smrt, R.D.3
-
128
-
-
78650826181
-
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates
-
Globisch D, Munzel M, Muller M, et al. Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS One 2010; 5: e15367. doi:10.1371/journal.pone.0015367.
-
(2010)
PLoS One
, vol.5
, pp. e15367
-
-
Globisch, D.1
Munzel, M.2
Muller, M.3
-
129
-
-
84937738273
-
5-Hydroxymethylcytosine: a new player in brain disorders?
-
Cheng Y, Bernstein A, Chen D, Jin P. 5-Hydroxymethylcytosine: a new player in brain disorders? Exp Neurol 2014. doi:10.1016/j.expneurol.2014.05.008.
-
(2014)
Exp Neurol
-
-
Cheng, Y.1
Bernstein, A.2
Chen, D.3
Jin, P.4
-
130
-
-
82255192294
-
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging
-
Szulwach KE, Li X, Li Y, et al. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci 2011; 14: 1607-1616. doi:10.1038/nn.2959.
-
(2011)
Nat Neurosci
, vol.14
, pp. 1607-1616
-
-
Szulwach, K.E.1
Li, X.2
Li, Y.3
-
131
-
-
84897994794
-
Diversity of two forms of DNA methylation in the brain
-
Chen Y, Damayanti NP, Irudayaraj J, Dunn K, Zhou FC. Diversity of two forms of DNA methylation in the brain. Frontiers in Genetics 2014; 5: 46. doi:10.3389/fgene.2014.00046.
-
(2014)
Frontiers in Genetics
, vol.5
, pp. 46
-
-
Chen, Y.1
Damayanti, N.P.2
Irudayaraj, J.3
Dunn, K.4
Zhou, F.C.5
-
132
-
-
84874771985
-
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives
-
Spruijt CG, Gnerlich F, Smits AH, et al. Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Cell 2013; 152: 1146-1159. doi:10.1016/j.cell.2013.02.004.
-
(2013)
Cell
, vol.152
, pp. 1146-1159
-
-
Spruijt, C.G.1
Gnerlich, F.2
Smits, A.H.3
-
133
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
Guo JU, Su Y, Zhong C, Ming GL, Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 2011; 145: 423-434. doi:10.1016/j.cell.2011.03.022.
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
134
-
-
84881178902
-
Tet1 regulates adult hippocampal neurogenesis and cognition
-
Zhang RR, Cui QY, Murai K, et al. Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell 2013; 13: 237-245. doi:10.1016/j.stem.2013.05.006.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 237-245
-
-
Zhang, R.R.1
Cui, Q.Y.2
Murai, K.3
-
135
-
-
84874252793
-
Dynamics of 5-hydroxymethylcytosine and chromatin marks in mammalian neurogenesis
-
Hahn MA, Qiu R, Wu X, et al. Dynamics of 5-hydroxymethylcytosine and chromatin marks in mammalian neurogenesis. Cell Reports 2013; 3: 291-300. doi:10.1016/j.celrep.2013.01.011.
-
(2013)
Cell Reports
, vol.3
, pp. 291-300
-
-
Hahn, M.A.1
Qiu, R.2
Wu, X.3
-
136
-
-
84870883633
-
Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development
-
Xu Y, Xu C, Kato A, et al. Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development. Cell 2012; 151: 1200-1213. doi:10.1016/j.cell.2012.11.014.
-
(2012)
Cell
, vol.151
, pp. 1200-1213
-
-
Xu, Y.1
Xu, C.2
Kato, A.3
-
137
-
-
84871938660
-
Reprogramming and the mammalian germline: the Weismann barrier revisited
-
Sabour D, Schöler HR. Reprogramming and the mammalian germline: the Weismann barrier revisited. Curr Opin Cell Biol 2012; 24: 716-723. doi:10.1016/j.ceb.2012.08.006.
-
(2012)
Curr Opin Cell Biol
, vol.24
, pp. 716-723
-
-
Sabour, D.1
Schöler, H.R.2
-
138
-
-
38349100549
-
Epigenetic events in mammalian germ-cell development: reprogramming and beyond
-
Sasaki H, Matsui Y. Epigenetic events in mammalian germ-cell development: reprogramming and beyond. Nat Rev Genet 2008; 2008: 129-140. doi:10.1038/nrg2295.
