Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming

Cell Stem Cell

Volumn 12, Issue 4, 2013, Pages 453-469

  Gao, Yawei ^a,b   Chen, Jiayu ^a,b   Li, Ke ^b   Wu, Tong ^b   Huang, Bo ^b   Liu, Wenqiang ^b   Kou, Xiaochen ^b   Zhang, Yu ^b   Huang, Hua ^c   Jiang, Yonghua ^b   Yao, Chao ^b   Liu, Xiaolei ^b   Lu, Zhiwei ^b   Xu, Zijian ^b   Kang, Lan ^b   Chen, Jun ^b   Wang, Hailin ^c   Cai, Tao ^b   Gao, Shaorong ^a,b  

^a GRADUATE SCHOOL OF PEKING UNION MEDICAL COLLEGE   (China)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^c RESEARCH CENTER FOR ECO ENVIRONMENTAL SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; OXYGENASE; PROTEIN TET1; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ARTICLE; COLONY FORMATION; CORRELATION ANALYSIS; CPG ISLAND; DEMETHYLATION; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; GENE LOCUS; GENE OVEREXPRESSION; GENETIC ASSOCIATION; NUCLEAR REPROGRAMMING; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SOMATIC CELL; TRANSCRIPTION INITIATION;

5-METHYLCYTOSINE; ANIMALS; CYTOSINE; DNA METHYLATION; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INDUCED PLURIPOTENT STEM CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MODELS, BIOLOGICAL; NUCLEAR REPROGRAMMING; OCTAMER TRANSCRIPTION FACTOR-3; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; SOXB1 TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTOME;

EID: 84875923762     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2013.02.005     Document Type: Article

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