-
(2008)
Nat Rev Genet
, vol.2008
, pp. 129-140
-
-
Sasaki, H.1
Matsui, Y.2
-
139
-
-
84859002909
-
Parallel mechanisms of epigenetic reprogramming in the germline
-
Hackett JA, Zylicz JJ, Surani MA. Parallel mechanisms of epigenetic reprogramming in the germline. Trends Genet 2012; 28: 164-174. doi:10.1016/j.tig.2012.01.005.
-
(2012)
Trends Genet
, vol.28
, pp. 164-174
-
-
Hackett, J.A.1
Zylicz, J.J.2
Surani, M.A.3
-
140
-
-
84859519339
-
Global profiling of DNA methylation erasure in mouse primordial germ cells
-
Guibert S, Forne T, Weber M. Global profiling of DNA methylation erasure in mouse primordial germ cells. Genome Res 2012; 22: 633-641. doi:10.1101/gr.130997.111.
-
(2012)
Genome Res
, vol.22
, pp. 633-641
-
-
Guibert, S.1
Forne, T.2
Weber, M.3
-
141
-
-
84884136941
-
DNA demethylation in pluripotency and reprogramming: the role of tet proteins and cell division
-
Bagci H, Fisher Amanda G. DNA demethylation in pluripotency and reprogramming: the role of tet proteins and cell division. Cell Stem Cell 2013; 13: 265-269. doi:10.1016/j.stem.2013.08.005.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 265-269
-
-
Bagci, H.1
Fisher Amanda, G.2
-
142
-
-
84862518049
-
Germline stem cells: origin and destiny
-
Lehmann R. Germline stem cells: origin and destiny. Cell Stem Cell 2012; 10: 729-739. doi:10.1016/j.stem.2012.05.016.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 729-739
-
-
Lehmann, R.1
-
143
-
-
34247470199
-
Male germline stem cells: from mice to men
-
Brinster RL. Male germline stem cells: from mice to men. Science 2007; 316: 404-405. doi:10.1126/science.1137741.
-
(2007)
Science
, vol.316
, pp. 404-405
-
-
Brinster, R.L.1
-
144
-
-
33745606965
-
Ovulated oocytes in adult mice derive from non-circulating germ cells
-
Eggan K, Jurga S, Gosden R, Min IM, Wagers AJ. Ovulated oocytes in adult mice derive from non-circulating germ cells. Nature 2006; 441: 1109-1114. doi:10.1038/nature04929.
-
(2006)
Nature
, vol.441
, pp. 1109-1114
-
-
Eggan, K.1
Jurga, S.2
Gosden, R.3
Min, I.M.4
Wagers, A.J.5
-
145
-
-
2642522727
-
Plzf is required in adult male germ cells for stem cell self-renewal
-
Buaas FW, Kirsh AL, Sharma M, et al. Plzf is required in adult male germ cells for stem cell self-renewal. Nat Genet 2004; 36: 647-652. doi:10.1038/ng1366.
-
(2004)
Nat Genet
, vol.36
, pp. 647-652
-
-
Buaas, F.W.1
Kirsh, A.L.2
Sharma, M.3
-
146
-
-
84884471932
-
TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation
-
Kaas GA, Zhong C, Eason DE, et al. TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation. Neuron 2013; 79: 1086-1093. doi:10.1016/j.neuron.2013.08.032.
-
(2013)
Neuron
, vol.79
, pp. 1086-1093
-
-
Kaas, G.A.1
Zhong, C.2
Eason, D.E.3
-
147
-
-
15544371145
-
Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions
-
Kanatsu-Shinohara M, Miki H, Inoue K, et al. Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions. Biol Reprod 2005; 72: 985-991. doi:10.1095/biolreprod.104.036400.
-
(2005)
Biol Reprod
, vol.72
, pp. 985-991
-
-
Kanatsu-Shinohara, M.1
Miki, H.2
Inoue, K.3
-
148
-
-
9344246885
-
Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells
-
Kubota H, Avarbock MR, Brinster RL. Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells. Proc Natl Acad Sci U S A 2004; 101: 16489-16494. doi:10.1073/pnas.0407063101.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 16489-16494
-
-
Kubota, H.1
Avarbock, M.R.2
Brinster, R.L.3
-
149
-
-
33646336640
-
Pluripotency of spermatogonial stem cells from adult mouse testis
-
Guan K, Nayernia K, Maier LS, et al. Pluripotency of spermatogonial stem cells from adult mouse testis. Nature 2006; 440: 1199-1203. doi:10.1038/nature04697.
-
(2006)
Nature
, vol.440
, pp. 1199-1203
-
-
Guan, K.1
Nayernia, K.2
Maier, L.S.3
-
150
-
-
84905911865
-
Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis
-
Hammoud SS, Low DH, Yi C, Carrell DT, Guccione E, Cairns BR. Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis. Cell Stem Cell 2014; 15: 239-253. doi:10.1016/j.stem.2014.04.006.
-
(2014)
Cell Stem Cell
, vol.15
, pp. 239-253
-
-
Hammoud, S.S.1
Low, D.H.2
Yi, C.3
Carrell, D.T.4
Guccione, E.5
Cairns, B.R.6
-
151
-
-
84905911865
-
Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis
-
Hammoud Saher S, Low Diana HP, Yi C, Carrell Douglas T, Guccione E, Cairns Bradley R. Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis. Cell Stem Cell 2014; 15: 239-253. doi:10.1016/j.stem.2014.04.006.
-
(2014)
Cell Stem Cell
, vol.15
, pp. 239-253
-
-
Hammoud Saher, S.1
Low Diana, H.P.2
Yi, C.3
Carrell Douglas, T.4
Guccione, E.5
Cairns Bradley, R.6
-
152
-
-
33750874985
-
Gene expression dynamics during germline specification in mice identified by quantitative single-cell gene expression profiling
-
Yabuta Y, Kurimoto K, Ohinata Y, Seki Y, Saitou M. Gene expression dynamics during germline specification in mice identified by quantitative single-cell gene expression profiling. Biol Reprod 2006; 75: 705-716. doi:10.1095/biolreprod.106.053686.
-
(2006)
Biol Reprod
, vol.75
, pp. 705-716
-
-
Yabuta, Y.1
Kurimoto, K.2
Ohinata, Y.3
Seki, Y.4
Saitou, M.5
-
153
-
-
84871702441
-
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells
-
Seisenberger S, Andrews S, Krueger F, et al. The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol Cell 2012; 48: 849-862. doi:10.1016/j.molcel.2012.11.001.
-
(2012)
Mol Cell
, vol.48
, pp. 849-862
-
-
Seisenberger, S.1
Andrews, S.2
Krueger, F.3
-
154
-
-
84871438065
-
Tet1 controls meiosis by regulating meiotic gene expression
-
Yamaguchi S, Hong K, Liu R, et al. Tet1 controls meiosis by regulating meiotic gene expression. Nature 2012; 492: 443-447. doi:10.1038/nature11709.
-
(2012)
Nature
, vol.492
, pp. 443-447
-
-
Yamaguchi, S.1
Hong, K.2
Liu, R.3
-
155
-
-
84872770694
-
Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine
-
Hackett JA, Sengupta R, Zylicz JJ, et al. Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine. Science 2013; 339: 448-452. doi:10.1126/science.1229277.
-
(2013)
Science
, vol.339
, pp. 448-452
-
-
Hackett, J.A.1
Sengupta, R.2
Zylicz, J.J.3
-
156
-
-
77954345408
-
Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway
-
Hajkova P, Jeffries SJ, Lee C, Miller N, Jackson SP, Surani MA. Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science 2010; 329: 78-82. doi:10.1126/science.1187945.
-
(2010)
Science
, vol.329
, pp. 78-82
-
-
Hajkova, P.1
Jeffries, S.J.2
Lee, C.3
Miller, N.4
Jackson, S.P.5
Surani, M.A.6
-
157
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
Gu TP, Guo F, Yang H, et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 2011; 477: 606-610. doi:10.1038/nature10443.
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
Guo, F.2
Yang, H.3
-
158
-
-
79952713567
-
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
-
Wossidlo M, Nakamura T, Lepikhov K, et al. 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nat Commun 2011; 2: 241. doi:10.1038/ncomms1240.
-
(2011)
Nat Commun
, vol.2
, pp. 241
-
-
Wossidlo, M.1
Nakamura, T.2
Lepikhov, K.3
-
159
-
-
77249148019
-
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
-
Popp C, Dean W, Feng S, et al. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010; 463: 1101-1105. doi:10.1038/nature08829.
-
(2010)
Nature
, vol.463
, pp. 1101-1105
-
-
Popp, C.1
Dean, W.2
Feng, S.3
-
160
-
-
84896378030
-
DNA methylation is required for the control of stem cell differentiation in the small intestine
-
Sheaffer KL, Kim R, Aoki R, et al. DNA methylation is required for the control of stem cell differentiation in the small intestine. Genes Dev 2014; 28: 652-664. doi:10.1101/gad.230318.113.
-
(2014)
Genes Dev
, vol.28
, pp. 652-664
-
-
Sheaffer, K.L.1
Kim, R.2
Aoki, R.3
-
161
-
-
84878248139
-
DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus
-
Kaaij LTJ, van de Wetering M, Fang F, et al. DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus. Genome Biol 2013; 14: R50. doi:10.1186/gb-2013-14-5-r50.
-
(2013)
Genome Biol
, vol.14
, pp. R50
-
-
Kaaij, L.T.J.1
van de Wetering, M.2
Fang, F.3
-
162
-
-
84874498527
-
Aberrant upregulation of ASCL2 by promoter demethylation promotes the growth and resistance to 5-fluorouracil of gastric cancer cells
-
Kwon OH, Park JL, Baek SJ, et al. Aberrant upregulation of ASCL2 by promoter demethylation promotes the growth and resistance to 5-fluorouracil of gastric cancer cells. Cancer Sci 2013; 104: 391-397. doi:10.1111/cas.12076.
-
(2013)
Cancer Sci
, vol.104
, pp. 391-397
-
-
Kwon, O.H.1
Park, J.L.2
Baek, S.J.3
-
163
-
-
84907905879
-
Brief reports: a distinct DNA methylation signature defines breast cancer stem cells and predicts cancer outcome
-
El Helou R, Wicinski J, Guille A, et al. Brief reports: a distinct DNA methylation signature defines breast cancer stem cells and predicts cancer outcome. Stem Cells 2014; 32: 3031-3036. doi:10.1002/stem.1792.
-
(2014)
Stem Cells
, vol.32
, pp. 3031-3036
-
-
El Helou, R.1
Wicinski, J.2
Guille, A.3
-
164
-
-
84914113138
-
Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem cells
-
Frobel J, Hemeda H, Lenz M, et al. Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem cells. Stem Cell Reports 2014; 3: 414-422. doi:10.1016/j.stemcr.2014.07.003.
-
(2014)
Stem Cell Reports
, vol.3
, pp. 414-422
-
-
Frobel, J.1
Hemeda, H.2
Lenz, M.3
-
165
-
-
84883393151
-
Alteration of genic 5-hydroxymethylcytosine patterning in olfactory neurons correlates with changes in gene expression and cell identity
-
Colquitt BM, Allen WE, Barnea G, Lomvardas S. Alteration of genic 5-hydroxymethylcytosine patterning in olfactory neurons correlates with changes in gene expression and cell identity. Proc Natl Acad Sci U S A 2013; 110: 14682-14687. doi:10.1073/pnas.1302759110.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 14682-14687
-
-
Colquitt, B.M.1
Allen, W.E.2
Barnea, G.3
Lomvardas, S.4
-
166
-
-
0042132027
-
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
-
Chen T, Ueda Y, Dodge JE, Wang Z, Li E. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol Cell Biol 2003; 23: 5594-5605. doi:10.1128/MCB.23.16.5594-5605.2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5594-5605
-
-
Chen, T.1
Ueda, Y.2
Dodge, J.E.3
Wang, Z.4
Li, E.5
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